IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0646801
(2003-08-25)
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등록번호 |
US-8361091
(2013-01-29)
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발명자
/ 주소 |
- Schein, Douglas A.
- Wright, David W.
- Sirianne, Raymond
- Palermo, Philip D.
- Kroll, Russell J.
- Brassil, John M.
|
출원인 / 주소 |
- Organ Recovery Systems, Inc.
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인용정보 |
피인용 횟수 :
4 인용 특허 :
41 |
초록
▼
A cannula connects an organ with a perfusion system that monitors, treats, sustains and/or restores the viability of the organ and/or that transports and/or stores the organ. At least part of a cannula may be made of a soft elastomer to help avoid damage to the organ. In embodiments, the cannula inc
A cannula connects an organ with a perfusion system that monitors, treats, sustains and/or restores the viability of the organ and/or that transports and/or stores the organ. At least part of a cannula may be made of a soft elastomer to help avoid damage to the organ. In embodiments, the cannula includes a top portion, a bottom portion, a sealing ring and two compression straps. In embodiments, the cannula includes a top portion and a flexible bottom portion that may be attached to the top portion. In embodiments, part of the cannula is inserted directly into an artery and a suture is used to tie the artery in place. Also, the cannula may include an attachment feature that can be used to connect the cannula to an organ platform or chair. Various features of the cannula may allow a visual check for and venting of air bubbles in the cannula.
대표청구항
▼
1. A cannula for connecting an organ to an external fluid flow system, the cannula comprising: a first portion;a second portion,a pre-positioning structure formed on the first portion;a complementary pre-positioning structure formed on the second portion. the pre-positioning structure and the comple
1. A cannula for connecting an organ to an external fluid flow system, the cannula comprising: a first portion;a second portion,a pre-positioning structure formed on the first portion;a complementary pre-positioning structure formed on the second portion. the pre-positioning structure and the complementary pre-positioning structure arranged to engage each other while permitting relative movement of the first and second portions, wherein:a chamber is formed when the first and second portions are brought together;a first fitting is disposed on one of the first and the second portions, the first fitting being in fluid communication with the chamber;the second portion has a hole, the hole being in fluid communication with the chamber and being adapted to receive a section of tissue of the organ;at least one sealing surface is adapted to secure the section of tissue by pressure applied to the section of secured tissue between the first and second portions when the first and second portions are brought together;at least one of the first fitting and the hole is adapted to allow fluid flow from the external fluid flow system into the section of tissue, andthe relative movement permitted by the engagement of the pre-positioning structure and the complementary pre-positioning structure allows the first portion and the second portion to be positioned relative to each other such that a first sealing surface on the first portion is parallel to a second sealing surface on the second portion when the first sealing surface and the second sealing surface are spaced apart and allows the first and second portions to be brought together, while maintaining the first sealing surface parallel to the second sealing surface, to secure the section of tissue. 2. The cannula of claim 1, wherein the first fitting and the hole are configured such that fluid flow through the first fitting is substantially perpendicular to fluid flow through the hole. 3. The cannula of claim 1, wherein at least a portion of at least one of the first and second portions that forms part of the chamber is one of a transparent material and a translucent material. 4. The cannula of claim 1, further comprising: at least one fixing member on one of the first and second portions; andat least one compression strap arranged to wrap around at least part of the first portion and at least part of the second portion and to engage the fixing member so that the first and second portions are brought together. 5. The cannula of claim 4, further comprising a sealing ring disposed between the first and second portions, the compression strap extending from the sealing ring. 6. The cannula of claim 5, the sealing ring being integral with the compression strap. 7. The cannula of claim 4, further comprising: at least one engagement member on one of the first and second portions; anda complementary engagement member at a free end of the compression strap;wherein the engagement member is arranged to engage the complementary engagement member while the compression strap is wrapped around at least part of the first portion and at least part of the second portion and engages the fixing member so that the first and second portions are brought together. 8. The cannula of claim 1 wherein the relative movement permitted by the engagement of the pre-positioning structure and the complementary pre-positioning structure comprises a pivoting movement that allows the first portion and the second portion to be positioned relative to each other such that the first sealing surface is parallel to the second sealing surface. 9. The cannula of claim 1, wherein the relative movement permitted by the engagement of the pre-positioning structure and the complementary pre-positioning structure comprises a linear movement that allows the first and second portions to be brought together, while maintaining the first sealing surface parallel to the second sealing surface. 10. The cannula of claim 1, wherein the relative movement permitted by the engagement of the pre-positioning structure and the complementary pre-positioning structure comprises a pivoting movement that allows the first portion and the second portion to be positioned relative to each other such that the first sealing surface is parallel to the second sealing surface and a linear movement that allows the first and second portions to be brought together, while maintaining the first sealing surface parallel to the second sealing surface. 11. The cannula of claim 1, wherein a flange extends from an outer surface of the second portion. 12. The cannula of claim 1, further comprising: at least one sealing ring disposed between the top and bottom portions. 13. The cannula of claim 12, wherein the sealing ring comprises an elastomeric material. 14. The cannula of claim 12, wherein the first portion has a first sealing surface, the second portion has a second sealing surface, and the sealing ring has a shape complementary to a shape of at least one of the first and second sealing surfaces. 15. The cannula of claim 14, wherein at least one of the first and second sealing surfaces comprises at least one of ribs, ridges, cuts and protrusions and the sealing ring comprises a plurality of complementary details corresponding to the at least one of ribs, ridges, cuts and protrusions. 16. The cannula of claim 1, wherein the first portion has a first sealing surface, the second portion has a second sealing surface, and at least one of the first and second sealing surfaces comprises an elastomeric material. 17. The cannula of claim 16, wherein at least one of the first and second sealing surfaces comprises at least one of ribs, ridges, cuts and protrusions. 18. The cannula of claim 1, the at least one sealing surface and one of the first and second portions being disposed on opposite sides of the section of secured tissue. 19. The cannula of claim 18, the at least one sealing surface being unitary with only the other of the first and second portions. 20. The cannula of claim 1, the at least one sealing surface being planar and disposed such that the section of secured tissue contacts and extends along the planar surface. 21. The cannula of claim 1, an upper portion of the first portion opposite of the hole is designed to collect gas separate from a fluid flow through the first fitting, the chamber and the hole. 22. A cannula for connecting an organ to an external fluid flow system, the cannula comprising: a first portion; anda second portion, wherein:a chamber is formed when the first and second portions are brought together;a first fitting is disposed on one of the first and the second portions. the first fitting being in fluid communication with the chamber,the second portion has a hole, the hole being in fluid communication with the chamber and being adapted to receive a section of tissue of the organ;at least one sealing surface is adapted to secure the section of tissue by pressure applied to the section of secured tissue between the first and second portions when the first and second portions are brought together; andat least one of the first fitting and the hole is adapted to allow fluid flow from the external fluid flow system into the section of tissue,wherein the chamber is designed to collect and trap gas separate from a fluid flow through the first fitting, the chamber and the hole. 23. The cannula of claim 1, further comprising a second fitting formed on one of the first and second portions, the second fitting being in fluid communication with the chamber that is formed when the first and second portions are brought together. 24. The cannula of claim 23, wherein the first fitting and the hole are configured such that fluid flow through the second fitting is substantially perpendicular to fluid flow through the hole. 25. The cannula of claim 23, wherein the second fitting comprises at least one of a vent and a valve. 26. The cannula of claim 23, wherein the second fitting is adapted to connect to a first fitting of a second cannula. 27. A method for connecting an organ to a fluid flow system, comprising: providing the cannula of claim 1; andsecuring a section of tissue of an organ between the first and second portions of the cannula. 28. The method of claim 27, further comprising: connecting the first fitting to a fluid flow system; andvisually checking for gas in the cannula after connecting the first fitting to a fluid flow system. 29. The method of claim 27, further comprising: connecting the first fitting to a fluid flow system; andopening a second fitting, in communication with the chamber formed when the first and second portions are brought together, to allow gas in the cannula to be removed from a flow of liquid between the fluid flow system and the organ. 30. The method of claim 27, further comprising: connecting the first fitting to a fluid flow system; andconnecting a second fitting of the cannula to a first fitting of another cannula to allow a flow of liquid between the fluid flow system and both cannulas. 31. The method of claim 27, further comprising: providing a cannula mount adapted to engage and support the cannula; andengaging the cannula with the cannula mount after securing the section of tissue. 32. The method according to claim 31, further comprising adjusting a position of the cannula relative to the cannula mount after engaging the cannula with the cannula mount. 33. The method of claim 32, wherein adjusting the position of the cannula comprises rotating the cannula relative to the cannula mount. 34. The method according to claim 31, further comprising: providing a platform adapted to support the organ and to engage and support the cannula mount;engaging the cannula mount with the platform after securing the section of tissue; andplacing the organ on the platform. 35. The method of claim 34, further comprising adjusting a position of the cannula mount relative to the platform after engaging the cannula mount with the platform. 36. The method of claim 35, wherein adjusting the position of the cannula mount comprises adjusting a distance of the cannula relative to a portion of the platform that supports the organ. 37. A method for connecting an organ to a fluid flow system, comprising: providing the cannula of claim 17; andsecuring a section of tissue of an organ between the first and second portions of the cannula. 38. The method of claim 37, further comprising: connecting the first fitting to a fluid flow system; andvisually checking for gas in the cannula after connecting the first fitting to a fluid flow system. 39. The method of claim 37, further comprising: connecting the first fitting to a fluid flow system; andopening a second fitting on the first portion to allow gas in the cannula to be removed from a flow of liquid between the fluid flow system and the organ. 40. The method of claim 37, further comprising: connecting the first fitting to a fluid flow system; andconnecting a second fitting of the cannula to a first fitting of another cannula to allow a flow of liquid between the fluid flow system and both cannulas. 41. The method of claim 37, further comprising: providing a cannula mount adapted to engage and support the cannula; andengaging the cannula with the cannula mount after securing the section of tissue. 42. The method according to claim 41, further comprising adjusting a position of the cannula relative to the cannula mount after engaging the cannula with the cannula mount. 43. The method of claim 42, wherein adjusting the position of the cannula comprises rotating the cannula relative to the cannula mount. 44. The method according to claim 41, further comprising: providing a platform adapted to support the organ and to engage and support the cannula mount;engaging the cannula mount with the platform after securing the section of tissue; andplacing the organ on the platform. 45. The method of claim 44, further comprising adjusting a position of the cannula mount relative to the platform after engaging the cannula mount with the platform. 46. The method of claim 45, wherein adjusting the position of the cannula mount comprises adjusting a distance of the cannula relative to a portion of the platform that supports the organ. 47. A cannula for connecting an organ to an external fluid flow system, the cannula comprising: a first portion;a second portion; anda connection between the first portion and the second portion, wherein:a chamber is formed when the first and second portions are brought together;a first fitting is disposed on one of the first and the second portions, the first fitting being in fluid communication with the chamber;the second portion has a hole, the hole being in fluid communication with the chamber and being adapted to receive a section of tissue of the organ;at least one sealing surface is adapted to secure the section of tissue by pressure applied to the section of secured tissue between the first and second portions when the first and second portions are brought together;at least one of the first fitting and the hole is adapted to allow fluid flow from the external fluid flow system into the section of tissue; andthe connection allows both relative linear motion and relative rotational motion between the first portion and the second portion. 48. A cannula for connecting an organ to an external fluid flow system, the cannula comprising: a first portion;a second portion, anda connection between the first portion and the second portion, wherein:a chamber is formed when the first and second portions are brought together;a first fitting is disposed on one of the first and the second portions, the first fitting being in fluid communication with the chamber;the second portion has a hole, the hole being in fluid communication with the chamber and being adapted to receive a section of tissue of the organ;at least one sealing surface is adapted to secure the section of tissue by pressure applied to the section of secured tissue between the first and second portions when the first and second portions are brought together;at least one of the first fitting and the hole is adapted to allow fluid flow from the external fluid flow system into the section of tissue; andthe connection allows relative linear motion between the first portion and the second portion.
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