An implant for filling and/or distracting a body region, particularly a non-soft tissue cavity, has a plurality of segments wherein at least two of the segments are flexibly connected. The segments have a crush-strength sufficient to create and/or maintain the distraction of two or more non-soft tis
An implant for filling and/or distracting a body region, particularly a non-soft tissue cavity, has a plurality of segments wherein at least two of the segments are flexibly connected. The segments have a crush-strength sufficient to create and/or maintain the distraction of two or more non-soft tissue body surfaces, and to maintain the stability of the body region. The implant may be inserted into a cavity by an applicator having a cannula with a distal opening, and a rotary driver for applying force to move the implant within the cannula.
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1. An implant for insertion into a cavity in a body tissue, comprising: a plurality of flexibly connected segments, each segment being flexibly connected to an immediately adjacent segment by a flexible connecting member configured to transmit motion between immediately adjacent segments in a manner
1. An implant for insertion into a cavity in a body tissue, comprising: a plurality of flexibly connected segments, each segment being flexibly connected to an immediately adjacent segment by a flexible connecting member configured to transmit motion between immediately adjacent segments in a manner enabling directional filling of the cavity with the implant, and the flexible connecting member including biological properties including at least one of medicinal properties, antibiotic properties, analgesic properties, anticoagulant properties, bone growth enhancing properties, or cell or gene therapieswherein at least some of the segments are frangible and configured to rupture upon engagement with the body tissue during insertion. 2. The implant of claim 1, one or more of the segments having a medicinal agent including a bone-growth promoting agent. 3. The implant of claim 2, the medicinal agent including at least one of a bone derived growth factor (BDGF), a bone morphogenetic protein (BMP), an antibacterial agent, an antiviral agent, a vascularizing agent, an analgesic, an anticoagulant, a cell therapeutic agent, and a gene therapeutic agent. 4. The implant of claim 1, comprising a flexible tube having an inner region, the segments being arranged within the inner region. 5. The implant of claim 4, the flexible tube having a first dimension located at each of the segments and a second dimension located between adjacent pairs of segments, the first dimension being greater than the second dimension so that the flexible tube has an undulating shape. 6. The implant of claim 1, each of the segments including a pellet secured to the flexible connecting member in such a manner that the pellet is not rotatable relative to the flexible connecting member. 7. The implant of claim 1, each of the pellets including at least one of: (a) a hole therethrough through which the associated flexible connecting member is threaded, (b) one or more attachments sites to which the associated flexible connecting member is tied or otherwise attached, (c) one of a track or a groove that mates to the associated flexible connecting member, (d) an adhesive attaching the pellet to the associated flexible connecting member, or (e) a crimped or swaged attachment to the flexible connecting member. 8. The implant of claim 1, each of the segments having a compressive strength greater than about 20 MPa. 9. The implant of claim 1, at least some of the segments being porous to facilitate tissue in-growth. 10. The implant of claim 1, wherein at least some of the segments have a diameter within a range of 1 to 10 mm. 11. The implant of claim 1, comprising a fluent settable agent having biological properties. 12. The implant of claim 1, comprising a fluent material that does not harden after the implant is inserted into the cavity in the body tissue. 13. The implant of claim 1, the implant being insertable into at least one of a bone, bone marrow, a vertebral body, an intervertebral body, a spinal disk, a tibial plateau, a femoral head, a hip bone, a ligament, cartilage, scar tissue, mineralized tissue, calcified tissue, a tumor, a cyst or a tissue cavity having at least one hard surface. 14. The implant of claim 1, the implant being configured to distract the cavity in the body tissue. 15. The implant of claim 1, one or more of the segments having one of a spherical shape, a cylindrical shape, a bullet shape, a conical shape, a rectangular shape, or a polygonal shape. 16. An implant for insertion into a cavity in a body tissue, comprising: a plurality of flexibly connected segments, each segment being flexibly connected to an immediately adjacent segment by a flexible connecting member configured to transmit motion between immediately adjacent segments in a manner enabling directional filling of the cavity with the implant, and the flexible connecting member including biological properties including at least one of medicinal properties, antibiotic properties, analgesic properties, anticoagulant properties, bone growth enhancing properties, or cell or gene therapies;a flexible tube having an inner region, the segments being arranged with in the inner region; andat least one of the segments possessing a plurality of protrusions that perforate the flexible tube during insertion of the implant into the cavity of the implant into the cavity.
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