최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
---|---|
국제특허분류(IPC7판) |
|
출원번호 | US-0529614 (2006-09-29) |
등록번호 | US-9380974 (2016-07-05) |
발명자 / 주소 |
|
출원인 / 주소 |
|
대리인 / 주소 |
|
인용정보 | 피인용 횟수 : 4 인용 특허 : 338 |
An arrangement includes a housing, a plurality of sampling and analysis sites contained within the housing, each of the sampling and analysis sites having a skin-penetration member having a first end configured to pierce the skin, and an inner lumen in communication with the first end, an actuator o
An arrangement includes a housing, a plurality of sampling and analysis sites contained within the housing, each of the sampling and analysis sites having a skin-penetration member having a first end configured to pierce the skin, and an inner lumen in communication with the first end, an actuator operatively associated with the skin-penetration member, and an analyte quantification member in fluid communication with the inner lumen of the skin-penetration member. Integrated devices including such arrangements are also described.
1. An arrangement comprising: a housing;a plurality of sampling and analysis sites contained within the housing, each of the sampling and analysis sites comprising: a skin-penetration member having a first end configured to pierce skin, and an inner lumen in communication with the first end;a spring
1. An arrangement comprising: a housing;a plurality of sampling and analysis sites contained within the housing, each of the sampling and analysis sites comprising: a skin-penetration member having a first end configured to pierce skin, and an inner lumen in communication with the first end;a spring actuator configured to drive the skin-penetration member into skin of a user;a hub, wherein the skin-penetration member and the spring actuator are attached to the hub;a pin, wherein the hub is configured to rotate around the pin; andan analyte quantification member disposed on or within the hub, wherein the analyte quantification member is in fluid communication with the inner lumen of the skin-penetration member. 2. The arrangement of claim 1, wherein the housing further comprises a plurality of footprints, wherein each footprint surrounds a respective aperture and is configured to be applied to a sampling site on the skin of the user, and wherein the spring actuator of at least one of the plurality of sampling and analysis sites is configured to drive the skin-penetration member of the same sampling and analysis site through at least one of the respective apertures. 3. The arrangement of claim 2, wherein each footprint has an opening, the opening having a diameter or major dimension of 3-8 mm. 4. The arrangement of claim 2, wherein each footprint comprises an elastomeric seal. 5. The arrangement of claim 1, wherein at least a portion of the housing is transparent and provides optical communication with each analyte quantification member. 6. The arrangement of claim 1, wherein the skin-penetration member of at least one of the sampling and analysis sites comprises a microneedle. 7. The arrangement of claim 1, wherein the spring actuator of at least one of the sampling and analysis sites comprises a torsional spring configured to urge the skin-penetration member along an arcuate path. 8. The arrangement of claim 7, wherein the skin penetration member of the at least one sampling and analysis site that comprises a torsional spring is configured to obstruct a wound opening in the skin of the user after the torsional spring moves from a compressed position to a relaxed position. 9. The arrangement of claim 7, wherein at least one of the sampling and analysis sites that comprises a torsional spring lacks a positive stop to limit the penetration depth of the skin-penetration member of the respective sampling and analysis site. 10. The arrangement of claim 1, wherein the hub of at least one of the sampling and analysis sites comprises at least one of a groove or projections, and wherein the at least one of the groove or projections is configured to releasably lock the hub against movement by the spring actuator. 11. The arrangement of claim 1 further comprising a trigger configured to release the hub of at least one of the sampling and analysis sites, and wherein the respective spring actuator of the at least one sampling and analysis site is configured to move the hub when the hub is released. 12. The arrangement of claim 11, wherein the trigger comprises a moveable arm, and wherein the hub of the at least one sampling and analysis site comprises a groove and the respective spring actuator of the at least one sampling and analysis site comprises a spring having a leg releasably mounted in the groove, and wherein the moveable arm is configured to displace the leg from the groove and the spring actuator of the at least one sampling and analysis site is configured to move the hub of the at least one sampling and analysis site when the moveable arm displaces the leg from the groove. 13. The arrangement of claim 12, wherein the moveable arm comprises an angular or arcuate ramp surface. 14. The arrangement of claim 12, wherein the housing comprises an opening for passage of the moveable arm, wherein the opening comprises a seal and wherein the seal comprises a solid flexible membrane, an apertured membrane in combination with a secondary seal, or a piercable membrane. 15. The arrangement of claim 11, wherein the trigger comprises a severable wire or fuse. 16. The arrangement of claim 1, wherein the arrangement is a disposable cartridge. 17. The arrangement of claim 1, further comprising a barcode or a chip, wherein the barcode or the chip comprises readable information and wherein the barcode or the chip is contained on or within the housing. 18. The arrangement of claim 17, wherein the readable information comprises at least one of: calibration information, algorithm information, software code, and accuracy verification information. 19. The arrangement of claim 1, wherein at least one of the sampling and analysis sites comprises a control corresponding to a predetermined analyte concentration. 20. The arrangement of claim 1, further comprising at least one light source and detector, wherein the at least one light source and detector are configured to interrogate each analyte quantification member. 21. The arrangement of claim 20, wherein the analyte quantification members are configured to move to facilitate the creation of a list of unused analyte quantification members or to align an analyte quantification member with the at least one light source and detector for analysis. 22. The arrangement of claim 20, wherein the at least one light source and detector are configured to move to create a list of unused analyte quantification members or to align an analyte quantification member with the at least one light source and detector for analysis. 23. The arrangement of claim 22, wherein the at least one light source and detector are mounted on a moveable indexing arm. 24. The arrangement of claim 20, the arrangement further comprising a plurality of light transmitting elements in optical communication with the at least one light source and the analyte quantification members, wherein the at least one light source and detector and the analyte quantification members are fixed relative to each other, wherein the detector is positioned to receive light reflected off each analyte quantification member, and wherein the detector comprises a plurality of sections, each section designated to receive light reflected off of a respective one of the analyte quantification members. 25. The arrangement of claim 20, wherein the at least one light source and detector, and the analyte quantification members, are fixed relative to each other, and further comprising a plurality of light transmitting elements in optical communication with the at least one light source and analyte quantification members, wherein the detector comprises a plurality of discrete detector elements, and wherein each of the plurality of discrete detector elements is positioned to receive light reflected off of a respective one of the analyte quantification members. 26. The arrangement of claim 1, wherein the spring actuator of at least one of the sampling and analysis sites is configured to move the hub and the skin-penetration member in an arcing movement toward the skin of the user. 27. The arrangement of claim 1, wherein the arrangement further comprises a cartridge and the cartridge comprises the plurality of sampling and analysis sites. 28. The arrangement of claim 1, wherein the arrangement has an annular shape. 29. An integrated body fluid sampling and analysis device comprising the arrangement of claim 1. 30. The integrated device of claim 29, further comprising a detector in optical communication with at least one analyte quantification member. 31. The integrated device of claim 30, wherein the detector comprises at least one complementary metal oxide semiconductor (CMOS)-based detector element. 32. The integrated device of claim 30, wherein the detector comprises at least one linear or area array of CMOS-based detector elements. 33. The integrated device of claim 30, wherein the housing is configured to move to present a new skin-penetration member, spring actuator and analyte quantification member after the performance of a preceding sampling and analysis event. 34. The integrated device of claim 29, wherein the device is configured for one or more of hand-held operation and operation while being worn. 35. The integrated device of claim 29, wherein the device is configured for one or more of fingertip sampling and alternate site sampling. 36. An arrangement comprising: a housing;a plurality of sampling and analysis sites contained within the housing, each of the sampling and analysis sites comprising: a skin-penetration member having a first end configured to pierce skin, and an inner lumen in communication with the first end;an actuator configured to drive the skin-penetration member into skin of a user;a hub, wherein the skin-penetration member and the actuator are attached to the hub;a pin, wherein the hub is configured to rotate around the pin; andan analyte quantification member disposed on or within the hub, wherein the analyte quantification member is in fluid communication with the inner lumen of the skin-penetration member. 37. The arrangement of claim 36, wherein the arrangement further comprises a cartridge and the cartridge comprises the plurality of sampling and analysis sites. 38. The arrangement of claim 36, wherein the actuator of at least one of the sampling and analysis sites is configured to move the hub and the skin-penetration member in an arcing movement toward the skin of the user. 39. The arrangement of claim 36, wherein the arrangement has an annular shape. 40. The arrangement of claim 36, wherein the arrangement is a disposable cartridge.
Copyright KISTI. All Rights Reserved.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.