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다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
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Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0639766 (2011-04-07) |
등록번호 | US-9597487 (2017-03-21) |
국제출원번호 | PCT/US2011/031536 (2011-04-07) |
§371/§102 date | 20121005 (20121005) |
국제공개번호 | WO2011/127252 (2011-10-13) |
발명자 / 주소 |
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출원인 / 주소 |
|
대리인 / 주소 |
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인용정보 | 피인용 횟수 : 3 인용 특허 : 366 |
The present invention discloses multiple approaches to preventing the capsule walls and other material from interfering with the performance of an electronic device once the device is activated by surrounding fluid. In accordance with the teachings of the present invention, a miniature ingestible de
The present invention discloses multiple approaches to preventing the capsule walls and other material from interfering with the performance of an electronic device once the device is activated by surrounding fluid. In accordance with the teachings of the present invention, a miniature ingestible device (MID) may be created using excipients and films. The MID, in accordance with various aspects of the present invention, will have a coating or laminating surrounding an electronic device and separating and isolating the device from the pharmaceutical product or drug within the capsule once the capsule is ingested as well as from the capsule itself as the capsule walls begin to collapse during the disintegration process.
1. An apparatus, comprising: an ingestible device, including: a partial power source having a first portion and a second portion and configured to generate power upon contact of the first portion and the second portion with a fluid:a control unit electrically coupled between the first portion and th
1. An apparatus, comprising: an ingestible device, including: a partial power source having a first portion and a second portion and configured to generate power upon contact of the first portion and the second portion with a fluid:a control unit electrically coupled between the first portion and the second portion of the partial power source, wherein the control unit is configured to be activated by receiving the power from the partial power source and to encode information in a current flow between the first portion and the second portion through the fluid;a tablet material covering the first portion and the second portion of the partial power source and the control unit such that the tablet material isolates the first portion and the second portion of the partial power source and the control unit from a surrounding environment, wherein the tablet material is formulated to disintegrate upon contact with the fluid to expose the first portion and the second portion of the partial power source to the fluid;a non-soluble film material covering at least a portion of the tablet material, wherein the non-soluble film material is formulated and configured to inhibit interaction between the ingestible device and a pharmaceutical product during disintegration of the pharmaceutical product, and wherein the non-soluble film material covers the tablet material such that when the tablet material comes in contact with the fluid, the non-soluble film material controls the direction of expansion of the tablet material as the tablet material expands; anda capsule enveloping the ingestible device, wherein the tablet material further isolates the first portion and the second portion of the partial power source and the control unit from the capsule. 2. The apparatus of claim 1, wherein the tablet material comprises an excipient material that is a disintegrant and comprises at least one of: povidone, crospovidone, croscarmellose sodium, sodium starch glycolate, starch, or microcrystalline cellulose. 3. The apparatus of claim 1, wherein the tablet material is secured to the first portion and the second portion of the partial power source using pressure. 4. The apparatus of claim 1, wherein the tablet material is secured to the first portion and the second portion of the partial power source using an adhesive material. 5. The apparatus of claim 1, wherein the tablet material is secured to the first portion and the second portion of the partial power source using thermal application. 6. The apparatus of claim 1, wherein the tablet material surrounds the partial power source and is secured to itself to define a cavity between the tablet material and the partial power source. 7. The apparatus of claim 1, wherein the tablet material is a soluble film material that comprises at least one of polyethylene oxide or hydroxypropyl cellulose. 8. The apparatus of claim 1, further comprising the pharmaceutical product, and wherein the capsule comprises: a wall, wherein the wall defines a cavity for holding the pharmaceutical product wherein the wall loses its shape and disintegrates upon contact with the fluid, wherein the ingestible device is located within the cavity of the capsule, and wherein the cavity disintegrates upon contact with the fluid to provide physical separation between the ingestible device and the disintegrating wall of the capsule. 9. An apparatus, comprising: an ingestible unit comprising a first portion and a second portion configured to power and activate the ingestible unit upon contact with a fluid and to also encode information through the fluid, the ingestible unit configured to be disposed in a capsule suitable for ingestion;a tablet material covering one or more surfaces of the ingestible unit such that the tablet material separates the one or more surfaces of ingestible unit from a surrounding environment in the capsule; anda non-soluble film material covering at least a portion of the tablet material, wherein the non-soluble film material is formulated and configured to inhibit interaction between the ingestible unit and the capsule during disintegration of the capsule, and wherein the non-soluble film material covers the tablet material such that when the tablet material comes in contact with the fluid, the non-soluble film material controls the direction of expansion of the tablet material as the tablet material expands. 10. The apparatus of claim 9, wherein the ingestible unit comprises an ingestible event marker. 11. The apparatus of claim 10, wherein the tablet material comprises a disintegrant and comprises at least one of povidone, crospovidone, croscarmellose sodium, sodium starch glycolate, starch, or microcrystalline cellulose. 12. The apparatus of claim 11, wherein the disintegrant is physically coupled to the ingestible unit using pressure. 13. The apparatus of claim 11, wherein the disintegrant is physically coupled to the ingestible unit using an adhesive material. 14. The apparatus of claim 9, wherein the tablet material includes a soluble film material that comprises at least one of polyethylene oxide or hydroxypropyl. 15. The apparatus of claim 14, wherein the soluble film material is physically coupled to the ingestible unit using thermal application. 16. An apparatus comprising: an ingestible tablet configured for association with a pharmaceutical agent, wherein the ingestible tablet comprises: an ingestible device comprising a first portion and a second portion configured to power and activate the ingestible device upon contact with a fluid and to also encode information through the fluid;a tablet material in contact with at least part of the ingestible device; anda non-soluble film material covering at least a portion of the tablet material, wherein the non-soluble film material is formulated and configured to inhibit interaction between the ingestible device and the pharmaceutical agent during disintegration of the pharmaceutical agent, and wherein the non-soluble film material covers the tablet material such that when the tablet material comes in contact with the fluid, the non-soluble film material controls the direction of expansion of the tablet material as the tablet material expands. 17. The apparatus of claim 16, wherein the non-soluble film material delays contact between the fluid and the ingestible device to delay activation. 18. The apparatus of claim 16, wherein the apparatus further comprises a capsule defining a cavity, and wherein the ingestible tablet is located within the cavity of the capsule.
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