Cosmetic compositions for increasing bioavailability of the active compounds baicalin and/or vitamin C
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61K-009/00
A61K-047/12
A61K-047/22
A61K-031/7048
A61K-008/368
A61K-008/49
A61K-008/67
A61Q-019/00
출원번호
US-0650933
(2012-10-12)
등록번호
US-9018177
(2015-04-28)
발명자
/ 주소
Lauten, Elizabeth Hunter
Simonnet, Jean-Thierry
Pan, Zhi
Balooch, Guive
출원인 / 주소
L'Oreal S.A.
대리인 / 주소
Novak Druce Connolly Bove + Quigg LLP
인용정보
피인용 횟수 :
0인용 특허 :
14
초록
Aqueous compositions comprising a) at least one active compound and b) at least one hydrotrope in an amount effective to increase transdermal penetration of the active compound, and methods for increasing bioavailability of active compounds are provided.
대표청구항▼
1. An aqueous cosmetic skin-care composition comprising; (a) about 0.5 wt. % of baicalin and/or about 10 wt. % vitamin C;(b) about 5 wt. % of each of the hydrotropes caffeine and niacinamide, wherein the amount of said hydrotropes is effective to increase transdermal penetration of baicalin and/or v
1. An aqueous cosmetic skin-care composition comprising; (a) about 0.5 wt. % of baicalin and/or about 10 wt. % vitamin C;(b) about 5 wt. % of each of the hydrotropes caffeine and niacinamide, wherein the amount of said hydrotropes is effective to increase transdermal penetration of baicalin and/or vitamin C; and(c) water;wherein said skin care composition is in the form of a lotion, serum, gel, milk, foam, liquid foundation, or cream, and is suitable for topical application to the skin. 2. The composition of claim 1, wherein the composition is a serum. 3. The composition of claim 2, wherein the serum further comprises dipropylene glycol, PEG-4, and/or alcohol. 4. The composition of claim 1, wherein the composition is an oil-in-water emulsion. 5. The composition of claim 4, wherein the oil-in-water emulsion further comprises: polysorbate 61, phenoxyethanol, sodium stearoyl glutamate, disodium EDTA, octocrylene, isopropyl lauroyl sarcosinate, octyldodecanol (and) oxtyldodecyl xyloside, glyceryl stearate, stearyl alcohol, caprylyl glycol, p-anisic acid, and/or isotridecyl isononanoate. 6. The composition of claim 1, further comprising: (d) at least one additive conventionally used in the cosmetics field selected from the group consisting of a thickener, a fragrance, a pearlescent agent, a preservative, a sunscreen, an anionic polymer, a nonionic polymer, a cationic polymer, an amphoteric polymer, a protein, a protein hydrolysate, a fatty acid, a vitamin, panthenol, a silicone, a vegetable oil, an animal oil, a mineral oil, a synthetic oil, a gelling agent, an antioxidant, a solvent, a filler, an odor absorber, and a coloring material. 7. A method for increasing the bioavailability of vitamin C and/or baicalin comprising topically applying to skin an aqueous cosmetic skin-care composition according to claim 1. 8. A method for protecting skin from photoaging comprising applying a composition according to claim 1 to the skin. 9. An aqueous cosmetic skin-care composition comprising; (a) about 0.5 wt. % of baicalin and about 10 wt. % vitamin C; (b) about 5 wt. % of each of the hydrotropes caffeine and niacinamide, wherein the amount of said hydrotropes is effective to increase transdermal penetration of baicalin and vitamin C;(c) water; and(d) at least one additive conventionally used in the cosmetics field selected from the group consisting of a thickener, a fragrance, a pearlescent agent, a preservative, a sunscreen, an anionic polymer, a nonionic polymer, a cationic polymer, an amphoteric polymer, a protein, a protein hydrolysate, a fatty acid, a vitamin, panthenol, a silicone, a vegetable oil, an animal oil, a mineral oil, a synthetic oil, a gelling agent, an antioxidant, a solvent, a filler, an odor absorber, and a coloring material;wherein said skin care composition is in the form of a lotion, serum, gel, milk, foam, liquid foundation or cream and is suitable for topical application to the skin. 10. The composition of claim 9, wherein the composition is a serum. 11. The composition of claim 9, wherein the composition further comprises dipropylene glycol, PEG-4, and/or alcohol. 12. The composition of claim 9 comprising 5 wt. % to 40 wt. % of component (d). 13. A method for increasing the bioavailability of vitamin C and/or baicalin comprising topically applying to skin an aqueous cosmetic skin-care composition according to claim 9. 14. A method for protecting skin from photoaging comprising applying a composition according to claim 9 to the skin.
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이 특허에 인용된 특허 (14)
Markson Stephen A., Aqueous caffeine dosage forms.
Boutique, Jean-Pol; Broeckx, Walter August Maria; Coosemans, Steven Jozef Louis; Gualco, Lorenzo Matteo Pierre; Johnston, James Pyott; Tcheou, Eric; Ingram, David William, Detergent compositions comprising hydrotropes.
Balentine Douglas A. (River Vale NJ) Harbowy Matthew E. (New Brunswick NJ), Process for preparation of purified tea components using preconcentration by cream separation and solubilization followe.
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