Removal of acids from tertiary amide solvents
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
C07H-001/06
C07H-005/02
출원번호
US-0403762
(2009-03-13)
등록번호
US-8476424
(2013-07-02)
발명자
/ 주소
Kerr, John
Jansen, Robert
Isaac, Christian J.
Wiley, Jr., James Edwin
Leinhos, Duane A.
출원인 / 주소
Tate & Lyle Technology Limited
대리인 / 주소
RatnerPrestia
인용정보
피인용 횟수 :
0인용 특허 :
49
초록▼
A method of removing a carboxylic acid from a liquid that contains a tertiary amide solvent includes a step of contacting the liquid with an extraction medium comprising an amine. The amine is immiscible with both water and the tertiary amide solvent, and the contacting step forms a de-acidified pha
A method of removing a carboxylic acid from a liquid that contains a tertiary amide solvent includes a step of contacting the liquid with an extraction medium comprising an amine. The amine is immiscible with both water and the tertiary amide solvent, and the contacting step forms a de-acidified phase containing the tertiary amide solvent and a phase containing the extraction medium and the carboxylic acid. Both the liquid that contains the tertiary amide solvent and the de-acidified phase may also contain a sucrose-6-acylate.
대표청구항▼
1. A method of removing a carboxylic acid from a liquid comprising a tertiary amide solvent, the method comprising a step of contacting the liquid comprising the tertiary amide solvent and the carboxylic acid with an extraction medium comprising an amine that is immiscible with both water and the te
1. A method of removing a carboxylic acid from a liquid comprising a tertiary amide solvent, the method comprising a step of contacting the liquid comprising the tertiary amide solvent and the carboxylic acid with an extraction medium comprising an amine that is immiscible with both water and the tertiary amide solvent, thereby forming a phase comprising de-acidified tertiary amide solvent and a phase comprising the extraction medium and the carboxylic acid. 2. The method of claim 1, wherein the tertiary amide solvent is dimethyl formamide. 3. The method of claim 1, additionally comprising a step of treating the de-acidified tertiary amide solvent to further purify it. 4. The method of claim 3, wherein the step of treating comprises distilling or evaporating and condensing the tertiary amide solvent. 5. The method of claim 1, wherein the amine is a monoamine not comprising any heteroatoms other than the nitrogen atom of the amine. 6. The method of claim 1, wherein the amine is a tertiary amine. 7. The method of claim 1, wherein the amine is according to the formula NR1R2R3 where each of R1, R2 and R3 is independently selected from the group consisting of H and C1-C20 linear or branched alkyl, cyclic, alicyclic, alkenyl, aryl, aralkyl, and alkaryl groups, provided that at least one of R1, R2 and R3 is not H. 8. The method of claim 7, wherein the total number of carbon atoms in R1, R2 and R3 combined is at least 24. 9. The method of claim 1, wherein the amine comprises trilaurylamine. 10. The method of claim 1, wherein the amine does not have a boiling point lower than that of the tertiary amide solvent. 11. The method of claim 1, wherein the amine has a melting point of at most 20° C. 12. The method of claim 1, wherein the extraction medium comprises a mixture of the amine with a water-immiscible alcohol R1OH, wherein R1 is a C7-C20 hydrocarbyl group. 13. The method of claim 12, wherein the water-immiscible alcohol comprises dodecanol. 14. The method of claim 1, wherein the carboxylic acid comprises acetic acid, formic acid, or a mixture of these. 15. The method of claim 1, further comprising the steps of washing the phase comprising the extraction medium and the carboxylic acid with water at a temperature in a range from 10° C. to 40° C. to form a purified extraction medium;washing the purified extraction medium with water at a temperature in a range from 50° C. to 90° C. to give a partially de-acidified extraction medium; andwashing the partially de-acidified extraction medium with an aqueous base to give a substantially de-acidified extraction medium. 16. The method of claim 1, wherein the tertiary amide solvent constitutes at least 60 wt % of the liquid. 17. The method of claim 1, further comprising forming a solution of sucrose in the resulting tertiary amide solvent and subsequently converting the sucrose to sucralose. 18. The method of claim 17, wherein said converting comprises converting the sucrose to a sucrose-6-acylate and subsequently converting the sucrose-6-acylate to sucralose. 19. The method of claim 18, wherein the sucrose-6-acylate is sucrose-6-acetate. 20. The method of claim 1, wherein both the liquid comprising the tertiary amide solvent and the phase comprising de-acidified tertiary amide solvent further comprise a sucrose-6-acylate. 21. The method of claim 20, further comprising converting the sucrose-6-acylate to sucralose. 22. The method of claim 20, wherein the sucrose-6-acylate is sucrose-6-acetate.
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이 특허에 인용된 특허 (49)
Lee Cheang K. (Singapore SGX), 4′-Halo-substituted sucrose derivatives.
O\Brien Eleanor A. (Dublin IEX) O\Connor Thomas (Dublin IEX) Tuite Mathew R. J. (Dublin NJ IEX) High Leroy B. (Cranbury NJ), Chlorination of carbohydrates and other alcohols.
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Bornemann Stephen (Leamington Spa GB3) Cassells John M. (St. Ives GB3) Combes Clive L. (Reading IA GB3) Dordik Jonathan S. (Iowa City IA) Hacking Andrew J. (Mortimer GB3), Preparation of acylated sucrose derivatives.
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Jenner Michael R. (Pangbourne GB2) Waite David (Reading GB2) Jackson Graham (Reading GB2) Williams John C. (Wokingham GB2), Process for the preparation of 4,1′,6′-trichloro-4,1′,6′-trideoxygalactosucrose.
Khan Riaz A. (Sonning GB2) Smith Keith (Mayals GB2) Pelter Andrew (Uplands GB2) Zhao Jin (Uplands GB2), Process for the preparation of sucrose 6-esters.
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McNally Gerard P. (Strafford PA) Roche Edward J. (Paoli PA), Stabilized composition of famotidine and sucralfate for treatment of gastrointestinal disorders.
Navia Juan L. (Athens GA) Walkup Robert E. (Watkinsville GA) Vernon Nicholas M. (Durham GA GB2) Wingard ; Jr. Robert E. (Athens GA), Sucralose pentaester production.
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