Short-wave infrared super-continuum lasers for early detection of dental caries
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
G01J-003/00
G01N-033/15
A61B-005/1455
A61B-005/00
G01J-003/10
G01J-003/28
G01J-003/453
G01N-021/359
A61B-005/145
G01N-033/49
H01S-003/30
G01J-003/14
G01J-003/18
출원번호
US-0651367
(2013-12-17)
등록번호
US-9500635
(2016-11-22)
국제출원번호
PCT/US2013/075736
(2013-12-17)
국제공개번호
WO2014/105521
(2014-07-03)
발명자
/ 주소
Islam, Mohammed N.
출원인 / 주소
OMNI MEDSCI, INC.
대리인 / 주소
Brooks Kushman P.C.
인용정보
피인용 횟수 :
3인용 특허 :
149
초록▼
A system and method for using near-infrared or short-wave infrared (SWIR) sources such as lamps, thermal sources, LED's, laser diodes, super-luminescent laser diodes, and super-continuum light sources for early detection of dental caries measure transmission and/or reflectance. In the SWIR wavelengt
A system and method for using near-infrared or short-wave infrared (SWIR) sources such as lamps, thermal sources, LED's, laser diodes, super-luminescent laser diodes, and super-continuum light sources for early detection of dental caries measure transmission and/or reflectance. In the SWIR wavelength range, solid, intact teeth may have a low reflectance or high transmission with very few spectral features while a carious region exhibits more scattering, so the reflectance increases in amplitude. The spectral dependence of the transmitted or reflected light from the tooth may be used to detect and quantify the degree of caries. Instruments for applying SWIR light to one or more teeth may include a C-clamp design, a mouth guard design, or hand-held devices that may augment other dental tools. The measurement device may communicate with a smart phone or tablet, which may transmit a related signal to the cloud, where additional value-added services are performed.
대표청구항▼
1. A diagnostic system comprising: a light source configured to generate an output optical beam, comprising: one or more semiconductor sources configured to generate an input beam;one or more optical amplifiers configured to receive at least a portion of the input beam and to deliver an intermediate
1. A diagnostic system comprising: a light source configured to generate an output optical beam, comprising: one or more semiconductor sources configured to generate an input beam;one or more optical amplifiers configured to receive at least a portion of the input beam and to deliver an intermediate beam to an output end of the one or more optical amplifiers;one or more optical fibers configured to receive at least a portion of the intermediate beam and to deliver at least the portion of the intermediate beam to a distal end of the one or more optical fibers to form a first optical beam;a nonlinear element configured to receive at least a portion of the first optical beam and to broaden a spectrum associated with the at least a portion of the first optical beam to at least 10 nanometers through a nonlinear effect in the nonlinear element to form the output optical beam with an output beam broadened spectrum; andwherein at least a portion of the output beam broadened spectrum comprises a short-wave infrared wavelength between approximately 1400 nanometers and approximately 2500 nanometers, and wherein at least a portion of the one of more fibers is a fused silica fiber with a core diameter less than approximately 400 microns;an interface device configured to receive a received portion of the output optical beam and to deliver a delivered portion of the output optical beam to a sample comprising enamel and dentine, wherein the delivered portion of the output optical beam is configured to generate a spectroscopy output beam from the sample; anda receiver configured to receive at least a portion of the spectroscopy output beam having a bandwidth of at least 10 nanometers and to process the portion of the spectroscopy output beam to generate an output signal based on a wavelength dependence of the spectroscopy output beam over the bandwidth of at least 10 nanometers. 2. The system of claim 1, wherein the wavelength dependence of the spectroscopy output beam is based at least in part on wavelength dependent scattering and water absorption characteristics of the sample. 3. The system of claim 1, wherein the bandwidth of the spectroscopy output beam is at least 100 nanometers, and the output signal is based on the wavelength dependence of the spectroscopy output beam over the bandwidth of at least 100 nanometers. 4. The system of claim 1, wherein the interface device further comprises a replaceable insert, and wherein the spectroscopy output beam is based on transmission, reflection or absorption of the sample. 5. The system of claim 1, wherein the receiver further comprises a wireless transmitter configured to communicate a wireless signal associated with the output signal to a network. 6. A measurement system comprising: a light source configured to generate an output optical beam, comprising:a plurality of semiconductor sources configured to generate an input optical beam;a multiplexer configured to receive at least a portion of the input optical beam and to form an intermediate optical beam;one or more fibers configured to receive at least a portion of the intermediate optical beam and to form the output optical beam;wherein the output optical beam comprises one or more optical wavelengths of between approximately 1400 nanometers and approximately 2500 nanometers;wherein the output optical beam has a bandwidth of at least 10 nanometers; andwherein at least a portion of the one or more fibers comprises a fused silica fiber with a core diameter less than approximately 400 microns;an interface device configured to receive a received portion of the output optical beam and to deliver a delivered portion of the output optical beam to a sample comprising enamel and dentine, wherein the delivered portion of the output optical beam is configured to generate a spectroscopy output beam from the sample; anda receiver configured to receive at least a portion of the spectroscopy output beam having a bandwidth of at least 10 nanometers and to process the portion of the spectroscopy output beam to generate an output signal based on a wavelength dependence of the spectroscopy output beam over the bandwidth of at least 10 nanometers. 7. The system of claim 6, wherein the light source comprises a super-continuum laser. 8. The system of claim 6, wherein the light source comprises a super-luminescent diode. 9. The system of claim 6, wherein the light source comprises a light emitting diode. 10. The system of claim 6, wherein the output signal is based at least in part on wavelength dependent scattering from the sample. 11. The system of claim 6, wherein the output signal is based at least in part on water absorption characteristics of the sample. 12. The system of claim 6, wherein the bandwidth of the spectroscopy output beam is at least 100 nanometers, and the output signal is based on the wavelength dependence of the spectroscopy output beam over the bandwidth of at least 100 nanometers. 13. The system of claim 6, wherein the spectroscopy output beam is based on transmission, reflection, or absorption of the sample. 14. The system of claim 6, wherein the interface device further comprises a replaceable insert. 15. The system of claim 6, wherein the output signal is configured to identify dental caries. 16. A method of measuring, comprising: generating an output optical beam, comprising:generating an input optical beam from a plurality of semiconductor sources;multiplexing at least a portion of the input optical beam and forming an intermediate optical beam; andguiding at least a portion of the intermediate optical beam using one or more fibers comprising fused silica with a core diameter less than 400 microns and forming the output optical beam, wherein the output optical beam comprises one or more optical wavelengths between 1400 nanometers and 2500 nanometers; andbroadening the spectrum of at least a portion of the intermediate optical beam to at least 10 nanometers to form the output optical beam with an output beam broadened spectrum;receiving a received portion of the output optical beam and delivering a delivered portion of the output optical beam to a sample, wherein the sample comprises enamel and dentine;generating a spectroscopy output beam having a bandwidth of at least 10 nanometers from the sample;receiving at least a portion of the spectroscopy output beam having a bandwidth of at least 10 nanometers; andprocessing the portion of the spectroscopy output beam and generating an output signal based on a wavelength dependence of the spectroscopy output beam over the bandwidth of at least 10 nanometers. 17. The method of claim 16, wherein the wavelength dependence of the spectroscopy output beam is based at least in part on wavelength dependent transmission, reflection, or absorption of the sample. 18. The method of claim 16, further comprising communicating a wireless signal associated with the output signal to a network.
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