IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0045663
(2011-03-11)
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등록번호 |
US-8808258
(2014-08-19)
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발명자
/ 주소 |
- Manwaring, Michael
- Wilkes, Robert Peyton
- Leung, Braden K.
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출원인 / 주소 |
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인용정보 |
피인용 횟수 :
0 인용 특허 :
90 |
초록
▼
Methods, dressings, and systems for promoting epithelialization of a wound or other tissue are presented. The methods, dressings, and systems help form simulated rete pegs. In one instance, an epithelialization dressing is disclosed that may include a dressing body having a plurality of projections.
Methods, dressings, and systems for promoting epithelialization of a wound or other tissue are presented. The methods, dressings, and systems help form simulated rete pegs. In one instance, an epithelialization dressing is disclosed that may include a dressing body having a plurality of projections. A plurality of apertures is formed on a portion of the dressing body. The dressing helps manage fluids on the wound and the projections form cavities into which epithelial tissue migrates to from epithelial columns that function like rete pegs. Other dressings, methods, and systems are disclosed.
대표청구항
▼
1. A method for treating a wound having granulation tissue in a wound bed, the method comprising the steps of: deploying an epithelialization dressing proximate the granulation tissue in the wound bed, wherein the epithelialization dressing comprises: a dressing body having a first side and a second
1. A method for treating a wound having granulation tissue in a wound bed, the method comprising the steps of: deploying an epithelialization dressing proximate the granulation tissue in the wound bed, wherein the epithelialization dressing comprises: a dressing body having a first side and a second, tissue-facing side, wherein the dressing body comprises a plurality of apertures, each of the apertures disposed through the first side and the second, tissue-facing side, anda plurality of projections, each projection having a proximal end and a distal end, the distal end having a plurality of pores, the proximal end coupled to the second, tissue-facing side of the dressing body between the plurality of apertures;causing a compression force on the epithelialization dressing such that the plurality of projections impinge upon the granulation tissue; andallowing sufficient time for epithelium tissue to form proximate the projections. 2. The method of claim 1, further comprising: wherein the plurality of apertures provide fluid communication between the first side of the dressing body and the second, tissue-facing side of the dressing body;causing a fluid seal over the epithelialization dressing; andproviding reduced pressure to the epithelialization dressing. 3. The method of claim 1, wherein the plurality of projections further comprise supply reservoirs formed in an interior portion of the projections. 4. The method of claim 1, wherein the plurality of projections further comprise supply reservoirs formed in an interior portion of the projections and wherein the plurality of projections and the dressing body are formed of a bioresorbable material. 5. The method of claim 1, further comprising sub-features formed on the distal end of the plurality of projections and wherein the sub-features comprise ridges. 6. The method of claim 1, wherein the projections of the plurality of projections have an aspect ratio in the range of 1/10 to 10. 7. A method of forming simulated rete pegs in a wound between granulation tissue and epithelium, the method comprising: providing an epithelialization dressing comprising: a dressing body having a first side and a second, tissue-facing side, the dressing body further comprising a plurality of apertures, each of the apertures disposed through the first side and the second, tissue-facing side, anda plurality of projections coupled to the second, tissue-facing side of the dressing body between the plurality of apertures;placing the plurality of projections proximate the granulation tissue;deploying a sealing member over the epithelialization dressing and a portion of intact epidermis;providing reduced pressure through the plurality of apertures in the epithelialization dressing to cause the plurality of projections to impinge upon the granulation tissue; andallowing sufficient time for epithelial migration around the plurality of projections whereby simulated rete pegs are formed. 8. An epithelialization dressing for forming anchor points between neo-epithelium tissue and an adjacent layer of tissue, the epithelialization dressing comprising: a dressing body having a first side and a second, tissue-facing side;a plurality of projections, each projection having a proximal end and a distal end, each distal end having a plurality of pores, each proximal end coupled to the second, tissue-facing side of the dressing body, and wherein each projection has a longitudinal length in the range of 10 to 5000 microns;a plurality of apertures disposed through the first side and the second, tissue-facing side of the dressing body, wherein the plurality of projections are positioned between the plurality of apertures; andsub-features formed on the distal end of each of the plurality of projections. 9. The epithelialization dressing of claim 8, wherein the sub-features comprise grooves formed on the distal end of the projections of the plurality of projections. 10. The epithelialization dressing of claim 8, wherein the sub-features comprise a plurality of ridges formed on the distal end of the projections of the plurality of projections. 11. The epithelialization dressing of claim 8, wherein each projection has an interior portion and an exterior portion, and wherein the pores provide fluid communication between the interior portion and the exterior portion. 12. The epithelialization dressing of claim 8, wherein the plurality of projections further comprise supply reservoirs formed in an interior portion of the projections. 13. The epithelialization dressing of claim 8, wherein the plurality of projections further comprise supply reservoirs formed in an interior portion of the projections and wherein the reservoirs contain soluble factors. 14. The epithelialization dressing of claim 8, wherein the plurality of projections further comprise supply reservoirs formed in an interior portion of the projections and wherein the plurality of projections and the dressing body are formed of a bioresorbable material. 15. The epithelialization dressing of claim 8, wherein the projections of the plurality of projections have an aspect ratio in the range of 1/10 to 10. 16. A system for promoting epithelialization of a wound, the system comprising: an epithelialization dressing, the epithelialization dressing comprising: a dressing body having a first side and a second, tissue-facing side,a plurality of projections, each projection having a proximal end and a distal end, the distal end having a plurality of pores, the proximal end coupled to the second, tissue-facing side of the dressing body, anda plurality of apertures disposed through the first side and the second, tissue facing side of the dressing body, wherein the plurality of projections are positioned between the plurality of apertures;a sealing member for forming a fluid seal over the wound and the epithelialization dressing;a reduced-pressure interface for providing reduced pressure to the epithelialization dressing; anda reduced-pressure source adapted to be fluidly coupled to the reduced-pressure interface. 17. The system for promoting epithelialization of a wound of claim 16, further comprising sub-features formed on the distal end of the projections, wherein the sub-features comprise grooves. 18. The system for promoting epithelialization of a wound of claim 16, wherein the plurality of apertures comprise a plurality of slits. 19. The system for promoting epithelialization of a wound of claim 16, wherein the plurality of projections further comprise supply reservoirs formed in an interior portion of the projections. 20. The system for promoting epithelialization of a wound of claim 16, wherein the plurality of projections further comprise supply reservoirs formed in an interior portion of the projections and wherein the plurality of projections and the dressing body are formed of a bioresorbable material. 21. The system for promoting epithelialization of a wound of claim 16, wherein the projections of the plurality of projections have an aspect ratio in the range of 1/10 to 10.
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