A mechanical separator for separating a fluid sample into first and second phases is disclosed. The mechanical separator includes a float, a ballast assembly longitudinally moveable with respect to the float, and a bellows structure. The bellows structure includes a first end, a second end, and a de
A mechanical separator for separating a fluid sample into first and second phases is disclosed. The mechanical separator includes a float, a ballast assembly longitudinally moveable with respect to the float, and a bellows structure. The bellows structure includes a first end, a second end, and a deformable bellows therebetween. The float is attached to a portion of the first end of the bellows structure, and the ballast is attached to a portion of the second end of the bellows structure. The attached float and bellows structure includes a releaseable interference engagement therebetween. The float has a first density, and the ballast has a second density that is greater than the first density of the float.
대표청구항▼
1. A mechanical separator comprising: a float;a ballast assembly longitudinally moveable with respect to the float; anda bellows structure comprising a first end, a second end, and a deformable bellows therebetween, wherein the float is attached to a portion of the first end of the bellows structure
1. A mechanical separator comprising: a float;a ballast assembly longitudinally moveable with respect to the float; anda bellows structure comprising a first end, a second end, and a deformable bellows therebetween, wherein the float is attached to a portion of the first end of the bellows structure, and the ballast assembly is attached to a portion of the second end of the bellows structure, the attached float and bellows structure further comprising a releasable interference engagement therebetween for maintaining the float in fixed relation with respect to the bellows structure,wherein the bellows structure defines an interior and the float is releasably retained within a portion of the interior of the bellows structure, andwherein the releasable interference engagement comprises an interior engagement portion of the bellows structure that extends into the interior and engages an interior portion of the float. 2. The mechanical separator of claim 1, wherein the float has a first density, and the ballast has a second density that is greater than the first density of the float. 3. The mechanical separator of claim 1, wherein the releasable interference engagement is adapted to release upon exceeding a centrifugation threshold. 4. The mechanical separator of claim 1, wherein the releasable interference engagement is configured to release upon the float exceeding a centrifugal force of at least 250 g. 5. The mechanical separator of claim 1, wherein the bellows structure comprises an interior flange, and at least a portion of the float is retained within the interior of the first end by the interior flange. 6. The mechanical separator of claim 5, wherein the float comprises a neck portion and the float is releasably retained within a portion of the interior of the first end by mechanical interference of the interior flange and the neck portion. 7. The mechanical separator of claim 1, wherein the first end comprises a pierceable head portion having a puncture profile structured to resist deformation upon application of a puncture tip therethrough. 8. The mechanical separator of claim 7, wherein the float comprises a head portion defining an opening and comprising a perimeter substantially corresponding to a portion of the puncture profile of the pierceable head portion. 9. The mechanical separator of claim 1, wherein the float comprises a head portion defining an opening therethrough to allow the venting of air from within an interior of the float to an area exterior of the mechanical separator. 10. The mechanical separator of claim 1, wherein the bellows structure comprises a venting slit to allow the venting of air from within an interior of the float to an area exterior of the mechanical separator. 11. The mechanical separator of claim 1, wherein the bellows structure comprises a venting slit to allow the venting of air from a chamber defined by an interior of the bellows structure and an exterior of the float to an area exterior of the mechanical separator. 12. The mechanical separator of claim 1, wherein the ballast assembly comprises a plurality of ballast sections. 13. The mechanical separator of claim 12, wherein the ballast assembly comprises a first ballast section and a second ballast section joined to the first ballast section through a portion of the bellows structure. 14. The mechanical separator of claim 13, wherein the first ballast section and the second ballast section are opposingly oriented about a longitudinal axis of the mechanical separator. 15. The mechanical separator of claim 1, wherein the float comprises polypropylene, the ballast assembly comprises polyethylene terephthalate, and the bellows structure comprises thermoplastic elastomer. 16. The mechanical separator of claim 1, further comprising a moveable plug moveably disposed within an interior of the float. 17. A mechanical separator comprising: a bellows structure comprising a first end, a second end, and a deformable bellows therebetween;a float; and a ballast assembly longitudinally moveable with respect to the float, the ballast assembly comprising a first ballast section and a second ballast section joined to the first ballast section through a portion of the bellows structure. 18. The mechanical separator of claim 17, wherein the float has a first density, and the ballast assembly has a second density that is greater than the first density of the float. 19. The mechanical separator of claim 17, wherein the float is attached to a portion of the first end of the bellows structure, and the ballast is attached to a portion of the second end of the bellows structure, the attached float and bellows structure further comprising a releasable interference engagement therebetween for maintaining the float in fixed relation with respect to the bellows structure. 20. The mechanical separator of claim 19, wherein the releasable interference engagement is adapted to release upon centrifugation. 21. The mechanical separator of claim 17, wherein the bellows structure defines an interior and the float is releasably retained within a portion of the interior of the bellows structure. 22. The mechanical separator of claim 17, wherein the first ballast section and the second ballast section are opposingly oriented about a longitudinal axis of the mechanical separator. 23. The mechanical separator of claim 17, wherein the float comprises a head portion defining an opening therethrough to allow the venting of air from within an interior of the float to an area exterior of the mechanical separator. 24. The mechanical separator of claim 17, wherein the bellows structure comprises a venting slit to allow the venting of air from within an interior of the float to an area exterior of the mechanical separator. 25. The mechanical separator of claim 17, wherein the bellows structure comprises a venting slit to allow the venting of air from a chamber defined by an interior of the bellows structure and an exterior of the float to an area exterior of the mechanical separator. 26. A separation assembly for enabling separation of a fluid sample into first and second phases, comprising: a tube, having at least one open end, a second end, and a sidewall extending therebetween;a closure adapted for sealing engagement with the open end of the tube, the closure defining a recess; anda mechanical separator releasably engaged within the recess, the mechanical separator comprising: a float;a ballast assembly longitudinally moveable with respect to the float; anda bellows structure comprising a first end, a second end, and a deformable bellows therebetween, wherein the float is attached to a portion of the first end by releasable interference engagement therebetween for maintaining the float in fixed relation with respect to the bellows structure, and the ballast assembly is attached to a portion of the second end,wherein the releasable interference engagement comprises an interior engagement portion that extends into the interior and engages an interior portion of the float. 27. The separation assembly of claim 26, wherein the float has a first density, and the ballast assembly has a second density that is greater than the first density of the float. 28. The separation assembly of claim 26, wherein the bellows structure defines an interior and the float is releasably retained within a portion of the interior of the bellows structure. 29. The separation assembly of claim 26, wherein the releasable interference engagement is adapted to release upon centrifugation. 30. The separation assembly of claim 26, wherein the releasable interference engagement is configured to release upon the float exceeding a centrifugal force of at least 250 g. 31. The separation assembly of claim 26, wherein release of the float from the first end of the bellows structure releases the mechanical separator from the recess of the closure. 32. The separation assembly of claim 26, wherein the ballast assembly comprises a first ballast section and a second ballast section joined to the first ballast section through a portion of the bellows structure. 33. The separation assembly of claim 32, wherein the first ballast section and the second ballast section are opposingly oriented about a longitudinal axis of the mechanical separator. 34. The separation assembly of claim 26, wherein the float comprises a head portion defining an opening therethrough to allow the venting of air from within an interior of the float to an area exterior of the mechanical separator. 35. The separation assembly of claim 26, wherein the bellows structure comprises a venting slit to allow the venting of air from within an interior of the float to an area exterior of the mechanical separator. 36. The separation assembly of claim 26, wherein the bellows structure comprises a venting slit to allow the venting of air from a chamber defined by an interior of the bellows structure and an exterior of the float to an area exterior of the mechanical separator. 37. The separation assembly of claim 26, further comprising a moveable plug disposed within an interior of the float.
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