[미국특허]
Apparatus and method for beneficial modification of biorhythmic activity
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61B-005/00
A61B-005/02
A61B-005/08
A61B-005/04
출원번호
US-0323596
(2002-12-13)
등록번호
US-8672852
(2014-03-18)
발명자
/ 주소
Gavish, Benjamin
출원인 / 주소
Intercure Ltd.
대리인 / 주소
St. Onge Steward Johnston & Reens LLC
인용정보
피인용 횟수 :
6인용 특허 :
127
초록▼
Apparatus is provided, including a sensor, adapted to generate a sensor signal indicative of biorhythmic activity of a user of the apparatus, the sensor signal having a first characteristic, indicative of a voluntary action of the user, and a second characteristic, indicative of a benefit-related va
Apparatus is provided, including a sensor, adapted to generate a sensor signal indicative of biorhythmic activity of a user of the apparatus, the sensor signal having a first characteristic, indicative of a voluntary action of the user, and a second characteristic, indicative of a benefit-related variable of the user. The apparatus also includes a control unit, adapted to receive the sensor signal, and, responsive to the second characteristic, generate an output signal which directs the user to modify a parameter of the voluntary action indicated by the first characteristic.
대표청구항▼
1. Apparatus comprising: a sensor, adapted to generate a sensor signal indicative of a given biorhythmic activity of a user of the apparatus, the sensor signal having a first characteristic, indicative of a voluntary action of the user, and a second characteristic, indicative of a benefit-related va
1. Apparatus comprising: a sensor, adapted to generate a sensor signal indicative of a given biorhythmic activity of a user of the apparatus, the sensor signal having a first characteristic, indicative of a voluntary action of the user, and a second characteristic, indicative of a benefit-related variable of the user;an output unit; anda control unit, adapted to continuously: receive the sensor signal, andresponsive to the first characteristic and the second characteristic, generate an output signal which drives the output unit to direct the user to modify a parameter of the voluntary action indicated by the first characteristic,wherein the sensor is selected from the group consisting of: a sensor adapted to generate a sensor signal indicative of cardiac activity, a fast-responding temperature sensor, an electrocardiogram (ECG) monitor, at least one electromyography (EMG) electrode, a blood gas concentration sensor, a photoelectric sensor, a pulse oximeter, a photoplethysmographic sensor, a capnometer, and a laser Doppler sensor,wherein the biorhythmic activity includes respiration, and wherein the sensor is adapted to generate the sensor signal indicative of the respiration. 2. Apparatus according to claim 1, wherein the control unit is adapted to: identify an aspect of the first characteristic indicative of the user having modified the parameter to a desired extent, andresponsive to identifying the aspect of the first characteristic of the sensor signal, generate a new output signal, to direct the user to further modify the parameter of the voluntary action. 3. Apparatus according to claim 1, wherein the first characteristic is selected from the list consisting of: a period of an aspect of the sensor signal, a rate of an aspect of the sensor signal, a rise time of an aspect of the sensor signal, a fall time of an aspect of the sensor signal, a time derivative at a point of an aspect of the sensor signal, a maximum of the time derivative, a minimum of the time derivative, an amplitude of a maximum of an aspect of the sensor signal averaged over two or more biorhythmic cycles of the aspect, and an amplitude of a minimum of an aspect of the sensor signal averaged over two or more cycles of the aspect, and wherein the sensor is adapted to generate the sensor signal having the first characteristic. 4. Apparatus according to claim 1, wherein the first characteristic includes a time difference between two points of an aspect of the sensor signal, the points being part of a single cycle of the biorhythmic activity. 5. Apparatus according to claim 1, wherein the first characteristic includes a signal value difference between two points of an aspect of the sensor signal, the points being part of a single cycle of the biorhythmic activity. 6. Apparatus according to claim 1, wherein the second characteristic includes a variability of an aspect of the biorhythmic activity, the aspect selected from the list consisting of: an envelope of the biorhythmic activity, an amplitude of the biorhythmic activity, a period of the biorhythmic activity, a standard deviation (SD) of the envelope, an SD of the amplitude, and an SD of the period, and wherein the control unit is adapted to generate the output signal responsive to the variability of the aspect. 7. Apparatus according to claim 1, comprising a health status sensor, adapted to generate a health status signal indicative of a health status parameter of the user, which health status parameter is indicative of a state of health of the user, and wherein the control unit is adapted to receive the health status signal, and to determine whether the health status parameter passes a threshold value. 8. Apparatus according to claim 1, wherein the control unit is adapted to generate the output signal in the form of a game, and to alter parameters of the game so as to induce the user to modify the parameter of the voluntary action. 9. Apparatus according to claim 1, wherein the control unit is adapted to configure the output signal to direct the user to modify the parameter of the voluntary action so as to cause an improvement in the benefit-related variable. 10. Apparatus according to claim 9, wherein the benefit-related variable is a measure of baroreflex sensitivity of the user, and wherein the control unit is adapted to configure the output signal to direct the user to modify the parameter of the voluntary action so as to cause the improvement in the measure of baroreflex sensitivity. 11. Apparatus according to claim 9, wherein the benefit-related variable is selected from the list consisting of: a blood pressure of the user, a blood oxygenation saturation of the user, an end-tidal CO2 level of the user, a tissue oxygenation level of the user, a pulse-wave velocity of the user, variations in a skin blood volume of the user, an amplitude of a skin pulse volume of the user, an arterial compliance of the user, and a parameter of an electrocardiogram of the user, and wherein the control unit is adapted to configure the output signal to direct the user to modify the parameter of the voluntary action so as to cause the improvement in the benefit-related variable. 12. Apparatus according to claim 9, wherein the control unit is adapted to configure the output signal to direct the user to modify the parameter of the voluntary action so as to cause the improvement in the benefit-related variable, so as to treat a cardiovascular disease of the user. 13. Apparatus according to claim 9, wherein the control unit is adapted to configure the output signal to direct the user to modify the parameter of the voluntary action so as to cause the improvement in the benefit-related variable, so as to treat a pulmonary disease of the user. 14. Apparatus according to claim 9, wherein the control unit is adapted to configure the output signal to direct the user to modify the parameter of the voluntary action so as to cause the improvement in the benefit-related variable, so as to treat a condition of the user selected from the list consisting of: a neurological disease, hypertension, and hyperactivity. 15. Apparatus according to claim 1, wherein the output signal includes an intelligible stimulus, and wherein the control unit is adapted to generate the intelligible stimulus, so as to direct the user to modify the parameter of the voluntary action. 16. Apparatus according to claim 15, wherein the intelligible stimulus includes at least one stimulus selected from the list consisting of: an image, alpha-numeric text, a sound, a sound pattern, and a dynamic graphical pattern, and wherein the control unit is adapted to generate the stimulus, so as to direct the user to modify the parameter of the voluntary action. 17. Apparatus according to claim 15, wherein the control unit is configured to generate an error message indicative of incorrect use of the apparatus. 18. Apparatus according to claim 17, wherein, in generating the error message, the control unit is configured to indicate inappropriate mounting of the sensor. 19. Apparatus according to claim 17, wherein, in generating the error message, the control unit is configured to indicate non-compliance with usage guidelines of the apparatus. 20. Apparatus according to claim 17, wherein, in generating the error message, the control unit is configured to identify an act which may diminish effectiveness of the apparatus. 21. Apparatus according to claim 17, wherein, in generating the error message, the control unit is configured to suggest corrective action. 22. Apparatus according to claim 15, wherein the control unit is configured to generate an exercise guidance message. 23. Apparatus according to claim 22, wherein, in generating the exercise guidance message, the control unit is configured to generate a verbal message. 24. Apparatus according to claim 22, wherein, in generating the exercise guidance message, the control unit is configured to generate a visual message. 25. Apparatus according to claim 22, wherein, in generating the exercise guidance message, the control unit is configured to generate a message suitable for guiding an inexperienced user to modify the biorhythmic activity. 26. Apparatus according to claim 15, wherein the control unit is configured to generate a voice message. 27. Apparatus according to claim 15, wherein the control unit is configured to generate a warning message. 28. Apparatus according to claim 27, wherein the control unit is configured to generate the warning message in response to an indication of an undesired value of a physiological parameter. 29. Apparatus according to claim 27, wherein the control unit is configured to generate the warning message in response to an indication that a heart rate of the user is too fast. 30. Apparatus according to claim 15, wherein the control unit is configured to generate a summary message, indicative of compliance of the user. 31. Apparatus to claim 15, wherein the control unit is configured to generate an indication of performance data of the user. 32. Apparatus according to claim 1, wherein the sensor is adapted to generate the sensor signal having a third characteristic indicative of a health status parameter of the user, which health status parameter is indicative of a state of health of the user, and wherein the control unit is adapted to determine whether the health status parameter passes a threshold value. 33. Apparatus according to claim 32, wherein the control unit is adapted to withhold generating the output signal responsive to determining that the third characteristic passes the threshold value. 34. Apparatus according to claim 32, wherein the control unit is adapted to generate an alarm signal responsive to determining that the third characteristic passes the threshold value. 35. Apparatus according to claim 1, wherein the voluntary action includes the respiration, and wherein the control unit is adapted to generate the output signal to direct the user to modify a parameter of the respiration. 36. Apparatus according to claim 35, wherein the first characteristic includes at least one breathing parameter selected from: inspiration time and expiration time, and wherein the sensor is adapted to generate the sensor signal having the first characteristic. 37. Apparatus according to claim 35, wherein the first characteristic includes an average frequency of a skin pulse volume of the user, and wherein the sensor is adapted to generate the sensor signal having the first characteristic. 38. Apparatus according to claim 35, wherein the first characteristic includes an end-tidal CO2 level of the user, and wherein the sensor is adapted to generate the sensor signal having the first characteristic. 39. Apparatus according to claim 35, wherein the parameter of the respiration includes one or more timing parameters of the respiration, and wherein the control unit is adapted to generate the output signal to direct the user to modify the timing parameters of the respiration. 40. Apparatus according to claim 39, wherein the timing parameters include a pattern of inspiration and expiration of the user, and wherein the control unit is adapted to generate the output signal to direct the user to modify the pattern. 41. Apparatus according to claim 40, wherein the control unit is adapted to generate the output signal to direct the user to modify the pattern so as to reduce a ratio of a time period of the inspiration to a time period of the expiration. 42. Apparatus according to claim 1, wherein the sensor comprises a finger plethysmograph. 43. Apparatus according to claim 1, wherein the first characteristic includes a plurality of first characteristics indicative of the voluntary action of the user, and wherein the control unit is adapted to generate the output signal responsive to at least one relationship among the plurality of first characteristics. 44. Apparatus according to claim 1, wherein the sensor comprises the photoplethysmographic sensor. 45. Apparatus comprising: a sensor, adapted to generate a sensor signal indicative of a given biorhythmic activity of a user of the apparatus, the sensor signal having a first characteristic, indicative of a voluntary action of the user, and a second characteristic, indicative of a benefit-related variable of the user;an output unit; anda control unit, adapted to continuously: receive the sensor signal, andresponsive to the first characteristic and the second characteristic, generate an output signal which drives the output unit to direct the user to modify a parameter of the voluntary action indicated by the first characteristic,wherein the sensor is selected from the group consisting of: a sensor adapted to generate a sensor signal indicative of cardiac activity, a fast-responding temperature sensor, an electrocardiogram (ECG) monitor, at least one electromyography (EMG) electrode, a blood gas concentration sensor, a photoelectric sensor, a pulse oximeter, a photoplethysmographic sensor, a capnometer, and a laser Doppler sensor,wherein the control unit is adapted to configure the output signal to direct the user to modify the parameter of the voluntary action so as to cause an improvement in the benefit-related variable, andwherein the benefit-related variable is an amplitude of respiration of the user, and wherein the control unit is adapted to configure the output signal to direct the user to modify the parameter of the voluntary action so as to cause the improvement in the amplitude of the respiration. 46. Apparatus comprising: a sensor, adapted to generate a sensor signal indicative of a given biorhythmic activity of a user of the apparatus, the sensor signal having a first characteristic, indicative of a voluntary action of the user, and a second characteristic, indicative of a benefit-related variable of the user;an output unit;a control unit, adapted to continuously: receive the sensor signal, andresponsive to the first characteristic and the second characteristic, generate an output signal which drives the output unit to direct the user to modify a parameter of the voluntary action indicated by the first characteristic,wherein the sensor is selected from the group consisting of: a sensor adapted to generate a sensor signal indicative of cardiac activity, a fast-responding temperature sensor, an electrocardiogram (ECG) monitor, at least one electromyography (EMG) electrode, a blood gas concentration sensor, a photoelectric sensor, a pulse oximeter, a photoplethysmographic sensor, a capnometer, and a laser Doppler sensor,wherein the output unit comprises a speaker,wherein the output signal includes an intelligible stimulus, and wherein the control unit is adapted to generate the intelligible stimulus, so as to direct the user to modify the parameter of the voluntary action,wherein the intelligible stimulus includes music, andwherein the control unit is adapted to drive the speaker to generate the music, so as to direct the user to modify the parameter of the voluntary action. 47. Apparatus comprising: a sensor, adapted to generate a sensor signal indicative of a given biorhythmic activity of a user of the apparatus, the sensor signal having a first characteristic, indicative of a voluntary action of the user, and a second characteristic, indicative of a benefit-related variable of the user;an output unit; anda control unit, adapted to continuously: receive the sensor signal, andresponsive to the first characteristic and the second characteristic, generate an output signal which drives the output unit to direct the user to modify a parameter of the voluntary action indicated by the first characteristic,wherein the sensor is selected from the group consisting of: a sensor adapted to generate a sensor signal indicative of cardiac activity, a fast-responding temperature sensor, an electrocardiogram (ECG) monitor, at least one electromyography (EMG) electrode, a blood gas concentration sensor, a photoelectric sensor, a pulse oximeter, a photoplethysmographic sensor, a capnometer, and a laser Doppler sensor,wherein the first characteristic includes a plurality of first characteristics indicative of the voluntary action of the user, and wherein the control unit is adapted to generate the output signal responsive to at least one relationship among the plurality of first characteristics, andwherein the control unit is adapted to determine the relationship using an analysis technique selected from: cross-correlation analysis in a frequency domain and cross-correlation analysis in a time domain. 48. Apparatus comprising: a sensor, adapted to generate a sensor signal indicative of a given biorhythmic activity of a user of the apparatus, the sensor signal having a first characteristic, indicative of a voluntary action of the user, and a second characteristic, indicative of a benefit-related variable of the user;an output unit; anda control unit, adapted to continuously: receive the sensor signal, andresponsive to the first characteristic and the second characteristic, generate an output signal which drives the output unit to direct the user to modify a parameter of the voluntary action indicated by the first characteristic,wherein the sensor is selected from the group consisting of: a sensor adapted to generate a sensor signal indicative of cardiac activity, a fast-responding temperature sensor, an electrocardiogram (ECG) monitor, at least one electromyography (EMG) electrode, a blood gas concentration sensor, a photoelectric sensor, a pulse oximeter, a photoplethysmographic sensor, a capnometer, and a laser Doppler sensor,wherein the first characteristic includes a relationship among two or more spectral components that are defined by points in the sensor signal. 49. Apparatus comprising: a sensor, adapted to generate a sensor signal indicative of a given biorhythmic activity of a user of the apparatus, the sensor signal having a first characteristic, indicative of a voluntary action of the user, and a second characteristic, indicative of a benefit-related variable of the user;an output unit; anda control unit, adapted to continuously: receive the sensor signal, andresponsive to the first characteristic and the second characteristic, generate an output signal which drives the output unit to direct the user to modify a parameter of the voluntary action indicated by the first characteristic, wherein the sensor is selected from the group consisting of: a sensor adapted to generate a sensor signal indicative of cardiac activity, a fast-responding temperature sensor, an electrocardiogram (ECG) monitor, at least one electromyography (EMG) electrode, a blood gas concentration sensor, a photoelectric sensor, a pulse oximeter, a photoplethysmographic sensor, a capnometer, and a laser Doppler sensor, wherein the first characteristic includes at least one spectral component that is defined by points in the sensor signal. 50. Apparatus according to claim 49, wherein the spectral component is defined by a first subset of points in the sensor signal, the first subset of points being located among a second subset of points in the sensor signal different from the first subset of points, the first subset of points sharing a common property. 51. Apparatus according to claim 50, wherein the common property is selected from the list consisting of: local maxima and local minima of the sensor signal.
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