최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0595975 (2005-05-20) |
등록번호 | US-8828203 (2014-09-09) |
국제출원번호 | PCT/IB2005/003267 (2005-05-20) |
§371/§102 date | 20091015 (20091015) |
국제공개번호 | WO2006/011062 (2006-02-02) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 0 인용 특허 : 1755 |
Methods and apparatus are provided for manufacturing an analyte detecting device. In one embodiment, the method comprises providing a substrate, applying a plurality of layer of materials on said substrate; applying a layer containing at least one mediator; and screen printing a hydrogel on the laye
Methods and apparatus are provided for manufacturing an analyte detecting device. In one embodiment, the method comprises providing a substrate, applying a plurality of layer of materials on said substrate; applying a layer containing at least one mediator; and screen printing a hydrogel on the layer.
1. A biosensor electrode with a compound an enzyme forming at least a portion of an analyte detecing member for use on an analyte detecting device, said biosensor comprising: a cross-linkable hydrophilic polymer dispersion containing a hydrophilic monomer mixture, a low molecular weight cross-linker
1. A biosensor electrode with a compound an enzyme forming at least a portion of an analyte detecing member for use on an analyte detecting device, said biosensor comprising: a cross-linkable hydrophilic polymer dispersion containing a hydrophilic monomer mixture, a low molecular weight cross-linker and a hydrophilic high molecular weight polymer and an initiator, the biosensor including a zwitterionic-surfactant, the hydrophilic molecular weight polymer including a non-ionic co-surfactant, the co-surfactant having surface active properties that increase a mobility of a mediator, a biosensor electrode having an upper portion distal from a substrate that is wider that a lower portion coupled to the upper portion and to the substrate, at least a portion of the biosensor electrode being screen printed. 2. The biosensor electrode as described in claim 1 wherein the low molecular weight cross-linker and the high molecular weight polymer are used in combination with at least one of: a hydrophilic, (partially) vinyl functionalized high molecular weight polymer, a so-called macromer. 3. The biosensor electrode as described in claim 1 wherein said compound is configured to allow rapid wicking of the analyte solution as well as rapid swelling of the resulting hydrogel membrane to allow a fast diffusion of the analyte to the enzyme. 4. The biosensor electrode as described in claim 1 wherein the compound is configured to achieve a cross-linked hydrogel to allow the permeation of low molecular weight analytes to the enzyme. 5. The biosensor electrode as described in claim 1 wherein the compound includes at least one of, N-vinyl pyrrolidone, ethylene oxide, acrylic or methacrylic acid and salts, esters and amides thereof, vinyl alcohol and derivatives thereof and glucose and the derivatives thereof. 6. The biosensor electrode as described in claim 1 wherein the compound can be partially vinyl functionalized and entrapped in or covalently bond to a formed poly vinyl matrix by thermal- or UV-induced radical polymerization. 7. The biosensor electrode as described in claim 1 wherein the compound includes a di- or polyvinylfunctional macromolecular substance based on di- or polyhydroxy-functionized polymers selected from at least one of polyvinyl alcohol and derivatives thereof, poly ethylene glycol, polyalkylen oxide, polysaccharides or hydroxy terminated polyurethane's and a macromolecular cross-linker. 8. The biosensor electrode as described in claim 1 further comprising water-soluble vinyl monomers selected from at least one of: acrylic and methacrylic acid and salts, amides and esters thereof, N-vinyl pyrrolidone and other water-soluble vinyl monomers. 9. The biosensor electrode as described in as described in claim 1 wherein the cross linker is a low molecular weight cross-linker selected from at least one of di- or polyesters, -ethers, -amides of acrylic or methacrylic acid and other radically polymerisable vinyl compounds. 10. The biosensor electrode as described in claim 1 wherein the initiator is a thermal or photochemical initiator selected from at least one of: (functionalized) alkylphenones or redox initiators, preferably UV-cleavable initiators. 11. The biosensor electrode as described in claim 1 further comprising, at least one surfactant, which enhances the wettability of an analyte solution on a surface as well as a swelling of an hydrogel coating in contact with the analyte solution. 12. The biosensor electrode as described in claim 11 wherein the surfactants are non-ionic surfactants selected from at least one of, alkylphenol polyglycol ethers, sorbitan esters, (ethoxylated) akin dolls (partially) fluorinated nonionic surfactants, anionic surfactants, alkylsulfonates, alkylbenzenesulfonates or (partially) fluorinated surfactants, or zwitter-ionic surfactants, zwitter-ionic cholic acid derivatives or betain sulfates. 13. The biosensor electrode as described in claim 11 wherein the surfactant (mixture) increases the wettability of the polymer dispersion applied on the more hydrophobic substrate surface by means of (screen-) printing. 14. The biosensor electrode as described in claim 1 wherein the polymer includes additives enabling printability, selected from at least one of, defoamers, retarders, pigments, dyes and further rheological additives.
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