Devices, systems and methods for medicament delivery
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-037/00
A61M-005/20
A61M-005/19
G06F-019/00
A61M-005/32
A61M-039/10
A61M-005/24
출원번호
US-0326959
(2011-12-15)
등록번호
US-8920367
(2014-12-30)
발명자
/ 주소
Edwards, Eric Shawn
Edwards, Evan Thomas
Licata, Mark J.
Meyers, Paul F.
출원인 / 주소
kaleo, Inc.
대리인 / 주소
Cooley LLP
인용정보
피인용 횟수 :
9인용 특허 :
268
초록▼
An apparatus includes a medicament container assembly, a movable assembly, and a spring. The medicament container assembly includes a first plunger defining a first volume, and a second plunger defining a second volume. The movable assembly includes a first movable member and a second movable member
An apparatus includes a medicament container assembly, a movable assembly, and a spring. The medicament container assembly includes a first plunger defining a first volume, and a second plunger defining a second volume. The movable assembly includes a first movable member and a second movable member. The second movable member can move the second plunger within the medicament container assembly. The first movable member can move the first plunger in a first direction within the medicament container assembly to expel a contents of at least the first volume via a needle. The spring is configured to urge the needle in a second direction. The release portion of the first movable member is configured to contact the second movable member after the first movable member moves the first plunger to enable the spring to move the needle in the second direction.
대표청구항▼
1. An apparatus, comprising: a medicament container assembly coupled to a needle, the medicament container assembly including a first plunger and a second plunger, the first plunger defining, at least in part, a first volume containing a first substance, the second plunger defining, at least in part
1. An apparatus, comprising: a medicament container assembly coupled to a needle, the medicament container assembly including a first plunger and a second plunger, the first plunger defining, at least in part, a first volume containing a first substance, the second plunger defining, at least in part, a second volume containing a second substance;a movable assembly including a first movable member and a second movable member, the second movable member configured to move relative to the first movable member to change the movable assembly from a first configuration to a second configuration, a distal end portion of the second movable member configured to move the second plunger within the medicament container assembly when the movable assembly is changed from the first configuration to the second configuration, the first movable member configured to move the first plunger within the medicament container assembly to expel at least at least a portion of the first substance and the second substance via the needle; anda retraction mechanism configured to retract the needle, a release portion of the first movable member configured to contact the second movable member after the first movable member moves the first plunger to enable the retraction mechanism to retract the needle. 2. The apparatus of claim 1, wherein at least one of the first substance or the second substance includes a substantially dry glucagon. 3. The apparatus of claim 1, wherein a portion of the second movable member is slidably disposed within the first movable member. 4. The apparatus of claim 1, wherein: the release portion of the first movable member is a flexible portion configured to be deformed by the second movable member to enable the retraction mechanism. 5. The apparatus of claim 1 , wherein: the first movable member is operatively coupled to a first spring configured to urge the first movable member to move the first plunger; andthe second movable member is operatively coupled to a second spring configured to produce a force to move the second movable member relative to the first movable member. 6. The apparatus of claim 1, further comprising: an actuator assembly configured to initiate a movement of the first movable member, the actuator assembly including a release member, a longitudinal axis of the release member being offset from a longitudinal axis of the medicament container assembly. 7. The apparatus of claim 1, further comprising: an actuator assembly configured to initiate movement of the second movable member, the actuator assembly including a release member configured to rotate. 8. The apparatus of claim 1, further comprising: a spring configured to exert a force on the second movable member to move the second movable member relative to the first movable member when the spring is released; andan actuation member configured to be rotated to release the spring. 9. The apparatus of claim 1, wherein: the first movable member is configured to move the first plunger in a first direction; andthe retraction mechanism includes a spring configured to retract the needle in a second direction, the second direction opposite the first direction. 10. The apparatus of claim 1, wherein the medicament container assembly is configured such that the first substance is mixed with the second substance when the movable assembly is changed from the first configuration to the second configuration. 11. An apparatus, comprising: a medicament container assembly coupled to a needle, the medicament container assembly including a first plunger and a second plunger, the first plunger defining, at least in part, a first volume, the second plunger defining, at least in part, a second volume; anda movable assembly including a first movable member and a second movable member, the second movable member configured to move relative to the first movable member to move the second plunger within the medicament container assembly, the first movable member including a release portion configured to move between a first configuration and a second configuration, the first movable member configured to move the first plunger in a first direction within the medicament container assembly to expel at least a portion of a contents of the first volume and the second volume via the needle; anda spring configured to move the needle in a second direction opposite the first direction when the spring moves from a compressed configuration to an expanded configuration, the release portion of the first movable member configured to limit movement of the spring from the compressed configuration to the expanded configuration when the release portion is in its first configuration, the release portion of the first movable member configured to be moved from its first configuration to its second configuration by a portion of the second movable member. 12. The apparatus of claim 11, wherein the first movable member is configured to be actuated independently from the second movable member. 13. The apparatus of claim 11, further comprising: a first energy storage member configured to produce a first force to move the first movable member; anda second energy storage member configured to produce a second force to move the second movable member, the second energy storage member different than the first energy storage member. 14. The apparatus of claim 11, wherein a portion of the second movable member is slidably disposed within the first movable member. 15. The apparatus of claim 11, further comprising: a spring configured to produce a force to move the second movable member relative to the first movable member; anda release member configured to release the spring when the release member is rotated. 16. The apparatus of claim 11, wherein the release portion of the first movable member is configured to be moved from its first configuration to its second configuration after the first movable member moves the first plunger. 17. The apparatus of claim 11, wherein the release portion of the first movable member enables the spring to move from the compressed configuration to the expanded configuration when contacted by the portion of the second movable member. 18. The apparatus of claim 11, wherein the release portion of the first movable member is configured to deform when moved from its first configuration to its second configuration. 19. The apparatus of claim 11, wherein the release portion of the first movable member is a flexible portion. 20. The apparatus of claim 11, wherein: the first volume contains a first substance;the second volume contains a second substance; andthe medicament container assembly is configured such that the first substance is mixed with the second substance when the second movable member is moved relative to the first movable member. 21. An apparatus, comprising: a medicament container assembly coupled to a needle, the medicament container assembly including a first plunger and a second plunger, the first plunger defining, at least in part, a first volume, the second plunger defining, at least in part, a second volume; anda movable assembly including a first movable member and a second movable member, the second movable member configured to move relative to the first movable member to move the second plunger within the medicament container assembly, the medicament container assembly configured such that the second volume is placed in fluid communication with the first volume when the second plunger is moved within the medicament container assembly, the first movable member configured to move the first plunger in a first direction within the medicament container assembly to expel at least a portion of a contents of the first volume and the second volume via the needle;a first spring configured to produce a force to move the second movable member relative to the first movable member; anda second spring configured to move the needle in a second direction opposite the first direction when the second spring moves from a compressed configuration to an expanded configuration, the first movable member including a release member configured to contact the second movable member to enable the second spring to move from the compressed configuration to the expanded configuration. 22. The apparatus of claim 21 further comprising: an actuator configured to release the first spring when the actuator is rotated. 23. The apparatus of claim 21, wherein the first movable member is configured to be actuated independently from the second movable member. 24. The apparatus of claim 21, wherein the release member of the first movable member is configured to deform when in contact with the second movable member. 25. The apparatus of claim 21, wherein: the first volume contains a first substance;the second volume contains a second substance; andthe medicament container assembly is configured such that the first substance is mixed with the second substance when the second movable member is moved relative to the first movable member.
Say James ; Tomasco Michael F. ; Heller Adam ; Gal Yoram,ILX ; Aria Behrad ; Heller Ephraim ; Plante Phillip John ; Vreeke Mark S. ; Friedman Keith A. ; Colman Fredric C., Analyte monitoring device and methods of use.
Schluter Eberhardt (Elfenbeinweg 13 Hamburg 65 DEX) Scheller Albert (Gaggenau DEX) Sprenger Rolf (Gaggenau/Winkel DEX), Automatic injection device, including an ampoule or a cartridge for an injection device.
Wilmot John G. ; Goldberg Jeffrey L. ; Page Jon ; Ketcham Cliff ; Castleberry Jeffrey P. ; Morton Jason ; Edsall Dave ; Boyd Robert R. ; Hill Robert L., Automatic injector.
Sarnoff Stanley J. (Bethesda MD) Tarello William R. (Bethesda MD) Lopez Claudio (Silver Spring MD) Karcher Daniel M. (Great Falls VA), Automatic medicament ingredient mixing and injecting apparatus.
Sarnoff Stanley J. (Bethesda MD) Tarello William R. (Bethesda MD) Lopez Claudio (Silver Spring MD) Karcher Daniel W. (Great Falls VA), Automatic medicament ingredient mixing and injecting apparatus.
Wanderer Alan A. (1075 E. Radcliffe Englewood CO 80110) Sagstetter William E. (2217 Grove Denver CO 80210), Combination needle shield/needle guard device for a hypodermic syringe with a permanently attached needle.
Edwards, Eric Shawn; Edwards, Evan Thomas; Licata, Mark J.; Meyers, Paul F.; Weinzierl, David A., Devices, systems and methods for medicament delivery.
Kaufhold ; Jr. Harry (9711 Ebb St. Houston TX 77089) Jasso Martin (Houston TX) Kruckeberg Gerald E. (Cypress TX), Disposable syringe with automatic needle retraction.
Kaufhold ; Jr. Harry (9711 Ebb St. Houston TX 77089) Jasso Martin (Houston TX) Kruckeberg Gerald E. (Cypress TX), Disposable syringe with automatic needle retraction.
Gasaway Jack S. (Irvine CA) Parsons J. Stuart (Laguna Niguel CA) Harshman Robert L. (Chino Hills CA), Gas-pressure-regulated needleless injection system.
Gravel Marian ; Gasparello Benjamin ; Ferraro Joseph ; Sharma Ashutosh ; Strowe Robert John ; Bendek Antonio A. ; Uschold Robert C. ; Antoshkiw William Thomas, Integrated system including medication delivery pen, blood monitoring device, and lancer.
Mishelevich David J. (Cupertino CA) Lanpher Ted W. (Atherton CA) Lanpher Gregory B. (York CA) Long James (Sunnyvale CA), Intelligent inhaler providing feedback to both patient and medical professional.
Simonsen, Jan Henning; Poulsen, Jens Ulrik; Rokkjaer, Kent Halfdan; Christensen, Lars Hofmann; Aasmul, S.o slashed.ren; Iav, Steffen, Medical system and a method of controlling the system for use by a patient for medical self treatment.
Edwards, Eric S.; Edwards, Evan T.; Licata, Mark J.; Meyers, Paul F.; Weinzierl, David A., Medicament delivery device configured to produce an audible output.
Pawelka Gerhard E. F. (Lexington MA) Stringer Christopher J. (San Francisco CA) Marsh Matthew (San Francisco CA) Karshmer David L. (San Francisco CA) Lada Christopher O. (Palo Alto CA) Schoenberg Ste, Multi-cartridge medication injection device.
Haber Terry M. (Lake Forest CA) Smedley William H. (Lake Elsinore CA) Foster Clark B. (Laguna Niguel CA), Multiple pharmaceutical dispenser with accumulator.
McKinnon ; Jr. Charles N. (Laguna Niguel CA) Peterson Steven F. (West Linn OR) Smith Paul E. (Tualatin OR) Nakagawa Takaaki (Tigard OR) Bartholomew Victor L. (Tigard OR), Needleless hypodermic injection device.
Peterson Steven F. (West Linn OR) McKinnon ; Jr. Charles N. (Laguna Niguel CA) Smith Paul E. (Tualatin OR) Nakagawa Takaaki (Tigard OR) Bartholomew Victor L. (Tigard OR), Needleless hypodermic injection methods and device.
Haber Terry M. (Lake Forest CA) Smedley William H. (Lake Elsinore CA) Foster Clark B. (Laguna Niguel CA), Pharmaceutical component-mixing delivery assembly.
Claeys Ronald W. (1462 “I”St. Springfield OR 97477) Decamp Gary S. (2595 Elysium Eugene OR 97401), System for verifying and recording drug administration to a patient.
Neel, Gary T.; Bell, Douglas E.; Wong, T. Philip; Voss, Houston F.; Caban, Allan Javier; Boehm, David K., Systems and methods for blood glucose sensing.
Mann, Alfred E.; Purvis, Richard E.; Mastrototaro, John J.; Causey, James D.; Henke, James; Hong, Peter; Livingston, John H.; Hague, Clifford W.; Hite, Brad T., Telemetered characteristic monitor system and method of using the same.
Smedley William H. (33285 Blanche Dr. Lake Elsinore CA 92330) Foster Clark B. (23631 Wakefield Ct. Laguna Niguel CA 92677) Haber Terry M. (25011 Castlewood Lake Forest CA 92630) ..RT: 628271 19901214, Variable proportion dispenser.
Brant Arthur ; Mandell Kenneth ; Rader R. Scott ; Walsh Alexander ; deJuan ; Jr. Eugene ; Greenberg Robert, Voice command and control medical care system.
Edwards, Eric S.; Edwards, Evan T.; Licata, Mark J.; Meyers, Paul F.; Blondino, Frank E., Devices and methods for delivering medicaments from a multi-chamber container.
Edwards, Eric S.; Edwards, Evan T.; Licata, Mark J.; Meyers, Paul F.; Blondino, Frank E., Devices and methods for delivering medicaments from a multi-chamber container.
Blondino, Frank E.; Edwards, Eric S.; Edwards, Evan T.; Kelley, Glen L.; Meyers, Paul F., Devices and methods for delivering opioid antagonists including formulations for naloxone.
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