[특허]Use of TNFα inhibitor for treatment of psoriasis

[미국특허] Use of TNFα inhibitor for treatment of psoriasis 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	C07K-016/28 A61K-039/395 C07K-016/24
출원번호	US-0681704 (2015-04-08)
등록번호	US-9090689 (2015-07-28)
발명자 / 주소	Hoffman, Rebecca S. Weinberg, Mark Banerjee, Subhashis Taylor, Lori K. Spiegler, Clive E. Tracey, Daniel E. Chartash, Elliot K. Barchuk, William T. Yan, Philip Murtaza, Anwar Salfeld, Jochen G. Fischkoff, Steven A. Granneman, George R.
출원인 / 주소	AbbVie Biotechnology Ltd.
대리인 / 주소	Foley Hoag LLP
인용정보	피인용 횟수 : 4 인용 특허 : 73

초록 ▼

The invention describes methods of treating erosive polyarthritis comprising administering a TNFα antibody, or antigen-binding portion thereof. The invention also describes a method for testing the efficacy of a TNFα antibody, or antigen-binding portion thereof, for the treatment of erosive polyarth

대표청구항 ▼

1. A method of administering adalimumab for treatment of moderate to severe chronic plaque psoriasis, comprising filling adalimumab into vessels and subcutaneously administering 40 mg of said adalimumab to a patient having moderate to severe chronic plaque psoriasis every other week. 2. The method of claim 1, wherein adalimumab in said vessels is formulated at a concentration of 50 mg/ml. 3. The method of claim 2, wherein said vessels each contains 40 mg of adalimumab. 4. The method of claim 1, wherein said vessels are syringes. 5. The method of claim 4, wherein adalimumab in said syringes is formulated at a concentration of 50 mg/ml. 6. The method of claim 5, wherein said syringes each contains 40 mg of adalimumab. 7. A method of preparing adalimumab for treating moderate to severe chronic plaque psoriasis, comprising filling adalimumab into vessels and providing said adalimumab for treatment, wherein said treatment comprises subcutaneously administering 40 mg of said adalimumab to a patient having moderate to severe chronic plaque psoriasis every other week. 8. The method of claim 7, wherein adalimumab in said vessels is formulated at a concentration of 50 mg/ml. 9. The method of claim 8, wherein said vessels each contains 40 mg of adalimumab. 10. The method of claim 7, wherein said vessels are syringes. 11. The method of claim 10, wherein adalimumab in said syringes is formulated at a concentration of 50 mg/ml. 12. The method of claim 11, wherein said syringes each contains 40 mg of adalimumab. 13. The method of claim 7, wherein at least 5% body surface area (BSA) of the patient is affected by the psoriasis. 14. The method of claim 13, wherein adalimumab in said vessels is formulated at a concentration of 50 mg/ml. 15. The method of claim 14, wherein each said vessels are syringes and each contains 40 mg of adalimumab. 16. The method of claim 7, wherein said patient has both psoriasis and psoriatic arthritis and achieves at least a 75% reduction in Psoriasis Area and Severity Index (PASI) score at week 12 of the treatment. 17. The method of claim 16, wherein adalimumab in said vessels is formulated at a concentration of 50 mg/ml. 18. The method of claim 17, wherein each said vessels are syringes and each contains 40 mg of adalimumab. 19. The method of claim 7, wherein said patient has both psoriasis and psoriatic arthritis and achieves at least a Physician Global Assessment (PGA) score of clear or almost clear at week 12 of the treatment. 20. The method of claim 19, wherein adalimumab in said vessels is formulated at a concentration of 50 mg/ml. 21. The method of claim 20, wherein each said vessels are syringes and each contains 40 mg of adalimumab.

이 특허에 인용된 특허 (73) 인용/피인용 타임라인 분석

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Tobinick, Edward L., Cytokine antagonists for the treatment of localized disorders.
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Edward L. Tobinick, Cytokine antagonists for the treatment of sensorineural hearing loss.
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Salfeld, Jochen G.; Allen, Deborah J.; Hoogenboom, Hendricus R. J. M.; Kaymakcalan, Zehra; Labkovsky, Boris; Mankovich, John A.; McGuinness, Brian T.; Roberts, Andrew J.; Sakorafas, Paul; Schoenhaut,, Human antibodies that bind human TNFa.
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Salfeld, Jochen G.; Allen, Deborah J.; Hoogenboom, Hendricus R. J. M.; Kaymakcalan, Zehra; Labkovsky, Boris; Mankovich, John A.; McGuinness, Brian T.; Roberts, Andrew J.; Sakorafas, Paul; Schoenhaut, David; Vaughan, Tristan J.; White, Michael; Wilton, Alison J., Human antibodies that bind human TNFα.
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연합인증

[미국특허] Use of TNFα inhibitor for treatment of psoriasis 원문보기

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이 특허에 인용된 특허 (73) 인용/피인용 타임라인 분석

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[미국특허] Use of TNFα inhibitor for treatment of psoriasis 원문보기

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