Guidable intravascular blood pump and related methods
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-001/12
A61M-025/09
A61M-001/10
출원번호
US-0239697
(2016-08-17)
등록번호
US-9545468
(2017-01-17)
발명자
/ 주소
Aboul-Hosn, Walid N.
Kanz, William R.
Baker, Bruce A.
출원인 / 주소
MAQUET Cardiovascular LLC
대리인 / 주소
Ronai, Abraham
인용정보
피인용 횟수 :
4인용 특허 :
137
초록▼
A cannula is provided with one or more pressure transducers for measuring fluid pressure interiorly or exteriorly of the cannula. The pressure transducers may be mounted integrally with the tubular wall defining the main lumen of the cannula, or they may comprise differential pressure transducers mo
A cannula is provided with one or more pressure transducers for measuring fluid pressure interiorly or exteriorly of the cannula. The pressure transducers may be mounted integrally with the tubular wall defining the main lumen of the cannula, or they may comprise differential pressure transducers mounted in dedicated lumens in communication with the main lumen. The pressure measurements from the transducers is used to determine fluid flow rate.
대표청구항▼
1. An intravascular blood pump system, comprising: an intravascular blood pump adapted to be guided to a predetermined location within the circulatory system of a patient by a guide wire and configured to provide left-heart support, the intravascular blood pump comprising a rotor having a rotor hub
1. An intravascular blood pump system, comprising: an intravascular blood pump adapted to be guided to a predetermined location within the circulatory system of a patient by a guide wire and configured to provide left-heart support, the intravascular blood pump comprising a rotor having a rotor hub tapering in the distal direction, at least one blade extending radially outward from the rotor hub,a catheter coupled to a proximal end of the intravascular blood pump, a purge lumen extending through the catheter and operatively arranged to deliver purge fluid towards the intravascular blood pump;a cannula coupled to a distal end of the intravascular blood pump, one or more first ports and one or more second ports establishing fluid communication between a lumen of the cannula and an exterior region of the cannula, wherein at least one first port is located in proximity to the rotor and at least one second port is spaced apart from and located distal to the at least one first port, the cannula is configured such that when the intravascular blood pump is positioned in the patient to provide left-heart support the distal end of the cannula and the at least one second port are positioned inside the patient's heart and the proximal end of the cannula and the at least one first port are positioned in the patient's aorta, the intravascular blood pump is configured to draw blood from the patient's heart into the at least one second port through the cannula lumen and out the at least one first port to provide left-heart support while the cannula is positioned across an aortic valve of the patient;an elongate lumen associated with the cannula and sized to slidably receive the guide wire and dimensioned such that the guide wire passes slidably and coaxially through the elongate lumen, the elongate lumen is sized smaller cross sectionally than the cannula lumen, both the elongate lumen and the cannula lumen not extending through the rotor hub, the intravascular blood pump system configured for the guide wire to extend proximally away from the intravascular blood pump, the guide wire not passing through the rotor hub or the catheter, and the guide wire extending out of the intravascular blood pump system in a distal direction through the elongate lumen;a pressure sensing element configured to sense pressure proximate the intravascular blood pump;a housing connected to a proximal end of the catheter; andfirst and second conduits each connected to the housing, at least one of the first conduit and second conduit in fluid communication with the purge lumen. 2. The intravascular blood pump system of claim 1 wherein the rotor further comprises a second blade extending radially from the rotor hub and wherein the hub has a distal end extending distally beyond a most distal portion of the blades. 3. The intravascular blood pump system of claim 1 wherein the housing is configured to have the purge fluid pass through it. 4. The intravascular blood pump system of claim 1 wherein the cannula is reinforced with a spiral wire. 5. The intravascular blood pump system of claim 1 wherein the pressure sensing element comprising at least one of a piezo-electric pressure sensing element and a strain gauge. 6. The intravascular blood pump system of claim 5 wherein the pressure sensing element further comprising a fluid column extending through the catheter. 7. The intravascular blood pump system of claim 1 wherein the pressure sensing element is used to determine a differential pressure. 8. The intravascular blood pump system of claim 1 further comprising a rotor shroud, a portion of the rotor shroud having an outer diameter matching an inner diameter of a proximal portion of the cannula. 9. The intravascular blood pump system of claim 1 further comprising a rotor shroud, motor assembly and a drive cable, the drive cable at least partially disposed within the catheter, wherein the motor assembly and drive cable are configured to drive the rotor,wherein the elongate lumen is proximal to the cannula and the motor assembly is configured to remain external to the patient, andwherein the intravascular blood pump system comprises a dual construction arrangement whereby the rotor is configured to be docked within the rotor shroud. 10. The intravascular blood pump system of claim 1 further comprising a rotor shroud, at least a portion of the rotor shroud having the same outer diameter as the cannula. 11. The intravascular blood pump system of claim 1 wherein the elongate lumen runs longitudinally through and is an integral extension of a wall of the cannula. 12. The intravascular blood pump system of claim 1 wherein the elongate lumen is a side lumen extending longitudinally but offset radially from a central axis of the cannula along at least a portion of the cannula. 13. The intravascular blood pump system of claim 1 wherein the elongate lumen is adapted to guide the guide wire through a distal end of the intravascular blood pump system. 14. The intravascular blood pump system of claim 1 wherein the elongate lumen is shorter in length than the cannula lumen. 15. The intravascular blood pump system of claim 1 wherein the purge lumen is a side lumen extending longitudinally through the catheter but offset radially from a central axis of the catheter. 16. The intravascular blood pump system of claim 1 further comprising a fluid delivery pump configured to deliver purge fluid through the purge lumen towards the intravascular blood pump. 17. The intravascular blood pump system of claim 16 wherein the fluid delivery pump is configured to deliver the purge fluid at a pressure that is both sufficient to avoid clotting of the patient's blood and that is higher than a blood pressure of the patient adjacent the intravascular blood pump. 18. The intravascular blood pump system of claim 1 wherein the elongate lumen is at least partially disposed within an outer surface of the cannula. 19. The intravascular blood pump system of claim 1 further comprising a rotor shroud disposed about the rotor and wherein a proximal portion of the cannula is disposed about a distal portion of the rotor shroud, the distal portion of the rotor shroud having an outer diameter smaller than a diameter of a more proximal portion of the rotor shroud. 20. The intravascular blood pump system of claim 1 wherein the intravascular blood pump system is configured for the guide wire to enter the intravascular blood pump system through one end of the elongate lumen and to exit the intravascular blood pump system through an opposite end of the elongate lumen. 21. The intravascular blood pump system of claim 1 wherein when the intravascular blood pump is positioned in the patient to provide left-heart support the elongate lumen lies wholly within the left ventricle. 22. An intravascular blood pump system, comprising: an intravascular blood pump adapted to be guided to a predetermined location within the circulatory system of a patient by a guide wire and configured to provide left-heart support, the intravascular blood pump comprising a rotor having a rotor hub tapering in the distal direction and a rotor shroud at least partially disposed about the rotor hub, at least one blade extending radially outward from the rotor hub, a distal end of the hub extending distally beyond a most distal portion of the at least one blade;a catheter coupled to a proximal end of the intravascular blood pump, a purge lumen extending through the catheter and operatively arranged to deliver purge fluid towards the intravascular blood pump;a cannula coupled to a distal end of the intravascular blood pump, a portion of the rotor shroud having an outer diameter matching an inner diameter of a proximal portion of the cannula, the proximal portion of the cannula disposed about a distal end of the rotor shroud, one or more first ports and one or more second ports establishing fluid communication between a lumen of the cannula and an exterior region of the cannula, wherein at least one first port is located in proximity to the rotor and at least one second port is spaced apart from and located distal to the at least one first port, the cannula is configured such that when the intravascular blood pump is positioned in the patient to provide left-heart support the distal end of the cannula and the at least one second port are positioned inside the patient's heart and the proximal end of the cannula and the at least one first port are positioned in the patient's aorta, the intravascular blood pump is configured to draw blood from the patient's heart into the at least one second port through the cannula lumen and out the at least one first port to provide left-heart support while the cannula is positioned across an aortic valve of the patient;an elongate lumen associated with the cannula and sized to slidably receive the guide wire and dimensioned such that the guide wire passes slidably and coaxially through the elongate lumen, the elongate lumen is sized smaller cross sectionally than the cannula lumen, both the elongate lumen and the cannula lumen not extending through the rotor hub, the intravascular blood pump system configured for the guide wire to extend proximally away from the intravascular blood pump, the guide wire not passing through the rotor hub or the catheter, and the guide wire extending out of the intravascular blood pump system in a distal direction through the elongate lumen;a pressure sensing element configured to sense pressure proximate the intravascular blood pump comprising a fluid column extending through the catheter;a housing connected to a proximal end of the catheter, the housing configured to have the purge fluid passing through it;first and second conduits each connected to the housing, at least one of the first conduit and second conduit in fluid communication with the purge lumen; anda fluid delivery pump configured to deliver purge fluid through at least one of the first and second conduits, and through the housing and the purge lumen towards the intravascular blood pump. 23. The intravascular blood pump system of claim 22 wherein the elongate lumen is shorter in length than the cannula lumen. 24. The intravascular blood pump system of claim 22 wherein the elongate lumen is at least partially disposed within an outer surface of the cannula and wherein the intravascular blood pump system is configured for the guide wire to enter the intravascular blood pump system through one end of the elongate lumen and to exit the intravascular blood pump system through an opposite end of the elongate lumen. 25. The intravascular blood pump system of claim 22 further comprising a motor assembly and a drive cable, the drive cable at least partially disposed within the catheter, wherein the motor assembly and drive cable are configured to drive the rotor,wherein the elongate lumen is proximal to the cannula and the motor assembly is configured to remain external to the patient, andwherein the intravascular blood pump system comprises a dual construction arrangement whereby the rotor is configured to be docked within the rotor shroud. 26. The intravascular blood pump system of claim 22 wherein when the intravascular blood pump is positioned in the patient to provide left-heart support both the elongate lumen and the tip member are wholly within the left ventricle.
Aboul-Hosn, Walid N; Kanz, William R; Zieglier, Roland W; McCrystle, Kelly J; Castor, Rosalind; deDios, Allan, Apparatus and methods for entering cavities of the body.
Andreas Bernard H. (Fremont CA) Glynn Brian A. (Sunnyvale CA) Evans Michael A. (Palo Alto CA) Farley Brian E. (Los Altos CA), Atherectomy catheter having flexible nose cone.
Bozeman ; Jr. Richard J. (Dickinson TX) Akkerman James W. (Houston TX) Aber Gregory S. (Houston TX) Damm George Arthur Van (Houston TX) Bacak James W. (Houston TX) Svejkovsky Paul A. (Webster TX) Ben, Axial pump.
Araki, Kenji; Oshikawa, Mitsuo; Anai, Hirohumi, Blood circulation auxiliary device using continuous blood flow pump and diagnosis device for blood circulation state in organism.
Aboul-Hosn Walid Najib ; Noor Sedig ; Kanz William Russell ; Guidera Michael ; Matheny Robert G. ; McCrystle Kelly J., Blood pump with sterile motor housing.
Jarvik Robert ; Alesi Daniel E. ; Klinger John F. ; Geiste Robert J. ; Day Steven R. ; Payea Keith ; Hammerquist Kenneth G. ; Stern Steven J. ; Kaczynski Francis X. ; Howansky Mark ; Cashin Deborah M, Circulatory support system.
Aboul-Hosn Walid N. ; Kanz William Russell ; McCrystle Kelly ; Ziegler Roland W., Device and method of attaching a blood pump and tubes to a surgical retractor.
Ralf Kaufmann DE; Christoph Nix DE; Gunter Rau DE; Helmut Reul DE, Device for conversion of a unidirectional rotational motion into reciprocating back and forth motion and pump device comprising same.
Moise John C. (Carmichael CA) Carriker John W. (Gold River CA) Baxter Reginald R. (Barrington IL), Drive mechanism for powering intravascular blood pumps.
Barbut Denise R. ; Patterson Russell H. ; Heinemann Mark-Hein, Endoscopic arterial pumps for treatment of cardiac insufficiency and venous pumps for right-sided cardiac support.
Watkins David H. (6039 N. Waterbury Road Des Moines IA 50312) Klink Erwin J. (814 Laurel Circle SE. Albuquerque NM 87108), Heart assist method and catheter.
Demarais, Denise M.; Leeflang, Stephen A.; Evans, Michael A.; Watanabe, Gwendolyn A.; Tanner, III, John C.; Eversull, Christian S., Mechanical pump for removal of fragmented matter and methods of manufacture and use.
Teirstein Paul S. (La Jolla CA) Nita Henry (Lake Forest CA) Dhuwalia Jagdish C. (Irvine CA) Evans Scott (Tustin CA), Method and device for exchanging cardiovascular guide catheter while a previously inserted angioplasty guide wire remain.
Bozeman ; Jr. Richard J. (Dickinson TX) Akkerman James W. (Houston TX) Aber Gregory S. (Houston TX) Damm George Arthur Van (Houston TX) Bacak James W. (Houston TX) Svejkovsky Paul A. (Webster TX) Ben, Method for reducing pumping damage to blood.
Romley Richard M. ; Donlon Brian S. ; Corvi Timothy J. ; Fan Sylvia W. ; Komtebedde Jan ; Lepulu Keke J. ; Lucatero Sylvester B., Methods and devices for cannulating a patient's blood vessel.
Ladika Joseph E. (2005 20th St. ; Ct. West Bradenton FL 33505) Tempkin David L. (647 Key Royal Dr. Holmes Beach FL 33510), Selective pulmonary arteriograph catheter.
Wampler Richard K. (Gold River CA) Carriker John W. (Gold River CA) Butler Kenneth C. (Carmichael CA) Moise John C. (Carmichael CA), Single-stage axial flow blood pump.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.