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| 국가/구분 | United States(US) Patent 등록 |
|---|---|
| 국제특허분류(IPC7판) |
|
| 출원번호 | US-0238497 (2005-09-28) |
| 등록번호 | US-8372094 (2013-02-12) |
| 발명자 / 주소 |
|
| 출원인 / 주소 |
|
| 인용정보 | 피인용 횟수 : 439 인용 특허 : 92 |
A seal element for sealing between tissue lumens includes a first material for allowing tissue ingrowth and a second sealant material.
1. An assembly for disposing a seal element between tissue lumens comprising: a circular surgical stapling device comprising an anvil assembly and a tubular body portion wherein the anvil assembly comprises an anvil member and a first shaft and the tubular body portion comprises a plurality of surgi
1. An assembly for disposing a seal element between tissue lumens comprising: a circular surgical stapling device comprising an anvil assembly and a tubular body portion wherein the anvil assembly comprises an anvil member and a first shaft and the tubular body portion comprises a plurality of surgical staples in a circular configuration and a second shaft disposed inwardly of the surgical staples, the first shaft being attachable to the second shaft; anda seal element disposable between tissue lumens, the seal element comprising a first material and a second material wherein the first material promotes tissue ingrowth and the second material comprises a sealant. 2. The assembly of claim 1 wherein the first material is a porous material. 3. The assembly of claim 2 wherein the first material is selected from the group consisting of a foam, a mesh, a non-woven structure, a perforated sheet and combinations thereof. 4. The assembly of claim 2 wherein the first material is selected from the group consisting of glycolide, lactide, caprolactone, trimethylene carbonate, dioxanone, polyalkylene oxides, and combinations thereof. 5. The assembly of claim 2 wherein the first material comprises a porous material having pores ranging in size from about 50 μm to about 200 μm. 6. The assembly of claim 2 wherein the first material has a thickness ranging from about 0.010 inches to about 0.020 inches. 7. The assembly of claim 2 wherein the second material is compressible. 8. The assembly of claim 2 wherein the second material is expandable. 9. The assembly of claim 2 wherein the second material is a hydrophilic material. 10. The assembly of claim 2 wherein the second material is derived from a monomer selected from the group consisting of methacrylic acid, acrylic acid, n-vinyl pyrrolidone, potassium sulfopropyl acrylate, potassium sulfopropyl methacrylate, acrylamide, dimethylacrylamide, 2-methacryloyloxyethyl phosphorylcholine, hydroxethylmethacrylate, 2-hydroxyethyl methacrylate and combinations thereof. 11. The assembly of claim 2 wherein the second material is poly(2-hydroxyethyl methacrylate). 12. The assembly of claim 2 wherein the second material comprises a surface having a pattern formed thereon. 13. The assembly of claim 2 wherein at least one of the first or second materials further comprises at least one medically useful substance. 14. The assembly of claim 13 wherein the at least one medically useful substance is selected from the group consisting of drugs, enzymes, growth factors, peptides, proteins, dyes, diagnostic agents, hemostasis agents, antimicrobials, antibiotics, anti-fungals, anti-virals, monoclonal antibodies, polyclonal antibodies, antimicrobial proteins/peptides, enzymes, gene therapy, viral particles, chemotherapeutics, anti-inflammatories, NSAIDS, steroids, telomerase inhibitors, growth factors, extracellular matrix molecules, cell adhesion molecules, polysaccharides and combinations thereof. 15. The assembly of claim 2 further comprising a generally centrally located aperture. 16. A method of disposing a seal element between adjacent tubular tissues to be joined, the method comprising: providing a circular surgical anastomosis device, the circular surgical anastomosis device including:an anvil assembly having an anvil member and a first shaft; anda tubular body portion having an annular knife operatively disposed therein and a second shaft disposed radially inward of the annular knife, the first shaft of the anvil assembly being selectively attachable to the second shaft of the tubular body;inserting the anvil assembly into a first tubular tissue;inserting the tubular body portion into a second tubular tissue;disposing the seal element between the first tubular tissue and the second tubular tissue, the seal element comprising a first material and a second material wherein the first material promotes tissue ingrowth and the second material comprises a sealant;approximating the anvil assembly and tubular body portion with one another so that an end portion of the first tubular tissue, the seal element, and an end portion of the second tubular tissue are disposed between the anvil member and the tubular body portion, the seal element being disposed between the first tubular tissue and the second tubular tissue;firing the surgical anastomosis device to sever the portions of the first and second tubular tissues disposed radially inward of the annular knife, and to touch the portions of the first and second tubular tissues radially outward of the annular knife against the seal element to thereby secure the seal element between the first and second tubular tissues.
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