IPC분류정보
| 국가/구분 |
United States(US) Patent
등록
|
| 국제특허분류(IPC7판) |
|
| 출원번호 |
US-0941060
(2007-11-15)
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| 등록번호 |
US-8556989
(2013-10-15)
|
|
발명자
/ 주소 |
- Bartee, Chad M.
- Bartee, Barry K.
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| 출원인 / 주소 |
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| 대리인 / 주소 |
Pillsbury Winthrop Shaw Pittman LLP
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| 인용정보 |
피인용 횟수 :
0 인용 특허 :
44 |
초록
▼
A medical barrier includes a sheet of unsintered substantially unexpanded hydrophilic polytetraflouroethylene (PTFE) polymer material. A PTFE polymer material is described that has a density in a range of about 1.2 gm/cc to about 2.3 gm/cc, and preferably in the range of about 1.45 gm/cc to about 1.
A medical barrier includes a sheet of unsintered substantially unexpanded hydrophilic polytetraflouroethylene (PTFE) polymer material. A PTFE polymer material is described that has a density in a range of about 1.2 gm/cc to about 2.3 gm/cc, and preferably in the range of about 1.45 gm/cc to about 1.55 gm/cc, and having at least one textured surface. In accordance with one embodiment, the sheet has one textured surface and one substantially smooth surface, and has substantially uniform strength in all directions.
대표청구항
▼
1. A guided tissue regeneration membrane comprising a multi-surfaced polytetrafluoroethylene sheet having a portion of one surface of the polytetrafluoroethylene sheet that is hydrophilic, which renders the membrane surface substantially compatible with water, body fluids, blood and aqueous solution
1. A guided tissue regeneration membrane comprising a multi-surfaced polytetrafluoroethylene sheet having a portion of one surface of the polytetrafluoroethylene sheet that is hydrophilic, which renders the membrane surface substantially compatible with water, body fluids, blood and aqueous solutions, wherein the hydrophilic portion is limited to a central portion of the membrane and comprises an embossed portion, wherein embossments of the hydrophilic portion are etched by one or more of glow discharge plasma and a laser. 2. A medical barrier comprising a multi-surfaced membrane,wherein the membrane comprises a sheet of high density, unexpanded, unsintered polytetrafluoroethylene,wherein one surface of the membrane is embossed and treated, after embossing, by addition of one or more of a polymer, a reactive chemical, and an etching of the surface, thereby providing a limited portion of the one surface that is compatible with one or more fluids, andwherein the medical barrier is adaptable for use in guided tissue regeneration in the repair of bone defects. 3. The medical barrier of claim 2, wherein the limited portion of the one surface is substantially compatible with water. 4. The medical barrier of claim 2, wherein the limited portion of the one surface is substantially compatible with body fluids. 5. The medical barrier of claim 2, wherein the limited portion of the one surface is substantially compatible with blood. 6. The medical barrier of claim 2, wherein the limited portion of the one surface is substantially compatible with water, body fluids, blood and aqueous solutions. 7. The medical barrier of claim 6, wherein the embossed portion is treated with at least one of a hydrophilic polymer and a reactive chemical. 8. The medical barrier of claim 7, wherein the embossed portion is linked via covalent bonds to bioactive molecules. 9. The medical barrier of claim 8, wherein the bioactive molecules include one or more of a growth factor, a cytokine, morphogenetic protein, a cell attractant, and an adhesion molecule. 10. The medical barrier of claim 9, wherein the source of the bioactive molecules is selected from the group consisting of autologous, allogenic, xenogenic and synthetic. 11. A tissue regeneration membrane usable as a medical barrier and comprising a high density polytetrafluoroethylene sheet having a plurality of surfaces, wherein the membrane comprises high density, unexpanded, unsintered PTFE, wherein an embossment of a selected portion of one of the plurality of surfaces is treated by one or more of polymer coating, a chemical reaction, and an etching, thereby making the selected portion of the one surface hydrophilic and substantially compatible with water, body fluids, blood and aqueous solutions, and wherein the medical barrier provides for guided tissue regeneration. 12. The tissue regeneration membrane of claim 11, wherein medical barrier is adapted for use in the repair of bone defects. 13. The tissue regeneration membrane of claim 11, wherein the selected portion of the one surface includes an embossed portion treated with a hydrophilic polymer. 14. The tissue regeneration membrane of claim 11, wherein the selected portion of the one surface is treated by chemical reaction. 15. The tissue regeneration membrane of claim 11, wherein the selected portion of the one surface is treated by etching. 16. The tissue regeneration membrane of claim 15, wherein one of the plurality of surfaces is textured and wherein another of the plurality of surfaces is substantially smooth. 17. The tissue regeneration membrane of claim 11, wherein the selected portion is provided at the periphery of the membrane and comprises a border of the membrane. 18. The tissue regeneration membrane of claim 11, wherein the selected portion is limited to a central portion of the membrane. 19. The medical barrier of claim 2, wherein the embossed portion is treated with a hydrophilic chemical. 20. The medical barrier of claim 2, wherein the embossed portion is laser etched. 21. The medical barrier of claim 2, wherein the embossed portion is etched by glow discharge plasma.
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