이 특허에 인용된 특허 (106)

1. Zalipsky Shmuel (Edison NJ), Active carbonates of polyalkylene oxides for modification of polypeptides.

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2. Murphy Philip M. (Bethesda MD), Amino acid sequence for a functional human interleukin-8 receptor.

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3. Chuntharapai Anan ; Lee James ; Hebert Caroline ; Kim K. Jin, Antibodies to a human PF4 superfamily receptor.

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4. Randle Beverley J. (Bristol GB2), Antibodies, and methods for their use.

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5. Alvarez Vernon L. (Morrisville PA) Rodwell John D. (Yardley PA) Lee Chyi (New Brunswick NJ) Goers John W. F. (Atascadero CA) Siegel Richard C. (Yorktown Heights NY) McKearn Thomas J. (New Hope PA), Antibody-metal ion complexes.

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6. Polson Alan M. (Fort Collins CO) Swanbom Deryl D. (Fort Collins CO) Dunn Richard L. (Fort Collins CO) Cox Charles P. (Fort Collins CO) Norton Richard L. (Fort Collins CO) Lowe Bryan K. (Fort Collins , Biodegradable implant precursor.

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7. Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David D. (Birmingham AL), Biodegradable in-situ forming implants and methods for producing the same.

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8. Dunn Richard L. (451 Boardwalk Dr. RLD ; Apt. 501 Fort Collins CO 80526) English James P. (2500 Melinda Cir. Birmingham AL 35214) Cowsar Donald R. (4657 Round Forest Dr. Birmingham AL 35213) Vanderbi, Biodegradable in-situ forming implants and methods of producing the same.

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9. Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David D. (Birmingham AL), Biodegradable in-situ forming implants and methods of producing the same.

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10. Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David P. (Birmingham AL), Biodegradable in-situ forming implants and methods of producing the same.

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11. Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Southard George L. (Fort Collins CO) Rogers Jack A. (Fort Collins CO), Biodegradable polymer composition.

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12. Wong Johnson T. (Westwood MA) Colvin Robert B. (Cambridge MA), Bispecific antibodies for selective immune regulation and for selective immune cell binding.

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13. Allison James Patrick ; Leach Dana R. ; Krummel Matthew F., Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling.

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14. Capon Daniel J. (San Mateo CA) Gregory Timothy J. (Hillsborough CA), CD4 adheson variants.

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15. Capecchi Mario R. (Salt Lake City UT) Thomas Kirk R. (Salt Lake City UT), Cells and non-human organisms containing predetermined genomic modifications and positive-negative selection methods and.

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16. Howard Maureen ; Deshpande Shrikant ; Ferlin Walter,FRX ; Arimilli Subhashini, Chemokine receptor peptide for inducing an immune response.

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17. Capon Daniel J. (Hillsborough CA) Weiss Arthur (Mill Valley CA) Irving Brian A. (San Francisco CA) Roberts Margo R. (San Francisco CA) Zsebo Krisztina (Woodside CA), Chimeric chains for receptor-associated signal transduction pathways.

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18. Landolfi Nicholas F. (Mountain View CA), Chimeric ligand/immunoglobulin molecules and their uses.

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19. Beutler Bruce A. (Dallas TX) Peppel Karsten (Dallas TX) Crawford David F. (Irving TX), DNA encoding a chimeric polypeptide comprising the extracellular domain of TNF receptor fused to IgG, vectors, and host.

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20. Weinshank Richard L. ; Hartig Paul R., DNA encoding a human dopamine D.sub.1 receptor and uses thereof.

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21. Weinshank Richard L. ; Branchek Theresa ; Hartig Paul R., DNA encoding human 5-HT.sub.1D receptors and uses thereof.

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22. Weinshank Richard L. (New York NY) Branchek Theresa (Teaneck NJ) Hartig Paul R. (Mahwah NJ), DNA encoding human 5-HT₁D receptors.

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23. Stemmer Willem P. C. ; Crameri Andreas, DNA mutagenesis by random fragmentation and reassembly.

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24. Hansen Hans J. (Westfield NJ) Goldenberg Milton D. (Short Hills NJ), Detection and treatment of infectious and inflammatory lesions.

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25. Ladner Robert C. (Ijamsville MD) Guterman Sonia K. (Belmont MA) Roberts Bruce L. (Milford MA) Markland William (Milford MA) Ley Arthur C. (Newton MA) Kent Rachel B. (Boxborough MA), Directed evolution of novel binding proteins.

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26. Ladner Robert C. (Ijamsville MD) Guterman Sonia K. (Belmont MA) Roberts Bruce L. (Milford MA) Markland William (Milford MA) Ley Arthur C. (Newton MA) Kent Rachel B. (Boxborough MA), Directed evolution of novel binding proteins.

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27. Stemmer Willem Peter Christiaan ; Lipshutz Robert J., End-complementary polymerase reaction.

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28. Fleer Reinhard,FRX ; Fournier Alain,FRX ; Guitton Jean-Dominique,FRX ; Jung Gerard,FRX ; Yeh Patrice,FRX, Fusion polypeptides comprising human serum albumin, nucleic acids encoding same, and recombinant expression thereof.

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29. Curtis Benson M. (Seattle WA) Park Linda S. (Seattle WA) Cosman David J. (Bainbridge Island WA), Fusion proteins comprising GM-CSF and IL-3.

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30. Murata Shiro,JPX ; Toyohara Koji,JPX ; Nishikawa Naoki,JPX ; Ikariko Masahiro,JPX ; Uehara Kazuhiko,JPX ; Inoue Hideto,JPX, Game machine having play-by-play announcement.

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31. Ladner Robert C. (Ijamsville MD) Guterman Sonia K. (Belmont MA) Kent Rachel B. (Boxborough MA) Ley Arthur C. (Newton MA), Generation and selection of novel DNA-binding proteins and polypeptides.

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32. Ladner Robert C. (Ijamsville MD) Guterman Sonia K. (Belmont MA) Kent Rachel B. (Wilmington MA) Ley Arthur C. (Newton MA), Generation and selection of novel DNA-binding proteins and polypeptides.

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33. Kucherlapati Raju ; Jakobovits Aya ; Kalpholz Sue ; Brenner Daniel G. ; Capon Daniel J., Generation of xenogeneic antibodies.

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34. Wagner Thomas E. (Athens OH) Hoppe Peter C. (Bar Harbor ME), Genetic transformation of zygotes.

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35. Shenk Thomas E. (Princeton NJ) Samulski Richard J. (Pittsburgh PA) Chang Long-Sheng (Linden NJ), Helper-free stocks of recombinant adeno-associated virus vectors.

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36. Barbas Carlos (La Jolla CA) Kang Angray (Carlsbad CA) Lerner Richard A. (La Jolla CA), Heterodimeric receptor libraries using phagemids.

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37. Kucherlapati Raju (Darien CT) Koller Beverly H. (Carrboro NC) Smithies Oliver (Chapel Hill NC), Homologous recombination for universal donor cells and chimeric mammalian hosts.

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38. Kucherlapati Raju ; Jakobovits Aya ; Brenner Daniel G. ; Capon Daniel J. ; Klapholz Sue, Human antibodies derived from immunized xenomice.

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39. Kucherlapati Raju ; Jakobovits Aya ; Klapholz Sue ; Brenner Daniel G. ; Capon Daniel J., Human antibodies derived from immunized xenomice.

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40. Queen Cary L. (Los Altos CA) Selick Harold E. (Belmont CA), Humanized immunoglobulins.

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41. Queen Cary L. (Los Altos CA) Selick Harold E. (Belmont CA), Humanized immunoglobulins.

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42. Loetscher Marcel,CHX ; Moser Bernhard,CHX ; Qin Shixin ; Mackay Charles R., IP-10/Mig receptor designated CXCR3, antibodies, nucleic acids, and methods of use therefor.

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43. David Gary S. (La Jolla CA) Greene Howard E. (Carlsbad CA), Immunometric assays using monoclonal antibodies.

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44. Morgan Jeffrey R. (Brighton MA) Mulligan Richard C. (Cambridge MA), In vivo introduction and expression of foreign genetic material in epithelial cells.

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45. Ryan, Patrick J.; Davis, Michael A.; Melchior, Donald L., Liposomes containing modified cholesterol for organ targeting.

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46. Simon Jaime (Angleton TX) Garlich Joseph R. (Lake Jackson TX) Kiefer Garry E. (Richwood TX) McMillan Kenneth (Richwood TX) Frank Richard Keith (Lake Jackson TX) Goeckeler William F. (Midland MI) Ford, Macrocyclic ligands and complexes.

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47. Wilson David A. ; Garlich Joseph R. ; Fordyce William A. ; Frank R. Keith ; Simon Jaime ; Goeckler William F. ; Cheng Roberta C. ; Kruper William J. ; McMillan Kenneth, Macrocyclic tetraazacyclododecane conjugates and their use as diagnostic and therapeutic agents.

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48. Houghten Richard A. (Solana Beach CA), Means for sequential solid phase organic synthesis and methods using the same.

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49. Wilson Richard H. (Glasgow GB6) Bebbington Christopher R. (Windsor GB2), Method for dominant selection in eucaryotic cells.

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50. Wigler Michael H. ; Sorge Joseph A., Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using.

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51. Kimae Yoichi,JPX ; Yoshimatsu Shunji,JPX ; Itoda Norio,JPX ; Matsuo Takashi,JPX ; Noda Naoki,JPX, Method for manufacturing acryloxypropysilane.

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52. Hsu Chen-Chung (Taichung TWX), Method for manufacturing electrostatic discharge devices.

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53. Huang Grace P. (Miami FL) Rhode Peter R. (Miami FL) Stinson Jeffrey R. (Davie FL) Wong Hing C. (Ft. Lauderdale FL), Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage.

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54. Loetscher Marcel,CHX ; Moser Bernhard,CHX, Method of detecting or identifying ligands, inhibitors or promoters of CXC chemokine receptor 3.

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55. Galy Anne H. M., Method of identifying biological response modifiers involved in dendritic and/or lymphoid progenitor cell proliferation.

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56. Kucherlapati Raju ; Jakobovits Aya, Method of making transgenic mice lacking endogenous heavy chains.

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57. Minshull Jeremy ; Stemmer Willem P. C., Methods and compositions for cellular and metabolic engineering.

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58. Morrison Sherie L. ; Herzenberg Leonard A. ; Oi Vernon T., Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric.

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59. Stemmer Willem P. C. ; Crameri Andreas, Methods for generating polynucleotides having desired characteristics by iterative selection and recombination.

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60. Stemmer Willem P. C. (Los Gatos CA), Methods for in vitro recombination.

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61. Johnson Kevin Stuart,GBX ; Winter Gregory Paul,GBX ; Griffiths Andrew David,GBX ; Smith Andrew John Hammond,GBX ; Waterhouse Peter Michael,AUX, Methods for producing members of specific binding pairs.

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62. McCafferty John,GBX ; Pope Anthony Richard,GBX ; Johnson Kevin Stuart,GBX ; Hoogenboom Henricus Renerus Jacobus Mattheus,GBX ; Griffiths Andrew David,GBX ; Jackson Ronald Henry,GBX ; Holliger Kaspar , Methods for producing members of specific binding pairs.

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63. Weinshank Richard L. ; Branchek Theresa ; Hartig Paul R., Methods of treating migraine and compounds useful for such methods.

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64. Maione Theodore (Wakefield MA), Modified PF4 compositions and methods of use.

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65. Royer Garfield P. (Worthington OH), Modifying enzymes with polyethylene glycol and product produced thereby.

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66. Garrard Lisa J. ; Henner Dennis J. ; Bass Steven ; Greene Ronald ; Lowman Henry B. ; Wells James A. ; Matthews David J., Monovalent phage display.

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67. Boss Michael A. (Slough GBX) Kenten John H. (High Wycombe GBX) Emtage John S. (High Wycombe GBX) Wood Clive R. (Near Fordingbridge GBX), Multichain polypeptides or proteins and processes for their production.

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68. Wallach David (Rehovot ILX) Brakebusch Cord (Braunschweig DEX), Multimers of the soluble forms of TNF receptors, their preparation and pharmaceutical compositions containing them.

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69. Martinez Anthony (Hamilton Square NJ) Greenwald Richard B. (Somerset NJ), Non-antigenic branched polymer conjugates.

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70. Davis Frank F. (19 Farmingdale Rd. East Brunswick NJ 08816) Van Es Theodorus (313 Overbrook Rd. Piscataway NJ 08854) Palczuk Nicholas C. (45 W. Franklin St. Bound Brook NJ 08805), Non-immunogenic polypeptides.

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71. Robinson Randy R. ; Liu Alvin Y. ; Horowitz Arnold H. ; Better Marc ; Wall Randolph ; Lei Shau-Ping ; Wilcox Gary L., Pectate lyase signal sequence.

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72. Murphy Randall B. (Irvington NY) Schuster David I. (Wilton CT), Polypeptide derived from a popamine receptor, and compositions and methods thereof.

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73. Huston James S. (Newton MA) Oppermann Hermann (Medway MA), Polypeptide linkers for production of biosynthetic proteins.

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74. Ballance David J.,GBX ; Goodey Andrew R.,GBX, Polypeptides.

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75. Capecchi Mario R. (Salt Lake City UT) Thomas Kirk R. (Salt Lake City UT), Positive-negative selection methods and vectors.

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76. Delgado Cristina (London GBX) Francis Gillian E. (London GBX) Fisher Derek (London GBX), Process for fractionating polyethylene glycol (PEG)-protein adducts and an adduct for PEG and granulocyte-macrophage col.

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77. Hoffmann Michael K. (New York NY), Process for making human antibody producing B-lymphocytes.

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78. Osband Michal E. (Brookline MA) Cavagnaro Joy A. (Boston MA), Process for producing human antibodies.

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79. Hori Nobuaki,JPX ; Davis Claude Geoffrey ; Zsebo Krisztina M. ; Jakobovits Aya, Production of a multimeric protein by cell fusion method.

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80. Griffiths Andrew David,GBX ; Hoogenboom Hendricus Renerus Jacobus Mattheus,GBX ; Marks James David ; McCafferty John,GBX ; Winter Gregory Paul,GBX ; Grigg Geoffrey Walter,AUX, Production of anti-self antibodies from antibody segment repertoires and displayed on phage.

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81. Hoogenboom Hendricus R. J. M. (Cambridge GBX) Baier Michael (Frankfurt DEX) Jespers Laurent S. A. T. (Tervuren BEX) Winter Gregory P. (Cambridge GBX), Production of chimeric antibodies - a combinatorial approach.

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82. Treco Douglas A. (Arlington MA) Heartlein Michael W. (Boxborough MA) Selden Richard F. (Wellesley MA), Protein production and protein delivery.

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83. Reading Christopher L. (Kingwood TX), Quadroma cells and trioma cells and methods for the production of same.

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84. Thurston Marlin O. (Columbus OH) Olson Karl W. (Worthington OH), Radiation responsive surgical instrument.

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85. Lonberg Nils (San Francisco CA) Kay Robert M. (San Francisco CA), Ransgenic non-human animals for producing heterologous antibodies.

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86. Winter Gregory P. (Cambridge GBX), Recombinant altered antibodies and methods of making altered antibodies.

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87. Cabilly Shmuel (Monrovia CA) Heyneker Herbert L. (Burlingame CA) Holmes William E. (Pacifica CA) Riggs Arthur D. (La Verne CA) Wetzel Ronald B. (San Francisco CA), Recombinant immunoglobin preparations.

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88. Dower William J. (Menlo Park CA) Cwirla Steven E. (Palo Alto CA), Recombinant library screening methods.

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89. Dower William J. (Menlo Park CA) Cwirla Steven E. (Palo Alto CA), Recombinant library screening methods.

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90. Reading Christopher L. (Kingwood TX), Recombinant monoclonal antibodies.

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91. Ladner Robert C. (Ijamsville MD) Bird Robert E. (Rockville MD) Hardman Karl (Chevy Chase MD), Single polypeptide chain binding molecules.

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92. Huse William D. (Del Mar CA), Surface expression libraries of heteromeric receptors.

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93. Regen Steven L. (Milwaukee WI), Synthetic phosphatidyl cholines useful in forming liposomes.

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94. Fell ; Jr. Henry P. (Redmond WA) Gayle Margit A. (Woodinville WA), Therapeutic interleukin-2-antibody based fusion proteins.

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95. Willner David (Hamden CT) Trail Pamela A. (Farmington CT) King H. Dalton (Hamden CT) Hofstead Sandra J. (Middletown CT) Greenfield Robert S. (Wallingford CT) Braslawsky Gary R. (Glastonbury CT), Thioether conjugates.

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96. Mulligan Richard C. (Cambridge MA) Wilson James M. (Waltham MA), Transduced fibroblasts.

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97. Lonberg Nils (San Francisco CA) Kay Robert M. (San Francisco CA), Transgenic non-human animals capable of producing heterologous antibodies.

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98. Lonberg Nils (San Francisco CA) Kay Robert M. (San Francisco CA), Transgenic non-human animals capable of producing heterologous antibodies of various isotypes.

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99. Lonberg Nils (San Francisco CA) Kay Robert M. (San Francisco CA), Transgenic non-human animals capable of producing heterologous antibodies of various isotypes.

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100. Lonberg Nils (Redwood City CA) Kay Robert M. (San Francisco CA), Transgenic non-human animals for producing heterologous antibodies.

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101. Lonberg Nils ; Kay Robert M., Transgenic non-human animals for producing heterologous antibodies.

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102. Leder Philip (Chestnut Hill MA) Stewart Timothy A. (San Francisco CA), Transgenic non-human mammals.

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103. Paunescu Calin (5030 N. Marine Dr. ; Apt. 2610 Chicago IL 60640) Paunescu Tamara (Iancu Nicolaie 50 Bucharest ROX), Treatment of acne.

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104. Leder Philip (Chestnut Hill MA) Luster Andrew (Wellesley MA), Use of the cytokine IP-10 as an anti-tumor agent.

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105. Robinson Randy R. (Walnut Creek CA) Better Marc (Los Angeles CA) Lei Shau-Ping (Los Angeles CA) Wilcox Gary L. (Mill Creek WA), Vectors with pectate lyase signal sequence.

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106. Ladner, Robert C.; Guterman, Sonia K.; Roberts, Bruce L.; Markland, William; Ley, Arthur C.; Kent, Rachel B., Viruses expressing chimeric binding proteins.

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