The present invention provides a device and a method for application of topical antiseptics. The device comprises a handle; a base coupled to the handle; and a substantially hydrophilic foam coupled to the base. The substantially hydrophilic foam is configured to receive the topical antiseptic.
대표청구항▼
1. An applicator system, comprising: (a) an applicator device for applying a topical antiseptic to a subject's skin, said device comprising: a handle comprising a proximate end and a distal end;a base coupled to the proximate end of the handle;a substantially hydrophilic foam coupled to the base;an
1. An applicator system, comprising: (a) an applicator device for applying a topical antiseptic to a subject's skin, said device comprising: a handle comprising a proximate end and a distal end;a base coupled to the proximate end of the handle;a substantially hydrophilic foam coupled to the base;an endpiece coupled to the distal end of the handle;the topical antiseptic; andat least one abrasion layer coupled to the substantially hydrophilic foam, wherein the at least one abrasion layer is configured to abrade the subject's skin; and(b) a storage device comprising a wall and a bottom surface that defines a chamber therebetween, wherein the endpiece of the applicator device is configured to engage with the wall of the storage device to form a seal that substantially prevents contaminants from entering the chamber when the applicator device is inserted into the chamber. 2. The applicator system of claim 1, wherein the topical antiseptic is retained in the substantially hydrophilic foam. 3. The applicator system of claim 1, wherein the applicator device and the storage device are sterilized. 4. The applicator system of claim 3, wherein the topical antiseptic is sterile. 5. The applicator system of claim 1, wherein the topical antiseptic includes at least one active ingredient chosen from ethanol, isopropyl alcohol, other alcohols, and combinations thereof; benzalkonium chloride; benzethonium chloride; chlorhexidine gluconate; chloroxylenol; cloflucarban; flourosalan; hexachlorophene; hexylresorcinols; iodine containing compounds; biguanide derivatives (or a salt thereof); povidone iodine; povidone iodine with ethanol, isopropyl alcohol, other alcohols, and combinations thereof. 6. The applicator system of claim 5, wherein the at least one active ingredient is a biguanide derivative or a salt thereof. 7. The applicator system of claim 6 wherein the biguanide derivative or salt thereof is olanexidine [1-(3,4-dichlorobenzyl)-5-octylbiguanide] or a salt thereof. 8. The applicator system of claim 6, further comprising a polyoxyethylene-based nonionic surfactant. 9. The applicator system of claim 8, wherein the nonionic surfactant is at least one surfactant selected from Poloxamer 124, POE (9) lauryl ether, and POE (10) lauryl ether. 10. The applicator system of claim 8, wherein the biguanide derivative or a salt thereof is present at a concentration of about 0.05 to about 5.0% (w/v of biguanide base) and the polyoxyethyltene-based nonionic surfactant is present at a concentration of about 0.05 to about 16% (w/v). 11. The applicator system of claim 1, wherein the at least one abrasion layer comprises a textured and/or woven material. 12. The applicator system of claim 11, wherein the at least one abrasion layer includes a gauze material, which comprises cotton, rayon, nylon, or combinations thereof. 13. The applicator system of claim 1, wherein the at least one abrasion layer includes a plurality of abrasion layers in which at least one of the plurality of abrasion layers is coupled to the substantially hydrophilic foam. 14. The applicator system of claim 1, wherein the base of the applicator device is removable. 15. The applicator system of claim 1, wherein the handle of the applicator device is extendable, 16. The applicator system of claim 1, wherein the handle is configured to extend in a telescopic manner. 17. The applicator system of claim 1, wherein the handle of the applicator device is configured to extend and retract in a telescopic manner. 18. The applicator system of claim 1, wherein at least a portion of the handle of the applicator device includes a surface coating. 19. The applicator system of claim 1, wherein at least a portion of a surface of the handle of the applicator device includes a texture. 20. The applicator system of claim 1, wherein the handle of the applicator device comprises at least one indentation. 21. The applicator system of claim 1, wherein the handle of the applicator device comprises at least one protrusion. 22. The applicator system of claim 1, wherein the handle of the applicator device comprises at least one hollow region. 23. The applicator system of claim 22, wherein the handle of the applicator device comprises at least one substantially sealable membrane configured to provide access to the hollow region of the handle and through which topical antiseptic may be introduced or withdrawn. 24. The applicator system of claim 22, wherein the hollow region is configured to receive the topical antiseptic by at least one of the following: directly and indirectly. 25. The applicator system of claim 1, wherein the handle and the base of the applicator device define an angle. 26. The applicator system of claim 25, wherein the angle is about 45 degrees. 27. The applicator system of claim 25, wherein the angle is adjustable. 28. The applicator system of claim 1, wherein the storage device comprises a seat that forms a well for holding the topical antiseptic. 29. The applicator system of claim 1, wherein the applicator system is provided in ready to use form. 30. The applicator system of claim 1, wherein the handle is solid. 31. The applicator system of claim 1, wherein at least a portion of the wall of the storage device is transparent or translucent. 32. The applicator system of claim 1, wherein at least a portion of the wall of the storage device is opaque. 33. The applicator system of claim 1, wherein a cross-sectional shape of the storage device is one of circular, oval, rectangular, triangular, or polygonal. 34. An applicator system for a topical antiseptic, comprising: (a) an applicator device for applying the topical antiseptic to skin, the device including: a handle;a base coupled to one end of the handle;a substantially hydrophilic foam coupled to the base;an endpiece coupled to the handle; and(b) a storage device including: a wall and a bottom surface that defines a chamber therebetween, wherein the endpiece of the applicator device is configured to engage with the wall of the storage device to form a seal that substantially prevents contaminants from entering the chamber when the applicator device is inserted into the chamber. 35. The applicator system of claim 34, further including the topical antiseptic retained in the substantially hydrophilic foam.
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