Devices and methods for sleep apnea treatment
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61N-001/36
A61F-005/56
A61B-017/24
출원번호
US-0633670
(2012-10-02)
등록번호
US-9205262
(2015-12-08)
발명자
/ 주소
Bolea, Stephen
Tesfayesus, Wondimeneh
Beck, John
Hoegh, Thomas
Atkinson, Robert
Hauschild, Sidney
출원인 / 주소
CYBERONICS, INC.
대리인 / 주소
Bookoff McAndrews
인용정보
피인용 횟수 :
6인용 특허 :
199
초록▼
Devices and methods for improving the coupling between the soft palate and the genioglossus. This may be accomplished, for example, but shortening or stiffening the palatoglossal arch. Improved coupling between the soft palate and the genioglossus may be beneficial to a patient suffering from obstru
Devices and methods for improving the coupling between the soft palate and the genioglossus. This may be accomplished, for example, but shortening or stiffening the palatoglossal arch. Improved coupling between the soft palate and the genioglossus may be beneficial to a patient suffering from obstructive sleep apnea (OSA) as a stand-alone procedure, or in combination procedures and devices that cause anterior displacement of the tongue such as hypoglossal nerve stimulation, genioglossus advancement surgery, mandibular advancement surgery, mandibular advancement (oral) appliances, etc.
대표청구항▼
1. A method of treating an upper airway tissue collapse condition of a patient, comprising: Implanting at least one tissue engagement member in the patient's upper airway tissue to improve a coupling between the patient's genioglossus muscle and a portion of the patient's upper airway tissue; andpro
1. A method of treating an upper airway tissue collapse condition of a patient, comprising: Implanting at least one tissue engagement member in the patient's upper airway tissue to improve a coupling between the patient's genioglossus muscle and a portion of the patient's upper airway tissue; andproviding a stimulation therapy that delivers an electrical stimulation to a hypoglossal nerve of the patient to cause an advancement of the patient's genioglossus muscle and/or an anterior movement of the patient's tongue, the stimulation therapy having an efficacy in the treatment of the upper airway tissue collapse condition, wherein the at least one tissue engagement member improves the efficacy of the stimulation therapy. 2. A method as in claim 1, wherein improving the coupling between the patient's genioglossus muscle and the portion of the patient's upper airway tissue includes tightening the patient's pharyngeal tissue. 3. A method as in claim 2, wherein tightening the patient's pharyngeal tissue includes shortening the patient's palatoglossus. 4. A method as in claim 2, wherein tightening the patient's pharyngeal tissue includes shortening the patient's palatopharyngeus. 5. A method as in claim 2, wherein tightening the patient's pharyngeal tissue includes shortening the patient's pharyngoepiglottic fold. 6. A method as in claim 1, wherein the stimulation therapy causes genioglossus contraction. 7. The method as in claim 1, wherein the upper airway tissue collapse condition is an obstructive sleep apnea condition of the patient, and wherein the efficacy of the stimulation therapy mitigates the obstructive sleep apnea condition. 8. The method as in claim 1, wherein the upper airway tissue collapse condition includes a first tissue collapse at a first location within the patient's upper airway and a second tissue collapse at a second location within the patient's upper airway, wherein the efficacy of the stimulation therapy corresponds to a mitigation of the first tissue collapse at the first location, and wherein the improvement of the efficacy of the stimulation therapy corresponds to a mitigation of the second tissue collapse at the second location. 9. A method of treating an upper airway tissue collapse condition of a patient, comprising: modifying a first length of the patient's palatoglossus to a shortened second length by implanting at least one tissue engagement member in a first portion of tissue disposed at the patient's palatoglossus to improve a coupling between a movement of the patient's tongue and a corresponding movement of a second portion of tissue disposed in the couplings upper airway;disposing a stimulation device configured to electrically stimulate the patient to move the patient's tongue anteriorly, the patient's tongue being coupled to the second portion of tissue via the first portion of tissue; andmaintaining the corresponding movement of the second portion of tissue when delivering an electrical stimulation. 10. A method as in claim 9, wherein disposing the stimulation device includes implanting the stimulation device, and delivering the electrical stimulation to includes electrically stimulating a nerve innervating an upper airway muscle of the patient. 11. A method as in claim 10, wherein the nerve includes a hypoglossal nerve. 12. A method as in claim 9, further comprising causing the patient's tongue to move anteriorly by performing a genioglossus advancement surgical procedure. 13. A method as in claim 9, further comprising causing the patient's tongue to move anteriorly by implanting a device in communication with the tongue. 14. A method as in claim 9, further comprising causing the patient's tongue to move anteriorly by performing a mandibular advancement surgical procedure. 15. A method as in claim 9, further comprising causing the patient's tongue to move anteriorly by using an oral appliance. 16. A method as in claim 15, wherein the oral appliance is a mandibular advancement device. 17. The method as in claim 9, wherein the upper airway tissue collapse condition is an obstructive sleep apnea condition of the patient, and wherein electrically stimulating the patient to move the patient's tongue mitigates the obstructive sleep apnea condition. 18. The method as in claim 9, wherein the upper airway tissue collapse condition includes a first tissue collapse at a first location within the patient's upper airway and a second tissue collapse at a second location within the patient's upper airway, wherein electrically stimulating the patient to move the patient's tongue corresponds to a mitigation of the first tissue collapse at the first location, and wherein the modifying of the patient's palatoglossus corresponds to a mitigation of the second tissue collapse at the second location. 19. A method as in claim 9, wherein modifying the first length of the patient's palatoglossuss to the shortened second length includes a surgical shortening of the patient's palatoglossus. 20. A method of treating an upper airway tissue collapse condition of a patient, comprising: Implanting at least one tissue engagement member in the patient's upper airway tissue to tighten the patient's upper airway from a first condition of the patient's upper airway tissue to a second condition of the patient's upper airway tissue that has a greater stiffness than the first condition. the patient's upper airway issue in the second condition conveying anterior movement of the patient's tongue to maintain a patency of the patient's upper airway; anddisposing a stimulation device configured for delivering an electrical stimulation to a nerve innervating a tongue protruder muscle of the patient to cause an anterior movement of the patient's tongue, wherein the at least one tissue engagement member improves an efficacy of the electrical stimulation. 21. A method as in claim 20, wherein tightening the patient's upper airway tissue includes tightening the patient's pharyngeal tissue. 22. A method as in claim 21, wherein tightening the patient's pharyngeal tissue includes shortening one of the patient's palatoglossus, palatopharyngeus, and pharyngoepiglottic fold. 23. The method as in claim 20, wherein the upper airway tissue collapse condition is an obstructive sleep apnea condition of the patient, and wherein the delivering of the electrical stimulation mitigates the obstructive sleep apnea condition. 24. The method as in claim 20, wherein the upper airway tissue collapse condition includes a first tissue collapse at a first location within the patient's upper airway and a second tissue collapse at a second location within the patient's upper airway, wherein the delivering of the electrical stimulation corresponds to a mitigation of the first tissue collapse at the first location, and wherein the tightening of the patient's upper airway tissue corresponds to a mitigation of the second tissue collapse at the second location. 25. A method of treating an upper airway condition of a patient, the method comprising: implanting a first device in the upper airway of the patient, the first device having a first end secured to a first portion of upper airway tissue coupled to the tongue of the patient and an opposing second end secured to a second portion of upper airway tissue coupled to at least one of the patient's soft palate, palatopharyngeus, and palatoglossus; and implanting a second device in the patient, the second device disposed to deliver an electrical stimulation signal to the patient's hypoglossal nerve to move the second portion of upper airway tissue via the first device. 26. A method of treating an upper airway condition of a patient, the method comprising: implanting first and second devices in the patient's neck to treat a collapsed portion of the patient's upper airway, the second device being a stimulation delivery device disposed and configured to deliver an electrical stimulation signal to cause a movement of the patient's tongue, the first device disposed and configured to convey the stimulated movement of the patient's tongue to the collapsed portion of the patient's upper airway, wherein to open the collapsed portion of the patient's upper airway; and maintaining the delivery of the stimulation signal during an inspiration cycle of the patient.
Kallok Michael J. (New Brighton MN) Markowitz H. Toby (Roseville MN), Airway feedback measurement system responsive to detected inspiration and obstructive apnea event.
Bardy, Gust H.; Cappato, Riccardo; Rissmann, William J.; Sanders, Gary H., Cardioverter-defibrillator having a focused shocking area and orientation thereof.
Schulman, Joseph H.; Weisner, Ralph M.; Canfield, David L.; Fey, Kate E.; Byers, Charles L., Electrically sensing and stimulating system for placement of a nerve stimulator or sensor.
Baru Fassio, Marcelo Daniel; Hoffer, Joaquin Andres; Calderon, Enric; Jenne, Gary Bernhard; Calderon, Albert, Fully implantable nerve signal sensing and stimulation device and method for treating foot drop and other neurological disorders.
Strother, Robert B.; Mrva, Joseph J.; Thrope, Geoffrey B., Implantable pulse generator for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue.
Strother,Robert B.; Mrva,Joseph J.; Thrope,Geoffrey B., Implantable system and methods for acquisition and processing of electrical signals from muscles and/or nerves and/or central nervous system tissue.
Pohndorf Peter J. (Stillwater MN) Lessar Joseph F. (Coon Rapids MN) Upton James E. (New Brighton MN) Cobian Kenneth E. (St. Anthony MN), Medical electrical lead having sigmoidal conductors and non-circular lumens.
Durand, Dominique; Sahin, Mesut; Haxhiu, Musa A., Method and apparatus for closed-loop stimulation of the hypoglossal nerve in human patients to treat obstructive sleep apnea.
Testerman Roy L. (New Hope MN) Erickson Donald J. (Plymouth MN) Bierbaum Ralph W. (Coon Rapids MN), Method and apparatus for detecting and treating obstructive sleep apnea.
Cho, Yong K.; Ning, Steven L.; Mongeon, Luc R.; Davie, Scott W.; Sheldon, Todd J.; Erickson, Mark K.; Markowitz, H. Toby, Method and apparatus for detecting respiratory disturbances.
Testerman Roy L. (New Hope MN) Erickson Donald J. (Plymouth MN), Method and apparatus for providing a respiratory effort waveform for the treatment of obstructive sleep apnea.
Freed Marcy L. ; Tucker Howard, Method and apparatus for treating oropharyngeal respiratory and oral motor neuromuscular disorders with electrical stimulation.
Hill, Michael R. S.; Jonkman, Kenneth R., Method and device for electronically controlling the beating of a heart using venous electrical stimulation of nerve fibers.
W.ang.rd, Leif, Method for identifying respiration attempts by analyzing neuroelectrical signals, and respiration detector and respiratory aid system operating according to the method.
Milo Charles F. ; Selmon Matthew R. ; Hill Richard E. ; Co Fred H. ; French Ronald G., Methods and apparatus for crossing total occlusions in blood vessels.
Winthrop Neil (12A Amherst Ct. Royal Palm Beach FL 33411) Bayron Harry (7439 Pioneer Rd. West Palm Beach FL 33413), Nasal CPAP/Cannula and securement apparatus.
Bolea, Stephen L.; Hoegh, Thomas B.; Persson, Bruce J.; Atkinson, Robert E.; Mazar, Scott T., Obstructive sleep apnea treatment devices, systems and methods.
Tanagho Emil A. (San Rafael CA) Schmidt Richard A. (San Rafael CA) Gleason Curtis A. (Palo Alto CA) Lue Tom F. (Millbrae CA), Surgically implantable peripheral nerve electrode.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.