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Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0621728 (2007-01-10) |
등록번호 | US-8377016 (2013-02-19) |
발명자 / 주소 |
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출원인 / 주소 |
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인용정보 | 피인용 횟수 : 20 인용 특허 : 349 |
A tissue treatment apparatus and method are provided for treating tissue by the application of the time-varying sub-atmospheric pressure. The apparatus includes a cover adapted to cover a wound and adapted to maintain sub-atmospheric pressure the site of the wound. The apparatus further includes a s
A tissue treatment apparatus and method are provided for treating tissue by the application of the time-varying sub-atmospheric pressure. The apparatus includes a cover adapted to cover a wound and adapted to maintain sub-atmospheric pressure the site of the wound. The apparatus further includes a source of suction configured to generate a time-varying sub-atmospheric pressure having a periodic waveform comprising a gradual change in pressure. The suction source cooperates with the cover to supply the time-varying sub-atmospheric pressure under the cover to the wound. The time-varying sub-atmospheric pressure may vary between a first pressure value below the inherent tissue tension of the wound tissue and a second pressure value above the inherent tissue tension of the wound tissue.
1. An apparatus for administering sub-atmospheric pressure to a wound, comprising: (a) a cover adapted to cover a wound and adapted to maintain sub-atmospheric pressure at the site of the wound;(b) a seal configured to seal the cover to tissue surrounding the wound; and(c) a source of suction config
1. An apparatus for administering sub-atmospheric pressure to a wound, comprising: (a) a cover adapted to cover a wound and adapted to maintain sub-atmospheric pressure at the site of the wound;(b) a seal configured to seal the cover to tissue surrounding the wound; and(c) a source of suction configured to generate a time-varying sub-atmospheric pressure having a periodic waveform comprising a gradual change in pressure, the suction source cooperating with the cover to supply the time-varying sub-atmospheric pressure under the cover to the wound,wherein the source of suction is configured to generate a triangular-waveform variation in pressure between a first pressure value below atmospheric pressure and a second pressure value below atmospheric pressure. 2. An apparatus for administering sub-atmospheric pressure to a wound, comprising: (a) a cover adapted to cover a wound and adapted to maintain sub-atmospheric pressure at the site of the wound;(b) a seal configured to seal the cover to tissue surrounding the wound; and(c) a source of suction configured to generate a time-varying sub-atmospheric pressure having a periodic waveform comprising a gradual change in pressure, the suction source cooperating with the cover to supply the time-varying sub-atmospheric pressure under the cover to the wound,wherein the source of suction is configured to generate a sinusoidal-waveform variation in pressure between a first pressure value below atmospheric pressure and a second pressure value below atmospheric pressure. 3. The apparatus of claim 2, wherein the first pressure value is 25 mm Hg below atmospheric pressure and the second pressure value is 100 mm Hg below atmospheric pressure. 4. The apparatus of claim 2, wherein the first pressure value is below the inherent tissue tension of the wound tissue and the second pressure value is above the inherent tissue tension of the wound tissue. 5. The apparatus of claim 1, wherein the first pressure value is 25 mm Hg below atmospheric pressure and the second pressure value is 100 mm Hg below atmospheric pressure. 6. The apparatus of claim 1, wherein the first pressure value is below the inherent tissue tension of the wound tissue and the second pressure value is above the inherent tissue tension of the wound tissue. 7. An apparatus for administering sub-atmospheric pressure to a wound, comprising: (a) a cover adapted to cover a wound and adapted to maintain sub-atmospheric pressure at the site of the wound;(b) a seal configured to seal the cover to tissue surrounding the wound; and(c) a source of suction configured to generate a time-varying sub-atmospheric pressure having a periodic waveform comprising a gradual change in pressure, the suction source cooperating with the cover to supply the time-varying sub-atmospheric pressure under the cover to the wound,wherein the source of suction is configured to generate a sawtooth-waveform variation in pressure between a first pressure value below atmospheric pressure and a second pressure value below atmospheric pressure. 8. The apparatus of claim 7, wherein the first pressure value is 25 mm Hg below atmospheric pressure and the second pressure value is 100 mm Hg below atmospheric pressure. 9. The apparatus of claim 7, wherein the first pressure value is below the inherent tissue tension of the wound tissue and the second pressure value is above the inherent tissue tension of the wound tissue. 10. The apparatus of claim 1, wherein the source of suction comprises a vacuum pump. 11. The apparatus of claim 1, wherein the cover comprises a flexible sheet. 12. The apparatus of claim 11, wherein the seal includes an adhesive on a sheet surface facing the wound to attach and seal the sheet to tissue surrounding the wound. 13. The apparatus of claim 11, comprising a screen for placement at the wound between the cover and the wound. 14. The apparatus of claim 1, comprising a screen for placement at the wound between the cover and the wound. 15. The apparatus of claim 14, wherein the screen comprises open-cell foam. 16. The apparatus of claim 14, wherein the screen comprises a synthetic polymer material. 17. The apparatus of claim 14, wherein the screen comprises a non-adherent material. 18. The apparatus of claim 14, wherein the screen comprises a polymer mesh. 19. The apparatus of claim 18, wherein the screen comprises a synthetic polymer material. 20. The apparatus of claim 19, wherein the screen comprises an ointment. 21. The apparatus of claim 14, wherein the screen is configured to promote the formation of tissue of the type with which the screen is in contact. 22. The apparatus of claim 14, wherein the screen is configured to promote the formation of granulation tissue. 23. The apparatus of claim 14, wherein the screen is configured to promote tissue growth therein. 24. The apparatus of claim 14, wherein the screen is configured to deter tissue growth therein. 25. The apparatus of claim 14, wherein the screen comprises a bio-absorbable material. 26. The apparatus of claim 1, comprising a port at the cover configured to deliver the sub-atmospheric pressure under the cover. 27. The apparatus of claim 26, wherein port comprises a tube in gaseous communication with the source of suction. 28. The apparatus of claim 27, wherein the tube extends under an edge of the cover. 29. An apparatus for administering sub-atmospheric pressure to a wound, comprising: (a) a self-adhesive cover adapted to cover and form a seal about a wound to maintain sub-atmospheric pressure at the site of the wound;(b) port at the cover configured to deliver the sub-atmospheric pressure under the cover; and(c) a source of suction for gaseous communication with the port, the source of suction configured to generate a sinusoidally varying sub-atmospheric pressure under the cover to the wound,wherein the source of suction is configured to generate a sinusoidal-waveform variation in pressure between a first pressure value below atmospheric pressure and a second pressure value below atmospheric pressure under the cover of the wound. 30. The apparatus of claim 29, wherein sinusoidally varying sub-atmospheric pressure has a minimum value of 25 mm Hg below atmospheric pressure and a maximum value of 100 mm Hg below atmospheric pressure. 31. The apparatus of claim 29, wherein the sub-atmospheric pressure varies between a first pressure value below the inherent tissue tension of the wound tissue and a second pressure value above the inherent tissue tension of the wound tissue. 32. The apparatus of claim 29, wherein the source of suction comprises a vacuum pump. 33. The apparatus of claim 29, wherein the cover comprises a flexible sheet. 34. The apparatus of claim 33, comprising a screen for placement at the wound between the cover and the wound. 35. The apparatus of claim 29, comprising a screen for placement at the wound between the cover and the wound. 36. The apparatus of claim 35, wherein the screen comprises open-cell foam. 37. The apparatus of claim 35, wherein the screen comprises a synthetic polymer material. 38. The apparatus of claim 35, wherein the screen comprises a non-adherent material. 39. The apparatus of claim 35, wherein the screen comprises a polymer mesh. 40. The apparatus of claim 39, wherein the screen comprises a synthetic polymer material. 41. The apparatus of claim 40, wherein the screen comprises an ointment. 42. The apparatus of claim 35, wherein the screen is configured to promote the formation of tissue of the type with which the screen is in contact. 43. The apparatus of claim 35, wherein the screen is configured to promote the formation of granulation tissue. 44. The apparatus of claim 35, wherein the screen is configured to promote tissue growth therein. 45. The apparatus of claim 35, wherein the screen is configured to deter tissue growth therein. 46. The apparatus of claim 35, wherein the screen comprises a bio-absorbable material. 47. The apparatus of claim 29, wherein the port comprises a tube in gaseous communication with the source of suction. 48. The apparatus of claim 47, wherein the tube extends under an edge of the cover. 49. An apparatus for administering sub-atmospheric pressure to a wound, comprising: (a) a cover adapted to cover a wound to provide an enclosure above the wound in which sub-atmospheric pressure may be maintained;(b) a screen configured to overlie the wound under the cover; and(c) a vacuum means in gaseous communication with the cover to supply sub-atmospheric pressure within the enclosure, the vacuum means configured to generate a cyclically-varying sub-atmospheric pressure comprising a gradual change in pressure,wherein the vacuum means is configured to generate a sinusoidal-waveform variation in pressure between a first pressure value below atmospheric pressure and a second pressure value below atmospheric pressure. 50. The apparatus of claim 1, wherein the first pressure value is 25 mm Hg below atmospheric pressure and the second pressure value is 100 mm Hg below atmospheric pressure. 51. The apparatus of claim 1, wherein the first pressure value is below the inherent tissue tension of the wound tissue and the second pressure value is above the inherent tissue tension of the wound tissue. 52. An apparatus for administering sub-atmospheric pressure to a wound, comprising: (a) a cover adapted to cover a wound to provide an enclosure above the wound in which sub-atmospheric pressure may be maintained;(b) a screen configured to overlie the wound under the cover; and(c) a vacuum means in gaseous communication with the cover to supply sub-atmospheric pressure within the enclosure, the vacuum means configured to generate a cyclically-varying sub-atmospheric pressure comprising a gradual change in pressure,wherein the vacuum means is configured to generate a triangular-waveform variation in pressure between a first pressure value below atmospheric pressure and a second pressure value below atmospheric pressure. 53. The apparatus of claim 52, wherein the first pressure value is 25 mm Hg below atmospheric pressure and the second pressure value is 100 mm Hg below atmospheric pressure. 54. The apparatus of claim 52, wherein the first pressure value is below the inherent tissue tension of the wound tissue and the second pressure value is above the inherent tissue tension of the wound tissue. 55. An apparatus for administering sub-atmospheric pressure to a wound, comprising: (a) a cover adapted to cover a wound to provide an enclosure above the wound in which sub-atmospheric pressure may be maintained;(b) a screen configured to overlie the wound under the cover; and(c) a vacuum means in gaseous communication with the cover to supply sub-atmospheric pressure within the enclosure, the vacuum means configured to generate a cyclically-varying sub-atmospheric pressure comprising a gradual change in pressure,wherein the vacuum means is configured to generate a sawtooth-waveform variation in pressure between a first pressure value below atmospheric pressure and a second pressure value below atmospheric pressure. 56. The apparatus of claim 55, wherein the first pressure value is 25 mm Hg below atmospheric pressure and the second pressure value is 100 mm Hg below atmospheric pressure. 57. The apparatus of claim 55, wherein the first pressure value is below the inherent tissue tension of the wound tissue and the second pressure value is above the inherent tissue tension of the wound tissue. 58. The apparatus of claim 49, wherein the vacuum means comprises a vacuum pump. 59. The apparatus of claim 49, wherein the cover comprises a flexible self-adhesive sheet for sealing to tissue about the wound. 60. The apparatus of claim 49, wherein the screen comprises open-cell foam. 61. The apparatus of claim 49, wherein the screen comprises a synthetic polymer material. 62. The apparatus of claim 49, wherein the screen comprises a non-adherent material. 63. The apparatus of claim 49, wherein the screen comprises a polymer mesh. 64. The apparatus of claim 63, wherein the screen comprises a synthetic polymer material. 65. The apparatus of claim 64, wherein the screen comprises an ointment. 66. The apparatus of claim 49, wherein the screen is configured to promote the formation of tissue of the type with which the screen is in contact. 67. The apparatus of claim 49, wherein the screen is configured to promote the formation of granulation tissue. 68. The apparatus of claim 49, wherein the screen is configured to promote tissue growth therein. 69. The apparatus of claim 49, wherein the screen is configured to deter tissue growth therein. 70. The apparatus of claim 49, wherein the screen comprises a bio-absorbable material. 71. The apparatus of claim 49, comprising a port at the cover configured to deliver the sub-atmospheric pressure under the cover. 72. The apparatus of claim 71, wherein the port comprises a tube in gaseous communication with the vacuum means. 73. The apparatus of claim 72, wherein the tube extends under an edge of the cover. 74. An apparatus for administering sub-atmospheric pressure to a wound, comprising: a) a cover adapted to cover a wound to provide an enclosure above the wound in which sub-atmospheric pressure may be maintained;(b) a port disposed at the cover configured to deliver the sub-atmospheric pressure under the cover; and(c) a vacuum means in gaseous communication with the port to supply sub-atmospheric pressure within the enclosure, the vacuum means configured to generate a cyclically-varying sub-atmospheric pressure comprising a gradual change in pressure over at least a portion of the cycle, the change ranging from first pressure value below the inherent tissue tension of the wound tissue to a second pressure value above the inherent tissue tension of the wound tissue,wherein the vacuum means is configured to generate a sawtooth-waveform variation in pressure between a first pressure value below atmospheric pressure and a second pressure value below atmospheric pressure. 75. An apparatus for administering sub-atmospheric pressure to a wound, comprising: a) a cover adapted to cover a wound to provide an enclosure above the wound in which sub-atmospheric pressure may be maintained;(b) a port disposed at the cover configured to deliver the sub-atmospheric pressure under the cover; and(c) a vacuum means in gaseous communication with the port to supply sub-atmospheric pressure within the enclosure, the vacuum means configured to generate a cyclically-varying sub-atmospheric pressure comprising a gradual change in pressure over at least a portion of the cycle, the change ranging from first pressure value below the inherent tissue tension of the wound tissue to a second pressure value above the inherent tissue tension of the wound tissue,wherein the vacuum means is configured to generate a sinusoidal-waveform variation in pressure between a first pressure value below atmospheric pressure and a second pressure value below atmospheric pressure. 76. The apparatus of claim 75, wherein the first pressure value is 25 mm Hg below atmospheric pressure and the second pressure value is 100 mm Hg below atmospheric pressure. 77. An apparatus for administering sub-atmospheric pressure to a wound, comprising: (a) a cover adapted to cover a wound to provide an enclosure above the wound in which sub-atmospheric pressure may be maintained;(b) a port disposed at the cover configured to deliver the sub-atmospheric pressure under the cover; and(c) a vacuum means in gaseous communication with the port to supply sub-atmospheric pressure within the enclosure, the vacuum means configured to generate a cyclically-varying sub-atmospheric pressure comprising a gradual change in pressure over at least a portion of the cycle, the change ranging from first pressure value below the inherent tissue tension of the wound tissue to a second pressure value above the inherent tissue tension of the wound tissue,wherein the vacuum means is configured to generate a triangular-waveform variation in pressure between a first pressure value below atmospheric pressure and a second pressure value below atmospheric pressure. 78. The apparatus of claim 77, wherein the first pressure value is 25 mm Hg below atmospheric pressure and the second pressure value is 100 mm Hg below atmospheric pressure. 79. The apparatus of claim 74, wherein the first pressure value is 25 mm Hg below atmospheric pressure and the second pressure value is 100 mm Hg below atmospheric pressure. 80. The apparatus of claim 74, wherein the vacuum means comprises a vacuum pump. 81. The apparatus of claim 74, wherein the cover comprises a flexible self-adhesive sheet for sealing to tissue about the wound. 82. The apparatus of claim 81, comprising a screen for placement at the wound between the cover and the wound. 83. The apparatus of claim 74, comprising a screen for placement at the wound between the cover and the wound. 84. The apparatus of claim 83, wherein the screen comprises open-cell foam. 85. The apparatus of claim 83, wherein the screen comprises a synthetic polymer material. 86. The apparatus of claim 83, wherein the screen comprises a non-adherent material. 87. The apparatus of claim 83, wherein the screen comprises a polymer mesh. 88. The apparatus of claim 87, wherein the screen comprises a synthetic polymer material. 89. The apparatus of claim 88, wherein the screen comprises an ointment. 90. The apparatus of claim 83, wherein the screen is configured to promote the formation of tissue of the type with which the screen is in contact. 91. The apparatus of claim 83, wherein the screen is configured to promote the formation of granulation tissue. 92. The apparatus of claim 83, wherein the screen is configured to promote tissue growth therein. 93. The apparatus of claim 83, wherein the screen is configured to deter tissue growth therein. 94. The apparatus of claim 83, wherein the screen comprises a bio-absorbable material. 95. The apparatus of claim 74, wherein the port comprises a tube in gaseous communication with the vacuum means. 96. The apparatus of claim 95, wherein the tube extends under an edge of the cover. 97. A method for administering sub-atmospheric pressure to a wound, comprising the steps of: (a) covering a wound with a wound cover configured to maintain sub-atmospheric pressure under the cover at the site of the wound;(b) sealing the cover to tissue surrounding the wound to provide an enclosure for maintaining sub-atmospheric pressure under the cover about the wound; and(c) applying time-varying sub-atmospheric pressure under the cover to the wound, the sub-atmospheric pressure having a periodic waveform comprising a gradual change in pressure,wherein the time-varying sub-atmospheric pressure comprises a sinusoidal-waveform variation in pressure that varies between a first pressure value below atmospheric pressure and a second pressure value below atmospheric pressure. 98. The method of claim 97, wherein the first pressure value is 25 mm Hg below atmospheric pressure and the second pressure value is 100 mm Hg below atmospheric pressure. 99. The method of claim 97, wherein the first pressure value is below the inherent tissue tension of the wound tissue and the second pressure value is above the inherent tissue tension of the wound tissue. 100. A method for administering sub-atmospheric pressure to a wound, comprising the steps of: (a) covering a wound with a wound cover configured to maintain sub-atmospheric pressure under the cover at the site of the wound;(b) sealing the cover to tissue surrounding the wound to provide an enclosure for maintaining sub-atmospheric pressure under the cover about the wound; and(c) applying time-varying sub-atmospheric pressure under the cover to the wound, the sub-atmospheric pressure having a periodic waveform comprising a gradual change in pressure,wherein the time-varying sub-atmospheric pressure comprises a triangular-waveform variation in pressure between a first pressure value below atmospheric pressure and a second pressure value below atmospheric pressure. 101. The method of claim 100, wherein the first pressure value is 25 mm Hg below atmospheric pressure and the second pressure value is 100 mm Hg below atmospheric pressure. 102. The method of claim 100, wherein the first pressure value is below the inherent tissue tension of the wound tissue and the second pressure value is above the inherent tissue tension of the wound tissue. 103. A method for administering sub-atmospheric pressure to a wound, comprising the steps of: (a) covering a wound with a wound cover configured to maintain sub-atmospheric pressure under the cover at the site of the wound;(b) sealing the cover to tissue surrounding the wound to provide an enclosure for maintaining sub-atmospheric pressure under the cover about the wound; and(c) applying time-varying sub-atmospheric pressure under the cover to the wound, the sub-atmospheric pressure having a periodic waveform comprising a gradual change in pressure,wherein the time-varying sub-atmospheric pressure comprises a sawtooth-waveform variation in pressure between a first pressure value below atmospheric pressure and a second pressure value below atmospheric pressure. 104. The method of claim 103, wherein the first pressure value is 25 mm Hg below atmospheric pressure and the second pressure value is 100 mm Hg below atmospheric pressure. 105. The method of claim 103, wherein the first pressure value is below the inherent tissue tension of the wound tissue and the second pressure value is above the inherent tissue tension of the wound tissue. 106. The method of claim 97, comprising placing a screen between the cover and the wound. 107. The method of claim 106, wherein the screen comprises open-cell foam. 108. The apparatus of claim 106, wherein the screen comprises a synthetic polymer material. 109. The method of claim 106, wherein the screen comprises a non-adherent material. 110. The apparatus of claim 106, wherein the screen comprises a polymer mesh. 111. The method of claim 110, wherein the screen comprises a synthetic polymer material. 112. The method of claim 111, wherein the screen comprises an ointment. 113. The method of claim 106, wherein the screen is configured to promote the formation of tissue of the type with which the screen is in contact. 114. The method of claim 106, wherein the screen is configured to promote the formation of granulation tissue. 115. The method of claim 106, wherein the screen is configured to promote tissue growth therein. 116. The apparatus of claim 106, wherein the screen is configured to deter tissue growth therein. 117. The method of claim 106, wherein the screen comprises a bio-absorbable material. 118. The apparatus according to any one of claims 1, 2, 7, 49, 52, 55, 74, 75, 77, 97, 100, or 103, wherein the gradual change in pressure comprises a digitized waveform.
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