Vinylic mask with peel-off effect for topical use containing high concentrations of retinoic acid
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61K-008/02
A01N-037/00
A61K-008/67
A61K-008/37
A61K-008/81
A61Q-019/02
A61Q-019/08
출원번호
US-0635980
(2011-09-09)
등록번호
US-8945594
(2015-02-03)
우선권정보
IT-RM2010A0473 (2010-09-10)
국제출원번호
PCT/IB2011/053947
(2011-09-09)
§371/§102 date
20120919
(20120919)
국제공개번호
WO2012/032493
(2012-03-15)
발명자
/ 주소
Crimi, Rocco
Cozzi, Raniero
출원인 / 주소
Laboratori Farmaceutici Krymi S.p.A.
대리인 / 주소
Nixon & Vanderhye PC
인용정보
피인용 횟수 :
0인용 특허 :
4
초록▼
A formulation for topical use having a filmogenic (peel-off) action for professional and home use, containing high concentrations of Retinoic acid, the method of production and use thereof in the treatment of acne, wrinkles, hyperpigmentations, psoriasis and all imperfections linked to keratinizatio
A formulation for topical use having a filmogenic (peel-off) action for professional and home use, containing high concentrations of Retinoic acid, the method of production and use thereof in the treatment of acne, wrinkles, hyperpigmentations, psoriasis and all imperfections linked to keratinization disorders. The composition also comprises octyldodecyl octyldodecanoate, and polyvinyl alcohol. The composition is in the form of a face mask (pack).
대표청구항▼
1. A composition comprising retinoic acid and polyvinyl alcohol, characterized in that it contains 1-8% by weight of retinoic acid and 8-15% by weight of octyldodecyl octyldodecanoate with reference to the total weight of the composition. 2. The composition according to claim 1, wherein the octyldod
1. A composition comprising retinoic acid and polyvinyl alcohol, characterized in that it contains 1-8% by weight of retinoic acid and 8-15% by weight of octyldodecyl octyldodecanoate with reference to the total weight of the composition. 2. The composition according to claim 1, wherein the octyldodecyl octyldodecanoate is present in a weight ratio comprised between 4:1 and 8:1 with respect to the concentration by weight of the retinoic acid. 3. The composition according to claim 1, wherein the polyvinyl alcohol is contained in a ratio comprised between 5 and 15% by weight with reference to the total weight of the composition. 4. The composition according to claim 1, further comprising denatured ethyl alcohol in a ratio of between 10 and 30% by weight with reference to the total weight of the composition. 5. The composition according to claim 1, further comprising additives selected from the group consisting of disodium EDTA, imidazolidinyl urea, acrylates/C10-30 alkyl acrylate crosspolymer, propylene glycol, and salicylic acid. 6. The composition according to claim 1, in the form of a mask. 7. A method of using the composition according to claim 1, comprising applying the composition to skin in cosmetic treatment of acne, wrinkles, hyperpigmentations, psoriasis or keratinization disorders. 8. A method of production of a composition comprising: a. combining in a vessel polyvinyl alcohol, disodium EDTA, acrylates/C10-30 alkyl acrylate crosspolymer, and propylene glycol in production water at a temperature comprised between 60 and 80° C.;b. preheating, in a separate vessel, 8-15% by weight of octyldodecyl octyldodecanoate with reference to the total weight of the composition to 40° C., to which 1-8% by weight of retinoic or 13-cis retinoic acid with reference to the total weight of the composition is added and homogenized with a turbine having a controlled speed;c. adding the mixture of step b) to the vessel of step a) with stirring;d. adding to the mixture of step c) salicylic acid pre-solubilized in denatured ethyl alcohol and imidazolidinyl urea pre-dissolved in deionized water; ande. constant stirring of the mixture of step d) until reaching a viscosity comprised between 15,000 and 23,000 mpa. 9. The composition according to claim 1, wherein the composition has (i) viscosity comprised between 15,000 and 23,000 mpa and (ii) pH comprised between 3 and 5. 10. A composition comprising 1-8% by weight of retinoic acid, 8-15% by weight of octyldodecyl octyldodecanoate, 5-15% by weight of polyvinyl alcohol, and 10-30% by weight of denatured ethyl alcohol with reference to the total weight of the composition. 11. The composition according to claim 10, wherein the octyldodecyl octyldodecanoate is present in a weight ratio comprised between 4:1 and 8:1 with respect to the concentration by weight of the retinoic acid. 12. The composition according to claim 10, wherein the composition has (i) viscosity comprised between 15,000 and 23,000 mpa and (ii) pH comprised between 3 and 5. 13. A method of using the composition according to claim 10, comprising applying the composition to skin in cosmetic treatment of acne, wrinkles, hyperpigmentations, psoriasis or keratinization disorders.
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이 특허에 인용된 특허 (4)
Herstein Morris (P.O. Box 209 Scarsdale NY 10583), Cosmetic skin-renewal-stimulating composition with long-term irritation control.
Calello Joseph Frank ; Opel Janet Elizabeth ; Ordino Renee Joan ; Sandewicz Robert Walter ; Jose Natividad R., Moisturizing cosmetic stick compositions.
Bara Isabelle (Paris FRX) Mellul Myriam (L\Hay Les Roses FRX), New cosmetic or dermopharmaceutical compositions in the form of aqueous gels modified by the addition of expanded micros.
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