Use of silymarin and/or constituents thereof as skin or hair pigmentation promoters
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A01K-043/32
A61K-031/335
출원번호
US-0818943
(2006-02-13)
등록번호
US-8569358
(2013-10-29)
우선권정보
FR-05 01446 (2005-02-11)
발명자
/ 주소
Bernard, Philippe
Bernard, Francois-Xavier
출원인 / 주소
GreenPharma
대리인 / 주소
Oliff & Berridge, PLC
인용정보
피인용 횟수 :
1인용 특허 :
3
초록▼
Describe is a method of administering to a subject silymarin, or of the main constituents thereof alone or as a mixture, chosen from silybin (or 2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3, 5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxine), isosilybin, silydianin, silychristin,
Describe is a method of administering to a subject silymarin, or of the main constituents thereof alone or as a mixture, chosen from silybin (or 2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3, 5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxine), isosilybin, silydianin, silychristin, silandrin, silymonin and taxifolin, isolated enantiomers thereof and also salts thereof.
대표청구항▼
1. A method of inducing or stimulating pigmentation of skin in a subject in need of such inducing or stimulating, the method comprising administering to the subject silybin (or 2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxine), isolate
1. A method of inducing or stimulating pigmentation of skin in a subject in need of such inducing or stimulating, the method comprising administering to the subject silybin (or 2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxine), isolated enantiomers thereof and/or salts thereof to induce or stimulate the pigmentation of skin in the subject. 2. The method of claim 1, wherein the silybin is obtained by extraction of a plant of the genus Silybum. 3. The method of claim 1, wherein the silybin is obtained by semi-synthesis or synthesis. 4. The method of claim 1, wherein the silybin is enantiomerically pure. 5. The method of claim 1, wherein the administration is in a composition comprising from about 0.01% to 10% by weight of silybin. 6. The method of claim 5, wherein the composition comprises from about 0.1% to 2.5% by weight of silybin. 7. The method of claim 5, wherein the composition comprises from about 0.01% to 2.5% by weight of silybin. 8. A method of restoring pigmentation of skin in a subject suffering from hypopigmentation, the method comprising administering to the subject silybin (or 2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxine), isolated enantiomers thereof and/or salts thereof to restore the pigmentation of skin in the subject.
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이 특허에 인용된 특허 (3)
Kim Plaschke DK, Composition comprising one or more flavonoids, method of obtaining such composition and use thereof as UV-absorbing agent.
Dubief Claude,FRX ; Braida-Valerio Damarys,FRX, Use of flavonoids for preserving and/or enhancing the mechanical properties of the hair and process for protecting the.
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