Method and apparatus for controlling air pressure in an organ or tissue container
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A01N-001/00
A01N-001/02
B01F-003/04
출원번호
US-0654772
(2009-12-31)
등록번호
US-8389271
(2013-03-05)
발명자
/ 주소
Wright, David Walter
Schein, Douglas
Brassil, John
출원인 / 주소
Organ Recovery Systems, Inc.
인용정보
피인용 횟수 :
2인용 특허 :
95
초록▼
An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. The apparatus and methods include the organ cassette with one
An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. The apparatus and methods include the organ cassette with one or more openings configured to allow tubing to pass through the openings and be connected to the organ or tissue within the cassette, and including a pressure control device to allow pressure inside the portable housing to be varied.
대표청구항▼
1. An apparatus for holding an organ or tissue for at least one of perfusion, storage, diagnosis and transport of the organ, comprising: an organ cassette for holding the organ, the organ cassette including a wall that at least partially delimits a volume for holding the organ;a plurality of lids th
1. An apparatus for holding an organ or tissue for at least one of perfusion, storage, diagnosis and transport of the organ, comprising: an organ cassette for holding the organ, the organ cassette including a wall that at least partially delimits a volume for holding the organ;a plurality of lids that form at least one substantially airtight seal with the organ cassette, at least one lid being configured to open separately from at least one other of the plurality of lids; andan organ or tissue supporting surface configured to support the organ or tissue within the organ cassette while allowing effluent medical fluid to pass through the organ or tissue,wherein the organ cassette is configured to be received by at least one of a perfusion device, a portable perfusion device and a diagnostic device, andwherein at least two of the lids each includes at least one pressure control device that controls pressure within the organ cassette and the at least two lids are configured to each individually form a substantially airtight seal with the wall by coming into sealing contact with the wall. 2. The apparatus of claim 1, wherein the at least one pressure control device controls the pressure to be at a desired pressure. 3. The apparatus of claim 2, wherein the desired pressure is atmospheric pressure. 4. The apparatus of claim 1, wherein the organ cassette includes more than two pressure control devices. 5. The apparatus of claim 1, wherein the at least one pressure control device is at least one of a closable vent, a pressure control valve that controls the pressure within the organ cassette, and a membrane. 6. The apparatus of claim 5, wherein the at least one pressure control device includes a filter. 7. An apparatus for holding an organ or tissue for at least one of perfusion, storage, diagnosis and transport of the organ, comprising: an organ cassette for holding the organ, the organ cassette including a wall that at least partially delimits a volume for holding the organ;a plurality of lids that each form at least one substantially airtight seal with the organ cassette by coming into sealing contact with the wall, at least one lid being configured to open separately from at least one other of the plurality of lids; andan organ or tissue supporting surface configured to support the organ or tissue within the organ cassette while allowing effluent medical fluid to pass through the organ or tissue,wherein the organ cassette is configured to be received by at least one of a perfusion device, a portable perfusion device and a diagnostic device,wherein at least one of the lids includes at least one pressure control device that controls pressure within the organ cassette, andwherein the at least one pressure control device is a membrane. 8. The apparatus of claim 7, wherein one of the lids includes two pressure control devices. 9. The apparatus of claim 8, wherein the pressure control devices also include at least one of a closable vent and a pressure control valve. 10. The apparatus of claim 7, wherein at least two of the lids each includes a pressure control device. 11. The apparatus of claim 7, wherein the pressure control device controls pressure to be at a desired pressure. 12. The apparatus of claim 11, wherein the desired pressure is atmospheric pressure. 13. The apparatus of claim 7, wherein the membrane is a hydrophobic membrane. 14. The apparatus of claim 7, wherein pores of the membrane are small enough to prevent bacteria from entering the organ cassette. 15. The apparatus of claim 7, wherein the membrane is substantially impermeable to liquid. 16. A method of at least two of perfusion, storage, and transport of an organ or tissue, comprising: placing the organ or tissue in an organ cassette that is configured to be received by at least two of a perfusion device, a portable perfusion device and a diagnostic device, the organ cassette including: a wall that at least partially delimits a volume for holding the organ, anda plurality of lids that form at least one substantially airtight seal with the wall; andseparately opening or closing at least one of the plurality of lids without opening or closing at least one other of the plurality of lids,wherein at least two of the lids each includes at least one pressure control device that controls pressure within the organ cassette and the at least two lids are configured to each individually form a substantially airtight seal with the wall by coming into sealing contact with the wall. 17. The method of claim 16, wherein the at least one pressure control device controls pressure to be at a desired pressure. 18. The method of claim 17, wherein the desired pressure is atmospheric pressure. 19. The method of claim 16, wherein the pressure control device is at least one of a closable vent, a pressure control valve and a membrane that is substantially impermeable to at least liquid. 20. The method of claim 19, wherein the membrane is a hydrophobic membrane. 21. The method of claim 20, wherein the pressure control device includes a filter that prevents at least one contaminant from entering the organ cassette. 22. The method of claim 16, further comprising: placing the organ cassette containing the organ or tissue in the portable perfusion device, without removal of the organ or tissue from the organ cassette; andtransporting the organ or tissue in the organ cassette in the portable perfusion device. 23. The method of claim 16, further comprising: placing the organ or tissue on an organ supporting surface within the organ cassette that is configured to support the organ or tissue within the organ cassette while allowing effluent medical fluid to pass through the organ or tissue. 24. The method of claim 23, the method further comprising: maintaining the effluent medical fluid at a desired pressure. 25. The method of claim 24, wherein the desired pressure is atmospheric pressure. 26. The method of claim 24, wherein the desired pressure is maintained by a pressure sensor. 27. A method of at least two of perfusion, storage, and transport of an organ or tissue, comprising: placing the organ or tissue in an organ cassette that is configured to be received by at least one of a perfusion device, a portable perfusion device and a diagnostic device, the organ cassette including: a wall that at least partially delimits a volume for holding the organ, anda plurality of lids that form at least one airtight seal with the wall, wherein at least two of the plurality of lids are configured to each individually form an airtight seal with the wall by coming into sealing contact with the wall;separately opening or closing at least one of the plurality of lids without opening or closing at least one other of the plurality of lids; andcontrolling the pressure within the organ cassette by at least one pressure control device,wherein at least one of the lids includes the at least one pressure control device. 28. The method of claim 27, wherein the at least one pressure control device is at least one of a closable vent, a pressure control valve and a membrane that is substantially impermeable to at least liquid. 29. The method of claim 28, wherein at least two of the lids each includes two pressure control devices. 30. The method of claim 28, wherein at least two of the lids each includes a pressure control device. 31. The method of claim 28, wherein the membrane is a hydrophobic membrane. 32. The method of claim 27, wherein controlling the pressure includes maintaining pressure of the organ cassette at a desired pressure. 33. The method of claim 32, wherein the desired pressure is atmospheric pressure. 34. The method of claim 27, wherein the pressure control device includes a filter that prevents at least one contaminant from entering the organ cassette. 35. The method of claim 27, wherein the organ cassette includes an organ or tissue supporting surface configured to support the organ or tissue, the method further comprising: placing the organ or tissue supporting surface supporting the organ or tissue in an organ perfusion apparatus; andperfusing the organ or tissue in the organ cassette in the organ perfusion apparatus. 36. The method of claim 27, further comprising: placing the organ cassette containing the organ or tissue in at least one of the portable perfusion device and the perfusion device, without removal of the organ or tissue from the organ cassette. 37. The method of claim 36, further comprising: placing the organ cassette containing the organ or tissue in the portable perfusion device; andtransporting the organ or tissue in the organ cassette in the portable perfusion device, without removal of the organ or tissue from the organ cassette. 38. The method of claim 27, further comprising controlling a pressure inside the organ cassette so that the pressure inside the organ cassette is substantially equal to a pressure outside the organ cassette.
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Klatz Ronald M. (1510 Montana St. Chicago IL 60614) Goldman Robert M. (2434 N. Greenview Chicago IL 60614), Brain resuscitation device and method for performing the same.
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Bradley Laurie (55 Alpine Avenue Surbiton ; Surrey GB2) Lilleystone Richard J. (32 High Pine Close Weybridge ; Surrey GB2) Cumner Clive S. (Surrey GB2), Container for the preservation and transportation of severed limbs or other body parts.
Guilhem Jacques R. J. (28 rue du Commandant Henry Vesco 78 310 Sainte-Adresse FRX) Wengler Roger L. L. (37 rue Mac Orlan 76 600 Le Havre FRX), Container for transporting grafts.
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Beisang ; III Arthur A. (Little Canada MN) Ersek Robert A. (Austin TX) Beisang Arthur A. (Roseville MN), Moldable cooling/heating device with directional cooling/heating.
Sites Jeffrey P. ; Glassel Philip R. ; Miller Michael D. ; Norgaard Clark B. ; Roman Thomas A. ; Ziebarth Dale J., Perfusion hyperthermia treatment system and method.
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Osterholm Jewell L. (Radnor Township ; Delaware County PA), Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ische.
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