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A system for storing biopharmaceutical materials includes a plurality of flexible walls bounding an interior for holding biopharmaceutical materials therein. At least one port is connected to a first wall of the walls and provides fluid communication between the interior and an exterior to allow a d

A system for storing biopharmaceutical materials includes a plurality of flexible walls bounding an interior for holding biopharmaceutical materials therein. At least one port is connected to a first wall of the walls and provides fluid communication between the interior and an exterior to allow a draining of the interior. A collapsible conduit includes a plurality of perforations along the conduit. The plurality of perforations is configured to allow flow of the biopharmaceutical materials from the exterior to the interior of the conduit. The conduit has a cross-sectional area transverse to a length of the conduit and the conduit extends from one of the at least one port toward an opposite end of the interior. The conduit is collapsible by the flexible walls and forms a reduced cross-sectional area to allow a flow of the biopharmaceutical materials through and/or along the conduit to the port.

대표청구항 ▼

1. A system for storing biopharmaceutical materials, said system comprising: a plurality of flexible walls bounding an interior of a container for holding biopharmaceutical materials therein;at least one port connected to a first wall of said walls and providing fluid communication between said inte

1. A system for storing biopharmaceutical materials, said system comprising: a plurality of flexible walls bounding an interior of a container for holding biopharmaceutical materials therein;at least one port connected to a first wall of said walls and providing fluid communication between said interior and an exterior to allow a draining of said interior; anda collapsible conduit having a plurality of perforations along said conduit, said plurality of perforations configured to allow a flow of the biopharmaceutical materials from the exterior to the interior of said conduit;said conduit having a cross sectional area transverse to a length of said conduit, and said conduit extending from one of said at least one port toward an opposite end of said interior;said conduit being collapsible by said flexible walls and forming a reduced cross sectional area when said container is drained to allow a flow of the biopharmaceutical materials through and/or along said conduit to said portsaid conduit comprising a first interior surface facing a second interior surface about an interior of said conduit, said first surface and said second surface contacting each other across a width of said conduit upon being flattened by the draining of said container, the flattening of the conduit minimizing a hold up volume of the conduit. 2. The system of claim 1 wherein said conduit is connected to said first wall. 3. The system of claim 1 wherein an entire length of said conduit is connected to said first wall. 4. The system of claim 1 further comprising a second wall of said walls opposite said first wall about said at least one port, said conduit connected to said second wall. 5. The system of claim 1 wherein said conduit directly contacts said first wall and a second wall of said plurality of walls such that a passage for a flow of the biopharmaceutical materials is provided between said first wall and said second wall. 6. The system of claim 1 wherein said conduit consists of a nonwoven mesh. 7. The system of claim 1 wherein said conduit consists of a mesh cylinder. 8. The system of claim 1 wherein said conduit consists of a flattened mesh cylinder. 9. The system of claim 1 wherein said conduit is more rigid than said first wall. 10. The system of claim 1 wherein said conduit consists of a first mesh cylinder located axially within a second mesh cylinder. 11. The system of claim 1 wherein said conduit consists of a mesh cylinder, said conduit flattened and folded along a longitudinal dimension of said conduit such that four layers of said conduit are located such that a bottom layer contacts said container, a second layer contacts said bottom layer, a third layer contacts said second layer, and a top layer contacts said third layer. 12. The system of claim 1 further comprising a probe located in said at least one port, said probe configured to measure at least one characteristic of said interior of said container. 13. A method for removing biopharmaceutical materials from a flexible container, the method comprising: pumping the biopharmaceutical materials through and/or along a collapsible conduit in an interior of the flexible container to a port of the flexible container, the port providing fluid communication between the interior of the flexible container and an exterior of the flexible container; a plurality of perforations of the collapsible conduit allowing flow of the biopharmaceutical materials from an exterior to an interior of the conduit; andthe conduit extending from the port toward an opposite end of the interior;a first interior surface of the conduit facing a second interior surface of the conduit about an interior of the conduit, the pumping causing the conduit to collapse such that the conduit is flattened and the first surface and the second surface contact each other across a width of the conduit to minimize a hold up volume of the conduit. 14. The method of claim 13 wherein the conduit comprises a plurality of perforations along the length of the conduit and further comprising causing flow through the plurality of perforations by the pumping. 15. The method of claim 13 wherein the collapsible conduit comprises a cylindrical mesh and further comprising collapsing the conduit by the pumping to form a collapsed cylindrical mesh. 16. The method of claim 13 wherein the collapsible conduit comprises a first circumferential internal surface and a second circumferential internal surface and wherein the pumping causes the collapsible conduit to collapse to cause the first circumferential internal surface to contact the second circumferential internal surface such that the collapsible conduit is a flattened cylindrical conduit. 17. The method of claim 13 wherein the conduit consists of a mesh cylinder, the conduit flattened and folded along a longitudinal dimension of the conduit such that four layers of the mesh are located such that a bottom layer contacts the container, a second layer contacts the bottom layer, a third layer contacts the second layer, and a top layer contacts the third layer. 18. The method of claim 13 further comprising locating a probe in the conduit and the probe measuring at least one characteristic of the interior of the container.