[특허]Compositions of human lipids and methods of making and using same

[미국특허] Compositions of human lipids and methods of making and using same 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61K-039/00 A61K-047/00 A23D-007/00
출원번호	US-0518237 (2007-12-10)
등록번호	US-8377445 (2013-02-19)
국제출원번호	PCT/US2007/086973 (2007-12-10)
§371/§102 date	20100517 (20100517)
국제공개번호	WO2008/073888 (2008-06-19)
발명자 / 주소	Medo, Elena M. Eaker, Scott
출원인 / 주소	Prolacta Bioscience, Inc.
인용정보	피인용 횟수 : 0 인용 특허 : 44

초록

The disclosure features methods of making compositions that include a human lipid. The methods can include: obtaining whole human milk; separating the milk into a cream portion and a skim portion; processing the cream portion; and pasteurizing the processed cream portion.

대표청구항 ▼

1. A method of making a composition comprising a human lipid, the method comprising: (a) obtaining whole human milk;(b) separating the milk into a cream portion and a skim portion;(c) filtering the water out of the skim portion after step (b);(d) suspending the cream portion obtained in step (b) with the water obtained in step (c);(e) purifying the suspended cream portion obtained in step (d) to obtain a composition comprising a human lipid; and(f) parenterally administering the composition comprising a human lipid obtained in step (e) to a human subject. 2. The method of claim 1, further comprising (i) separating the cream portion obtained in step (b) into a second cream portion and a second skim portion; and(ii) in step (d) suspending both the cream portion and the second cream portion with the water obtained in step (c). 3. The method of claim 1, further comprising pasteurizing the composition comprising a human lipid after step (e). 4. The method of claim 1, wherein the purifying comprises diafiltration. 5. The method of claim 4, further comprising ultrafiltrating. 6. The method of claim 1, further comprising adding one or more constituents to the composition obtained in step (e) selected from the group consisting of: an emulsifier, a preservative, a diluent, and an osmolality modifier. 7. The method of claim 6, wherein the preservative is an antioxidant. 8. The method of claim 7, wherein the antioxidant is selected from the group consisting of: alpha-tocopherol, vitamin C, a carotenoid, and a retinoid. 9. The method of claim 6, wherein the osmolality modifier comprises glycerin. 10. The method of claim 1, further comprising, adding one or more constituents to the composition obtained in step (e) selected from the group consisting of: a vitamin, a mineral, and a carbohydrate. 11. The method of claim 1, wherein the administration is part of total parenteral nutritional administration. 12. The method of claim 1, wherein the subject is a premature infant. 13. The method of claim 1, wherein the subject has a nutritional disease or disorder.

이 특허에 인용된 특허 (44) 인용/피인용 타임라인 분석

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Lindquist, Anders, Method and apparatus for producing a sterile milk product.
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[미국특허] Compositions of human lipids and methods of making and using same 원문보기

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[미국특허] Compositions of human lipids and methods of making and using same 원문보기

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