[특허]Use of TNFα inhibitor

[미국특허] Use of TNFα inhibitor 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	C07K-016/24 A61K-039/395 A61K-009/00
출원번호	US-0173191 (2016-06-03)
등록번호	US-9512216 (2016-12-06)
발명자 / 주소	Hoffman, Rebecca S. Weinberg, Mark Taylor, Lori K. Chartash, Elliot K. Yan, Philip Granneman, George R.
출원인 / 주소	AbbVie Biotechnology Ltd.
대리인 / 주소	Foley Hoag LLP
인용정보	피인용 횟수 : 1 인용 특허 : 75

초록 ▼

The invention describes methods of treating erosive polyarthritis comprising administering a TNFα antibody, or antigen-binding portion thereof. The invention also describes a method for testing the efficacy of a TNFα antibody, or antigen-binding portion thereof, for the treatment of erosive polyarth

대표청구항 ▼

1. A method for treating moderate to severe chronic plaque psoriasis, comprising subcutaneously administering to an adult patient having moderate to severe chronic plaque psoriasis an initial dose of 80 mg of adalimumab, followed by 40 mg of adalimumab every other week starting one week after said first dosing, wherein the patient achieves at least Psoriasis Area and Severity Index (PASI) 75 response at week 12 of the treatment. 2. The method of claim 1, wherein at least 5% body surface area (BSA) of the patient is affected by the moderate to severe chronic plaque psoriasis. 3. The method of claim 1, wherein adalimumab is comprised in pre-filled syringes for subcutaneous injection. 4. The method of claim 1, wherein adalimumab is formulated in a pharmaceutical composition and at a concentration of 50 mg/ml. 5. The method of claim 3, wherein adalimumab is formulated in a pharmaceutical composition and at a concentration of 50 mg/ml. 6. The method of claim 2, wherein adalimumab is comprised in pre-filled syringes for subcutaneous injection. 7. The method of claim 2, wherein adalimumab is formulated in a pharmaceutical composition and at a concentration of 50 mg/ml. 8. The method of claim 6, wherein adalimumab is formulated in a pharmaceutical composition and at a concentration of 50 mg/ml. 9. A method for treating moderate to severe chronic plaque psoriasis, comprising subcutaneously administering to an adult patient having moderate to severe chronic plaque psoriasis an initial dose of 80 mg of adalimumab, followed by 40 mg of adalimumab every other week starting one week after said first dosing. 10. The method of claim 9, wherein at least 5% body surface area (BSA) of the patient is affected by the moderate to severe chronic plaque psoriasis. 11. The method of claim 9, wherein adalimumab is comprised in pre-filled syringes for subcutaneous injection. 12. The method of claim 9, wherein adalimumab is formulated in a pharmaceutical composition and at a concentration of 50 mg/ml. 13. The method of claim 11, wherein adalimumab is formulated in a pharmaceutical composition and at a concentration of 50 mg/ml. 14. The method of claim 10, wherein adalimumab is comprised in pre-filled syringes for subcutaneous injection. 15. The method of claim 10, wherein adalimumab is formulated in a pharmaceutical composition and at a concentration of 50 mg/ml. 16. The method of claim 15, wherein adalimumab is formulated in a pharmaceutical composition and at a concentration of 50 mg/ml.

이 특허에 인용된 특허 (75) 인용/피인용 타임라인 분석

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Salfeld, Jochen G.; Allen, Deborah J.; Hoogenboom, Hendricus R. J. M.; Kaymakcalan, Zehra; Labkovsky, Boris; Mankovich, John A.; McGuinness, Brian T.; Roberts, Andrew J.; Sakorafas, Paul; Schoenhaut,, Human antibodies that bind human TNFa.
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A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

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연합인증

[미국특허] Use of TNFα inhibitor 원문보기

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이 특허에 인용된 특허 (75) 인용/피인용 타임라인 분석

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[미국특허] Use of TNFα inhibitor 원문보기

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