로그인시 본인확인과정이 필요할 수 있습니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기
| 국가/구분 | United States(US) Patent 등록 |
|---|---|
| 국제특허분류(IPC7판) |
|
| 출원번호 | US-0463444 (2014-08-19) |
| 등록번호 | US-9234864 (2016-01-12) |
| 발명자 / 주소 |
|
| 출원인 / 주소 |
|
| 대리인 / 주소 |
|
| 인용정보 | 피인용 횟수 : 0 인용 특허 : 454 |
A sensor designed to determine the amount and concentration of analyte in a sample having a volume of less than about 1 μL. The sensor has a working electrode coated with a non-leachable redox mediator. The redox mediator acts as an electron transfer agent between the analyte and the electrode. In a
A sensor designed to determine the amount and concentration of analyte in a sample having a volume of less than about 1 μL. The sensor has a working electrode coated with a non-leachable redox mediator. The redox mediator acts as an electron transfer agent between the analyte and the electrode. In addition, a second electron transfer agent, such as an enzyme, can be added to facilitate the electrooxidation or electroreduction of the analyte. The redox mediator is typically a redox compound bound to a polymer. The preferred redox mediators are air-oxidizable. The amount of analyte can be determined by coulometry. One particular coulometric technique includes the measurement of the current between the working electrode and a counter or reference electrode at two or more times. The charge passed by this current to or from the analyte is correlated with the amount of analyte in the sample. Other electrochemical detection methods, such as amperometric, voltammetric, and potentiometric techniques, can also be used. The invention can be used to determine the concentration of a biomolecule, such as glucose or lactate, in a biological fluid, such as blood or serum. An enzyme capable of catalyzing the electrooxidation or electroreduction of the biomolecule is provided as a second electron transfer agent.
1. A method for determining a concentration of an analyte in a body fluid of a patient, comprising the steps of: transporting a body fluid sample of the patient into a sample chamber of a test strip, the sample chamber comprising a working electrode and a reference electrode and/or a counter electro
1. A method for determining a concentration of an analyte in a body fluid of a patient, comprising the steps of: transporting a body fluid sample of the patient into a sample chamber of a test strip, the sample chamber comprising a working electrode and a reference electrode and/or a counter electrode, wherein the sample chamber has a volume of 1 μl or less; anddetermining the concentration of the analyte in the body fluid sample by measuring the charge passed through the working electrode over a period of time of within 1 minute after transporting the body fluid. 2. The method of claim 1, wherein the sample chamber has a volume of 0.5 μl or less. 3. The method of claim 1, wherein the sample chamber has a volume of 0.2 μl or less. 4. The method of claim 1, wherein the sample chamber has a volume of 0.1 μl or less. 5. The method of claim 1, wherein the sample chamber comprises a counter electrode and wherein the working electrode and the counter electrode are a facing electrode pair. 6. The method of claim 1, wherein the test strip further includes an enzyme on the working electrode. 7. The method of claim 6, wherein the enzyme is glucose oxidase or glucose dehydrogenase. 8. The method of claim 1, wherein an enzyme is immobilized on the working electrode. 9. The method of claim 1, wherein the test strip further includes a redox mediator on the working electrode. 10. The method of claim 9, wherein the redox mediator is immobilized on the working electrode. 11. The method of claim 9, wherein the redox mediator is an air-oxidizable redox mediator. 12. The method of claim 9, wherein the redox mediator carries electrons directly to the working electrode. 13. The method of claim 9, wherein the redox mediator comprises an osmium complex, a ferrocyanide, or a ferricyanide. 14. The method of claim 1, wherein the analyte is glucose. 15. The method of claim 1, wherein the working electrode is constructed of a material selected from gold, carbon, platinum, ruthenium dioxide and palladium. 16. The method of claim 1, wherein the working electrode is separated from the counter or reference electrode by a distance of less than 200 micrometer.
해당 특허가 속한 카테고리에서 활용도가 높은 상위 5개 콘텐츠를 보여줍니다.
더보기 버튼을 클릭하시면 더 많은 관련자료를 살펴볼 수 있습니다.
Copyright KISTI. All Rights Reserved.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.