초록 ▼

A microtitration plate has a frame (2) made of a first stiff plastic and having a plate (4) with multiplicity of holes (2′), and a multiplicity of vessels (3) made of a second plastic suited for the PCR and/or exhibiting permeability to oxygen, which are fixedly connected to the plate (4) by directl

A microtitration plate has a frame (2) made of a first stiff plastic and having a plate (4) with multiplicity of holes (2′), and a multiplicity of vessels (3) made of a second plastic suited for the PCR and/or exhibiting permeability to oxygen, which are fixedly connected to the plate (4) by directly molding them to the holes (6), which have a receiving portion (9, 10, 11) protruding from an underside (8) of the plate (4), and which are accessible from an upper surface (7) of the plate through apertures (15).

대표청구항 ▼

1. A method for manufacturing a microtitration plate, comprising: a frame (2) made of a first stiff plastic which has a plate (4) with a multiplicity of holes (2′) and a multiplicity of conical vessels (3) made of a second plastic which is suited for the PCR with regard to its softening temperature

1. A method for manufacturing a microtitration plate, comprising: a frame (2) made of a first stiff plastic which has a plate (4) with a multiplicity of holes (2′) and a multiplicity of conical vessels (3) made of a second plastic which is suited for the PCR with regard to its softening temperature and/or is a silicone, which are fixedly connected to the plate (4) by being directly molded to the holes (2′), have a receiving portion (9, 10, 11) protruding from the lower side (8) of the plate (4), and are accessible from the upper surface (7) of the plate through apertures (15),wherein the frame (2) and the vessels (3) are manufactured by a multi-component molding technique in which the frame (2) is molded first and the vessels (3) are molded subsequently, and in which the vessels (3) are molded each from a central molding point of their own, starting from their bottom (9). 2. The method according to claim 1, wherein the vessels (3) are molded at an interval from the molding of the frame (2) as substantially ensures the shrinking of the frame (2) completely before the vessels (3) are molded thereto. 3. A method for manufacturing a microtitration plate, comprising: a frame (2) made of a first stiff plastic which has a plate (4) with a multiplicity of holes (2′), a multiplicity of conical vessels (3) made of a second plastic which is suited for the PCR with regard to its softening temperature and/or is a silicone, which are fixedly connected to the plate (4) by being directly molded to the holes (2′), have a receiving portion (9, 10, 11) protruding from the lower side (8) of the plate (4), and are accessible from the upper surface (7) of the plate through apertures (15),wherein the frame (2) and the vessels (3) are manufactured in a multi-component molding technique in which the frame (2) is molded first and the vessels (3) are molded subsequently, and in which the vessels (3) are molded at an interval from the molding of the frame (2) as substantially ensures the shrinking of the frame (2) completely before the vessels (3) are molded thereto. 4. A method according to claim 3 wherein the vessels (3) are molded each from a central molding point of their own, starting from their bottom (9). 5. A method according to any one of claims 1-4 wherein the frame (2) is molded from several molding points in the marginal area. 6. A process for the manufacture of a microtitration plate comprising: a frame (2) made of a stiff first plastic which has a plate (4) with a multiplicity of holes (2′), and a multiplicity of conical vessels (3) made of a second plastic suited for the PCR and/or exhibiting permeability to oxygen, which are fixedly connected to the plate (4) by directly molding them to the holes (2′), have a receiving portion (9, 10, 11) protruding from the underside (8) of the plate (4), and are accessible from the upper surface (7) of the plate through apertures (15);wherein the frame (2) and the vessels (3) are manufactured in a multi-component molding technique; andwherein the vessels (3) are molded from their own central molding point each, starting from their bottom (9). 7. The process according to claim 6 wherein the frame (2) is molded initially and the vessels (3) are molded subsequently. 8. The process according to claim 6 or 7 wherein the vessels (3) are molded at such interval from the molding of the frame (2) as substantially ensures the shrinking of the frame (2) completely before the vessels (3) are molded thereto. 9. The process according to claim 7 wherein the frame (2) is molded from several molding points in the marginal area. 10. A process for the manufacture of a microtitration plate, said plate comprising a frame (2) made of a stiff first plastic which has a plate (4) with a multiplicity of holes (2′), and a multiplicity of conical vessels (3) made of a second plastic suited for the PCR and/or exhibiting permeability to oxygen, which are fixedly connected to the plate (4) by directly molding them to the holes (2′), have a receiving portion (9, 10, 11) protruding from the underside (8) of the plate (4), and are accessible from the upper surface (7) of the plate through apertures (15); wherein the frame (2) and the vessels (3) are manufactured in a multi-component molding technique;wherein the vessels (3) are molded at such interval from the molding of the frame (2) as substantially ensures the shrinking of the frame (2) completely before the vessels (3) are molded thereto. 11. The process according to claim 10 wherein the vessels (3) are molded each from a central molding point of their own, starting from their bottom (9). 12. The method of claim 1, wherein the vessels have wall thicknesses of about 0.05 to about 0.25 mm. 13. The method of claim 12, wherein the vessels have wall thicknesses of about 0.1 mm. 14. The method of claim 3, wherein the vessels have wall thicknesses of about 0.05 mm to about 0.25 mm. 15. The method of claim 14, wherein the vessels have wall thicknesses of about 0.1 mm. 16. The process of claim 6, wherein the vessels have wall thicknesses of about 0.05 mm to about 0.25 mm. 17. The process of claim 16, wherein the vessels have wall thicknesses of about 0.1 mm. 18. The process of claim 10, wherein the vessels have wall thicknesses of about 0.05 mm to about 0.25 mm. 19. The process of claim 18, wherein the vessels have wall thicknesses of about 0.1 mm.