Systems and methods for delivering therapeutic agents
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-001/00
A61M-013/00
A61M-037/00
A61M-005/155
A61M-011/02
A61M-005/20
출원번호
US-0725206
(2012-12-21)
등록번호
US-9101744
(2015-08-11)
발명자
/ 주소
Ducharme, Richard W
출원인 / 주소
COOK MEDICAL TECHNOLOGIES LLC
대리인 / 주소
Brinks Gilson & Lione
인용정보
피인용 횟수 :
0인용 특허 :
144
초록▼
The present embodiments provide systems and methods suitable for delivering a therapeutic agent to a target site. The systems generally comprise a container having first and second regions and a reservoir containing the therapeutic agent. A pressure source having pressurized fluid is in selective fl
The present embodiments provide systems and methods suitable for delivering a therapeutic agent to a target site. The systems generally comprise a container having first and second regions and a reservoir containing the therapeutic agent. A pressure source having pressurized fluid is in selective fluid communication with at least a portion of the reservoir. An outlet tube is in fluid communication with the reservoir of the container. At least one slot is formed in a lateral surface of the outlet tube at a position between first and second ends of the outlet tube.
대표청구항▼
1. A system suitable for delivering a therapeutic agent to a target site, the system comprising: a container for holding the therapeutic agent, wherein the container comprises first and second regions and has a reservoir containing the therapeutic agent;a pressure source having pressurized fluid, th
1. A system suitable for delivering a therapeutic agent to a target site, the system comprising: a container for holding the therapeutic agent, wherein the container comprises first and second regions and has a reservoir containing the therapeutic agent;a pressure source having pressurized fluid, the pressure source in selective fluid communication with at least a portion of the reservoir of the container;an outlet tube in fluid communication with the reservoir of the container;at least one slot formed in a circumferential surface of the outlet tube at a position between first and second ends of the outlet tube; andan inlet tube disposed within the container, the inlet tube having a first end positioned near the first region of the container and a second end positioned near the second region of the container, wherein the fluid from the pressure source flows through the inlet tube in the direction from the first region to the second region and into the reservoir of the container. 2. The system of claim 1, wherein fluid from the pressure source is directed through the first region of the container in a direction towards the second region of the container, and wherein the fluid is at least partially redirected to urge the therapeutic agent in a direction from the second region of the container towards the first region of the container and subsequently towards the target site. 3. The system of claim 1, where the first end of the outlet tube is disposed closer to a target site and the second end of the outlet tube is disposed proximal to the first end, where the at least one slot is positioned closer to the first end than the second end of the outlet tube. 4. The system of claim 1 where the at least one slot extends between about 45 and about 270 degrees around a perimeter of the outlet tube. 5. The system of claim 1 wherein, during use, the first region of the container is disposed vertically above the second region of the container. 6. The system of claim 1 further comprising a cap secured to the first region of the container, the cap having an inlet port and an outlet port, wherein the fluid from the pressure source is directed through the inlet port of the cap, and wherein the fluid is redirected within the container to urge the therapeutic agent through the outlet port of the cap. 7. The system of claim 1 wherein the outlet tube is disposed at least partially within the container, wherein fluid exiting the second end of the inlet tube urges the therapeutic agent into the second end of the outlet tube and towards the first end of the outlet tube. 8. The system of claim 7 wherein the second end of the outlet tube is spaced away from the second end of the inlet tube. 9. The system of claim 1 further comprising a platform positioned within the container, the platform forming a substantially fluid tight seal with an inner surface of the container, wherein the therapeutic agent is retained above the platform. 10. The system of claim 1 wherein the therapeutic agent comprises a powder. 11. A system suitable for delivering a therapeutic agent to a target site, the system comprising: a container for holding the therapeutic agent, wherein the container comprises first and second regions and has a reservoir containing the therapeutic agent;a pressure source having pressurized fluid, the pressure source in selective fluid communication with at least a portion of the reservoir of the container;an outlet tube in fluid communication with the reservoir of the container;at least one slot formed in a circumferential surface of the outlet tube at a position between first and second ends of the outlet tube; anda platform positioned within the container, the platform forming a substantially fluid tight seal with an inner surface of the container, wherein the therapeutic agent is retained above the platform,wherein the slot is closer to the target site relative to the platform. 12. The system of claim 11, wherein fluid from the pressure source is directed through the first region of the container in a direction towards the second region of the container, and wherein the fluid is at least partially redirected to urge the therapeutic agent in a direction from the second region of the container towards the first region of the container and subsequently towards the target site. 13. The system of claim 11, where the first end of the outlet tube is disposed closer to a target site and the second end of the outlet tube is disposed proximal to the first end, where the at least one slot is positioned closer to the first end than the second end of the outlet tube. 14. The system of claim 11 where the at least one slot extends between about 45 and about 270 degrees around a perimeter of the outlet tube. 15. The system of claim 11 wherein, during use, the first region of the container is disposed vertically above the second region of the container. 16. The system of claim 11 further comprising a cap secured to the first region of the container, the cap having an inlet port and an outlet port, wherein the fluid from the pressure source is directed through the inlet port of the cap, and wherein the fluid is redirected within the container to urge the therapeutic agent through the outlet port of the cap. 17. The system of claim 11 further comprising an inlet tube disposed within the container, the inlet tube having a first end positioned near the first region of the container and a second end positioned near the second region of the container, wherein the fluid from the pressure source flows through the inlet tube in the direction from the first region to the second region and into the reservoir of the container. 18. The system of claim 17 wherein the outlet tube is disposed at least partially within the container, wherein fluid exiting the second end of the inlet tube urges the therapeutic agent into the second end of the outlet tube and towards the first end of the outlet tube. 19. The system of claim 18 wherein the second end of the outlet tube is spaced away from the second end of the inlet tube. 20. The system of claim 11 wherein the therapeutic agent comprises a powder.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (144)
Gertner, Michael E., Aerosol device to deliver bioactive agent.
Reh Lothar (Zumikon CHX) Tesch Marc (Forch CHX) Hani Beat (Zuzwil CHX) Ruf Arthur (Schwerzenbach CHX) Meili Thomas (Zurich CHX) Goedicke Frank (Niederhelfenschwil CHX), Apparatus and method for dosing.
Reh Lothar (Zumikon CHX) Tesch Marc (Forch CHX) Hni Beat (Zuzwil CHX) Ruf Arthur (Schwerzenbach CHX), Apparatus and method for dosing a particulate phase present in a gas/particle flow from a fluidized bed.
Rowe Stephen C. (Wellesley MA) Hubbell Jeffrey A. (San Marino CA) Herman Stephen J. (Andover MA) Sun Vae (Palo Alto CA) Lang Michael F. (North Andover MA) Selecman George E. (Marblehead MA) Ahari Fre, Apparatus and method for local application of polymeric material to tissue.
Linder Albert (Leonberg-Hoefingen DEX) Kellner Andreas (Ulrichskirchen ATX) Habison Georg (Vienna ATX) Zuelow Guenther (Vienna ATX), Apparatus for applying a multiple-component tissue adhesive.
Sanford John C. (Geneva NY) Wolf Edward D. (Ithaca NY) Allen Nelson K. (Newfield NY), Biolistic apparatus for delivering substances into cells and tissues in a non-lethal manner.
Hollars, Anthony Scott, Compressed gas cartridge dispensing system allowing interchangeable use of different capacity compressed gas cartridges and novel storage feature.
Widran Jerrold (60 Estate Dr. Glencoe IL 60022) Krebs Helmut (4849 N. Kenneth Chicago IL 60630), Continuous flow urological endoscopic apparatus and method of using same.
Glines, Robert C.; Weller, Gary B., Device and methods for the delivery and injection of therapeutic and diagnostic agents to a target site within a body.
Shishov Nikolai M. (Moscow SUX) Zelenetsky Vladimir E. (Moscow SUX) Demina Nadezhda A. (Moscow SUX) Bondarev Ivan M. (Moscow SUX) Cherny Alexandr N. (Moscow SUX) Moskvitin Valery A. (Belgorod-Dnestro, Device for administering powdered substances.
Melanson David A. ; Levine Marc Alan ; Spiridigliozzi John C. ; Bromander Thomas S. ; Pichon Dean M. ; Selecman George ; Nedder David J., Device for priming for improved adherence of gels to substrates.
Sandow Jrgen K. (Knigstein/Taunus DEX) De Felice Wilfried (Kelkheim DEX) Pajunk Horst (Geisingen DEX) Pajunk Heinrich (Geisingen DEX), Device for the administration of implants.
Niels Erik Holm DK; Steven Linnebjerg DK; Richard Cornwell GB, Devices and methods for applying a mixture of two or more liquid components to form a biomaterial.
Cowan, Kevin P.; Trombley, III, Frederick W.; Reilly, David M.; Griffiths, David M.; Misic, George J.; Callan, Keith, Devices, systems and methods for delivery of a fluid into a patient during a magnetic resonance procedure.
Li Lehmann K. (Fairfield CT) Warren Russell F. (Greenwich CT) Arnoczky Steven P. (New York NY) Bedard Robert J. (Southbury CT), Fibrin clot delivery device and method.
Yves Delmotte BE; Arnold Bilstad ; David Amrani ; James DiOrio ; Atif M. Yardimci ; David W. Pennington ; James S. Slepicka ; Cristina Stadler, Fibrin delivery device and method for forming fibrin on a surface.
Tilton ; Jr. Eugene B. (513 Dorrington Blvd. Metairie LA 70005), Instrumentation for laparoscopic insertion and application of sheet like surgical material.
Sanford John C. (Geneva) DeVit Michael J. (Geneva NY) Bruner Ronald F. (Sewell NJ) Johnston Stephen A. (Durham NC), Method and apparatus for introducing biological substances into living cells.
Sperry Charles R. (Springfield VT) Raff Allan M. (Walnut Creek CA), Method for the cleansing of wounds using an aerosol container having liquid wound cleansing solution.
Sanford John C. (Geneva NY) Wolf Edward D. (Ithaca NY) Allen Nelson K. (Newfield NY), Method for transporting substances into living cells and tissues and apparatus therefor.
Plouhar Pamela L. ; Dunn Michael D. ; Lower Jerry L. ; May Thomas C., Method of making reconstructive SIS structure for cartilaginous elements in situ.
Pawelka Gerhard E. F. (Lexington MA) Stringer Christopher J. (San Francisco CA) Marsh Matthew (San Francisco CA) Karshmer David L. (San Francisco CA) Lada Christopher O. (Palo Alto CA) Schoenberg Ste, Multi-cartridge medication injection device.
Christou Paul (Madison WI) McCabe Dennis (Middleton WI) Swain William F. (Madison WI) Barton Kenneth A. (Middleton WI), Particle-mediated transformation of soybean plants and lines.
Haber Terry M. (Lake Forest CA) Smedley William H. (Lake Elsinore CA) Foster Clark B. (Laguna Niguel CA), Pharmaceutical storage and mixing syringe having high pressure assisted discharge.
Kensey Kenneth (Chester Springs PA) Nash John (Downingtown PA) Evans Douglas (King of Prussia PA), Plug device with pulley for sealing punctures in tissue and methods of use.
Pingleton Edward D. ; Butler Gary L. ; Fearnot Neal E. ; Hollinger Donald R. ; Vendrely Timothy G. ; Clayman Ralph V., Pneumatic tissue dissector with exhaust system.
Barrington James E. (Woburn MA) Williams David L. (Reading MA) Hitchcock Charles J. (Cambridge MA) Mullins Thomas J. (Woburn MA), Powder blower device.
Terakura Seiji (Ikoma JPX) Maeda Toyoyuki (Kawachinagano JPX), Powdered medicament-mixed gas injecting apparatus and powdered medicament-mixed gas injecting nozzle to be connected to.
Magro Alfred E. (Woburn MA) Rishton Michael (Reading MA), Tapered hemostatic device for use in conjunction with a catheter for alleviating blood leakage and method for using same.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.