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[미국특허] Long-acting coagulation factors and methods of producing same 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12N-015/09
  • C12N-005/00
  • C07K-014/745
  • C12N-009/96
  • C12N-009/64
  • C07K-014/59
  • C07K-014/505
  • A61K-038/00
출원번호 US-0274061 (2014-05-09)
등록번호 US-9663778 (2017-05-30)
우선권정보 WO-PCT/IL2013/050107 (2012-02-05)
발명자 / 주소
  • Fima, Udi Eyal
  • Hart, Gili
출원인 / 주소
  • OPKO Biologies Ltd.
대리인 / 주소
    Cohen, Mark S.
인용정보 피인용 횟수 : 0  인용 특허 : 79

초록 ▼

Polypeptides comprising at least one carboxy-terminal peptide (CTP) of chorionic gonadotropin attached to the carboxy terminus but not to the amino terminus of a coagulation factor and polynucleotides encoding the same are disclosed. Pharmaceutical compositions comprising the polypeptides and polynu

대표청구항 ▼

1. A polynucleotide molecule consisting of a coding portion encoding a CTP-modified polypeptide consisting of a coagulation factor and three chorionic gonadotropin carboxy terminal peptides (CTPs) attached to the carboxy terminus of said coagulation factor, wherein said coagulation factor is Factor

이 특허에 인용된 특허 (79) 인용/피인용 타임라인 분석

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