[특허]Quantitative, non-invasive, clinical diagnosis of traumatic brain injury using VOG device for neurologic optokinetic testing

[미국특허] Quantitative, non-invasive, clinical diagnosis of traumatic brain injury using VOG device for neurologic optokinetic testing 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61B-005/00 A61B-003/02
출원번호	US-0336254 (2014-07-21)
등록번호	US-9039632 (2015-05-26)
발명자 / 주소	Kiderman, Alexander D Schroeder, Howison Joos, Thomas Frank, Greg Sweeney, Daniel Baker, Thomas Vernon
출원인 / 주소	NEURO KINETICS, INC
대리인 / 주소	Shideler, Blynn L.
인용정보	피인용 횟수 : 3 인용 특허 : 96

초록 ▼

A portable VOG device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol including optokinetic testing that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.

대표청구항 ▼

1. A method of diagnosis of traumatic brain injury or concussion in a subject comprising the steps of: A) providing a system including a stimulus generating portion and an eye tracking portion;B) presenting visual stimulus to the subject via the stimulus generating portion, wherein the visual stimulus presented to the subject via the stimulus generating portion forms the optical target stimulus for at least one optokinetic test;C) obtaining objective physiologic response of the subject in the form of reflexive ocular-motor responses of the subject's eyes from the eye tracking portion based upon each of the visual stimulus presented to the subject in each optokinetic test; andD) using the objective physiologic responses including the reflexive ocular-motor responses of the subject's eyes to the optical target stimulus of each optokinetic test to diagnose the presence of traumatic brain injury. 2. The method of diagnosis of traumatic brain injury according to claim 1, further including the step of obtaining pre-trauma objective physiologic responses of the subject from based upon each of the visual stimulus presented to the subject for each optokinetic test, wherein the pre-trauma objective physiologic responses for each optokinetic test form a baseline for the subject. 3. The method of diagnosis of traumatic brain injury according to claim 2, wherein the step of using the objective physiologic responses to diagnose the presence of traumatic brain injury includes a determining whether at least one post-trauma objective physiologic responses of the subject differs from the associated pre-trauma objective physiologic response by greater than a preset threshold for that response. 4. The method of diagnosis of traumatic brain injury according to claim 1, wherein the step of using the objective physiologic responses to diagnose the presence of traumatic brain injury includes a determining whether at least one post-trauma objective physiologic responses of the subject for each optokinetic test differs from an associated objective physiologic response of a normative database of similar subjects for each optokinetic test by greater than a preset threshold for that response. 5. A method of diagnosis of traumatic brain injury in a subject comprising the steps of: A) providing a head mounted stimulus generating eye tracking goggle unit coupled to the subject and generating a plurality of visual stimulus for the subject;B) presenting the plurality of visual stimulus to the subject, wherein each visual stimulus is presented in the eye tracking unit, wherein each visual stimulus provides a target stimulus for a distinct visual based neurologic optokinetic test;C) obtaining objective physiologic response of the subject from the eye tracking unit in the form of reflexive ocular-motor responses of the subiect's eyes based upon each of neurologic optokinetic test associated with each visual stimulus presented to the subject; andD) using the objective physiologic responses to the neurologic optokinetic tests including the reflexive ocular-motor responses of the subiect's eyes to the optical target stimulus to diagnose the presence of traumatic brain injury. 6. The method of diagnosis of traumatic brain injury according to claim 5, wherein the step of using the objective physiologic responses to diagnose the presence of traumatic brain injury includes a determining whether at least one post-trauma objective physiologic responses of the subject for each optokinetic test differs from an associated objective physiologic response of a normative database of similar subjects for each optokinetic test by greater than a preset threshold for that response. 7. The method of diagnosis of traumatic brain injury according to claim 5, further including the step of obtaining pre-trauma objective physiologic responses of the subject for each optokinetic test from the head mounted goggle unit based upon each of the visual stimulus presented to the subject for each optokinetic test, wherein the pre-trauma objective physiologic responses for each optokinetic test form a baseline for the subject. 8. The method of diagnosis of traumatic brain injury according to claim 7, wherein the step of using the objective physiologic responses to diagnose the presence of traumatic brain injury includes a determining whether at least one post-trauma objective physiologic responses of the subject differs from the associated pre-trauma objective physiologic response by greater than a preset threshold for that response.

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[미국특허] Quantitative, non-invasive, clinical diagnosis of traumatic brain injury using VOG device for neurologic optokinetic testing 원문보기

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[미국특허] Quantitative, non-invasive, clinical diagnosis of traumatic brain injury using VOG device for neurologic optokinetic testing 원문보기

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