[미국특허]
Silver nanoplate compositions and methods
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61K-033/38
A61K-009/51
A61L-027/00
C09D-125/06
C09D-129/04
C09D-139/06
C08K-003/28
C08K-003/36
C08K-003/38
C08K-005/092
C08K-005/1535
A61K-047/24
A61K-047/32
B22F-001/00
B22F-001/02
출원번호
US-0947508
(2015-11-20)
등록번호
US-9526745
(2016-12-27)
발명자
/ 주소
Oldenburg, Steven J.
Miranda, Martin
Sebba, David S.
Harris, Todd J.
출원인 / 주소
nanoComposix, Inc.
대리인 / 주소
Knobbe, Martens, Olson & Bear, LLP
인용정보
피인용 횟수 :
0인용 특허 :
135
초록▼
Embodiments of the present invention relate to methods for preparing high optical density solutions of nanoparticle, such as nanoplates, silver nanoplates or silver platelet nanoparticles, and to the solutions and substrates prepared by the methods. The process can include the addition of stabilizin
Embodiments of the present invention relate to methods for preparing high optical density solutions of nanoparticle, such as nanoplates, silver nanoplates or silver platelet nanoparticles, and to the solutions and substrates prepared by the methods. The process can include the addition of stabilizing agents (e.g., chemical or biological agents bound or otherwise linked to the nanoparticle surface) that stabilize the nanoparticle before, during, and/or after concentration, thereby allowing for the production of a stable, high optical density solution of silver nanoplates. The process can also include increasing the concentration of silver nanoplates within the solution, and thus increasing the solution optical density.
대표청구항▼
1. A process for making concentrated silver nanoplates that preserve shape post-concentration while increasing optical density, the process comprising: adding a stabilizing agent to a pre-concentrated solution,wherein the pre-concentrated solution comprises silver nanoplates,wherein each of the silv
1. A process for making concentrated silver nanoplates that preserve shape post-concentration while increasing optical density, the process comprising: adding a stabilizing agent to a pre-concentrated solution,wherein the pre-concentrated solution comprises silver nanoplates,wherein each of the silver nanoplates has a plate shape,wherein the pre-concentrated solution has a peak optical density at a first wavelength;wherein the stabilizing agent comprises a polymer derivatized with sulfonate and a molecule that comprises an amine or thiol chemical group; andincreasing a concentration of the silver nanoplates in the pre-concentrated solution to generate a concentrated solution,wherein the concentrated solution has a peak optical density at a second wavelength,wherein the first wavelength is substantially the same as the second wavelength,wherein the peak optical density of the concentrated solution is greater than the peak optical density of the pre-concentrated solution, andwherein at least a portion of the silver nanoplates in the pre-concentrated solution retain the plate shape in the concentrated solution. 2. The process of claim 1, wherein the amine chemical group comprises at least one of the group consisting of: an aminopropyltriethoxysilane (APTES) and an amine moiety. 3. The process of claim 1, wherein the thiol chemical group comprises at least one of the group consisting of: a lipoic acid, a mercaptohexadecanoic acid, a mercaptoundecanoic acid, and a dihydrolipoic acid. 4. The process of claim 1, wherein the peak optical density of the concentrated solution is at least ten times higher than the peak optical density of the pre-concentrated solution,wherein the peak optical density of the concentrated solution is at least 100 cm−1,wherein the second wavelength of the concentrated solution is in a range between 300 nm and 1500 nm, andwherein at least one optical property of the concentrated solution is substantially the same as the pre-concentrated solution in that the peak optical density of the pre-concentrated solution and the peak optical density of the concentrated solution occurs at substantially the same wavelength, andwherein the portion of the silver nanoplates that retain the plate shape is greater than 90% in the concentrated solution. 5. The process of claim 1, wherein the silver nanoplates are prepared via a seed mediated growth mechanism,wherein the seed mediated growth mechanism comprises: combining citrate, polystyrene sodium sulfonate (PSSS), and sodium borohydride in a first solution,adding silver nitrate to the first solution to form a seed solution,adding a portion of the seed solution to a second solution, wherein the second solution comprises ascorbic acid, andadding silver nitrate to the second solution to form the pre-concentrated solution. 6. The process of claim 1, wherein increasing the concentration is performed using a filter membrane with pores with a molecular weight cutoff in a range between 10 kDa and 0.05 micron,wherein the peak optical density of the concentrated solution is at least ten times higher than the peak optical density of the pre-concentrated solution,wherein the peak optical density of the concentrated solution is at least 100 cm−1. 7. The process of claim 1, further comprising coating the silver nanoplates with silica, wherein coating the silver nanoplates with silica comprises: adding ethanol to the pre-concentrated solution,adding a base to the pre-concentrated solution, andadding a silane to the pre-concentrated solution. 8. The process of claim 1, wherein the polymer derivatized with sulfonate comprises polystyrene sodium sulfonate. 9. The process of claim 1, further comprising forming a metal oxide shell on the surface of the silver nanoplate. 10. The process of claim 9, wherein the metal oxide shell is any of the group consisting of: a silica shell and a titanium dioxide shell, wherein the metal oxide shell has a thickness in a range between 1 nm to 100 nm. 11. The process of claim 1, wherein the second wavelength is within 10% of the first wavelength. 12. The process of claim 1, wherein the portion of the concentrated silver nanoplates that retain the plate shape after increasing the concentration is greater than 80%. 13. The process of claim 1, wherein the pre-concentrated solution is centrifuged. 14. The process of claim 1, where the pre-concentrated solution is incubated with a substrate, wherein the substrate comprises a fiber. 15. A composition comprising: a plurality of silver nanoplates in a solution comprising an optical density,wherein the silver nanoplates comprise a coating on a surface of the silver nanoplates,wherein the optical density is greater than 100 cm−1, andwherein the coating comprises polystyrene sodium sulfonate and at least one agent selected from the group consisting of: an amine-containing molecule and a thiol-containing molecule,wherein the coating further comprises a metal oxide shell,wherein the metal oxide shell is any of the group consisting of: a silica shell and a titanium dioxide shell,wherein the metal oxide shell has a thickness in a range between 1 nm to 100 nm. 16. The composition of claim 15, wherein the coating comprises said amine-containing molecule, wherein the amine-containing molecule comprises at least one of the group consisting of: an aminopropyltriethoxysilane (APTES) and an amine moiety. 17. The composition of claim 15, wherein the coating comprises said thiol-containing molecule, wherein the thiol-containing molecule comprises at least one of the group consisting of: a lipoic acid, a mercaptohexadecanoic acid, a mercaptoundecanoic acid, and a dihydrolipoic acid. 18. The composition of claim 15, wherein the metal oxide shell is the silica shell.
Stephen T. Hobson ; Ernest H. Braue ; Erich K. Lehnert ; Kenneth J. Klabunde ; Shawn Decker ; Craig L. Hill ; Jeffrey Rhule ; Eric Boring ; Olga Koper, Active topical skin protectants using combinations of reactive nanoparticles and polyoxometalates or metal salts.
Stephen T. Hobson ; Ernest H. Braue, Jr. ; Erich K. Lehnert ; Kenneth J. Klabunde ; Olga P. Koper ; Shawn Decker, Active topical skin protectants using reactive nanoparticles.
Martin, Guenaelle; Themens, Agnès, Anhydrous cosmetic compositions comprising at least one polymeric gelling agent, at least one non-volatile oil, and poly(methyl methacrylate) particles.
Forestier Serge (Claye-Souilly FRX) Hansenne Isabelle (Paris FRX), Cosmetic composition containing a mixture of metal oxide nanopigments and melanine pigments.
Le Bras Veronique,FRX ; Gabin Philippe,FRX, Cosmetic composition intended for making up the skin, process for its preparation and make-up product obtained from sai.
Wada, Koichi; Ishii, Nobuaki; Irie, Mitsuharu; Sekiguchi, Kazuo; Takama, Michihiro, Cosmetic preparation, surface-hydrophobized silica-coated metal oxide particles, sol of silica-coated metal oxide, and processes for producing these.
Crotty Brian Andrew ; Miner Philip Edward ; Johnson Anthony ; Znaiden Alexander Paul ; Corey Joseph Michael ; Vargas Anthony ; Meyers Alan Joel ; Lange Beth Anne, Delivery of skin benefit agents via adhesive strips.
Weaver, James C.; Anderson, R. Rox; Herndon, Terry O; Gowrishankar, T. R.; Gift, Elizabeth A.; Gonzalez, Salvador, Localized molecular and ionic transport to and from tissues.
Tankovich Nikolai I. ; Dasse Kurt A. ; Fine David H. ; Fairchild Paul W. ; Zhao Zhong-Quan ; Lefebvre Mike ; Lee ; Jr. John ; Rolfe Jonathan L. ; Murrell Susan ; Hunter ; II Allen ; Reynolds Amanda J, Methods and devices for inhibiting hair growth and related skin treatments.
Oldenburg,Steven J.; Averitt,Richard D.; Halas,Nancy J., Nanoparticle comprising nanoshell of thickness less than the bulk electron mean free path of the shell material.
Bara Isabelle (Paris FRX) Mellul Myriam (L\Hay Les Roses FRX), New cosmetic or dermopharmaceutical compositions in the form of aqueous gels modified by the addition of expanded micros.
Halas, Nancy J.; Wang, Hui; Nordlander, Peter J.; Wu, Yanpeng, Nonconcentric nanoshells with offset core in relation to shell and method of using the same.
Candau Didier,FRX ; Hansenne Isabelle, Photoprotective cosmetic compositions containing a metal oxide nanopigment and an acrylic terpolymer, and use of these compositions for protecting keratinous material against ultraviolet radiation.
Forestier Serge,FRX ; Hansenne Isabelle,FRX, Screening cosmetic composition comprising one nanopigment of metallic oxide and one fat-soluble screening polymer.
Forestier Serge,FRX ; Hansenne Isabelle,FRX, Screening cosmetic composition comprising one nanopigment of metallic oxide and one fat-soluble screening polymer.
Forestier Serge,FRX ; Hansenne Isabelle,FRX, Screening cosmetic composition comprising one nanopigment of metallic oxide and one fat-soluble screening polymer.
Chang, Tae Sun; Lee, Dong Koo; Kim, Tae Soon; Woo, Wan Je, Self-molding permanent agent and method for proceeding free-rod and free-band type permanent.
Minerath, III, Bernard Joseph; Otts, David Roland; Huard, Linda Susan; Tyrrell, David John; DiLuccio, Robert Cosmo; Akin, Frank Jerrel; Buhrow, Chantel Spring; Everhart, Dennis Stein; Nelson, Brenda , Substrate composition for sequestration of skin irritants.
Jennifer L. West ; Scott R. Sershen ; Nancy J. Halas ; Steven J. Oldenburg ; Richard D. Averitt, Temperature-sensitive polymer/nanoshell composites for photothermally modulated drug delivery.
West, Jennifer L.; Sershen, Scott R.; Halas, Nancy J.; Oldenburg, Steven J.; Averitt, Richard D., Temperature-sensitive polymer/nanoshell composites for photothermally modulated drug delivery.
Harris, Todd James; Chen Kim, Alice Ann, Thermal treatment of a pilosebaceous unit with nanoparticles with coatings that facilitate selective removal from the skin surface.
Chen, Mei-Chin; Chen, Dong-Hwang; Wang, Kuan-Wen; Lai, Bo-Hung, Transdermal drug delivery patch and method of controlling drug release of the same by near-IR.
Lemann Patricia,FRX, Use of an indigoid compound in a cosmetic composition, in particular a make-up composition, in order to confer on it antimicrobial properties and the property of lengthy hold over time.
Dupuis Christine (Paris FRX) Dubief Claude (Le Chesnay FRX), Use of metal oxide nanopigments for protecting hair keratin against atmospheric attack, especially light, method of prot.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.