초록 ▼

Devices and methods for extraction, identification, authentication, and quantification of one or more covert markers in a material are disclosed. An extraction system includes a first plug flow mixer for mixing a first fluid bearing a marker and transfer agent into a plug flow. The mixing and flowin

Devices and methods for extraction, identification, authentication, and quantification of one or more covert markers in a material are disclosed. An extraction system includes a first plug flow mixer for mixing a first fluid bearing a marker and transfer agent into a plug flow. The mixing and flowing of the immiscible liquids causes transfer of the marker from the fluid to the transfer agent. A splitter having filters of different surface energies separates the two immiscible liquids, the transfer agent bearing the marker. A second plug flow can be used to transfer the marker to a second transfer agent. The transferred marker is detected to authenticate the original fluid. The marker can be further isolated, activated, or reacted to perform detection, identification or authentication. With the device, a number of independent processing and analytic steps are combined onto a single, portable unit.

대표청구항 ▼

1. A system comprising: a plug flow mixer having a first fluid inlet receiving a fluid containing a marker, a second fluid inlet receiving a transfer agent, and an outlet conveying a plug flow of the fluid and transfer agent, wherein the plug flow mixer and the outlet are configured to transfer the

1. A system comprising: a plug flow mixer having a first fluid inlet receiving a fluid containing a marker, a second fluid inlet receiving a transfer agent, and an outlet conveying a plug flow of the fluid and transfer agent, wherein the plug flow mixer and the outlet are configured to transfer the marker from the fluid to the transfer agent; anda splitter having first and second filters separating from the plug flow, the fluid and the transfer agent bearing the marker. 2. The system of claim 1, further comprising a second plug flow mixer having an inlet receiving the first transfer agent bearing the marker, and a second inlet receiving a second transfer agent, and an outlet conveying a plug flow of the first and second transfer agents, wherein the mixer and outlet are configured to transfer the marker from the first transfer agent to the second transfer agent. 3. The system of claim 1, further comprising a detector in communication with an outlet of the splitter detecting the presence of the marker in the transfer agent. 4. The system of claim 1, wherein the splitter comprises a first filter and a second filter, the filters configured respectively to selectively pass one of the fluid and the transfer agent and to substantially block the other of the fluid and the transfer agent. 5. The system of claim 4, wherein the first filter is a lipophobic membrane and the second filter is a hydrophobic membrane. 6. The system of claim 5, wherein the first and second filters are spaced apart a distance approximately equal to a diameter of the outlet of the plug flow mixer, whereby plugs conveyed from the outlet are in contact with both the first and the second filter within the splitter. 7. The system of claim 4, wherein the splitter further comprises: a splitter inlet receiving a plug flow into a filter chamber defined in part by the first and second filters;a first outlet chamber and first outlet conveying the fluid passed by the first filter;a second outlet chamber and second outlet conveying the transfer agent passed by the second filter. 8. The system of claim 7, wherein one of the first and second outlet chambers is positioned diametrically opposite the splitter inlet. 9. The system of claim 7, wherein one of the first and second outlet chambers is tapered in height or width between the inlet and the outlet. 10. The system of claim 7, wherein the filter channel and first and second outlet channels are configured as an ellipse between the splitter inlet and the outlet chamber outlets. 11. The system of claim 7, wherein the splitter inlet has a diameter of between 5-10 mm, a height of between 200-400 μm and the outlet chambers each have a diameter of between 5-10 mm and a height of between 100-400 μm. 12. The system of claim 7, wherein one of the first and second outlet chambers defines a network of channels conveying one of the fluid and the transfer agent to a respective one of the chamber outlets. 13. The system of claim 1, wherein the fluid comprises a fuel, a lubricant, spirits, or a liquid pharmaceutical. 14. The system of claim 1, wherein plug flow mixer is in a form of a T-junction or Y-junction. 15. A system comprising: a plug flow mixer having a first fluid inlet for receiving a fluid containing a marker, a second fluid inlet for receiving a transfer agent and an outlet for conveying a plug flow of the fluid and transfer agent, wherein the plug flow mixer and the outlet are configured to permit transfer of the marker from the fluid to the transfer agent; anda splitter having first and second filters for separating from the plug flow, the fluid and the transfer agent bearing the marker. 16. The system of claim 15, further comprising a second plug flow mixer having an inlet for receiving the first transfer agent bearing the marker and a second inlet for receiving a second transfer agent, and an outlet for conveying a plug flow of the first and second transfer agents, wherein the mixer and outlet are configured to permit transfer of the marker from the first transfer agent to the second transfer agent. 17. The system of claim 15, wherein the splitter comprises a first filter and a second filter, the filters configured respectively to selectively pass one of the fluid and the transfer agent and to substantially block the other of the fluid and the transfer agent. 18. The system of claim 17, wherein the first and second filters are spaced apart a distance approximately equal to a diameter of the outlet of the plug flow mixer, whereby plugs conveyed from the outlet are in contact with both the first and the second filter within the splitter. 19. The system of claim 17, wherein the splitter further comprises: a splitter inlet for receiving a plug flow into a filter chamber defined in part by the first and second filters;a first outlet chamber and first outlet for conveying the fluid passed by the first filter;a second outlet chamber and second outlet for conveying the transfer agent passed by the second filter. 20. The system of claim 19, wherein one of the first and second outlet chambers is positioned diametrically opposite the splitter inlet. 21. The system of claim 19, wherein one of the first and second outlet chambers is tapered in height or width between the inlet and the outlet. 22. The system of claim 19, wherein the filter channel and first and second outlet channels are configured as an ellipse between the splitter inlet and the outlet chamber outlets. 23. The system of claim 19, wherein the inlet chamber has a diameter of between 5-10 mm, a height of between 200-400 μm and the outlet chambers each have a diameter of between 5-10 mm and a height of between 100- 400 μm. 24. The system of claim 15, wherein the fluid comprises a fuel, a lubricant, spirits, or a liquid pharmaceutical.