[특허]Methods for preparation of medical dressing containing antimicrobial agent

[미국특허] Methods for preparation of medical dressing containing antimicrobial agent 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61F-013/00 A61L-015/22 A61L-015/44 A61L-015/46
출원번호	US-0192937 (2014-02-28)
등록번호	US-9480770 (2016-11-01)
발명자 / 주소	Patel, Harish A.
출원인 / 주소	Covidien LP
인용정보	피인용 횟수 : 0 인용 특허 : 64

초록 ▼

A medical dressing containing an antimicrobial agent is disclosed. The medical dressing comprises a layered fabric comprising an inner layer of substantially hydrophilic material, an outer layer of substantially hydrophobic material on both sides of the inner layer; and an antimicrobial agent. The antimicrobial agent may be releasably impregnated into the fabric, coated on said fabric or a combination thereof. The antimicrobial agent may be a biguanide, such as polyhexamethylene biguanide (PHMB). The fabric inner layer material may be substantially a cellulose fiber, preferably substantially rayon, and the fabric outer layer material may be substantially polyester, e.g., a combination of textile matrix grade polyester fiber and amorphous binder grade polyester fiber. The fabric is preferably treated with an aqueous solution of surfactant and PHMB to have about 1500-3500 ppm of extractable PHMB.

대표청구항 ▼

1. A method of preparing a medical dressing comprising: forming a layered fabric consisting essentially of an inner layer of hydrophilic material, andouter layers of hydrophobic material on both sides of the inner layer; andimpregnating a biguanide antimicrobial agent into the inner layer. 2. The method according to claim 1 wherein the inner layer of hydrophilic material is rayon, and the outer layers of hydrophobic material are a combination of textile matrix grade polyester fiber and amorphous binder grade polyester fiber. 3. The method according to claim 2, wherein impregnating the biguanide antimicrobial agent comprises contacting the layered fabric with a solution having a surfactant and polyhexamethylene biguanide. 4. A method comprising forming a dressing consisting essentially of an inner layer of hydrophilic material, outer layers of hydrophobic material on both sides of the inner layer, and a biguanide antimicrobial agent, wherein the biguanide antimicrobial agent is releasably contained in the inner layer. 5. The method of claim 4, wherein the biguanide antimicrobial agent is polyhexamethylene biguanide. 6. The method of claim 5, wherein at least one outer layer is a combination of textile matrix grade polyester fiber and amorphous binder grade polyester fiber. 7. The method of claim 4, wherein the hydrophilic material is rayon, and the hydrophobic material is a combination of textile matrix grade polyester fiber and amorphous binder grade polyester fiber. 8. A method of preparing a sponge comprising forming layered plies of a substrate consisting essentially of at least one inner layer of hydrophilic material, outer layers of hydrophobic material on both sides of the at least one inner layer, and a biguanide antimicrobial agent releasably contained in the inner layer. 9. The method of claim 8, wherein the biguanide antimicrobial agent is polyhexamethylene biguanide. 10. The method of claim 8, further comprising creating a cross-shaped incision at the center of the layered plies.

이 특허에 인용된 특허 (64) 인용/피인용 타임라인 분석

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[미국특허] Methods for preparation of medical dressing containing antimicrobial agent 원문보기