Medicament comprising a peptide extract of avocado, which is intended for the treatment and prevention of illnesses that are linked to an immune system deficiency or oxidative stress or skin ageing or dry skin
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61K-036/00
A61K-036/54
A61K-031/198
출원번호
US-0539970
(2009-08-12)
등록번호
US-9089576
(2015-07-28)
우선권정보
FR-04 04640 (2004-04-30)
발명자
/ 주소
Piccirilli, Antoine
Piccardi, Nathalie
Msika, Philippe
Paul, François
Bredif, Stéphanie
출원인 / 주소
LABORATOIRES EXPANSCIENCE
대리인 / 주소
Foley & Lardner LLP
인용정보
피인용 횟수 :
7인용 특허 :
7
초록▼
The invention relates to a medicament which comprises a peptide extract of avocado and which can also comprise a composition containing D-mannoheptulose an/or perseitol, such as a water-soluble extract of avocado sugars, and/or a peptide extract of lupine. The inventive medicament is intended for th
The invention relates to a medicament which comprises a peptide extract of avocado and which can also comprise a composition containing D-mannoheptulose an/or perseitol, such as a water-soluble extract of avocado sugars, and/or a peptide extract of lupine. The inventive medicament is intended for the treatment and/or prevention of illnesses that are linked to an alteration in innate and/or acquired immunity, through an increase in the production of anti-microbial peptides, preferably hBD-2, without inducing inflammatory reactions, irritations or intolerances.
대표청구항▼
1. A method for the protection of skins selected from the group consisting of: immature newborn infants' or children's skins;pathological immature newborn infants' or children's skins;healthy or pathological skins in adults or aged individuals;skins which have been weakened by an aggression from env
1. A method for the protection of skins selected from the group consisting of: immature newborn infants' or children's skins;pathological immature newborn infants' or children's skins;healthy or pathological skins in adults or aged individuals;skins which have been weakened by an aggression from environment; orskins with a deficiency in the skin barrier;comprising administering a drug comprising 0.1% to 20% by weight of an avocado peptide extract in relation to the total weight of the drug, wherein said avocado peptide extract is obtained by enzymatic hydrolysis, and an appropriate excipient to a patient in need thereof. 2. The method according to claim 1, wherein 50% by weight of peptides in the extract, compared to the total peptides by weight in the extract, are made up of 10-30 amino acids. 3. The method according to claim 1, wherein the drug further comprises D-mannoheptulose and/or perseitol. 4. The method according to claim 1, wherein the source of D-mannoheptulose and/or perseitol is a hydrosoluble avocado sugar extract. 5. The method according to claim 1, to protect the skin from ageing or photoageing. 6. The method according to claim 1, wherein 50% by weight of peptides in the extract, compared to the total peptides weight in the extract, are made up of less than 30 amino acids. 7. The method according to claim 1, wherein at least 50% by weight of peptides in the extract, compared to the total peptides weight in the extract, are made up of 10-30 amino acids. 8. A process for the cosmetic treatment of sensitive, irritated, allergic, dry, aged, intolerant skins and/or mucosae, with a deficiency in the skin barrier, skins and/or mucosae, which have been weakened by an aggression from the environment, skins and/or mucosae with reddenings or with an non pathological immunological imbalance, comprising applying onto the skin and/or the mucosae a composition comprising 0.1% to 20% by weight of an avocado peptide extract in relation to the total weight of the composition, wherein said avocado peptide extract is obtained by enzymatic hydrolysis, and an appropriate excipient, to a patient in need thereof. 9. The process according to claim 8, wherein the composition further comprises D-mannoheptulose and/or perseitol. 10. The process according to claim 8, wherein the source of D-mannoheptulose and/or perseitol is an avocado sugar hydrosoluble extract. 11. A process according to claim 8 for the cosmetic treatment of aged skin and/or mucosae. 12. The method according to claim 8, wherein 50% by weight of peptides in the extract, compared to the total peptides weight in the extract, are made up of less than 30 amino acids. 13. The method according to claim 8, wherein at least 50% by weight of peptides in the extract, compared to the total peptides weight in the extract, are made up of 10-30 amino acids.
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이 특허에 인용된 특허 (7)
Msika Philippe,FRX ; Rancurel Alain,FRX ; Montaudoin Marie-Georgette,FRX, Antioxidant and/or antielastase composition based on lupine oil.
Broutin, Nicole; Legrand, Jacques; Piccirilli, Antoine, Method for extracting compounds of furan lipids and polyhydroxylated fatty alcohols of avocado, composition based on said compounds, and therapeutic, cosmetical or food use of said compounds.
Boileau, Thomas William-Maxwell; Ceddia, Michael Anthony; Collins, John Kevin; Davenport, Gary Mitchell; Kiely, Barry Pius; O'Mahony, Liam Diarmuid; Sunvold, Gregory Dean; Tetrick, Mark Alan; Vickers, Robert Jason, Canine probiotic bifidobacterium pseudolongum.
Massimino, Stefan Patrick; Davenport, Gary Mitchell; Hayek, Michael Griffin; Roth, George; Ingram, Donald K., Method for decreasing inflammation and stress in a mammal.
Boileau, Thomas William-Maxwell; Ceddia, Michael Anthony; Davenport, Gary Mitchell; Kiely, Barry Pius; O'Mahony, Liam Diarmuid; Sunvold, Gregory Dean; Tetrick, Mark Alan; Vickers, Robert Jason, Methods of use of probiotic bifidobacteria for companion animals.
Kerr, George Scott; Sunvold, Gregory Dean; Schumacher, Lawrence Andrew; Schuller, David William; ter Haar, Robbert H; Bittner, Michael J, Probiotic supplement, process for making, and packaging.
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