초록 ▼

Various systems, methods and materials are disclosed that enable efficient delivery of an agent into an adhesively adhered article, in which the agent elicits a desired outcome, on demand. This strategy, though general in scope, is also more specifically described with regard to enabling painless or

Various systems, methods and materials are disclosed that enable efficient delivery of an agent into an adhesively adhered article, in which the agent elicits a desired outcome, on demand. This strategy, though general in scope, is also more specifically described with regard to enabling painless or atraumatic removal of products adhering to mammalian tissues such as skin and hair by suitably exploiting the ingress of an appropriate agent or like fluid. Other techniques and articles that aid in the handling or removal of such adhesive products are also disclosed.

대표청구항 ▼

1. A multilayer laminate that is adherable to a substrate and selectively releasable therefrom upon application of an agent to an outer face or perimeter of the laminate and appropriate contacting between the agent and the adhesive, the laminate comprising: an interior layer defining a plurality of

1. A multilayer laminate that is adherable to a substrate and selectively releasable therefrom upon application of an agent to an outer face or perimeter of the laminate and appropriate contacting between the agent and the adhesive, the laminate comprising: an interior layer defining a plurality of fluid passageway conduits or apertures extending through the interior layer, the interior layer exhibiting a controllable flow profile across the thickness of the interior layer, the interior layer defining a bottom surface and an oppositely directed top surface;an adhesive layer disposed along the bottom surface of the interior layer, wherein the adhesive layer includes channels incorporated in the adhesive layer of the multilayer laminate which allow for rapid ingress of an adhesive deactivating agent;a carrier layer is disposed on the top surface of the interior layer;wherein upon contacting the adhesive layer to the substrate, the laminate is adhesively adhered thereto; upon removal of the cover layer from the laminate, the interior layer and plurality of fluid passageway conduits are exposed; and upon application of an effective amount of the agent to the top surface of the interior layer, transport of the agent to the adhesive, and passage of sufficient contact time between the agent and the adhesive, the adhesively adhered laminate can be easily removed from the substrate. 2. The multilayer laminate of claim 1 wherein the adhesive of the laminate has a tackiness that decreases after the agent is applied. 3. The multilayer laminate of claim 1, wherein the conduits defined in the interior layer have diameters that range from about 0.5 mils to about 2000 mils. 4. The multilayer laminate of claim 1, wherein the interior layer includes a plurality of apertures, perforations, slits, pores or combinations thereof that enable controlled passage of one or more agents from one face of the layer through another face of the layer. 5. The multilayer laminate of claim 1, wherein the agent is an adhesive deactivating agent and is selected from the group consisting of silicones, perfluoroalkyl derivatives, low molecular weight oils, aqueous compositions, alkyl esters, limonene derivatives, paraffin solvents, hydrocarbon solvents, alkyl ethers, aromatic esters, surfactants, and combinations thereof. 6. The multilayer laminate of claim 1, wherein the number of conduits or apertures range from about 5 to about 500 per square inch of layer. 7. The multilayer laminate of claim 1, wherein the agent includes a medicant-like anesthetic, analgesic, cooling/heating agent or combination thereof. 8. The multilayer laminate of claim 1, wherein the agent is applied via a means selected from the group consisting of a secondary carrier device, a skin barrier-like application, an individually sterile packed dispenser or spray, an impregnated gauze/foam carrier, and an encapsulated release on demand medium to measure out needed amounts. 9. The multilayer laminate of claim 1, wherein the adhesive layer includes a pressure sensitive adhesive. 10. The multilayer laminate of claim 1, wherein the agent includes a component for coating hair to eliminate hair pull induced pain during removal of the laminate. 11. The multilayer laminate of claim 1, wherein the adhesive layer comprises a pattern of adhesive. 12. The multilayer laminate of claim 1, wherein the laminate further comprises a sensor incorporated into the laminate to provide information as to the state of a wound or other affected area. 13. The multilayer laminate of claim 1, wherein the interior layer is in the form of an infraction layer. 14. The multilayer laminate of claim 1, wherein the interior layer includes a region of ink conduits for facilitating fluid flow through the interior layer. 15. A system for selectively adhering and selectively releasing a multilayer laminate to and from a substrate, the system comprising: a multilayer laminate comprising (i) an interior layer defining a plurality of fluid passageway conduits or apertures extending through the interior layer, the interior layer exhibiting a controllable flow profile across the thickness of the interior layer, the interior layer defining a bottom face and an oppositely directed top face, (ii) an adhesive layer disposed along the bottom face of the interior layer, and (iii) a cover layer disposed on the top face of the interior layer;an adhesive deactivating agent;wherein upon contacting the adhesive layer to the substrate, the laminate is adhesively adhered thereto; upon removal of the cover layer from the laminate, the interior layer and plurality of fluid passageway conduits are exposed; and upon application of an effective amount of the adhesive deactivating agent to the top face of the interior layer and passage of sufficient contact time between the adhesive deactivating agent and the adhesive, the adhesively adhered laminate can be easily removed from the substrate. 16. The system of claim 15, wherein the adhesive of the laminate has a tackiness that decreases after the adhesive deactivating agent is applied. 17. The system of claim 15, wherein the conduits defined in the interior layer have diameters that range from about 0.5 mils to about 2000 mils. 18. The system of claim 15, wherein the laminate is incorporated in a medical product selected from the group consisting of bandages, dressings, gauze, tape, wound closure covers, closure strips, and pads. 19. The system of claim 15, wherein the interior layer includes a plurality of apertures, perforations, slits, pores or combinations thereof that enable controlled passage of one or more agents from one face of the layer through another face of the layer. 20. The system of claim 15, wherein the adhesive deactivating agent is selected from the group consisting of silicones, perfluoroalkyl derivatives, low molecular weight oils, aqueous compositions, alkyl esters, limonene derivatives, paraffin solvents, hydrocarbon solvents, alkyl ethers, aromatic esters, surfactants, and combinations thereof. 21. The system of claim 15, wherein the number of conduits or apertures range from about 5 to about 500 per square inch of layer. 22. The system of claim 15, wherein the adhesive deactivating agent includes a medicant-like anesthetic, analgesic, cooling/heating agent or combination thereof. 23. The system of claim 15, wherein the adhesive deactivating agent is applied via a means selected from the group consisting of a secondary carrier device, a skin barrier-like application, an individually sterile packed dispenser or spray, an impregnated gauze/foam carrier, and an encapsulated release on demand medium to measure out needed amounts. 24. The system of claim 15, wherein the adhesive layer includes a pressure sensitive adhesive. 25. The system of claim 15, wherein the adhesive layer includes channels incorporated in the adhesive layer of the multilayer laminate which allows for rapid ingress of the adhesive deactivating agent. 26. The system of claim 15, wherein the adhesive layer comprises a pattern of adhesive. 27. The system of claim 15, wherein the multilayer laminate further comprises a sensor incorporated into the laminate to provide information as to the state of a wound or other affected area. 28. The system of claim 15, wherein the adhesive deactivating agent is in the form of a spray, wipe, sterile pad or combinations thereof. 29. The system of claim 15, wherein the interior layer is in the form of an infraction layer. 30. The system of claim 15, wherein the interior layer includes a region of ink conduits for facilitating fluid flow through the interior layer. 31. A method for selectively adhering a multilayer laminate to and from a substrate, the method comprising the steps of: providing a multilayer laminate comprising (i) an interior layer defining a plurality of fluid passageway conduits or apertures extending through the interior layer, the interior layer exhibiting a controllable flow profile across the thickness of the interior layer, the interior layer defining a bottom surface and an oppositely directed top surface; (ii) an adhesive layer disposed along the bottom surface of the interior layer; (iii) a carrier layer disposed on the top surface of the interior layer; and (iv) a release liner in contact with the adhesive layer;removing the release liner from the adhesive layer of the multilayer laminate to thereby expose the adhesive layer;applying the multilayer laminate onto the substrate;removing the carrier layer to thereby expose the interior layer;applying an effective amount of an adhesive deactivating agent onto the interior layer, whereby the agent travels through the interior layer and after sufficient contact time between the agent and the adhesive, the laminate can be easily removed from the substrate. 32. The method of claim 31, wherein the multilayer laminate also comprises (v) an outer cover layer disposed adjacent the carrier layer. 33. The method of claim 31, wherein the adhesive of the laminate has a tackiness that decreases after the adhesive deactivating agent is applied. 34. The method of claim 31, wherein the conduits defined in the interior layer of the laminate have diameters that range from about 0.5 mils to about 2000 mils. 35. The method of claim 31, wherein the interior layer of the laminate includes a plurality of apertures, perforations, slits, pores or combinations thereof that enable controlled passage of one or more agents from one face of the layer through another face of the layer. 36. The method of claim 31, wherein the adhesive deactivating agent is selected from the group consisting of silicones, perfluoroalkyl derivatives, low molecular weight oils, aqueous compositions, alkyl esters, limonene derivatives, paraffin solvents, hydrocarbon solvents, alkyl ethers, aromatic esters, surfactants, and combinations thereof. 37. The method of claim 31, wherein the number of conduits or apertures in the interior layer of the laminate range from about 5 to about 500 per square inch of layer. 38. The method of claim 31, wherein the adhesive deactivating agent includes a medicant-like anesthetic, analgesic, cooling/heating agent or combination thereof. 39. The method of claim 31, wherein the adhesive deactivating agent is applied via a means selected from the group consisting of a secondary carrier device, a skin barrier-like application, an individually sterile packed dispenser or spray, an impregnated gauze/foam carrier, and an encapsulated release on demand medium to measure out needed amounts. 40. The method of claim 31, wherein the adhesive layer includes a pressure sensitive adhesive. 41. The method of claim 31, wherein the adhesive layer includes channels incorporated in the adhesive layer of the multilayer laminate which allows for rapid ingress of the adhesive deactivating agent. 42. The method of claim 31, wherein the adhesive layer comprises a pattern of adhesive. 43. The method of claim 31, wherein the multilayer laminate further comprises a sensor incorporated into the laminate to provide information as to the state of a wound or other affected area. 44. The method of claim 31, wherein the laminate is incorporated in a medical product selected from the group consisting of bandages, dressings, gauze, tape, wound closure covers, closure strips, and pads. 45. The method of claim 31, wherein the interior layer is in the form of an infraction layer. 46. The method of claim 31, wherein the interior layer includes a region of ink conduits for facilitating fluid flow through the interior layer. 47. A method for selectively adhering a multilayer laminate to a substrate and wound bed utilizing a vacuum assisted closure therapy; the method comprising the steps of: providing a multilayer laminate comprising (i) an interior layer defining a plurality of fluid passageway conduits or apertures extending through the interior layer, the interior layer exhibiting a controllable flow profile across the thickness of the interior layer, the interior layer defining a bottom surface and an oppositely directed top surface; (ii) an adhesive layer disposed along the bottom surface of the interior layer; (iii) a carrier layer disposed on the top surface of the interior layer; and (iv) a release liner in contact with the adhesive layer;placing a piece of thick material that is sized and configured to cover the wound bed, over the wound bed;peeling off the release liner from the adhesive layer of the multilayer laminate;applying the multilayer laminate over the wound bed;forming a hole in the multilayer laminate;applying a pad adapted for vacuum connection over the hole in the multilayer laminate; andconnecting a vacuum source to the pad through the hole in the multilayer laminate. 48. The method of claim 47, wherein the multilayer laminate also comprises (v) an outer cover layer disposed adjacent the carrier layer. 49. The method of claim 47, wherein the pad includes associated tubing for connection to the vacuum source. 50. The method of claim 48, wherein the pad is in contact with the outer cover layer. 51. The method of claim 47, further comprising: selectively releasing the multilayer laminate from the substrate and wound bed. 52. The method of claim 51, wherein the selective releasing is performed by treating the multilayer laminate with an adhesive deactivating agent. 53. The method of claim 52, wherein the adhesive deactivating agent is selected from the group consisting of silicones, perfluoroalkyl derivatives, low molecular weight oils, aqueous compositions, alkyl esters, limonene derivatives, paraffin solvents, hydrocarbon solvents, alkyl ethers, aromatic esters, surfactants, and combinations thereof. 54. The method of claim 52, wherein the adhesive deactivating agent includes a medicant-like anesthetic, analgesic, cooling/heating agent or combination thereof. 55. The method of claim 52, wherein the adhesive deactivating agent is applied via a means selected from the group consisting of a secondary carrier device, a skin barrier-like application, an individually sterile packed dispenser or spray, an impregnated gauze/foam carrier, and an encapsulated release on demand medium to measure out needed amounts. 56. The method of claim 47, further comprising: selectively releasing the multilayer laminate from the substrate and the wound bed by removing the pad and the multilayer laminate. 57. The method of claim 56, wherein the selective releasing is performed by treating the multilayer laminate with an adhesive deactivating agent. 58. The method of claim 47, wherein the adhesive of the laminate has a tackiness that decreases after an adhesive deactivating agent is applied. 59. The method of claim 47, wherein the conduits defined in the interior layer of the laminate have diameters that range from about 0.5 mils to about 2000 mils. 60. The method of claim 47, wherein the interior layer of the laminate includes a plurality of apertures, perforations, slits, pores or combinations thereof that enable controlled passage of one or more agents from one face of the layer through another face of the layer. 61. The method of claim 47, wherein the number of conduits or apertures in the interior layer of the laminate range from about 5 to about 500 per square inch of layer. 62. The method of claim 47, wherein the adhesive layer includes a pressure sensitive adhesive. 63. The method of claim 47, wherein the adhesive layer includes channels incorporated in the adhesive layer of the multilayer laminate which allows for rapid ingress of the adhesive deactivating agent. 64. The method of claim 47, wherein the adhesive layer comprises a pattern of adhesive. 65. The method of claim 47, wherein the multilayer laminate further comprises a sensor incorporated into the laminate to provide information as to the state of a wound or other affected area. 66. The method of claim 47, wherein the laminate is incorporated in a medical product selected from the group consisting of bandages, dressings, gauze, tape, wound closure covers, closure strips, and pads. 67. The method of claim 47, wherein the interior layer is in the form of an infraction layer. 68. The method of claim 47, wherein the interior layer includes a region of ink conduits for facilitating fluid flow through the interior layer.