최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0704896 (2007-02-09) |
등록번호 | US-8585377 (2013-11-19) |
발명자 / 주소 |
|
출원인 / 주소 |
|
대리인 / 주소 |
|
인용정보 | 피인용 횟수 : 4 인용 특허 : 425 |
A method of dispensing a therapeutic fluid from a line includes providing an inlet line connectable to an upstream fluid source. The inlet line is in downstream fluid communication with a pumping chamber. The pumping chamber has a pump outlet. The method also includes actuating a force application a
A method of dispensing a therapeutic fluid from a line includes providing an inlet line connectable to an upstream fluid source. The inlet line is in downstream fluid communication with a pumping chamber. The pumping chamber has a pump outlet. The method also includes actuating a force application assembly so as to restrict retrograde flow of fluid through the inlet while pressurizing the pumping chamber to urge flow through the pump outlet. A corresponding system employs the method.
1. A system for pumping a medical fluid through a line in an infusion pump, the system comprising: a pumping chamber in the infusion pump comprising: an inlet connectable to provide fluid communication with a fluid source; anda pump outlet;a force application assembly comprising an inlet sealing mem
1. A system for pumping a medical fluid through a line in an infusion pump, the system comprising: a pumping chamber in the infusion pump comprising: an inlet connectable to provide fluid communication with a fluid source; anda pump outlet;a force application assembly comprising an inlet sealing member and a pump compressing member, the force application assembly adapted to provide a compressive stroke to the pumping chamber, wherein the force application assembly effects sealing of the inlet prior to compression of the pumping chamber so as to urge flow through the outlet;an exit valve outside of the fluid line adapted to control fluid flow through the pump outlet; anda driving member that actuates both the inlet sealing member and the pump compressing member, the inlet sealing member comprising a sealing spring positioned between the driving member and an integral support of the sealing member, the inlet sealing member slidably seated in an opening of the driving member, and the pump compressing member comprising a return spring positioned between a distal compressing member support and the driving member;wherein during the compressive stroke, the driving member compresses the sealing spring to transmit a driving force to the sealing member via the integral support while the driving member slides along a shaft of the sealing member, even while driving the pump compressing member toward the pumping chamber;wherein the compressive stroke causes a restriction of retrograde flow of fluid from the pumping chamber through the inlet and causes an increase in pressure within the pumping chamber; andwherein the increase in pressure within the pumping chamber opens the exit valve and urges fluid from the pumping chamber to the pump outlet. 2. A system according to claim 1, wherein the force application assembly includes a pump plate coupled to the driving member for coordinated operation of the inlet sealing member and the pump compressing member. 3. A system according to claim 2, wherein the driving member includes a shape-memory actuator. 4. A system according to claim 3, wherein the driving member includes at least one pulley for folding the shape-memory actuator to fit within a reusable portion. 5. A system according to claim 1, wherein the driving member includes a motor. 6. A system according to claim 5, wherein the motor includes a shape-memory actuator. 7. A system according to claim 6, wherein the shape-memory actuator is electrically coupled so as to provide a plurality of electrical paths of different lengths through the shape-memory actuator. 8. A system according to claim 7, wherein the force application assembly has a normal mode for operating the pumping chamber under normal pumping conditions and a priming mode for priming the pumping chamber, and wherein a shorter electrical path of the shape-memory actuator is used during the normal mode of the force application assembly and a longer electrical path is used during the priming mode of the force application assembly. 9. A system according to claim 5, wherein the motor includes a plurality of shape-memory actuators. 10. A system according to claim 9, wherein the plurality of shape-memory actuators provide for redundant operation of the force application assembly. 11. A system according to claim 9, wherein different numbers of shape-memory actuators are used to provide different actuation forces or stroke lengths. 12. A system according to claim 9, wherein the plurality of shape-memory actuators includes shape-memory actuators of at least two different lengths. 13. A system according to claim 12, wherein the force application assembly has a normal mode for operating the pumping chamber under normal pumping conditions and a priming mode for priming the pumping chamber, and wherein a shorter shape-memory actuator is used during the normal mode of the force application assembly and a longer shape-memory actuator is used during the priming mode of the force application assembly. 14. A system according to claim 12, wherein the force application assembly operates in at least a basal mode and a bolus mode, the pumping chamber outputting fluid at a basal rate when in the basal mode, and the pumping chamber outputting fluid at a bolus rate when in the bolus mode, the bolus mode rate being greater than the basal mode rate, wherein a shorter shape-memory actuator is used during the basal mode of the force application assembly and a longer shape-memory actuator is used during the bolus mode of the force application assembly. 15. A system according to claim 9, wherein the plurality of shape-memory actuators includes shape-memory actuators of at least two different gauges. 16. A system according to claim 1 further comprising a downstream dispensing assembly in series with the pump outlet, the dispensing assembly comprising a resilient dispensing chamber. 17. A system according to claim 16, further comprising a sensor for measuring a parameter related to flow through the line. 18. A system according to claim 1, wherein the pumping chamber, the inlet, the outlet and the force actuation assembly are components of a fluid delivery device sized to be worn as a patch. 19. A system according to claim 16, further comprising a tortuous high-impedance conduit located downstream of the dispensing assembly. 20. A system according to claim 19, wherein the conduit has at least two turns. 21. A system according to claim 19, wherein the conduit is coiled. 22. A system according to claim 19, wherein the conduit has a serpentine shape. 23. A system according to claim 19, wherein the conduit has a length and an internal diameter selected to provide a predetermined impedance based on at least one of a viscosity and a density of the fluid. 24. A system according to claim 19, wherein an internal diameter of the conduit is sufficiently large so as to prevent occlusion due to flow of the medical fluid through the conduit. 25. A system according to claim 1 wherein at least a portion of the line is integral to a disposable component, the force application assembly is integral to a detachable reusable component, and the system further comprising a membrane material on the disposable component contiguous to the reusable component. 26. A system according to claim 25, wherein the membrane material overlies regions in the line that define the pumping chamber, an inlet valve, and the exit valve for enforcing unidirectional flow toward the pump outlet. 27. A system according to claim 26, wherein the force application assembly causes application of deforming forces to the membrane material overlying each of the regions defining the valves to effectuate closing of the valves. 28. A system according to claim 26, wherein the force application assembly causes application of a deforming force to the membrane material overlying the region defining the pumping chamber to effectuate urging of fluid from the pumping chamber. 29. A system according to claim 1 wherein the sealing spring is compressed while the pump compressing member exerts a pumping force upon the pumping chamber. 30. A system according to claim 29 wherein the pump compressing member further comprises a distal stop whereby the distal stop limits the return stroke via contact with the support. 31. A system according to claim 29 wherein the sealing member includes a proximal extension that extends beyond the opening of the driving member so that during the return stroke, the driving member engages and displaces the extension to allow flow through the inlet. 32. A system according to claim 1 wherein the driving member includes a shape memory actuator for actuating the force application assembly. 33. A system according to claim 1 wherein the exit valve comprises a poppet biased against a seated membrane by a poppet biasing spring. 34. A system according to claim 33 wherein a mechanical advantage favors lifting of the poppet.
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