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최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0273966 (2011-10-14) |
등록번호 | US-8889187 (2014-11-18) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 0 인용 특허 : 304 |
An antibiotic product is comprised of at least two dosages forms, each of which has a different release profile, with the Cmax for the antibiotic product being reached in less than about twelve hours. In one embodiment, there is an immediate release dosage form, as well as one or more delayed releas
An antibiotic product is comprised of at least two dosages forms, each of which has a different release profile, with the Cmax for the antibiotic product being reached in less than about twelve hours. In one embodiment, there is an immediate release dosage form, as well as one or more delayed release dosage forms, with each of the dosage forms having a different release profile, wherein each reaches a Cmax at different times.
1. A once-a-day amoxicillin product comprising at least two dosage forms, wherein the at least two dosage forms consist of a first amoxicillin dosage form and a second amoxicillin dosage form, wherein each of the first and second amoxicillin dosage forms comprises a pellet or a particle comprising a
1. A once-a-day amoxicillin product comprising at least two dosage forms, wherein the at least two dosage forms consist of a first amoxicillin dosage form and a second amoxicillin dosage form, wherein each of the first and second amoxicillin dosage forms comprises a pellet or a particle comprising a pharmaceutically active ingredient and a pharmaceutically acceptable carrier, the pharmaceutically active ingredient consisting of amoxicillin, wherein the first amoxicillin dosage form is an immediate release dosage form, the second dosage form is a delayed release dosage form, wherein the pellet or the particle of the second dosage form is coated with a non-pH sensitive delayed release component or an enteric release component, and wherein each of the first and second amoxicillin dosage farms initiates release of amoxicillin at different times and Cmax of the total amoxicillin released from the amoxicillin product is achieved in less than about 12 hours from administration, the once-a-day amoxicillin product contains the total dosage of amoxicillin for a twenty-four hour period. 2. The product of claim 1, wherein the Cmax for the product is reached no earlier than four hours after administration. 3. The product of claim 1, wherein the amoxicillin released from the first dosage form reaches a Cmax within from about 0.5 hours to about hours after administration of the product. 4. The product of claim 1, wherein the amoxicillin released from the second dosage form reaches a Cmax in no more than about 4 hours after administration of the product. 5. The product of claim 1, wherein the product is an oral dosage form. 6. The product of claim 1, wherein the pellet or the particle is formed into a unitary pharmaceutical product. 7. A process for treating a bacterial infection in a host comprising: administering to a host the amoxicillin product of claim 1 once-a-day. 8. A once-a-day amoxicillin product comprising at least two dosage forms, wherein the at least two dosage forms consist of a first amoxicillin dosage form and a second amoxicillin dosage form, wherein each of the first and second amoxicillin dosage forms comprises a pellet or a granule comprising a pharmaceutically active ingredient and a pharmaceutically acceptable carrier, the pharmaceutically active ingredient consisting of amoxicillin, wherein the first amoxicillin dosage form is an immediate release dosage form, the second dosage form is a delayed release dosage form, wherein the pellet or the granule of the second dosage form is coated with a non-pH sensitive delayed release component or an enteric release component, and wherein each of the first and second amoxicillin dosage forms initiates release of amoxicillin at different times and Cmax of the total amoxicillin released from the amoxicillin product is achieved in less than about 12 hours from administration, the once-a-day amoxicillin product contains the total dosage of amoxicillin for a twenty-four hour period. 9. The product of claim 8, wherein the Cmax for the product is reached no earlier than four hours after administration. 10. The product of claim 8, wherein the amoxicillin released from the first dosage form reaches a Cmax within from about 0.5 hours to about 2 hours after administration of the product. 11. The product of claim 8, wherein the amoxicillin released from the second dosage form reaches a Cmax in no more than about 4 hours after administration of the product. 12. The product of claim 8, wherein the product is an oral dosage form. 13. The product of claim 8, wherein the pellet or the granule is formed into a unitary pharmaceutical product.
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