$\require{mediawiki-texvc}$
  • 검색어에 아래의 연산자를 사용하시면 더 정확한 검색결과를 얻을 수 있습니다.
  • 검색연산자
검색도움말
검색연산자 기능 검색시 예
() 우선순위가 가장 높은 연산자 예1) (나노 (기계 | machine))
공백 두 개의 검색어(식)을 모두 포함하고 있는 문서 검색 예1) (나노 기계)
예2) 나노 장영실
| 두 개의 검색어(식) 중 하나 이상 포함하고 있는 문서 검색 예1) (줄기세포 | 면역)
예2) 줄기세포 | 장영실
! NOT 이후에 있는 검색어가 포함된 문서는 제외 예1) (황금 !백금)
예2) !image
* 검색어의 *란에 0개 이상의 임의의 문자가 포함된 문서 검색 예) semi*
"" 따옴표 내의 구문과 완전히 일치하는 문서만 검색 예) "Transform and Quantization"

통합검색

도움말도움말
상세검색 다국어 입력

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

특허 상세정보

MyON담기
내보내기 페이스북 공유 카카오톡 공유

Water-swellable polymers

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A61K-009/22    A61K-031/215   
미국특허분류(USC) 424/468; 514/530
출원번호 US-0571596 (2012-08-10)
등록번호 US-8628798 (2014-01-14)
우선권정보 GB-0222522.5 (2002-09-27)
발명자 / 주소
출원인 / 주소
대리인 / 주소
    Fish & Richardson P.C.
인용정보 피인용 횟수 : 2  인용 특허 : 263
초록
▼

A water-swellable linear polyurethane polymer is formed by reacting a polyethylene oxide (e.g. PEG 4000 to 35,000), a difunctional compound (e.g. a diamine or diol such as 1,10-decanediol) with a diisocyanate. The ratio of the three components is generally in the range 0.1-1.5 to 1 to 1.1-2.5. The polyurethane is water-swellable in the range 300 to 1700% and soluble in certain organic solvents such as dichloromethane. It can be loaded with pharmaceutically active agents, particularly of high molecular weight, to produce controlled release compositions, s...

대표
청구항
▼

1. A controlled release composition, comprising a cross-linked polyurethane polymer loaded with misoprostol; wherein the cross-linked polyurethane polymer is formed from a polyethylene glycol, a triol and a diisocyanate and the composition comprises 200 μg of misoprostol. 2. The composition of claim 1, wherein the cross-linked polyurethane polymer is formed from PEG8000, hexanetriol and dicyclohexylmethane-4.4-diisocyanate. 3. The composition of claim 2, wherein the ratio of PEG8000: hexanetriol:dicyclohexylmethane-4.4-diisocyanate is 1.0:1.2:2.8. 4. The...

이 특허에 인용된 특허 (263)

  1. Bartrol Javier (Barcelona ESX) Anguita Manuel (Barcelona ESX) Carceller Elena (Barcelona ESX). 2-picolylamine derivatives. USP1992075134151.
  2. Coleman Charles R. (Pittsburgh PA). Abrasion resistant polyurethane coatings for rigid plastics. USP1988034731289.
  3. Wolfgang Kaufhold DE; Hans-Georg Hoppe DE; Herbert Heidingsfeld DE; Rainer Ohlinger DE; Michael Kalbe DE. Aliphatic, low-emission thermoplastic polyurethane molding materials suitable for sintering. USP2002076420510.
  4. Klein Robert W. ; Packman Albert M.. Anti-acne method and composition. USP2000016013637.
  5. Ahmad Nawaz (Monmouth Jct. NJ) Brummer Barbara (Upper Montclair NJ) Dalal Nandita M. (East Brunswick NJ) Toddywala Rohinton (North Brunswick NJ). Antifungal vaginal cream composition. USP1996055514698.
  6. Bayston Roger (London CO GB2) Grove Nancy J. (Conifer CO). Antimicrobial device and method. USP1990044917686.
  7. Igo Stephen R. (Clear Lake Shores TX) Meador James W. (Houston TX). Apparatus and method for transpericardial delivery of fluid. USP1997065634895.
  8. Schutze Detlef-Ingo,DEX ; Thoma Wilhelm,DEX ; Nachtkamp Klaus,DEX ; Pedain Josef,DEX ; Schmitz Reinold,DEX. Aqueous coating compositions and their use for the preparation of coatings that are permeable to water vapor. USP1998055747582.
  9. Schutze Detlef-Ingo,DEX ; Thoma Wilhelm,DEX ; Nachtkamp Klaus,DEX ; Pedain Josef,DEX ; Schmitz Reinold,DEX. Aqueous coating compositions and their use for the preparation of coatings that are permeable to water vapor. USP1998025716676.
  10. McGee John D. ; Campbell Donald H. ; Rehfuss John W.. Aqueous coating compositions for environmental etch resistant coatings. USP1998035726244.
  11. McGee John D. ; Campbell Donald H. ; Rehfuss John W.. Aqueous coating compositions for environmental etch resistant coatings. USP2000036040062.
  12. Hassel Tillmann,DEX ; Meixner Juergen,DEX ; Muenzmay Thomas,DEX ; Reiners Juergen,DEX ; Schoob Jorg,DEX. Aqueous polyurethane dispersions. USP2001096284836.
  13. Miyachi Yasuyoshi (Kanagawa JPX) Ito Nobuo (Kanagawa JPX) Koyama Masako (Kanagawa JPX). Artificial hair from poly amino acid urethane fiber. USP1994025283297.
  14. Smith Kelly L. ; Holmes Matthew F. ; Brooke James W.. Asymmetric microporous beads for controlled release. USP1999035888930.
  15. Yoshida Mitsutoshi (Nagoya JPX) Tsubota Toshio (Nagoya JPX) Okumura Hiroshi (Nagoya JPX). Balance mechanism of an industrial robot. USP1990094954043.
  16. Pacetti, Stephen Dirk; Claude, Charles; Astafieva, Irina. Bioabsorbable, biobeneficial polyurethanes for use in medical devices. USP2010097795467.
  17. Gilis Paul Marie Victor,BEX. Bioadhesive solid dosage form. USP2001106303147.
  18. Leong Kam W. (Ellicott City MD). Biocompatible and biodegradable poly (phosphoester-urethanes). USP1993015176907.
  19. Daniel Goldberg ; Sandra A. Kupperblatt ; Robert F. Eaton ; Wong F Ark ; David M Simpson. Biodegradable lactone copolymers. USP2002026346599.
  20. Woodhouse Kimberly Ann,CAX ; Skarja Gary Alan,CAX. Biodegradable polyurethanes. USP2001046221997.
  21. Ferencz Andreas,DEX ; Huebner Norbert,DEX ; Fischer Herbert,DEX ; Unger Lothar,DEX ; Peters Bernd,DEX ; Mueller Wolf-Ruediger,DEX ; Donothek Horst,DEX ; Kuhn Joerg,DEX. Bonding process. USP2000076093270.
  22. Cournut Rene (Bordeaux-Cauderan FR). Chemically acting intra-uterine device. USP1976013934580.
  23. Place, Virgil A.; Wilson, Leland F.; Doherty, Jr., Paul C.; Hanamoto, Mark S.; Spivack, Alfred P.; Gesundheit, Neil; Bennett, Sean R.. Co-administration of a prostaglandin and an androgenic agent in the treatment of female sexual dysfunction. USP2003076593313.
  24. Matsumoto Yukio (Yokohama JPX) Kunii Nobuaki (Yokohama JPX). Coating composition a non-porous moisture-permeable coating layer or film of a hydrophilic polyurethane resin. USP1990074945149.
  25. Hoefer Rainer (Duessledorf DEX) Gruetzmacher Roland (Wuelfrath DEX) Kaindl Gerhard (Hilden DEX). Coating compositions. USP1994055312865.
  26. McGee John D. ; Bammel Brian D. ; Seaver Todd A. ; Ohrbom Walter H. ; Rehfuss John W. ; Menovcik Gregory G. ; Harris Paul J.. Coating compositions with low molecular weight carbamate or urea component. USP1998125854385.
  27. Simms John A. (Wilmington DE). Coatings containing caprolactone oligomer polyols. USP1992105159047.
  28. Prahl Jan (Rullstorf DEX) Gelbenegger Franz (Hamburg-Volksdorf DEX). Collecting bag for artificial intestinal outlets. USP1982054327727.
  29. Dentler, Joachim; Herfert, Norbert; Klotzsche, Helmut; Schliwa, Rudolf; Stuven, Uwe. Complete drying method for hydrogels. USP2003116641064.
  30. Myhling John. Composition and method for prevention of sexually transmitted diseases, including aids. USP2001126328991.
  31. Lee Clarence C.. Composition and method for revitalizing scar tissue. USP1998065763399.
  32. Lee Clarence C. (Lilburn GA). Composition and method for revitalizing scar tissue. USP1997115686425.
  33. Samour Carlos M. ; Krauser Scott F. ; Gyurik Robert J.. Composition and method for treating penile erectile dysfunction. USP1999085942545.
  34. Lee Robert K. K. ; Wurtman Richard J.. Composition and methods for treatment of neurological disorders and neurodegenerative diseases. USP2001026187756.
  35. Lee Clarence C.. Compositions and method for revitalizing scar tissue. USP1998045739113.
  36. James L. Yeager ; Nadir Buyuktimkin ; Servet Buyuktimkin. Compositions and methods for amelioration of human female sexual dysfunction. USP2002116486207.
  37. Yeager, James L.; Büyüktimkin, Nadir; Büyüktimkin, Servet. Compositions and methods for amelioration of human female sexual dysfunction. USP2004116825234.
  38. Lee Robert K. K. ; Wurtman Richard J.. Compositions and methods for treatment of neurological disorders and neurodegenerative diseases. USP2000036043224.
  39. Lee Robert K. K. ; Wurtman Richard J.. Compositions and methods for treatment of neurological disorders and neurodegenerative diseases. USP2001026184248.
  40. Robert K.K. Lee ; Richard J. Wurtman. Compositions and methods for treatment of neurological disorders and neurodegenerative diseases. USP2002106469055.
  41. Baroody Lloyd J. ; Dow Gordon J. ; Dow Debra A. ; Lathrop Robert. Compositions for the treatment of acne containing clindamycin and benzoyl peroxide. USP2000096117843.
  42. Melman Steven A.. Compositions for treating fungal, parasitic and/or bacterial infections, especially infections of organs such as the ski. USP1998125853767.
  43. Embry Mostyn P. (Woodstock GB3) Graham Neil B. (Bearsden GB6). Controlled release compositions. USP1990014894238.
  44. Embrey Mostyn (Oxford GB2) Graham Neil B. (Dunbartonshire GB6). Controlled release compositions (II). USP1990064931288.
  45. Embrey Mostyn P. (Oxford GB2) Graham Neil B. (Dunbartonshire GB6). Controlled release compositions (II). USP1991055017382.
  46. Embrey Mostyn P. (Oxford GB2) Graham Neil B. (Dunbartonshire GB6). Controlled release compositions including polyethylene oxide with urethane cross-linking. USP1992015079009.
  47. Graham Neil B. (Bearsden GB6) McNeill Marion E. (Milngavie GB6) Wood David A. (Carluke GB6). Controlled release device. USP1989034814182.
  48. Sparks Randall T. (Gainesville GA). Controlled release pharmaceutical formulation. USP1996045505962.
  49. Sparks Randall T. (Gainesville GA) Geoghegan Edward J. (Athlone IEX). Controlled release powder and process for its preparation. USP1990074940588.
  50. Sparks Randall T. (Gainesville GA) Geoghegan Edward J. (Athlone IEX). Controlled release powder and process for its preparation. USP1990084952402.
  51. Sparks Randall T. (Gainesville GA) Geoghegan Edward J. (Westmeath IEX). Controlled release powder and process for its preparation. USP1994105354556.
  52. Runkel, Richard A.; Lee, Jung-Chung. Controlled release subcutaneous implant. USP1991075035891.
  53. Igo Stephen R. (Clear Lake Shores TX) Meador James W. (Houston TX). Coronary vasculature treatment method. USP1997105681278.
  54. Bammel Brian D. ; McGee John D. ; Ohrbom Walter H. ; Seaver Todd A. ; Menovcik Gregory G. ; Harris Paul J. ; Rehfuss John W.. Curable coating composition. USP1998065760127.
  55. Brian D. Bammel ; John D. McGee ; Walter H. Ohrbom ; Todd A. Seaver ; Paul J. Harris ; John W. Rehfuss. Curable coating composition. USP2002076423788.
  56. Ohrbom Walter H. ; Bammel Brian D. ; McGee John D. ; Seaver Todd A. ; Menovcik Gregory G. ; Harris Paul J. ; Rehfuss John W.. Curable coating composition. USP1998105827930.
  57. Menovcik Gregory G. ; McGee John D. ; Ohrbom Walter H. ; Bammel Brian D. ; Seaver Todd A. ; Rehfuss John W.. Curable coating composition including compound having carbamate and hydroxyl functionality. USP1998085792810.
  58. Green Marvin L. ; McGee John D. ; Bammel Brian D. ; Regulski Danielle A. ; Ohrbom Walter H.. Curable coating compositions containing blends of carbamate-functional compounds. USP1999115994479.
  59. Ohrbom Walter H ; Menovcik Gregory G. ; St. Aubin Donald L. ; Boisseau John E. ; Rehfuss John W. ; McGee John D. ; Bammel Brian D. ; Regulski Danielle ; Bradford Christopher. Curable coating compositions containing blends of carbamate-functional compounds. USP2000076084038.
  60. Ohrbom Walter H ; Menovcik Gregory G. ; St. Aubin Donald L. ; Boisseau John E. ; Rehfuss John W. ; McGee John D. ; Bammel Brian D. ; Regulski Danielle ; Bradford Christopher. Curable coating compositions containing blends of carbamate-functional compounds. USP2000066080825.
  61. Ohrbom Walter H. ; Menovcik Gregory G. ; St. Aubin Donald L. ; Boisseau John E. ; Rehfuss John W.. Curable coating compositions containing blends of carbamate-functional compounds. USP2000126160058.
  62. Green Marvin L. ; Rehfuss John W.. Curable coating compositions containing carbamate additive. USP1999025872195.
  63. Menovcik Gregory G. ; Ohrbom Walter H. ; Rehfuss John W.. Curable coating compositions containing carbamate additives. USP1998045744550.
  64. McGee John D. ; Bammel Brian D. ; Ohrbom Walter H. ; Seaver Todd A. ; Menovcik Gregory G. ; Harris Paul J. ; Rehfuss John W.. Curable compositions for coatings. USP1998065770650.
  65. Rehfuss John W. ; Ohrbom Walter H. ; Taylor Robert J.. Curable polyureas. USP2000096114444.
  66. Fildes Francis J. T. (Macclesfield GB2) Hutchinson Francis G. (Macclesfield GB2). Delivery means for biologically active agents. USP1980114235988.
  67. Fildes Francis J. T. (Macclesfield GB2) Hutchinson Francis G. (Lymm GB2). Delivery means for biologically active agents comprising hydrophilic polyurethane. USP1980054202880.
  68. Wong Patrick S. L. (Palo Alto CA) Pharriss Bruce B. (Palo Alto CA). Delivery system with mated members for storing and releasing a plurality of beneficial agents. USP1980124237885.
  69. Merida A. D'Augustine ; James H. Liu ; Donald C. Harrison. Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections. USP2002076416779.
  70. Harrison Donald C. ; Liu James H. ; Ritschel Wolfgang A. ; Stern Roger A.. Device and method for treatment of dysmenorrhea. USP2001036197327.
  71. Harrison Donald C. ; Liu James H. ; Ritschel Wolfgang A. ; Stern Roger A.. Device and method for treatment of dysmenorrhea. USP2000076086909.
  72. Wong Patrick S. (Hayward CA). Device for delivering agent in vagina. USP1983094402695.
  73. Graham Neil B. (Bearsden GBX) Huehns Ernst R. (London GBX) McNeill Marion E. (Milngavie GBX). Device for sustained release of active substance. USP1990114973304.
  74. Zaffaroni Alejandro (Atherton CA). Drug delivery device. USP1976073967618.
  75. Norton Peter (4787 Woodworth Dearborn MI 48126). Dual voltage power supply system for vehicles. USP1987094694238.
  76. Alam Rafeul (14910 Wilderness Cliff Houston TX 77062) Grant J. Andrew (2914 Beluche St. Galveston TX 77551). Effects of misoprostol on allergic responses. USP1993105252602.
  77. Gertzmann, Rolf; Schmalstieg, Lutz; Mazanek, Jan; Hausstatter, Bernd. Electrical insulating enamel binders having a urea and/or hydantoin structure. USP2003016512073.
  78. Sarangapani Shantha (Walpole MA). Encrusting and bacterial resistant coatings for medical applications. USP1994075328954.
  79. Deckner George Endel ; Lombardo Brian Scott. Enhanced skin penetration system for improved topical delivery of drugs. USP1998075780049.
  80. Brodbeck Kevin J. ; Gaynor-Duarte Ann T. ; Shen Theodore Tao-Ian. Gel composition and methods. USP2000106130200.
  81. Schpel Dietmar (Cologne DE). Gel compositions with depot action based on a polyurethane matrix and relatively high molecular weight polyols and conta. USP1983094404296.
  82. Dewanjee, Pijush K.. Golf ball having a non-yellowing cover. USP2003076592472.
  83. Dewanjee Pijush K.. Golf ball with polyurethane cover. USP2000096117024.
  84. Dewanjee, Pijush K.. Golf ball with polyurethane cover. USP2003016511388.
  85. Tipton Arthur J. ; Holl Richard J.. High viscosity liquid controlled delivery system. USP1998055747058.
  86. Gibson, John W.; Miller, Stacey S.; Middleton, John C.; Tipton, Arthur J.. High viscosity liquid controlled delivery system and medical or surgical device. USP2010117833543.
  87. Gibson,John W.; Tipton,Arthur J.. High viscosity liquid controlled delivery system and medical or surgical device. USP2006057053209.
  88. John W. Gibson ; Stacey A. Sullivan ; John C. Middleton ; Arthur J. Tipton. High viscosity liquid controlled delivery system and medical or surgical device. USP2002076413536.
  89. Tipton Arthur J.. High viscosity liquid controlled delivery system as a device. USP1999105968542.
  90. Fujiwa Takaaki (Hiroshima JPX). Hydrolysis resistant polyurethane resins. USP1992055116932.
  91. Reich Murray H. ; Nelson Ken. Hydrophilic polyether polyurethanes containing carboxylic acid. USP2000106130309.
  92. Szycher Michael (Lynnfield MA). Hydrophilic polyurethane elastomers. USP1992065118779.
  93. Allen Douglas J. (Indianapolis IN) Johnson Kirk W. (Indianapolis IN) Nevin Robert S. (Indianapolis IN). Hydrophilic polyurethane membranes for electrochemical glucose sensors. USP1994065322063.
  94. Fagerburg David R. (Kingsport TN) Jackson ; Jr. Winston J. (Kingsport TN). Hydroxyl-terminated polyether-esters. USP1985034503216.
  95. Tanigami Hajime (Osaka JPX) Mashima Hiroshi (Chiba JPX) Ozaki Makoto (Kanagawa JPX). Impact-resistant composition. USP1996115574102.
  96. Seeger Nelson V. (Cuyahoga Falls OH) Kaman Andrew J. (Norton OH). Impact-resistant thermoplastic polyester urethanes. USP1976013931113.
  97. Plummer, Thomas L.; Comes, Val C.; Wallace, George R.. Injection-moldable thermoplastic polyurethane elastomer. USP2003026521164.
  98. Shalaby, Shalaby W.. Interlinked solid polyethylene glycols and copolymers thereof. USP2005036861503.
  99. Kwan Lilian (Saint Davids PA) Steber William (Ledgewood NJ). Intermittent release dosage form. USP1992055110598.
  100. Kwan Lilian (Saint Davids PA) Steber William (Ledgewood NJ). Intermittent release dosage form. USP1993015178874.
  101. Lorraine Elisabeth Pena ; Phil Bryan Bowman ; Robert Shih-Liang Chao ; Carolyn V. Pesheck. Intravaginal clindamycin ovule composition. USP2002126495157.
  102. Brodman Michael L. (Great Neck NY) Kirschbaum Warren (Kemah TX) Weinberg Steven L. (League City TX). Intravaginal device and method for delivering a medicament. USP1991035002540.
  103. Nabahi Shohre,GBX. Intravaginal drug delivery device. USP2000036039968.
  104. Nabahi Shohre,GBX. Intravaginal drug delivery device. USP2000086103256.
  105. McClay Allen,IEX. Intravaginal drug delivery devices for the administration of 17.beta.-oestradiol precursors. USP1999015855906.
  106. Saleh Saleh Ismail,EGX ; Nash Harold A. ; Bardin C. Wayne ; Harmon Troy. Intravaginal rings with insertable drug-containing core. USP2000106126958.
  107. Saleh Saleh Ismail,EGX ; Nash Harold A. ; Bardin C. Wayne ; Harmon Troy. Intravaginal rings with insertable drug-containing core. USP1999105972372.
  108. Watanabe, Shoji; Miho, Takuya; Fujii, Tatsumi. Lactone polymer. USP1983044379915.
  109. Nishimura Takeo (Okayama JPX). Leather-like sheet materials and method of producing same. USP1992105156900.
  110. Flodin Per,SEX. Linear block polymer comprising urea and urethane groups, method for the production of linear block polymers and use of the block polymers as implants. USP2001046210441.
  111. Koleske Joseph V. (Charleston WV) Smith Oliver W. (South Charleston WV) France Haywood G. (South Charleston WV) Taller Robert A. (Charleston WV). Low-energy-curable coatings compositions. USP1981064276405.
  112. Kizumoto, Hirotoshi; Yatsuka, Takeshi; Sugitawa, Chikara; Doi, Kuniyuki. Magnetic recording media and thermoplastic polyurethane resins therefor. USP2003046545119.
  113. Kohno Kenji (Nagaokakyo JPX) Nagataki Yoshiyuki (Osaka JPX) Miyata Kazushi (Osaka JPX) Higashi Hiroshi (Osaka JPX). Magnetic recording medium having a magnetic layer formed from an aromatic polycarbonate polyurethane resin. USP1993065219663.
  114. Kock Nils G.,SEX ; Lycke Gerhard,SEX. Method and composition for treating erectile dysfunction. USP1999085942512.
  115. Kock Nils G.,SEX ; Lycke Gerhard,SEX. Method and composition for treating erectile dysfunction. USP1998125843961.
  116. Kock Nils G.,SEX ; Lycke Gerhard,SEX. Method and composition for treating erectile dysfunction. USP1999035886039.
  117. Abend Thomas P.,CHX. Method and material mixture for manufacture of reactive hotmelts. USP1998015710215.
  118. Volkmann, Peter-Hansen. Method for administering a vaginal care composition. USP2010037670606.
  119. Zaffaroni ; Alejandro ; Michaels ; Alan S. ; Theeuwes ; Felix. Method for administering drug to the gastrointestinal tract. USP1978064096238.
  120. Wysor Michael S. ; Wysor Wanda D.. Method for enhancing female sexual response and a composition therefor. USP2000026031002.
  121. Wysor Michael S. ; Wysor Wanda D.. Method for enhancing female sexual response and an ointment therefor. USP1999045891915.
  122. Burke Paul A.. Method for fabricating polymer-based controlled-release devices. USP1998105817343.
  123. English James P. (Birmingham AL) McNeely Gerald W. (Spartanburg SC) Dunn Richard L. (Birmingham AL). Method for making a biodegradable adhesive for soft living tissue. USP1989024804691.
  124. Virgil A. Place ; Leland F. Wilson ; Paul C. Doherty, Jr. ; Mark S. Hanamoto ; Alfred P. Spivack ; Neil Gesundheit ; Sean R. Bennett. Method for minimizing excess collagen deposition. USP2002106472434.
  125. Ohrbom Walter H. ; Campbell Donald H. ; St. Aubin Donald L.. Method for modified aminoplast compounds, aminoplasts obtained thereby and coatings containing the same. USP1998075777048.
  126. Shirasaka Hitoshi,JPX. Method for preparing amorphous polymer chains in elastomers. USP2000086103852.
  127. Matsumoto, Yasuhiro; Takeuchi, Hideyuki; Tanaka, Hiroki. Method for producing liquid urethane prepolymer and resin composition. USP2003106632913.
  128. Shirasaka Hitoshi,JPX. Method for producing millable polyurethanes and polyurethane elastomers. USP1999126008312.
  129. Glenn E. Myles (Kalamazoo MI). Method for treating inflammation. USP1981094289757.
  130. Short George E. (Arlington Heights IL). Method for use of 11-lower alkyl steroids. USP1976033941880.
  131. Pijush K. Dewanjee. Method of fabricating a golf ball with polyurethane cover. USP2002116482345.
  132. McKee Rex N. (2368 Mill Rd. Traer IA 50675) Wingrove Frank A. (1029 Sunrise Blvd. Waterloo IA 50701). Method of treating damaged mucosal and epithelial tissues with misoprostol. USP1994065324746.
  133. McKee Rex N. (2368 Mill Rd. Traer IA 50675) Wingrove Frank A. (1029 Sunrise Blvd. Waterloo IA 50701). Method of treating damaged mucosal and epithelial tissues with misoprostol. USP1996045510384.
  134. Kock Nils G.,SEX ; Lycke Gerhard,SEX. Method of treating erectile dysfunction with nitroglycerine. USP1998125849803.
  135. Bartning, Michelle; Gironda, Kevin F.; Hou, Mari; Luchino, Thomas P.; Luehrs, Kirsten Freislinger; Mavinkurve, Pramod; Rosenfeld, Leonard; Hull, Jr., Raymond J.; Chase, David J.. Method of treating urinary incontinence. USP2010057717892.
  136. Bartning, Michelle; Gironda, Kevin F.; Hou, Mari; Luchino, Thomas P.; Luehrs, Kirsten Freislinger; Mavinkurve, Pramod; Rosenfeld, Leonard; Hull, Jr., Raymond J.; Chase, David J.. Method of treating urinary incontinence. USP2011027892163.
  137. Frolich Jurgen C. (Rohrichtweg 11 3000 Hannover 71 DEX) Bippi Herbert (Wolfratshauser Strasse 35 8032 Pullach DEX). Method of treatment of impotence with prostaglandin E1 derivatives. USP1997105681850.
  138. Kanakaris, Panagiotis; Karouzakis, Petros. Methods and compositions for misoprostol compound treatment of erectile dysfunction. USP2003076589990.
  139. Neal, Gary W.. Methods and compositions for preventing and treating prostate disorders. USP2003116642274.
  140. Gary W. Neal. Methods and compositions for treating male erectile dysfunction. USP2002076414027.
  141. Gary W. Neal. Methods and compositions for treating male erectile dysfunction. USP2002066410595.
  142. Neal, Gary W.. Methods and compositions for treating male erectile dysfunction. USP2003056559184.
  143. Ron, Eyal S.; Langer, Robert S.; Crowley, Jr., William F.. Methods and devices for the sustained release of multiple drugs. USP2010117829112.
  144. Ron, Eyal S.; Langer, Robert S.; Crowley, Jr., William F.. Methods and devices for the sustained release of multiple drugs. USP2010117833545.
  145. Ron, Eyal S.; Langer, Robert S.; Crowley, Jr., William F.. Methods and devices for the sustained release of multiple drugs. USP2011027883718.
  146. Ron, Eyal S.; Langer, Robert S.; Crowley, Jr., William F.. Methods and devices for the sustained release of multiple drugs. USP2010117838024.
  147. Neal Gary W.. Methods for treating male erectile dysfunction. USP2000086103765.
  148. Luo Ming. Methods of inhibiting bacterial sialidase. USP1999115985859.
  149. Fritz Hostettler ; Peter Wachtel. Methods of preparing polyurethane adhesives, adhesives produced thereby and medical devices employing the same. USP2002036359100.
  150. Bockman Richard S. (22 Spring St. Sag Harbor NY 11963). Methods of protecting and preserving connective and support tissues. USP1994055310759.
  151. Neal, Gary W.. Methods, compositions, and kits for enhancing female sexual desire and responsiveness. USP2003076593369.
  152. Ishii Seiji (Yokohama JPX) Miyoshi Masanori (Yokohama JPX) Ishiwaka Takumi (Yokohama JPX) Kondo Osamu (Yokohama JPX). Microcellular polyurethane elastomer and manufacturing method of the same. USP1987034647596.
  153. Graham Neil Bonnette,GBX ; Mao Jianwen,DEX. Microgels. USP1999115994492.
  154. Zaffaroni Alejandro (Atherton CA). Microporous drug delivery device. USP1976113993072.
  155. Krebs Michael,DEX ; Heider Roland,DEX ; Schillings Klaus,DEX ; Gansow Michael. Moisture curing polyurethane hot-melt adhesive. USP1999105965662.
  156. Zenda Tatsuya (Ishikawa JPX) Hayashi Yutaka (Ishikawa JPX) Kitagawa Motoaki (Hikone JPX) Seino Takashi (Shiga JPX). Moisture-permeable waterproof fabric and process for production thereof. USP1994075326632.
  157. Del Soldato, Piero; Benedini, F{overscore (r)}ancesca; Antognazza, Patrizia. Nitrate salts of antimicrobial agents. USP2004096794372.
  158. Zaffaroni Alejandro (Atherton CA). Novel drug delivery device. USP1976043948254.
  159. Zaffaroni Alejandro (Atherton CA). Novel drug delivery device. USP1976113993073.
  160. Zaffaroni Alejandro (Atherton CA). Novel drug delivery device. USP1976043948262.
  161. El-Rafaey, Hazem. Oral or vaginal administration of mesoprostol in third stage labor. USP2003126664290.
  162. Janet Anne Halliday GB; Steven Robertson GB. Oral transmucosal delivery. USP2002126488953.
  163. Higuchi Takeru (Lawrence KS) Leeper Harold M. (Mountain View CA). Osmotic dispenser with means for dispensing active agent responsive to osmotic gradient. USP1976123995631.
  164. Zaffaroni ; Alejandro ; Michaels ; Alan S. ; Theeuwes ; Felix. Osmotic releasing device having a plurality of release rate patterns. USP1978064093708.
  165. Zaffaroni Alejandro (Atherton CA) Michaels Alan S. (Atherton CA) Theeuwes Felix (Los Altos CA). Osmotic releasing device having a plurality of release rate patterns. USP1977074036227.
  166. Zaffaroni Alejandro (Atherton CA) Michaels Alan S. (Atherton CA) Theeuwes Felix (Los Altos CA). Osmotic releasing system for administering ophthalmic drug to eye of animal. USP1979014135514.
  167. Zaffaroni Alejandro (Atherton CA) Michaels Alan S. (San Francisco CA) Theeuwes Felix (Los Altos CA). Osmotic releasing system with means for changing release therefrom. USP1979034142526.
  168. Higuchi Takeru (Lawrence KS) Leeper Harold M. (Mountain View CA). Osmotically driven fluid dispenser. USP1977074034756.
  169. Yoshikawa Hirofumi,JPX ; Sasaki Hideki,JPX ; Seki Junzo,JPX. PGE.sub.1 -containing-freeze dried preparation and process for the production thereof. USP1999115977172.
  170. Rosenthale Marvin E. (Princeton NJ) Shriver David A. (Martinsville NJ) Katz Laurence B. (Lawrenceville NJ). Peptic ulcer treatment method. USP1987114707495.
  171. Samuel J. Tremont ; Denis Forster ; Ricky L. Fenton ; Yinong Ma. Ph-selective delivery system using crosslinked polymeric resins as vehicles. USP2002106471955.
  172. Vulpescu, Dan-Gabriel; Freudensprung, Brigitte. Pharmaceutical composition. USP2003036537970.
  173. Prisell Per (Wollmar Yxkullsgatan 15A S-116 50 Stockholm SEX) Norstedt Gunnar (Foerfattavaegen 46 S-116 42 Bromma SEX). Pharmaceutical preparation. USP1995115470829.
  174. Kwee Bobby L. S. (JV OSS NLX) Egberink Johannes G. J. (EB OSS NLX). Pharmaceutical preparation for obtaining a highly viscose hydrogel or suspension. USP1989044818517.
  175. Hisayuki Kayanoki JP; Fujio Sawaragi JP. Plastic lenses and primer composition used for coating the same. USP2002086440568.
  176. Tremont Samuel J.. Polyamines and method for preparation thereof. USP1998085795567.
  177. Tremont Samuel J. (Manchester MO). Polyamines and method for preparation thereof. USP1997125693319.
  178. Tremont Samuel J. (Manchester MO). Polyamines and method for preparation thereof. USP1997105676939.
  179. Tremont Samuel J. (Manchester MO). Polyamines and method for preparation thereof. USP1995125474767.
  180. Kohno Kenji (Nagaokakyo JPX) Nagataki Yoshiyuki (Osaka JPX) Miyata Kazushi (Osaka JPX) Higashi Hiroshi (Osaka JPX). Polycarbonate polyol, aromatic polycarbonate polyurethane resin, coating agent, cast film, magnetic recording medium. USP1991095045622.
  181. Piccirilli Robert M. (Pittsburgh PA) Chang Wen-Hsuan (Gibsonia PA) McKeough David T. (Gibsonia PA) Porter ; Jr. Samuel (Natrona Heights PA). Polyester coating composition. USP1980054205115.
  182. Peerman Dwight (Minnetonka MN). Polyester polyols from bishydroxymethyl tricyclo compounds and caprolactone and polyurethanes based thereon. USP1984034438225.
  183. Koyama Yoshiyuki (Noda JPX) Kojima Shuji (Kashiwa JPX) Miyazaki Tsuyoshi (Tsukuba JPX) Suginaka Akinori (Chigasaki JPX) Matsumoto Takeo (Tsukuba JPX) Murata Yoshishige (Tsukuba JPX). Polymer-drug conjugate and a method of producing it. USP1992075130126.
  184. Tremont Samuel J. ; Collins Paul Waddell ; Perkins William Eldredge ; Jones Peter Hadley. Polymeric drug delivery system. USP1998105827925.
  185. Lee Jung-Chung ; Pushpala Shamim ; Lee Charles E.. Polymeric microporous film coated subcutaneous implant. USP2000026022554.
  186. Hoy Kenneth L. (St. Albans WV) Hoy Richard C. (South Charleston WV). Polymers with hydrophobe bunches. USP1984014426485.
  187. Watanabe Shoji (Ohtake JPX) Miho Takuya (Ohtake JPX). Polyurethane. USP1984054447591.
  188. Moeller, Thomas; Gensch, Ingo; Fischer, Herbert; Huebner, Norbert; Plum, Hermann-Josef; Herlfterkamp, Bernhard. Polyurethane adhesive. USP2003106630050.
  189. Bailey ; Brian Edward ; Bunker ; Anthony John. Polyurethane adhesives having high peel strength at 70.degree. C. USP1978074098747.
  190. Muhlfeld, Horst; Wagener, Silke. Polyurethane molding mass that can be processed thermoplastically. USP2003076586553.
  191. Menovcik Gregory L. (Farmington Hills MI) Ohrbom Walter H. (Commerce MI). Polyurethane polymer or oligomer having carbamate groups, method for its preparation, and coating composition. USP1997085659003.
  192. Menovcik Gregory L. ; Ohrbom Walter H.. Polyurethane polymer or oligomer having carbamate groups, method for its preparation, and coating composition. USP1998035723552.
  193. Menovcik Gregory L. ; Ohrbom Walter H.. Polyurethane polymer or oligomer having carbamate groups, method for its preparation, and coating composition. USP1998035726274.
  194. Menovcik Gregory L. ; Ohrbom Walter H.. Polyurethane polymer or oligomer having carbamate groups, method for its preparation, and coating composition. USP1998105827931.
  195. Julia Barges Joaquim,ESX ; Ayuso Piqueras Jose Luis,ESX. Polyurethane thermoplastic material and production process. USP2000106140453.
  196. Fisch Herbert (Wachenheim DEX) Maempel Lothar (Bruehl DEX) Volkert Otto (Weisenheim DEX). Preparation of emulsifier-free aqueous polyurethane dispersions. USP1991105055516.
  197. Matsumoto Yukio (Yokohama JPX) Kunii Nobuaki (Yokohama JPX). Prepolymer composition utilizing polyol combination for production of coatings and films. USP1991095049638.
  198. Wong Patrick S. (Palo Alto CA). Process for making drug delivery device with reservoir. USP1981024250611.
  199. Kondo Kanemitu (Okazaki JPX) Nomura Takao (Toyota JPX) Ukai Junzo (Toyota JPX) Isaka Takuji (Kyoto JPX) Ishikawa Isao (Kyoto JPX) Nagata Kouzaburo (Kyoto JPX). Process for producing polyurethane. USP1992035100926.
  200. Matier William L. (Hockessin DE) Woo Chi (Libertyville IL) Lee Ying-Chi (Libertyville IL). Process for the preparation of clindamycin phosphate. USP1990014895934.
  201. Schpel Dieter (Cologne DEX). Production of molds using gel compositions with depot action based on a polyurethane matrix and relatively high molecula. USP1984084466936.
  202. Gass Bruno,CAX. Projection welded panel spacer and method for making the same. USP2001026188039.
  203. Gass, Bruno. Projection welded panel spacer and method for making the same. USP2003046543828.
  204. Frlich Jrgen (Rhrichtweg 11 3000 Hannover 71 DEX) Bippi Herbert (Wolfratshauser Str. 35 8032 Pullach DEX). Prostaglandin E1 derivatives as pharmaceutically active agents, and pharmaceutical compositions containing these compoun. USP1993065219885.
  205. Frolich Jurgen C.,DEX ; Bippi Herbert,DEX. Prostaglandin E1 derivatives as pharmacologically active agents, especially for transcutaneous administration. USP1999105973002.
  206. Frlich Jrgen C. (Rhrichtweg 11 3000 Hannover 71 DEX) Bippi Herbert (Warburghof 10B 3000 Hannover 61 DEX). Prostaglandin E1 derivatives for transdermal administration and methods of treatment therewith. USP1995115464868.
  207. Yeager James L. ; Buyuktimkin Nadir ; Buyuktimkin Servet. Prostaglandin compositions and methods of treatment for male erectile dysfunction. USP2001116323241.
  208. Yeager, James L.; Buyuktimkin, Nadir; Buyuktimkin, Servet. Prostaglandin compositions and methods of treatment for male erectile dysfunction. USP2004026693135.
  209. Hanson Wayne R. (Oak Park IL). Protective prostaglandins for use in conjunction with chemotherapeutic agents. USP1996115578643.
  210. Hanson Wayne R. (Oak Park IL). Protective prostaglandins for use in conjunction with chemotherapeutic agents. USP1997025605931.
  211. Hanson Wayne R. (Oak Park IL). Protective prostaglandins for use in conjunction with chemotherapeutic agents. USP1996115578640.
  212. Mller Hanns-Peter (Odenthal DEX) Dhein Rolf (Krefeld DEX) Hugl Herbert (Bergisch Gladbach DEX) Pudleiner Heinz (Krefeld DEX). Pure, in particular catalyst-free polyurethanes. USP1994125374704.
  213. Park Kisoon (Charleston WV). Radiation-curable allyl- or vinyl capped polycaprolactone compositions. USP1981044264757.
  214. Stobbie ; IV Charles W. (Woodbury MN) Tangen John C. (St. Paul MN). Reactive wax-containing moisture curable hot melt composition. USP1995125472785.
  215. Burns Patrick J.. Regulation of estrus and ovulation in gilts. USP2000026028057.
  216. de Nijs Henrik (Oss NLX). Release system for two or more active substances. USP1986064596576.
  217. Quigley ; Jr. John W. (Foster City CA) Goodman Harris (San Francisco CA). Retinoic acid-containing compositions. USP1997125700483.
  218. Quigley ; Jr. John W. (Foster City CA) Goodman Harris (San Francisco CA). Retinoic acid-containing polyether-polyurethane compositions. USP1997075650171.
  219. MacDonald Ishbel A. (Glasgow GB6) Muddle Andrew G. (Strathaven GB6) MacFarlane Lindesay R. (Glasgow GB6). Retrievable pessary. USP1993125269321.
  220. Thomas Heinrich Sieker DE; Franco Gabrieli IT; Saskia Rachel Walraedt BE. Rigid polyurethane foams. USP2002066403665.
  221. Oriani Steven R. (Houston TX). Rigid thermoplastic plyurethane comprising units of butane diol and a polyethylene glycol. USP1997055627254.
  222. Kawata Terushige (Tokushima JPX) Yamashita Shinsuke (Tokushima JPX). Sheet-shape adhesive preparation. USP1988084767787.
  223. Kawata Terushige (Tokushima JPX) Yamashita Shinsuke (Tokushima JPX). Sheet-shape adhesive preparation. USP1986064594240.
  224. Kararli Tugrul T. ; Otto David ; Penzotti ; Jr. Stanley C. ; Truelove James E.. Stabilized dispersions of misoprostol. USP1999085935939.
  225. Wagner Julie Ann ; Zukowski Joseph Michael ; Robinson Larry Richard ; Deckner George Endel ; Rinaldi Marie Antoinette ; Szymanski Victoria Claire. Stable topical compositions. USP1999095948416.
  226. Sterrett Terry L. (Long Beach CA). Stain-resistant orthodontic device. USP1990064933418.
  227. Beckett, Christian Westy; Eliasen, Per Robert Topp. Suppository and composition comprising at least one polyethylene glycol. USP2004056740333.
  228. Riffle Judy S.. Surface-modifying copolymers having cell adhesion properties. USP1998035733538.
  229. Damani Nalinkant C. (Cincinnati OH). Sustained release compositions for treating periodontol disease. USP1992055114718.
  230. Friedman Michael,ILX ; Kohen Ron,ILX. Sustained-release pharmaceutical system for the delivery of antioxidants. USP1999045897879.
  231. Livingston Douglas A. (Kalamazoo MI). Synthesis of 7-halo-7-deoxylincomycins. USP1986024568741.
  232. Martin Alain (31 Country Club Dr. Ringoes NJ 08551). Therapeutic-wound healing compositions and methods for preparing and using same. USP1997075652274.
  233. Gould Francis E. (Princeton) Johnston Christian W. (Neshanic Station) Seems George E. (Pennington NJ). Thermally reversible polyurethane hydrogels and cosmetic, biological and medical uses. USP1991035000955.
  234. Karakelle Mutlu (Dayton OH) Solomon Donald D. (Spring Valley OH). Thermoplastic elastomeric hydrophilic polyetherurethane expandable catheter. USP1991105061254.
  235. Pudleiner Heinz,DEX ; Dujardin Ralf ; Hobler Hartwin,DEX. Thermoplastic polyurethanes containing active substances. USP2000116150489.
  236. Dewanjee, Pijush K.. Thermosetting polyurethane material for a golf ball. USP2003086607686.
  237. Ayer Donald E. (Kalamazoo MI) Schlagel Carl A. (Kalamazoo MI) Flynn Gordon L. (Ann Arbor MI). Topical clindamycin preparations. USP1977044018918.
  238. Servet Buyuktimkin ; Nadir Buyuktimkin ; James L. Yeager. Topical compositions containing prostaglandin E1. USP2002076414028.
  239. Buyuktimkin Servet ; Buyuktimkin Nadir ; Yeager James. Topical compositions for prostaglandin E.sub.1 delivery. USP2000046046244.
  240. Mo, Y. Joseph; Frank, Daniel W.. Topical stabilized prostaglandin E compound dosage forms. USP2005016841574.
  241. Hsieh Dean. Transdermal and trans-membrane delivery compositions. USP1998035731303.
  242. Hseih Dean (Brandamore PA). Transdermal and trans-membrane delivery of drugs. USP1991065023252.
  243. Seeger Nelson V. (Cuyahoga Falls OH) Kaman Andrew J. (Norton OH). Transparent, impact-resistant polyesterurethane laminates. USP1977084041208.
  244. Place Virgil A. ; Wilson Leland F. ; Doherty ; Jr. Paul C. ; Hanamoto Mark S. ; Spivack Alfred P. ; Gesundheit Neil ; Bennett Sean R.. Treatment of female sexual dysfunction. USP2001106306841.
  245. Place Virgil A. ; Wilson Leland F. ; Doherty ; Jr. Paul C. ; Hanamoto Mark S. ; Spivack Alfred P. ; Gesundheit Neil ; Bennett Sean R.. Treatment of female sexual dysfunction. USP2001096294550.
  246. Place Virgil A. ; Wilson Leland F. ; Doherty ; Jr. Paul C. ; Hanamoto Mark S. ; Spivack Alfred P. ; Gesundheit Neil ; Bennett Sean R.. Treatment of female sexual dysfunction. USP1999035877216.
  247. Virgil A. Place ; Leland F. Wilson ; Paul C. Doherty, Jr. ; Mark S. Hanamoto ; Alfred P. Spivack ; Neil Gesundheit ; Sean R. Bennett. Treatment of female sexual dysfunction using phosphodiesterase inhibitors. USP2002106469016.
  248. Pascault Jean Pierre (Villeurbanne FRX) Cuve Lon (Lyon FRX). Urethane polymer composition and preparation of articles from these polymers. USP1991105057573.
  249. Joseph William D. ; Pavelka Lee A.. Urethane/acrylate bead bond for retroreflective articles. USP1999095959775.
  250. Son Nguyen Kim DE; Axel Sanner DE; Karin Sperling-Vietmeier DE; Peter Hoessel DE. Use of cationic polyurethanes and polyureas as ingredients of cosmetic preparations. USP2002016335003.
  251. Kanakaris Panagiotis,GRX ; Karouzakis Petros,GRX. Use of misoprostol or/and misoprostol acid for diagnosis of vascular damage in a subject with erectile dysfunction. USP2001046210343.
  252. Leonardi Amedeo,ITX ; Motta Gianni,ITX ; Testa Rodolfo,ITX ; Sironi Giorgio,ITX. Use of selective antagonists of the .alpha.1B-adrenergic receptor for improvement of sexual dysfunction. USP2001106303606.
  253. Leonardi, Amedeo; Motta, Gianni; Testa, Rodolfo; Sironi, Giorgio. Use of selective antagonists of the α1B-adrenergic receptor for improvement of sexual dysfunction. USP2005106953800.
  254. Kim Son Nguyen,DEX ; Sanner Axel,DEX ; Kolter Karl,DEX. Use of water-soluble or water-dispersible polyurethanes as coatings or binders for pharmaceutical presentations. USP2000096123963.
  255. Wong Patrick S. (Palo Alto CA). Vaginal contraceptive system made from block copolymer. USP1980084215691.
  256. Harrison, Donald C.; Liu, James H.; Pauletti, Giovanni M.; Ritschel, Wolfgang A.. Vaginal delivery of bisphosphonates. USP2003066572874.
  257. Wong Patrick S. (Kowloon HKX). Vaginal drug delivery system made from polymer. USP1981094286587.
  258. Villanueva,Julie M.. Vaginal health products. USP2007027179481.
  259. Villanueva,Julie M.; Malik,Sohail. Vaginal health products. USP2009027485666.
  260. Myhling John (Rhinebeck NY). Vaginal sponge delivery system. USP1996065527534.
  261. Igo Stephen R. ; Meador James W.. Vascular treatment method and apparatus. USP1999055900433.
  262. Spijkers, Jozef C. W.; Van De Ven, Hendricus J. M.; Mezger, Thomas; Bontinck, Dirk; De Koninck, Luc. Water vapor permeable thermoplastic polyurethane film. USP2004096790926.
  263. Kim,Son Nguyen; Sanner,Axel; H철ssel,Peter. Water-soluble or water-dispersible graft polymers, their preparation and use. USP2006016992161.

이 특허를 인용한 특허 피인용횟수: 2

  1. Tuominen, Jukka; Zurutuza, Amaia; Livingstone, Mark Alexander; Halliday, Janet Anne. Hydrophilic polyurethane compositions. USP20181010105445.
  2. Halliday, Janet Anne; Tuominen, Jukka; Livingstone, Mark Alexander; Koppenhagen, Frank; Currie, Lilias Morton; Stewart, Sarah. Water-swellable polymers. USP2018069987364.

IPC 상위 출원인