IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0662323
(2010-04-12)
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등록번호 |
US-8728000
(2014-05-20)
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우선권정보 |
DE-102 48 590 (2002-10-17) |
발명자
/ 주소 |
- Madaus, Stefan
- Meier, Jorg
- Heidmann, Dieter
- Schneider, Hartmut
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출원인 / 주소 |
|
대리인 / 주소 |
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인용정보 |
피인용 횟수 :
0 인용 특허 :
23 |
초록
▼
The invention relates to a method and device for carrying out a signal-processing viewing of a measurement signal that is correlated with the respiratory activity of an individual, for example, of a measurement signal that is correlated with the respiratory gas. The aim of the invention is to provid
The invention relates to a method and device for carrying out a signal-processing viewing of a measurement signal that is correlated with the respiratory activity of an individual, for example, of a measurement signal that is correlated with the respiratory gas. The aim of the invention is to provide solutions with which an improved electronic analysis of the signals that are representative with regard to respiratory activity can be achieved. To this end, the invention provides that viewing results are obtained within the scope of a signal-processing viewing of said measurement signal and make a differentiation between obstructive and central respiratory disorders possible. The viewing results are determined, in particular, while taking into account changes of selected breathing characteristics such as, for example, the change in the ratio of inhalation time to exhalation time.
대표청구항
▼
1. A method of detecting sleep-related breathing disorders in a pressure regulating device, the method comprising: measuring a signal indicative of respiratory activity;detecting an inspiration time and an expiration time of each breath for successive breaths from the signal indicative of respirator
1. A method of detecting sleep-related breathing disorders in a pressure regulating device, the method comprising: measuring a signal indicative of respiratory activity;detecting an inspiration time and an expiration time of each breath for successive breaths from the signal indicative of respiratory activity;determining a ratio of the inspiration time to the expiration time for each said breath; andanalyzing, using the pressure regulating device, variation in the ratio to determine whether a sleep-related breathing disorder has occurred or is occurring,wherein the inspiration time and expiration time are both durations of time. 2. The method of claim 1, wherein the variation in the ratio is further used to determine whether the breathing disorder was caused obstructively and whether the breathing disorder was caused centrally. 3. The method of claim 1, further comprising generating an evaluation signal that provides information as to whether imminent or already existing breathing disorders are (1)caused obstructively and/or (2) caused centrally, based on analysis of the change with respect to time of said ratio. 4. The method of claim 1, further comprising generating evaluation results that provide information as to whether a breathing disorder phase is imminent from a comparative evaluation of successively occurring changes in properties of a derivative. 5. The method of claim 4, wherein the derivative is a first derivative of respiratory gas flow in a region of a breathing phase change. 6. The method of claim 1, further comprising classifying a change in the duration of the inspiration time with respect to the expiration time as being indicative of an imminent obstruction in the upper respiratory tracts. 7. The method of claim 1, further comprising extracting evaluation results for an existing or imminent disturbance phase from comparative analysis of successively occurring changes in properties of derivatives of or within respiratory cycles. 8. The method of claim 7, wherein the derivatives correspond to a first derivative of respiratory gas flow in a region of a breathing phase change. 9. The method of claim 1, wherein the analyzing variation in the ratio is directed to a beginning portion of an inspiration cycle and/or to an end portion of the inspiration cycle. 10. The method of claim 1, further comprising analyzing a curve shape during the inspiration time. 11. The method of claim 10, further comprising calculating an average gradient in simple form for intervals that extend over a predetermined percentage of a time duration of a respective breathing phase. 12. The method of claim 10, further comprising variably calculating a gradient at a phase change within a window over the inspiration time. 13. The method of claim 1, further comprising performing trend analysis based on the nature and constitution of breathing drive. 14. The method of claim 13, further comprising performing the trend analysis based on one or more of the following signal evaluation results: max peak flow during the inspiration cycle,breath volume,the inspiration time, anda second derivative of a measured flow curve. 15. The method of claim 1, wherein signal-processing analysis is carried out based on analysis of a derivative taken at a beginning of the expiration cycle or at an end of the expiration cycle respectively. 16. The method of claim 15, further comprising performing calculations either: (a) in a simple form over a predetermined interval at the beginning of the expiration cycle and after the expiratory maximum flow; or(b) variably over the expiration cycle. 17. The method of claim 1, further comprising performing an evaluation procedure that includes analysis of one of: a maximum peak flow during an expiration cycle;one or more of the breath volume, the expiration time, and the second derivative; andcurvature of a measured flow curve during the expiration cycle. 18. The method of claim 17, further comprising generating, based on the evaluation procedure, an evaluation result that provides information regarding the nature and the constitution of the upper respiratory tracts. 19. The method of claim 1, further comprising analyzing a number of local maxima and minima, an amplitude of the local maxima and minima, a sequence of the magnitude of amplitudes of the local maxima and minima, and a frequency in the sequence of the local maxima and minima to determine whether the breathing disorder has occurred or is occurring. 20. The method of claim 1, further comprising performing spectral analysis and analysis in respect of amplitude of a snoring signal to determine whether the breathing disorder has occurred or is occurring. 21. The method of claim 1, further comprising performing trend analysis of evaluation results including combined analysis of at least two parameters. 22. The method of claim 1, further comprising performing trend analysis on analysis of variation in the ratios between two of the following parameters: inspiration time, expiration time, breath duration, breath frequency, breath volume during the inspiration cycle, breath volume during the expiration cycle, first differential and second differential of the respiratory flow, amplitudes of local maxima and local minima, frequency of local maxima and local minima, inflexion points, maximum inspiratory flow, and maximum expiratory flow. 23. The method of claim 1, further comprising generating evaluation results based on an evaluation procedure that provides information about at least one of the following: a nature of the upper respiratory tracts at least for differentiating between central and obstructive apneas,elastic properties of the upper respiratory tracts,a location of an obstruction,a degree of severity of a sleep apnea, anda Pcrit-value. 24. An apparatus including a processor configured to carry out the method set forth in claim 1. 25. An apparatus for supplying a respiratory gas to a patient at a pressure level that is above ambient pressure at least in phase-wise manner, comprising: a delivery device for delivering the respiratory gas,a measuring device configured to generate a signal indicative of the respiratory gas flow,a regulator configured to regulate the respiratory gas pressure to a predetermined reference pressure,a pressure presetting device configured to preset the reference pressure, anda signal processor configured to: (a) detect inspiration time and expiration time of each breath for successive breaths,(b) determine a ratio of the inspiration time to the expiration time for each said breath, and(c) analyze variation in the ratio to determine the occurrence of sleep-related breathing disorders,wherein the inspiration time and expiration time are both durations of time. 26. The apparatus of claim 25, further comprising a respiratory gas line extending between the delivery device and a breathing mask, and a breathing mask device. 27. The apparatus of claim 25, further comprising an evaluation apparatus configured to evaluate a series of measurement data that contains information indicative of time of the breathing of a patent, wherein the signal processing device is configured to generate, based on a variation in respiratory cycle-specific reference features obtained via differentiation, evaluation results indicative of whether or to what extent the measurement series contains sequences that are to be classified as a breathing disorder of obstructive or central origin. 28. The apparatus of claim 26, further comprising an evaluation apparatus configured to evaluate a series of measurement data that contains information indicative of time of the breathing of a patent, wherein the signal processing device is configured to generate, based on a variation in respiratory cycle-specific reference features obtained via differentiation, evaluation results indicative of whether or to what extent the measurement series contains sequences that are to be classified as a breathing disorder of obstructive or central origin. 29. The apparatus as set forth in claim 27, further comprising a display configured to provide a visualization of the measurement series at least in portion-wise manner and to distinguish sequences of presumed disturbed breathing as sequences of obstructive or central origin. 30. The apparatus as set forth in claim 28, further comprising a display configured to provide a visualization of the measurement series at least in portion-wise manner and to distinguish sequences of presumed disturbed breathing as sequences of obstructive or central origin.
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