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A mechanism for sequentially loading and unloading a biopsy instrument includes a first wheel operatively connected with a cannula, the first wheel being rotatably mounted upon an axle such that the axle urges rotation of the first wheel in a first direction to transfer the cannula and the first whe

A mechanism for sequentially loading and unloading a biopsy instrument includes a first wheel operatively connected with a cannula, the first wheel being rotatably mounted upon an axle such that the axle urges rotation of the first wheel in a first direction to transfer the cannula and the first wheel to a loaded position, the first wheel being configured for selective rotation with respect to the axle in a second direction to transfer the cannula and the first wheel to an unloaded position. A second wheel is operatively connected with a stylet, the second wheel being configured to be rotated by the axle in the first direction when the first wheel is in the loaded position, the second wheel configured for rotation relative to the axle to transfer the stylet and second wheel from the loaded to unloaded position. The second wheel is operatively engaged with the first wheel to allow partial rotation of the second wheel in the second direction with respect to the first wheel and urging similar rotation of the first wheel in the second direction after at least some duration of relative rotation of the second wheel with respect to the second wheel.

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1. A biopsy instrument for obtaining a tissue biopsy sample, comprising: a housing that movably supports one or more elongate stylets and one or more elongate cannulas, each cannula comprising a lumen through which one of the one or more stylets is movably disposed therethrough;an operator rotatably

1. A biopsy instrument for obtaining a tissue biopsy sample, comprising: a housing that movably supports one or more elongate stylets and one or more elongate cannulas, each cannula comprising a lumen through which one of the one or more stylets is movably disposed therethrough;an operator rotatably mounted to the housing about an axis and fixed to an axle;a first wheel rotatable about the axis and in selective rotational connection with the axle, the first wheel operatively engaged with the one or more cannulas to cause translation of the one or more cannulas with rotation of the first wheel;a second wheel rotatable about the axis and in selective rotational connection with the axle, the second wheel operatively engaged with the one or more stylets to cause translation of the one or more stylets with rotation of the second wheel;a shuttle disposed within the housing and in selective connection with the first and second wheels, the shuttle being translatable about the housing, the shuttle comprising a pin that is received within a first slot defined about an outer circumference of the first wheel and selectively engageable with the second wheel to selectively allow torque transfer from the axle to the second wheel. 2. The biopsy instrument of claim 1, wherein the shuttle is translatable about the housing in a direction parallel to the axis. 3. The biopsy instrument of claim 1, further comprising a first connecting rod pivotably connected to the first wheel at a proximal end thereof and pivotably connected to a cannula carrier at a distal end thereof, the cannula carrier being fixedly connected to the one or more cannulas, and further comprising a second connecting rod pivotably connected to the second wheel at a proximal end thereof and pivotably connected to a stylet carrier at a distal end thereof, the stylet carrier fixedly connected to the one or more stylets. 4. The biopsy instrument of claim 3, wherein the first and second connecting rods are biased into a forward position and the first and second connecting rods are each separately translatable to a rear position where pivot connections in the proximal and distal ends of each of the respective first and second connecting rods are each aligned along a line that travels through the axis. 5. The biopsy instrument of claim 4, wherein the second wheel includes a pin that is received within an arcuate second slot disposed upon a side surface of the first wheel to allow limited rotation of the second wheel with respect to the first wheel and cause simultaneous rotation of the first and second wheels when the pin contacts an end of the second slot. 6. The biopsy instrument of claim 4, wherein the first slot is disposed upon the circumferential edge of the first wheel along an arc length that defines the arc length of rotation of the first wheel as the first connecting rod translates from the forward position to the rear position. 7. The biopsy instrument of claim 6, wherein at least a portion of the first slot is arcuately disposed upon the circumferential edge of the first wheel such that a first end of the first slot is proximate a first side surface of the first wheel and an opposite second end of the first slot is proximate an opposite second side surface of the first wheel, wherein engagement between the pin and the first slot causes the shuttle to translate as the first wheel rotates from a first position where the first connecting rod is in the forward position to a second position disposed away from the first side of the first wheel when the first connecting rod is in the rear position. 8. The biopsy instrument of claim 7, wherein the second wheel pivotably carries a movable pawl that contacts the shuttle, wherein the shuttle aligns the pawl in a first configuration to prevent rotational connection between the axle and second wheel when the shuttle is in the first position. 9. The biopsy instrument of claim 8, wherein translation of the shuttle to the second position aligns the pawl in a second configuration to allow rotational connection between the axle and second wheel. 10. The biopsy instrument of claim 4, wherein the biopsy instrument is configured such that a first rotation of the operator from a rest position urges the first connecting rod into the rear position and a subsequent second rotation of the operator from the rest position urges the second connecting rod into the rear position. 11. The biopsy instrument of claim 4, wherein each of the first and second wheels comprise a cutout upon a portion of an outer circumferential surface thereof, wherein the housing further comprises a lever movably disposed upon the housing, wherein the lever is configured to be selectively transferred and retained in a position with a portion thereof extending within the cutouts upon the first and second wheels when the first and second connecting rods are each in the second rear position. 12. The biopsy instrument of claim 4, further comprising a slider disposed within the housing and in registry with a boss extending from an outer surface of the second wheel when the second connecting rod is in the rear position, wherein the slider and boss are configured such that selective translation of the slider with respect to the housing impacts the boss and urges rotation of the second wheel allowing translation of the second connecting rod away from the rear position and toward the forward position. 13. A biopsy instrument comprising: a housing enclosing a translatable cannula carrier and a translatable stylet carrier, the stylet carrier disposed within at least a portion of the cannula carrier;one or more stylets fixed to the stylet carrier with a portion extending from the housing and one or more cannulas fixed to the cannula carrier, the one or more cannulas each extending from the housing with each of the one or more cannulas receiving a portion of one of the one or more stylets within a lumen of the cannula;a stylet and cannula operation mechanism comprising: a first wheel rotatably disposed within the housing upon an axle and a second wheel rotatably disposed within the housing upon the axle and rotatable with respect to the first wheel;a first connecting rod pivotably connected to each of the first wheel and the cannula carrier on opposite ends thereof and a second connecting rod pivotably connected to the second wheel and the stylet carrier on opposite ends thereof;an operator rotatably disposed upon the housing and configured such that a first rotation of the operator in a first direction from a rest position causes the first wheel to rotate in the first direction until a line through the opposite ends of the first connecting rod extends through the axle, and such that a second rotation of the operator in the first direction causes the second wheel to rotate in the first direction until a second line through the opposite ends of the second connecting rod extends through the axle. 14. The biopsy instrument of claim 13, wherein the second wheel comprises a pin that extends from an inner side surface of the second wheel and into an arcuate slot disposed upon an inner side surface of the first wheel, such that the second wheel is capable of rotation in a second direction opposite the first direction for an arc length within the arcuate slot and with additional rotation of the second wheel in the second direction the first wheel rotates along with the second wheel. 15. The biopsy instrument of claim 13, wherein the first wheel comprises a second slot disposed upon an outer circumferential surface thereof, wherein a first portion of the second slot is proximate an inner side surface of the first wheel and a second portion of the second slot is proximate an opposite outer side surface of the first wheel, wherein the second slot receives a pin that extends from a shuttle translatably disposed within the housing, such that the shuttle is in a first position when the pin is disposed in the first portion of the slot and is urged to a second position when the pin is disposed in the second portion of the slot. 16. The biopsy instrument of claim 15, wherein the second wheel comprises a movable pawl biased into a first outward position to prevent engagement between the operator and the second wheel through an axle fixed to the operator when the shuttle is in the first position, and the shuttle urges the pawl toward a second downwardly extending position as the shuttle translates toward the second position allowing engagement between the axle and the second wheel. 17. A mechanism for sequentially loading and unloading a biopsy instrument, comprising: a first wheel operatively connected with a cannula, the first wheel rotatably mounted upon an axle such that the axle urges rotation of the first wheel in a first direction to transfer the cannula and the first wheel to a loaded position, the first wheel configured for selective rotation with respect to the axle in a second direction to transfer the cannula and the first wheel to an unloaded position;a second wheel operatively connected with a stylet, the second wheel being configured to be rotated by the axle in the first direction when the first wheel is in the loaded position, the second wheel configured for rotation relative to the axle to transfer the stylet and second wheel from the loaded to unloaded position;wherein the second wheel is operatively engaged with the first wheel to allow partial rotation of the second wheel in the second direction with respect to the first wheel and urging similar rotation of the first wheel in the second direction after at least some duration of relative rotation of the second wheel with respect to the first wheel. 18. The mechanism of claim 17, further comprising a shuttle that is slidably mounted with respect to an outer circumferential surface of each of the first and second wheels, the shuttle including a portion engaged with a portion of the first wheel to allow partial rotation of the first wheel but prevent full rotation of the first wheel. 19. The mechanism of claim 18, wherein the shuttle is slidable in a direction parallel to a rotational axis of the first and second wheels and is urged to slide with respect to the first and second wheels in response to rotation for the first wheel, wherein the shuttle is in a first position preventing engagement between the second wheel and the axle when the first wheel is in the unloaded position, and the shuttle is in a second position allowing engagement between the second wheel and the axle when the first wheel is in the loaded position. 20. The mechanism of claim 17, further comprising a firing mechanism disposed in concert with the first and second wheels, wherein the firing mechanism comprises a fork with a proximal end that is proximate to a peg upon the second wheel when the second wheel is in the loaded position, wherein the fork is configured to be urged toward the peg to impart a torque upon the second wheel in the second direction. 21. The mechanism of claim 17, further comprising a safety disposed in concert with the first and second wheels, wherein the safety comprises a movable lever with a bulged portion, wherein each of the first and second wheels comprise a cutout defined upon a portion of the outer circumferential surface thereof and when the first and second wheels are in the loaded position the respective cutouts in the first and second wheels are each configured to receive the bulged portion within a void defined by the cutouts.