최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0549596 (2006-10-13) |
등록번호 | US-8352025 (2013-01-08) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 68 인용 특허 : 430 |
A leadless cardiac pacemaker configured for implantation in electrical contact with a left ventricular cardiac chamber and configured for leadless triggered left-ventricular pacing for cardiac resynchronization therapy (CRT) in response to conducted signals from a pulse generator.
1. A cardiac pacing system comprising: a leadless cardiac pacemaker configured for implantation in electrical contact with a left ventricular cardiac chamber and performing leadless triggered left-ventricular pacing for cardiac resynchronization therapy (CRT) in response to conducted signals from a
1. A cardiac pacing system comprising: a leadless cardiac pacemaker configured for implantation in electrical contact with a left ventricular cardiac chamber and performing leadless triggered left-ventricular pacing for cardiac resynchronization therapy (CRT) in response to conducted signals from a co-implanted pulse generator, the leadless cardiac pacemaker comprising a pacing pulse generator configured to generate pulses adapted to perform cardiac pacing and pulses encoding information for transmission as communication signals during a refractory period, the leadless cardiac pacemaker configured to receive communication directly from a non-implanted programmer. 2. The system according to claim 1 further comprising: at least one implanted leadless or electrode-lead pulse generator comprising the co-implanted pulse generator, the co-implanted pulse generator being configured to generate pulses adapted to perform cardiac pacing and pulses adapted to encode information for transmission as communication signals to the leadless cardiac pacemaker. 3. The system according to claim 1 wherein the leadless cardiac pacemaker is configured for operation as a left-ventricular pacemaker for cardiac resynchronization therapy in response to wireless conducted signals from the co-implanted pulse generator, the wireless conducted signals being conducted pacing pulse, refractory and/or subliminal signals delivered in response to cardiac contractions, the leadless cardiac pacemaker programmable for operation as the left-ventricular pacemaker by bidirectional communication with a non-implanted programmer wherein information comprising programmable parameter settings is encoded in pulses generated by the pacing pulse generator. 4. The system according to claim 1 wherein the leadless cardiac pacemaker further comprises: a hermetic housing configured for placement on or attachment to the inside or outside of a cardiac chamber; andat least two electrodes abutting or adjacent to the housing and configured for delivering the pulses from the pacing pulse generator and for receiving triggering signals from the co-implanted pulse generator. 5. The system according to claim 4 wherein the at least two electrodes are configured for sensing electrical activity from cardiac chamber muscle. 6. The system according to claim 4 wherein the at least two electrodes are configured for bidirectional communication with at least one other device. 7. The system according to claim 1 further comprising: the leadless cardiac pacemaker configured for leadless triggered left-ventricular pacing in response to conducted signals selected from a group consisting of a signal from a separate implanted pulse generator, a signal from at least one electrode-lead of a separate implanted pulse generator, a right-ventricular pacing pulse delivered by an implanted pulse generator, an atrial pacing pulse delivered by an implanted pulse generator, a signal delivered in combination with a cardioversion function, and a signal delivered in combination with a defibrillation function. 8. The system according to claim 1 further comprising: the leadless cardiac pacemaker configured to operate as a “slave” left-ventricular leadless cardiac pacemaker wherein the leadless cardiac pacemaker is triggered by an atrial pacing stimulation pulse or right-ventricular pacing stimulation pulse of the co-implanted pulse generator operative for right-ventricular and/or atrial pacing. 9. The system according to claim 1 further comprising: the leadless pacemaker configured for implantation adjacent to the inside or outside wall of a cardiac chamber and configured for leadless conductive communication with the co-implanted pulse generator. 10. The system according to claim 1 further comprising: the leadless pacemaker configured for left-ventricular pacing triggered by conducted communication from the co-implanted pulse generator, the left-ventricular pacing triggered by a right-ventricular pacing pulse and/or an atrial pacing pulse delivered by the co-implanted pulse generator. 11. The system according to claim 1 further comprising: at least two electrodes abutting or adjacent to the housing and configured for delivering pulses generated by the pacing pulse generator and configured for operation as an incoming communication channel for receiving triggering information from the co-implanted pulse generator, the triggering information comprising an electrical signal resulting from a right-ventricular pacing stimulation pulse or an atrial pacing stimulation pulse of an implanted pulse generator and electrode-lead system. 12. The system according to claim 11 further comprising: a controller coupled to the at least two electrodes adapted to examine triggering information validity and, for a valid condition, activating delivery of a pacing stimulation pulse following a predetermined delay of zero or more milliseconds. 13. The system according to claim 11 further comprising: the incoming communication channel that communicates information selected from a group consisting of pacing rate, pulse duration, sensing threshold, delay intervals, refractory time intervals, stimulation pulse amplitudes, and parameters commonly programmed from an external programmer in a pacemaker; andthe at least two electrodes configured for operation as an outgoing communication channel adapted to communicate information encoded in at least one pulse generated by the pacing pulse generator and selected from a group consisting of programmable parameter settings, pacing and sensing event counts, battery voltage, battery current, information commonly displayed by external programmers used with pacemakers, and echoed information from the incoming channel to confirm correct programming. 14. The system according to claim 11 further comprising: a controller coupled to the at least two electrodes adapted to examine signals received on the at least two electrodes, decode information encoded in the signals, and evaluate the decoded information for pacing pulse signature validation. 15. The system according to claim 11 further comprising: a controller coupled to the at least two electrodes adapted to examine output pulse duration from the co-implanted pulse generator for usage as a signature for determining triggering information validity and, for a signature arriving within predetermined limits, activating delivery of a pacing pulse following a predetermined delay of zero or more milliseconds, the predetermined delay being determined from a method in a group consisting of preset at manufacture, programmed via an external programmer, and adaptively monitoring and conforming to duration of a triggering signal. 16. The system according to claim 11 further comprising: a controller coupled to the at least two electrodes adapted to examine output pulse amplitude, duration, and rate from the co-implanted pulse generator for usage as a signature for determining triggering information validity and, for a signature arriving within predetermined limits, activating delivery of a pacing pulse following a predetermined delay of zero or more milliseconds. 17. The system according to claim 11 further comprising: a controller coupled to the at least two electrodes adapted to trigger delivery of a left-ventricular pacing pulse from an atrial pacing pulse of the co-implanted pulse generator for cardiac resynchronization therapy (CRT) after a selected atrio-ventricular delay of 50 to 300 milliseconds, the controller further adapted to vary the atrio-ventricular delay according to time since a last delivered left-ventricular pacing pulse wherein a shorter atrio-ventricular delay is selected for a higher atrial rate. 18. A cardiac pacing system comprising: a leadless cardiac pacemaker configured for implantation in electrical contact with a cardiac chamber and configured for receiving and evaluating triggering information from a co-implanted pulse generator via an electrical signal conducted from an atrial or ventricular pacing pulse delivered by the co-implanted implanted pulse generator, the leadless cardiac pacemaker comprising a pacing pulse generator configured to generate pulses adapted to perform cardiac pacing and pulses encoding information for transmission as communication signals during a refractory period, the leadless cardiac pacemaker configured to receive communication directly from a non-implanted programmer. 19. The system according to claim 18 further comprising: at least one implanted leadless or electrode-lead pulse generator comprising the co-implanted pulse generator and configured to conduct signals that trigger left-ventricular pacing to the leadless cardiac pacemaker by direct conduction using modulated signals. 20. The system according to claim 18 wherein the leadless cardiac pacemaker further comprises: a hermetic housing configured for placement on or attachment to the inside or outside of a cardiac chamber; andat least two electrodes abutting or adjacent to the housing and configured for delivering the pulses from the pacing pulse generator and for receiving triggering signals from the co-implanted pulse generator. 21. The system according to claim 20 wherein the at least two electrodes are configured for operation as an incoming communication channel for receiving triggering signals from the co-implanted pulse generator, the triggering information comprising a signal resulting from a pulse generated by the co-implanted pulse generator. 22. The system according to claim 21 further comprising: a controller coupled to the at least two electrodes adapted to examine triggering information validity and, for a valid condition, activating delivery of a pacing stimulation pulse following a predetermined delay of zero or more milliseconds. 23. The system according to claim 21 further comprising: a controller coupled to the at least two electrodes adapted to examine output pulse duration from the co-implanted pulse generator for usage as a signature for determining triggering information validity and, for a signature arriving within predetermined limits, activating delivery of a pacing pulse following a predetermined delay of zero or more milliseconds, the predetermined delay being determined from a method in a group consisting of preset at manufacture, programmed via an external programmer, and adaptively monitoring and conforming to duration of a triggering signal. 24. The system according to claim 21 further comprising: a controller coupled to the at least two electrodes adapted to examine output pulse duration, amplitude, and rate from the co-implanted pulse generator for usage as a signature for determining triggering information validity and, for a signature arriving within predetermined limits, activating delivery of a pacing pulse following a predetermined delay of zero or more milliseconds. 25. The system according to claim 21 further comprising: a controller coupled to the at least two electrodes adapted to trigger delivery of an atrial pacing pulse in response to sensing of an atrial heartbeat in sinus rhythm and in response to detection of sinus rhythm below a selected rate for atrial triggered pacing. 26. The system according to claim 21 further comprising: a controller coupled to the at least two electrodes adapted to limit synchronous pacing pulse delivery rate to a selected maximum rate. 27. The system according to claim 18 further comprising: a plurality of leadless cardiac pacemakers configured for implantation in electrical contact with at least one cardiac chamber and distributed epicardially, the leadless cardiac pacemaker plurality adapted to be timed from an initial triggering pulse for generating simultaneous pulses for defibrillation or cardioversion therapy. 28. The system according to claim 1 wherein the pacing pulse generator is further configured to generate stimulation pulses encoding information for transmission as communication signals. 29. The system according to claim 1 wherein the pacing pulse generator is configured to encode programmable parameter setting information on the pulses.
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