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[미국특허] Fixed dosing of HER antibodies 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-039/395
출원번호 US-0248223 (2008-10-09)
등록번호 US-8404234 (2013-03-26)
발명자 / 주소
  • Allison, David E.
  • Bruno, Rene
  • Lu, Jian-Feng
  • Ng, Chee M.
출원인 / 주소
  • Genentech, Inc.
대리인 / 주소
    Lee, Wendy M.
인용정보 피인용 횟수 : 6  인용 특허 : 98

초록

The present invention concerns fixed dosing of HER antibodies, such as Pertuzumab.

대표청구항 ▼

1. An article of manufacture comprising a single dose vial containing a single fixed dose of pertuzumab, wherein the fixed dose is selected from the group consisting of 420 mg and 840 mg of pertuzumab. 2. The article of manufacture of claim 1 further comprising a package insert instructing the user

이 특허에 인용된 특허 (98) 인용/피인용 타임라인 분석

  1. Fendly,Brian M., Anti-ErbB2 antibodies.
    상세보기
  2. King C. Richter (Washington DC) Kasprzyk Philip G. (Washington DC) Bird Robert E. (Rockville MD), Anti-erbB-2 antibodies, combinations thereof, and therapeutic and diagnostic uses thereof.
    상세보기
  3. Shawver Laura K. ; Brandis John W. ; Mann Elaina ; Hancock Miriam E. C. ; Mischak Ronald P. ; Monahan John J., Anti-neoplastic drugs in cancer therapy.
    상세보기
  4. Ebens, Jr., Allen J.; Jacobson, Frederic S.; Polakis, Paul; Schwall, Ralph H.; Sliwkowski, Mark X.; Spencer, Susan D., Antibody-drug conjugates and methods.
    상세보기
  5. Arakawa Tsutomu ; Kita Yoshiko, Antibody-induced apoptosis.
    상세보기
  6. Tsutomu Arakawa ; Yoshiko Kita, Antibody-induced apoptosis.
    상세보기
  7. Plowman Gregory D., Assay for agents active in proliferative disorders.
    상세보기
  8. Ross Jeffrey S. ; Muraca Patrick J., Assessment of prostate cancer.
    상세보기
  9. Sliwkowski, Mark X.; Kelsey, Stephen M., Combination therapy of her expressing tumors.
    상세보기
  10. Huston James S. ; Houston L. L. ; Ring David B. ; Oppermann Hermann, DNA encoding biosynthetic binding protein for cancer marker.
    상세보기
  11. Kraus Matthias H. (Bethesda MD) Aaronson Stuart A. (Vienna VA), DNA segment encoding a gene for a receptor related to the epidermal growth factor receptor.
    상세보기
  12. Carney Walter P. (North Andover MA) McKenzie Sara J. (Lynn MA), Detection and quantification of neu related proteins in the biological fluids of humans.
    상세보기
  13. Mass, Robert D., Detection of ErbB2 gene amplification to increase the likelihood of the effectiveness of ErbB2 antibody breast cancer therapy.
    상세보기
  14. Carney, Walter P.; McKenzie, Sara J.; Weinberg, Robert A., Detection of neu p185 in cell lysates.
    상세보기
  15. Bargmann Cornelia I. (Arlington MA) Weinberg Robert A. (Brookline MA), Detection of point mutations in neu genes.
    상세보기
  16. Slamon Dennis J. (Woodland Hills CA) McGuire William L. (San Antonio TX), Determination of status in neoplastic disease.
    상세보기
  17. Baughman, Sharon A.; Shak, Steven, Dosages for treatment with anti-ErbB2 antibodies.
    상세보기
  18. Baughman,Sharon A.; Shak,Steven, Dosages for treatment with anti-ErbB2 antibodies.
    상세보기
  19. Carter Paul J. (San Francisco CA), Expression of functional antibody fragments.
    상세보기
  20. Allison,David E.; Bruno,Rene; Lu,Jian Feng; Ng,Chee M., Fixed dosing of HER antibodies.
    상세보기
  21. Mass, Robert D., Gene detection assay for improving the likelihood of an effective response to a HER2 antibody cancer therapy.
    상세보기
  22. Jensen Ronald H. ; Cher Michael L., Genetic alterations associated with prostate cancer.
    상세보기
  23. Slamon, Dennis J.; Wilson, Cindy A.; Calzone, Frank J., HER-2/neu overexpression abrogates growth inhibitory pathways.
    상세보기
  24. Kao, Yung Hsiang; Vanderlaan, Martin, HER2 antibody composition.
    상세보기
  25. Kao, Yung-Hsiang; Vanderlaan, Martin, HER2 antibody composition.
    상세보기
  26. Hudziak Robert Michael ; Shepard H. Michael ; Ullrich Axel, HER2 extracellular domain.
    상세보기
  27. Hudziak Robert Michael ; Shepard H. Michael ; Ullrich Axel,DEX, HER2 extracellular domain.
    상세보기
  28. Marks James D. ; Schier Robert, High affinity human antibodies to tumor antigens.
    상세보기
  29. Marks, James D.; Schier, Robert, High affinity human antibodies to tumor antigens.
    상세보기
  30. Adams, Camellia W.; Presta, Leonard G.; Sliwkowski, Mark, Humanized anti-ERBB2 antibodies and treatment with anti-ERBB2 antibodies.
    상세보기
  31. Adams, Camellia W.; Presta, Leonard G.; Sliwkowski, Mark, Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies.
    상세보기
  32. Sliwkowski, Mark, Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies.
    상세보기
  33. Carter Paul J. ; Presta Leonard G., Humanized antibodies and methods for making them.
    상세보기
  34. Carter Paul J. ; Presta Leonard G., Immunoglobulin variants.
    상세보기
  35. Benz Christopher C. ; Papahadjopoulos Demetrios P. ; Park John W. ; Hong Keelung ; Kirpotin Dmitri, Immunoliposomes that optimize internalization into target cells.
    상세보기
  36. Hudziak Robert M. ; Ullrich Axel ; Fendly Brian M., In vivo tumor detection assay.
    상세보기
  37. Kraus Matthias H. (Bethesda MD) Aaronson Stuart A. (Vienna VA), Isolated polypeptide erbB-3, related to the epidermal growth factor receptor and antibody thereto.
    상세보기
  38. Deborah R. Jaffee ; Kerry J. Flom, Method and kit for the prognostication of breast cancer.
    상세보기
  39. Carter, Paul J.; Presta, Leonard G., Method for making humanized antibodies.
    상세보기
  40. Carter, Paul J.; Presta, Leonard G., Method for making humanized antibodies.
    상세보기
  41. Carter, Paul J.; Presta, Leonard G., Method for making humanized antibodies.
    상세보기
  42. Carter, Paul J.; Presta, Leonard G., Method for making humanized antibodies.
    상세보기
  43. Paul J. Carter ; Leonard G. Presta, Method for making humanized antibodies.
    상세보기
  44. Moecks, Joachim; Strauss, Andreas; Zugmaier, Gerhard, Method for predicting the response to a treatment.
    상세보기
  45. Bacus Sarah S. (Hinsdale IL), Method for prognosticating response to cancer therapy.
    상세보기
  46. Vandlen Richard L. (Hillsborough CA) Holmes William E. (Pacifica CA), Method for purifying heregulin.
    상세보기
  47. Wang Mary Ge ; George ; Jr. Albert Louis ; Light Elizabeth Sophia, Method for the detection of chromosome structural abnormalities by in situ hybridization to fixed tissue.
    상세보기
  48. Danenberg, Kathleen D., Method of determining a chemotherapeutic regimen based on ERCC1 expression.
    상세보기
  49. Danenberg, Kathleen D., Method of determining epidermal growth factor receptor and HER2-neu gene expression and correlation of levels thereof with survival rates.
    상세보기
  50. Bacus Sarah S. (Hinsdale IL), Methods and compositions for cancer therapy and for prognosticating responses to cancer therapy.
    상세보기
  51. Koski Raymond A., Methods and compositions for determining HER-2/neu expression using monoclonal antibodies.
    상세보기
  52. Curiel David T. ; Deshane Jessy, Methods for modulating protein function in cells using intracellular antibody homologues.
    상세보기
  53. Curiel David T. ; Deshane Jessy, Methods for modulating protein function in cells using, intracellular antibody homologues.
    상세보기
  54. Greene Mark I., Methods of treating cancerous cells with anti-receptor antibodies.
    상세보기
  55. Erickson, Sharon; Schwall, Ralph; Sliwkowski, Mark; Blattler, Walter, Methods of treatment using anti-ErbB antibody-maytansinoid conjugates.
    상세보기
  56. Erickson,Sharon; Schwall,Ralph; Sliwkowski,Mark; Blattler,Walter, Methods of treatment using anti-ErbB antibody-maytansinoid conjugates.
    상세보기
  57. Hudziak Robert M. (Corvallis OR) Shepard H. Michael (Rancho Santa Fe CA) Ullrich Axel (Portola Valley CA) Fendly Brian M. (Half Moon Bay CA), Monoclonal antibodies directed to the HER2 receptor.
    상세보기
  58. Hudziak Robert M. ; Shepard H. Michael ; Ullrich Axel ; Fendly Brian M., Monoclonal antibodies directed to the HER2 receptor.
    상세보기
  59. Hudziak Robert M. ; Shepard H. Michael ; Ullrich Axel ; Fendly Brian M., Monoclonal antibodies directed to the HER2 receptor.
    상세보기
  60. Hudziak Robert M. ; Shepard H. Michael ; Ullrich Axel ; Fendly Brian M., Monoclonal antibodies directed to the HER2 receptor.
    상세보기
  61. Hudziak Robert M. ; Ullrich Axel ; Fendly Brian M., Monoclonal antibodies directed to the HER2 receptor.
    상세보기
  62. Robert M. Hudziak ; H. Michael Shepard ; Axel Ullrich ; Brian M. Fendly, Monoclonal antibodies directed to the HER2 receptor.
    상세보기
  63. Robert M. Hudziak ; H. Michael Shepard ; Axel Ullrich ; Brian M. Fendly, Monoclonal antibodies directed to the HER2 receptor.
    상세보기
  64. Hudziak Robert M. ; Shepard H. Michael ; Ullrich Axel ; Fendly Brian M., Monoclonal antibodies directed to the her2 receptor.
    상세보기
  65. Amler, Lukas C.; Birkner, Merrill; Lin, Chin-Yu; Moecks, Joachim; Strauss, Andreas, Predicting response to a HER inhibitor.
    상세보기
  66. Andya James ; Cleland Jeffrey L. ; Hsu Chung C. ; Lam Xanthe M. ; Overcashier David E. ; Shire Steven J. ; Yang Janet Yu-Feng ; Wu Sylvia Sau-Yan, Protein formulation.
    상세보기
  67. Andya, James; Cleland, Jeffrey L.; Hsu, Chung C.; Lam, Xanthe M.; Overcashier, David E.; Shire, Steven J.; Yang, Janet Yu-Feng; Wu, Sylvia Sau-Yan, Protein formulation.
    상세보기
  68. Andya, James; Cleland, Jeffrey L.; Hsu, Chung C.; Lam, Xanthe M.; Overcashier, David E.; Shire, Steven J.; Yang, Janet Yu-Feng; Wu, Sylvia Sau-Yan, Protein formulation.
    상세보기
  69. Cleland, Jeffrey L.; Hsu, Chung C.; Lam, Xanthe M.; Overcashier, David E.; Yang, Janet Yu-Feng, Protein formulation.
    상세보기
  70. Basey,Carol D.; Blank,Greg S., Protein purification.
    상세보기
  71. Blank Gregory S., Protein purification.
    상세보기
  72. Blank, Gregory S., Protein purification.
    상세보기
  73. Carol D. Basey ; Greg S. Blank, Protein purification.
    상세보기
  74. Carol D. Basey ; Greg S. Blank, Protein purification.
    상세보기
  75. Carol D. Basey ; Greg S. Blank, Protein purification.
    상세보기
  76. Blank Gregory S., Protein purification by Protein A chromatography.
    상세보기
  77. King C. Richter ; Kraus Matthias H. ; Aaronson Stuart A., Protein related to but distinct from EGF receptor and antibodies reactive therewith.
    상세보기
  78. Slamon Dennis J. ; Press Michael F., Quantitative measurement of tissue protein identified by immunohistochemistry and standardized protein determination.
    상세보기
  79. Wels Winfried S. (Basel CHX) Hynes Nancy E. (Basel CHX) Harweth Ina-Maria (Grenzach-Wyhlen DEX) Groner Bernd (Basel CHX) Hardman Norman (Riehen CHX) Zwickl Markus (Basel CHX), Recombinant antibodies specific for a growth factor receptor.
    상세보기
  80. Wels Winfried Stephan,CHX ; Hynes Nancy E.,CHX ; Harwerth Ina-Maria,DEX ; Groner Bernd,CHX ; Hardman Norman,CHX ; Zwickl Markus,CHX, Recombinant antibodies specific for a growth factor receptor.
    상세보기
  81. Erickson, Sharon; King, Kathleen; Schwall, Ralph, Rodent HER2 tumor model.
    상세보기
  82. Deo Yashwant M. ; Goldstein Joel ; Graziano Robert ; Somasundaram Chezian, Therapeutic compounds comprised of anti-Fc receptor antibodies.
    상세보기
  83. Deo Yashwant M. ; Goldstein Joel ; Graziano Robert ; Somasundaram Chezian, Therapeutic compounds comprised of anti-Fc receptor antibodies.
    상세보기
  84. Yashwant M. Deo ; Joel Goldstein ; Robert Graziano ; Chezian Somasundaram, Therapeutic compounds comprised of anti-Fc receptor antibodies.
    상세보기
  85. Deo Yashwant M. ; Graziano Robert ; Keler Tibor, Therapeutic multispecific compounds comprised of anti-Fc.alpha. receptor antibodies.
    상세보기
  86. Cohen, Robert L.; Gardiner, Mary Beth; Sliwkowski, Mark X.; Stelzer, Gregory T., Tissue analysis and kits therefor.
    상세보기
  87. Andrew J. Dannenberg ; Kotha Subbaramaiah, Treating cancers associated with overexpression of HER-2/neu.
    상세보기
  88. Sliwkowski,Mark X., Treating prostate cancer with anti-ErbB2 antibodies.
    상세보기
  89. Greene Mark I. ; Drebin Jeffrey A., Treatment of tumors with monoclonal antibodies against oncogene antigens.
    상세보기
  90. Hellmann, Susan D., Treatment with anti-ErbB2 antibodies.
    상세보기
  91. Hellmann, Susan D., Treatment with anti-ErbB2 antibodies.
    상세보기
  92. Paton, Virginia E.; Shak, Steven; Hellmann, Susan D., Treatment with anti-ErbB2 antibodies.
    상세보기
  93. Sliwkowski, Mark, Treatment with anti-ErbB2 antibodies and EGFR-targeted drugs.
    상세보기
  94. Adams,Camellia W.; Presta,Leonard G.; Sliwkowski,Mark, Treatment with anti-ErbB2 antibodies and anti-hormonal compounds.
    상세보기
  95. Adams,Camellia W.; Presta,Leonard G.; Sliwkowski,Mark, Treatment with anti-ErbB2 antibodies and chemotherapeutic agents.
    상세보기
  96. Adams,Camellia W.; Presta,Leonard G.; Sliwkowski,Mark, Treatment with anti-ErbB2 antibody combinations.
    상세보기
  97. Vogel Charles L. ; Bellet Robert E., Use of docetaxel for treating cancers.
    상세보기
  98. King C. Richter ; Kraus Matthias H. ; Aaronson Stuart A., erbB-2 gene segments, probes, recombinant DNA and kits for detection.
    상세보기

이 특허를 인용한 특허 (6) 인용/피인용 타임라인 분석

  1. Harris, Reed J.; Motchnik, Paul A., Composition comprising antibody that binds to domain II of HER2 and acidic variants thereof.
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  2. Derynck, Mika K.; Kelsey, Stephen M., Extending time to disease progression or survival in cancer patients.
    상세보기
  3. Andya, James; Gwee, Shiang C.; Liu, Jun; Shen, Ye, Method of treating cancer with a pharmaceutical formulation comprising a HER2 antibody.
    상세보기
  4. Gennaro, Lynn A.; Kao, Yung-Hsiang; Zhang, Yonghua, Pertuzumab variants and evaluation thereof.
    상세보기
  5. Gennaro, Lynn A.; Kao, Yung-Hsiang; Zhang, Yonghua, Pertuzumab variants and evaluation thereof.
    상세보기
  6. Amler, Lukas C.; Birkner, Merrill; Lin, Chin-Yu; Moecks, Joachim; Strauss, Andreas, Predicting response to a HER inhibitor.
    상세보기

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