An apparatus for treating a hollow anatomical structure comprises an implant comprising a plurality of bioabsorbable fibers. The implant has a compressed state in which the implant can fit within a cylindrical tube having an inside diameter of 8 French or less. The implant is expandable from the com
An apparatus for treating a hollow anatomical structure comprises an implant comprising a plurality of bioabsorbable fibers. The implant has a compressed state in which the implant can fit within a cylindrical tube having an inside diameter of 8 French or less. The implant is expandable from the compressed state to an expanded state in which the implant has sufficient size to span the inside diameter of a cylindrical tube having an inside diameter of 12 French or greater.
대표청구항▼
1. An apparatus for treating a hollow anatomical structure, said apparatus comprising: an implant comprising a plurality of loose, non-knit, non-woven, bioabsorbable fibers arranged generally parallel to each other and extending along a longitudinal axis of said implant, each of said fibers having a
1. An apparatus for treating a hollow anatomical structure, said apparatus comprising: an implant comprising a plurality of loose, non-knit, non-woven, bioabsorbable fibers arranged generally parallel to each other and extending along a longitudinal axis of said implant, each of said fibers having a number of bends along the length of the fiber, the bends providing the fiber with a greater transverse width than a fiber without bends, the bends also providing resilience to the fiber such that in a first state the fiber has a shorter length and a greater transverse width than in a second state where the fiber has a longer length and a smaller transverse width, each fiber configured for self-expansion, independent of the other fibers of the implant, in a lateral dimension transverse to the longitudinal axis through a change in shape from the second state to the first state, where the bends along the length are more pronounced in the first state compared to the second state, each of said fibers having a denier of about 0.1 to about 10;said implant configured to have a compressed state in which said implant can fit within a cylindrical tube having an inside diameter of 8 French or less;said plurality of fibers being formed into an elongate bundle of fibers comprising at least about 500 fibers and configured to be laterally expandable, due to the aggregate, unassisted self-expandability of the individual fibers, from said second state to said first state in which said implant is configured to span and conform to the inside diameter of a hollow anatomical structure having an inside diameter of 12 French or greater;said implant configured to provide a high void content scaffold within the hollow anatomical structure and to allow blood infiltration into the voids. 2. The apparatus of claim 1, wherein said implant has sufficient size, when in said expanded state, to span and conform to the inside diameter of a hollow anatomical structure having an inside diameter of 12-60 French. 3. The apparatus of claim 2, wherein said implant can pass through a cylindrical tube having an inside diameter of 6-8 French when in said compressed state. 4. The apparatus of claim 2, wherein said implant comprises a fixation element configured to limit migration of said implant when in said hollow anatomical structure. 5. The apparatus of claim 1, wherein said implant can fit within a cylindrical tube having an inside diameter of 6-8 French when in said compressed state. 6. The apparatus of claim 1, wherein said implant comprises a fixation element configured to limit migration of said implant when in said hollow anatomical structure. 7. The apparatus of claim 1, wherein said implant is laterally expandable by a factor of at least 50% of its original cross-sectional size due to the aggregate, unassisted self-expandability of the fibers. 8. The apparatus of claim 1, wherein said fibers form a vessel wall engagement surface of said implant. 9. The apparatus of claim 8, wherein said surface comprises a radially outermost portion of said implant. 10. The apparatus of claim 1, wherein the bends along the length of each of the fibers are present in both the first state and the second state. 11. An apparatus for treating a hollow anatomical structure, said apparatus comprising: an implant comprising a plurality of loose, non-knit, non-woven, bioabsorbable fibers extending generally along a longitudinal axis of said implant, each of said fibers configured for individual radial self-expansion and having an undulating configuration such that each fiber is resilient and can expand in a dimension transverse to the longitudinal axis of the implant, but under radial compression the width of the fiber decreases and the length of the fiber increases, the length extending along the longitudinal axis, the fiber having a denier of about 0.1 to about 10;said implant configured to have a compressed state in which said implant can pass through a cylindrical tube having an inside diameter of 8 French or less;said implant configured to be radially expandable, due to the aggregate, unassisted self-expandability of the individual fibers, from said compressed state to a treatment state in which said implant has a transverse size which is sufficiently large to occupy an adult human greater saphenous vein of average size while forming a high void content scaffold;said implant further configured to extend along a longitudinal axis of said greater saphenous vein to acutely slow the flow of blood through said greater saphenous vein; andsaid individual fibers configured to self-expand by assuming an increased width and a decreased length when compression is decreased on the undulating configuration of the individual fibers. 12. The apparatus of claim 11, wherein said fibers form a vessel wall engagement surface of said implant. 13. The apparatus of claim 12, wherein said surface comprises a radially outermost portion of said implant. 14. The apparatus of claim 11, wherein the undulating configuration of the fibers is present in both the compressed state and the treatment state. 15. An apparatus for occluding a hollow anatomical structure, said apparatus comprising: an implant comprising a loosely arranged, non-knit, non-woven, scaffold of fibers, said fibers being configured to be bioabsorbable and individually self-expandable, said fibers being crimped such that they have a succession of waves along the length thereof and such that they have a greater width and a shorter length in a compressed state compared to an expanded state because of the crimp retention of the individual fibers, said scaffold formed into an elongate bundle of fibers comprising at least about 500 fibers;wherein said implant in the compressed state can fit within a cylindrical tube having an inside diameter of 8 French or less; andsaid implant being laterally expandable, due to the aggregate, unassisted self-expandability of the individual fibers, from said compressed state to said expanded state in which said implant has a transverse size which is sufficiently large to span the inside diameter of a cylindrical tube having an inside diameter of 12 French or greater while forming said scaffold, said scaffold configured to have a high void content to allow blood to flow into the voids;wherein the fibers are crimped in both the compressed state and the expanded state. 16. The apparatus of claim 15, wherein said implant comprises a fixation element configured to limit migration of said implant when in said hollow anatomical structure. 17. The apparatus of claim 15, wherein said implant is laterally expandable by a factor of at least 50% of its original cross-sectional size due to the aggregate, unassisted self-expandability of the fibers. 18. The apparatus of claim 15, wherein said implant has sufficient size, when in said expanded state, to span and conform to the inside diameter of a hollow anatomical structure having an inside diameter of 24-36 French. 19. The apparatus of claim 15, wherein said fibers form a vessel wall engagement surface of said implant. 20. The apparatus of claim 19, wherein said surface comprises a radially outermost portion of said implant.
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Mirizzi,Michael Stephan; Karabey,Halil Ibrahim; Prestezog,Anna Grace; McRae,Bob, Apparatus, material compositions, and methods for permanent occlusion of a hollow anatomical structure.
Stack Richard S. (Chapel Hill NC) Clark Howard G. (Durham NC) Walker William F. (Holcomb NY) McElhaney James H. (Durham NC), Bioabsorbable stent and method of making the same.
Dunn Richard L. (451 Boardwalk Dr. RLD ; Apt. 501 Fort Collins CO 80526) English James P. (2500 Melinda Cir. Birmingham AL 35214) Cowsar Donald R. (4657 Round Forest Dr. Birmingham AL 35213) Vanderbi, Biodegradable in-situ forming implants and methods of producing the same.
Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David D. (Birmingham AL), Biodegradable in-situ forming implants and methods of producing the same.
Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Southard George L. (Fort Collins CO) Rogers Jack A. (Fort Collins CO), Biodegradable polymer composition.
Slepian Marvin J. (Cleveland Heights OH) Schindler Anton (Durham NC), Biodegradable polymeric endoluminal sealing process, apparatus and polymeric product for use therein.
Bays F. Barry (Seminole FL) Dunn Richard L. (Birmingham AL) Marchand Sam (Olive Branch MS) Treharne ; III Richard W. (Memphis TN), Biodegradable prosthetic device.
McGurk Erin (Palo Alto CA) Dieck Ronald (Palo Alto CA) Tremulis William S. (Redwood City CA), Embolic elements and methods and apparatus for their delivery.
Conston Stanley R. (San Carlos CA) Dapper Gregory S. (Newark CA) Murphy Aileen L. (Menlo Park CA) Raeder-Devens Jennifer (Oakland CA) Yamamoto Ronald (San Francisco CA), Embolization plugs for blood vessels.
Guglielmi Guido, Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas.
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Farley, Brian E.; Henderson, Dawn A.; Jones, Christopher S.; Parker, Mark P.; Tartaglia, Joseph M., Expandable vein ligator catheter and method of use.
Hubbell Jeffrey A. (Austin TX) Pathak Chandrashekhar P. (Waltham MA) Sawhney Amarpreet S. (Newton MA) Desai Neil P. (Los Angeles CA) Hill-West Jennifer L. (Austin TX) Hossainy Syed F. A. (Austin TX), Gels for encapsulation of biological materials.
Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hill Jennifer L. ; Hossainy Syed F. A., Gels for encapsulation of biological materials.
Guglielmi Guido (Santa Monica CA) Sepetka Ivan (Redwood City CA), In an endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms,.
Rhee Woonza M. ; Berg Richard A. ; Chu George H. ; DeLustro Frank A. ; Jolivette Dan M. ; McCullough Kimberly A., Injectable or implantable biomaterials for filling or blocking lumens and voids of the body.
John M. Ronan ; Samuel A. Thompson, Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties.
Tang Reginald T. (Warren NJ) Mares Frank (Whippany NJ) Boyle ; Jr. William J. (Parsippany NJ) Chiu Tin-Ho (Millburn NJ) Patel Kundanbhai M. (Landing NJ), Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lact.
Hunter,William L.; Gravett,David M.; Toleikis,Philip M.; Maiti,Arpita; Signore,Pierre E.; Liggins,Richard T.; Guan,Dechi, Medical implants and fibrosis-inducing agents.
Laufer Michael D. (Menlo Park CA) Montgomery H. DuBose (Menlo Park CA), Method and apparatus for minimally invasive treatment of chronic venous insufficiency.
Goldman Mitchel P. ; Weiss Robert A. ; Zikorus Arthur W. ; Chandler James G., Method for applying energy to biological tissue including the use of tumescent tissue compression.
Makower, Joshua; Flaherty, J. Christopher; Machold, Timothy R.; Whitt, Jason B.; Evard, Philip C.; Macaulay, Patrick E.; Garibotto, John T.; Jensen, Marc, Methods and apparatus for blocking flow through blood vessels.
Whalen, II, Thomas J.; Tran, Chinh Ngoc; Hayman, Douglas Ray; Roth, Noah Michael; Moret, Jacques; Greff, Richard J., Methods for embolizing vascular sites with an embolizing composition.
Whalen, II, Thomas J.; Greff, Richard J.; Gilmartin, Kevin P.; Hayman, Douglas Ray; Hewitt, Todd J.; Olson, Ed L.; Pecor, Mark A.; Slee, Earl H.; Wallace, George, Methods for treating aneurysms.
Hubbell Jeffrey A. (Austin TX) Pathak Chandrashekhar P. (Waltham MA) Sawhney Amarpreet S. (Newton MA) Desai Neil P. (Los Angeles CA) Hill Jennifer L. (Austin TX), Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
Hubbell Jeffrey A. (Austin TX) Pathak Chandrashekhar P. (Waltham MA) Sawhney Amarpreet S. (Newton MA) Desai Neil P. (Los Angeles CA) Hill Jennifer L. (Austin TX), Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
Sing,Eduardo Chi; Urquidi,Luis; Ashby,Mark; Cragg,Andrew; Furey,Tom; Bowes,Robert; Tangherlini,Vincent, Pledget-handling system and method for delivering hemostasis promoting material to a blood vessel puncture site by fluid pressure.
Seedhom Bahaa B. (75 ; Holt Park Crescent Leeds ; West Yorkshire ; LS16 7SL GB2) Fujikawa Kyosuke (Department of Orthopaedic Surgery ; Keio School of Medicine Tokyo JPX), Prosthetic ligaments and instruments for use in the surgical replacement of ligaments.
Hlavacek Robert A. (New Haven CT) Dumican Barry L. (Fairfield CT) McCusker Edward J. (Fairfield CT), Surgical repair device having absorbable and nonabsorbable components.
LaFontaine,Daniel M.; Harrison,Kent D.; Euteneuer,Charles L.; Hastings,Roger N.; Wang,Lixiao, System and method for percutaneous coronary artery bypass.
Kensey Kenneth (Chester Springs PA) Nash John E. (Downington PA) Evans Douglas (Devon PA), System for closing a percutaneous puncture formed by a trocar to prevent tissue at the puncture from herniating.
Kensey Kenneth (Chester Springs PA) Nash John E. (Downington PA) Evans Douglas (Devon PA), System for closing a percutaneous puncture formed by a trocar to prevent tissue at the puncture from herniating.
McCrory, Jennifer; Luscher, Patrik; Kamath, Kalpana; Sahatjian, Ronald, System for implanting a cross-linked polysaccharide fiber and methods of forming and inserting the fiber.
Ritchart Mark (Santa Clara CA) Mariant Mike (Santa Clara CA) Sepetka Ivan (Santa Clara CA) Engelson Erik (Portola Valley CA), Vaso-occlusion coil and method.
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