초록

The present invention provides a magnetic mesoporous nanoparticle that includes a mesoporous silicate nanoparticle and iron oxide. The present invention also provides a method of using magnetic mesoporous nanoparticles to sequester microorganisms from a media.

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1. A magnetic mesoporous nanoparticle, comprising: a mesoporous silicate nanoparticle;iron oxide; andone or more amino(C1-C20)alkyl groups with alkyl units covalently bound to the mesoporous silicate nanoparticle, wherein the C1-C20 alkyl groups are independently optionally interrupted by one or two

1. A magnetic mesoporous nanoparticle, comprising: a mesoporous silicate nanoparticle;iron oxide; andone or more amino(C1-C20)alkyl groups with alkyl units covalently bound to the mesoporous silicate nanoparticle, wherein the C1-C20 alkyl groups are independently optionally interrupted by one or two —NH— groups;wherein the magnetic mesoporous nanoparticle is magnetic and comprises a mesoporous structure. 2. The magnetic mesoporous nanoparticle of claim 1, further comprising at least one microorganism, wherein the microorganism is adsorbed to the pores or surface of the magnetic mesoporous nanoparticle. 3. The magnetic mesoporous nanoparticle of claim 2, wherein the microorganism is an algae. 4. The magnetic mesoporous nanoparticle of claim 3, wherein the algae comprises Botryococcus, Chlamydomas, Chlorella, Crypthecodinium, Cyclotella, Cylindrotheca, Dunaliella, Haematococcus, Isochrysis, Monallanthus, Monoraphidium, Nannochloris, Nannochloropsis, Neochloris, Nitzschia, Phaeodactylum, Schizochytrium, Spirulina, Stichococcus, Synechocystis, Tagetes, or Tetraselmis. 5. The magnetic mesoporous nanoparticle of claim 1, wherein the magnetic mesoporous nanoparticle has a particle size of approximately 150 nm to approximately 1200 nm. 6. The magnetic mesoporous nanoparticle of claim 1, wherein the magnetic mesoporous nanoparticle has a surface area of approximately 100 m2/g to approximately 1000 m2/g. 7. The magnetic mesoporous nanoparticle of claim 1, wherein the magnetic mesoporous nanoparticle has a pore size of approximately 5 nm to approximately 15 nm. 8. The magnetic mesoporous nanoparticle of claim 1, wherein the iron oxide is Fe3O4. 9. The magnetic mesoporous nanoparticle of claim 1, wherein the iron oxide is Fe2O3. 10. A method of using magnetic mesoporous nanoparticles to sequester a microorganism from a media, comprising: contacting a mixture comprising one or more microorganisms and a media with one or more magnetic mesoporous nanoparticles each comprising a mesoporous silicate nanoparticle, Fe3O4, and one or more amino(C1-C20)alkyl groups with alkyl units covalently bound to the mesoporous silicate nanoparticle, wherein the C1-C20 alkyl groups are independently optionally interrupted by one or two —NH— groups, thereby adsorbing the microorganisms to the pores or surface of the magnetic mesoporous nanoparticles; andexposing the magnetic mesoporous nanoparticles to a magnetic field, sufficient to concentrate the adsorbed microorganisms. 11. The method of claim 10, wherein the contacting causes flocculation of the microorganisms, the magnetic mesoporous nanoparticles, or a combination thereof. 12. The method of claim 10, where one type of microorganism is selectively adsorbed over another type of microorganism. 13. The method of claim 10, wherein the magnetic mesoporous nanoparticle has a particle size of approximately 300 nm to about 600 nm. 14. The method of claim 10, further comprising separating the magnetic mesoporous nanoparticles with the adsorbed microorganisms from the media. 15. The method of claim 14, wherein at least approximately 50% of the microorganisms adsorbed and separated survive. 16. The method of claim 10, further comprising desorbing the adsorbed microorganisms from the magnetic mesoporous nanoparticles with the adsorbed microorganisms. 17. The method of claim 16, further comprising separating the desorbed microorganisms from the magnetic mesoporous nanoparticles. 18. The method of claim 17, further comprising reusing the separated magnetic mesoporous nanoparticles to adsorb microorganisms to the pores or surface of the nanoparticles. 19. The method of claim 10, wherein the microorganism is an algae.