[미국특허]
Method for dispensing ophthalmic fluid
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61F-009/00
B05B-011/00
B65D-081/24
B65B-003/00
출원번호
US-0313027
(2014-06-24)
등록번호
US-9668914
(2017-06-06)
발명자
/ 주소
Py, Daniel
Assion, Norbert M
Chan, Julian V
Ting, Joseph M
출원인 / 주소
DR. PY INSTITUTE LLC
대리인 / 주소
McCarter & English, LLP
인용정보
피인용 횟수 :
1인용 특허 :
256
초록▼
An ophthalmic dispenser and method of filling and dispensing fluid stored therein. The dispenser includes a rigid housing defining a fluid-receiving chamber, a flexible bladder receivable within the fluid-receiving chamber, a pump coupled in fluid communication with the fluid-receiving chamber, and
An ophthalmic dispenser and method of filling and dispensing fluid stored therein. The dispenser includes a rigid housing defining a fluid-receiving chamber, a flexible bladder receivable within the fluid-receiving chamber, a pump coupled in fluid communication with the fluid-receiving chamber, and a nozzle having a valve defining an annular, axially-extending valve seat, an outlet aperture coupled in fluid communication between the valve seat and the pump, and a flexible valve cover extending about the valve seat and forming an annular, axially-extending interface therebetween. The valve interface is connectable in fluid communication with the outlet aperture, and at least part of the valve cover is movable between (i) a normally closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to pumped fluid flowing through the outlet aperture at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. The rigid housing is mountable within a cartridge which, in turn, is mountable within a dispenser housing including an eyelid depressor and a trigger for simultaneously actuating the eyelid depressor and pump.
대표청구항▼
1. A method comprising: using a plurality of devices for aseptically receiving and dispensing substance, the plurality of devices being substantially identical to one another and each having a casing containing therein a sterile fluid chamber for receiving substance into the chamber and having a sea
1. A method comprising: using a plurality of devices for aseptically receiving and dispensing substance, the plurality of devices being substantially identical to one another and each having a casing containing therein a sterile fluid chamber for receiving substance into the chamber and having a sealed inlet thereof defined by a resealable portion, and an outlet for dispensing said substance out of the chamber, wherein the resealable portion is penetrable by an injection or filling member for introducing substance through the resealable portion and into the chamber, and is resealable to hermetically seal a penetrated region of the resealable portion after withdrawing the injection or filling member therefrom, said using step including installing at least one of the plurality of devices in a dispenser having an actuator configured to initiate dispensing; andusing at least one of the devices to dispense substance without installing the device in said dispenser. 2. A method as defined in claim 1, wherein the outlet, chamber and resealable portion are arranged in that order along a longitudinal axis moving in a direction toward a posterior end of the device. 3. A method comprising: providing a plurality of devices for aseptically receiving and dispensing substance, the plurality of devices being substantially identical to one another and each having a casing containing therein a sterile fluid chamber for receiving substance into the chamber and having a sealed inlet thereof defined by a resealable portion, and an outlet for dispensing said substance out of the chamber, wherein the resealable portion is penetrable by an injection or filling member for introducing substance through the resealable portion and into the chamber, and is resealable to hermetically seal a penetrated region of the resealable portion after withdrawing the injection or filling member therefrom,;providing a plurality of dispensers adapted to receive and operate the devices, the plurality of devices being substantially identical to one another and being capable of operation as a stand alone unit or in the dispenser;selling at least one of the devices in combination with at least one of the dispensers; andselling at least one of the devices without a dispenser. 4. A method for aseptically introducing substance into a device, the device comprising: a rigid housing defining a first sterile fluid-receiving chamber for receiving substance into the chamber and having a sealed inlet thereof defined by a resealable portion, and an outlet for dispensing said substance out of the chamber, wherein the resealable portion is penetrable by an injection or filling member for introducing substance through the resealable portion and into the chamber, and is resealable to hermetically seal a penetrated region of the resealable portion after withdrawing the injection or filling member therefrom, the method comprising the steps of: (i) penetrating the resealable portion with an injection or filling member;(ii) introducing substance into at least the first fluid-receiving chamber of the housing through the injection or filling member; and(iii) resealing the resealable portion, thereby hermetically sealing a penetrated region thereof. 5. A method as defined in claim 4, further comprising the steps of inserting a flexible bladder received within the first fluid-receiving chamber and collapsing the flexible bladder prior to inserting the bladder into the first fluid-receiving chamber of the housing. 6. A method as defined in claim 5, wherein the flexible bladder at least partially defines the first chamber. 7. A device for aseptically receiving and dispensing substance comprising: a rigid housing having a sterile fluid chamber therein for receiving substance into the chamber and having a sealed inlet thereof defined by a resealable portion, and an outlet for dispensing said substance out of the chamber;wherein the resealable portion is penetrable by an injection or filling member for introducing substance through the resealable portion and into the chamber, and is resealable to hermetically seal a penetrated region of the resealable portion after withdrawing the injection or filling member therefrom. 8. A device as define in claim 7, wherein the resealable portion comprises a resilient polymeric material. 9. A device as defined in claim 7, wherein substance within the chamber is sealed with respect to ambient atmosphere during dispensing of said substance through the outlet. 10. A device as defined in claim 7, further comprising an injection or filling member, coupled in fluid communication with a source of substance, configured to penetrate the resealable portion, and, in turn, to introduce said substance through the resealable portion and into the chamber. 11. A device as defined in claim 10, wherein the injection or filling member comprises a needle. 12. A device as defined in claim 7, wherein the resealable portion is resealable by application of radiation or energy thereto. 13. A device as defined in claim 12, wherein the radiation or energy comprises laser radiation. 14. A method of aseptically receiving into and dispensing substance from a device, the method comprising: penetrating with an injection or filling member a device comprising a rigid housing including a sterile fluid chamber therein for receiving substance into the chamber and having a sealed inlet thereof defined by a resealable portion, and an outlet for dispensing said substance out of the chamber, wherein the resealable portion is penetrable by a injection or filling member for introducing substance therethrough and into the chamber, and is resealable to hermetically seal a penetrated region of the resealable portion after withdrawing the injection or filling member therefrom;introducing substance from a source of said substance through the injection or filling member and into the chamber of the device; anddispensing said substance from the chamber through the outlet thereof. 15. A method as defined in claim 14, further comprising the step of withdrawing the injection or filling member from the resealable portion after said introducing step. 16. A method as defined in claim 15, further comprising, after said withdrawing step, the step of resealing the resealable portion, and, in turn, hermetically sealing a penetrated region thereof. 17. A method as defined in claim 16, wherein the resealable portion is resealable by application of radiation or energy thereto. 18. A method as defined in claim 17, wherein the radiation or energy comprises laser radiation. 19. A method as defined in claim 14, wherein the resealable portion comprises a resilient polymeric material. 20. A method as defined in claim 14, further comprising the step of maintaining substance within the chamber sealed with respect to ambient atmosphere during said dispensing step. 21. A method as defined in claim 14, wherein the injection or filling member comprises a needle.
Deininger Anton (Bachhagel DEX) Frber Karlheinz (Giengen/Brenz DEX) Giefer Heinz-Werner (Bergenweiler/Brenz DEX) Plester George (Essen GA DEX) Schorr Frederick D. (Decatur GA) Troska Georg (Herten DE, Apparatus for the dispensing of liquids in measured amounts.
Hillier Edward Lawrence (Ashland OH) Graham Glen Henry (Ashland OH) Eichelberger Warren Evan (Ashland OH), Blend of thermoelastic polymers with block radial polymers used as pharmaceutical sealing and resealing materials.
Bacehowski David V. (Wildwood IL) Bilstad Arnold C. (Deerfield IL) Fisher David (Antioch IL) Gliniecki Robert (Richmond IL) Keilman Michael R. (Diamond Lake IL) Smith Sidney T. (Lake Forest IL), Cell culture media flexible container.
Hansen Jeffrey E. ; Osakada Kunio,JPX ; Myers Michael J., Container and method of making container from polyethylene naphthalate and copolymers thereof.
Py, Daniel; Assion, Norbert; Houle, Nathaniel; Sahoo, Debashis; Willey, M. Jeffrey; Hartman, Eric E.; Guthy, John, Container closure with overlying needle penetrable and resealable portion and underlying portion compatible with fat containing liquid product, and related method.
Py, Daniel; Assion, Norbert; Houle, Nathaniel; Sahoo, Debashis; Willey, M. Jeffrey; Hartman, Eric E.; Guthy, John, Container closure with overlying needle penetrable and resealable portion and underlying portion compatible with fat containing liquid product, and related method.
Py, Daniel; Assion, Norbert; Houle, Nathaniel; Sahoo, Debashis; Willey, M. Jeffrey; Hartman, Eric E.; Guthy, John, Container closure with overlying needle penetrable and thermally resealable portion and underlying portion compatible with fat containing liquid product, and related method.
Lataix Gilbert (Clermont-Ferrand FRX), Device for the distribution of successive doses of a fluid product-in particular medicinal or cosmetic-contained in a vi.
Crosnier Daniel (14 rue Jacques Lanty 76550 Offranville FRX) Dulery Jean-Marie (53 avenue Pierre Semard 94210 La Varenne FRX), Device for total and immediate closure of bottle-like containers.
Crosnier Daniel (14 rue Jacques Lanty 76550 Offranville FRX) Dulery Jean-Marie (53 avenue Pierre Semard 94210 La Varenne FRX), Device for total and immediate closure which can be placed on various containers, bottles, tubes, jars, whether rigid or.
Gueret Jean-Louis H. (Paris FRX), Dispenser for at least one liquid or pasty product comprising a closure system that allows no ingress of air, and preser.
Hirschmann Adolf M. (Heilbronn DEX) Kser Klaus (Weinsberg DEX) Rieker Hans (Eberstadt DEX) Busch Hans-Peter (Heilbronn DEX) Rathke Willi (Erlenbach DEX) Maul Heinz P. (Eberstadt DEX), Dispenser for dispensing liquids in controlled quantities from a bottle.
Williams ; deceased John E. (late of Panorama City CA by Jayne Hughes Williams ; heir), Dispenser with compressible piston assembly for expelling product from a collapsible reservoir.
Roggenburg Stanley L. (Staten Island NY) Laauwe Robert H. (Franklin Lakes NJ) Polite John L. (Saddle River NJ) Tully Michael (Staten Island NY), Dispensing device.
Hazard Robert E. (511 Fletcher Rd. North Kingstown RI 02852-1612) Handren Frederick R. (2111 Jefferson Davis Hwy. ; Suite 409-S Arlington VA 22202), Dispensing pump with positive shut-off.
Hampel Hans-Joachim (Niederhchstadt DEX) Scondo Ludwig (Frankfurt am Main DEX) Stahl Jrgen (Frankfurt am Main DEX) Wegner Wilhelm (Frankfurt am Main DEX) Bonne Harry (Meilen CHX), Disposable container for liquids and apparatus for dispensing liquid from such container.
Meadows David L. (Mission Viejo CA) Kurjan Katherine C. (Huntington Beach CA) Branham Larry E. (San Juan Capistrano CA), Dropwise liquid dispensing system particularly suitable for liquids having low surface tension.
Shimizu Koji (Honjo JPX) Ehara Toshiyasu (Saitama JPX) Maruoka Kazumi (Saitama JPX) Yamagishi Kiyoshi (Kumagaya JPX), Filling/sealing apparatus for ampule or the like and method for monitoring this apparatus.
Haviv Shlomo (3750 Hudson Manor Ter. New York NY 10463) Hamilton Michael (5115 Fulton Ave. Sherman Oaks CA 91423), Fluid dispensing unit with one-way valve outflow.
Larsen Andre,DKX ; J.o slashed.rgensen Gabriel,DKX ; Jensen Peter Norland,DKX ; Flink James M.,DKX ; Klitgaard Peter Christian,DKX, Kit for storage and mixing of agents of which at least one is liquid.
Buckles Richard G. (Redwood City CA) Leeper Harold M. (Mountain View CA) Yum Su Il (Sunnyvale CA) Michaels Alan S. (Atherton CA), Liquid delivery device bladder.
Meador James W. (Houston TX) Miller Thomas G. (Houston TX) Nikirk Christopher T. (Houston TX) Waters ; Jr. Louis A. (Bellaire TX) Donnelly Sean M. (Houston TX), Liquid specimen transfer apparatus and method.
Turner Thomas R. (2262 Lusardi Dr. San Jose CA 94148) Kraemer Bernard M. (43555 Grimmer Blvd. #A210 Fremont CA 94533) Harrison Michael L. (1083 Di Napoli Dr. San Jose CA 95129), Medicament vial safety cap.
Duffey Craig L. (Galena OH) Estadt Charles A. (Groveport OH) Gerdeman Roger J. (Columbus OH), Method and apparatus for automatically filling and sterilizing containers.
Meyer Gabriel (Vesenaz CHX) Howald Ernst (Vesenaz CHX), Method for manufacturing a prefilled single-dose syringe and installation for carrying out the method.
Minshall Billy W. (Mission Viejo CA) Nygard John E. (Skokie IL) Sintim-Damoa Kwame (Vernon Hills IL) Giesler Richard (Deerfield IL) Woodworth Archie (Barrington IL) Purohit Kailash (Winnetka IL), Method for sterilizing.
Gerber, Bernard R.; Deb, Jyotirmay, Modular valve assembly and system with airtight, leakproof and shockproof closure for engagement in the neck of a container.
Gibbons Charles E. (Mobile AL) Marano Gerald A. (Mobile AL) Kittrell James M. (Mobile AL) Whillock Allan A. (Mobile AL) Lanham Robert L. (Mobile AL) Evans Donald (South Mobile AL), Oxygen impermeable leak free container.
Gibbons Charles E. (Mobile AL) Marano Gerald A. (Mobile AL) Kittrell James M. (Mobile AL) Whillock Allan A. (Mobile AL) Lanham Robert L. (Mobile AL) Evans Donald (South Mobile AL), Oxygen impermeable leak free container.
Su Cheh-Jen (Downers Grove IL) Tsai Boh C. (Rolling Meadows IL) Wachtel James A. (Buffalo Grove IL), Plastic containers for use in packaging and thermal processing of comestibles.
Packard Jeffrey (Grayslake IL) Schnell William J. (Libertyville IL) Scharf Michael W. (McHenry IL), Port and closure assembly including a resealing injection site for a container.
Libit Sidney M. (13244 Circulo Largo Ct. ; NE. Longboat Key FL) Libit Jeffrey M. (13244 Circulo Largo Ct. ; NE. Albuquerque NM 87112), Spray or dispensing bottle with integral pump molded therein.
Schmidt Steven L. (Merrimack NH) Collette Wayne N. (Merrimack NH) Krishnakumar Suppayan M. (Nashua NH), Squeezable multi-layer dispensing container with one-way valve.
Minshall Billy W. (Mission Viejo CA) Purohit Kailash (Winnetka IL) Nygard John E. (Skokie IL) Sintim-Damoa Kwame (Vernon Hills IL) Giesler Richard (Deerfield IL) Woodworth Archie (Barrington IL), Sterile product and method for sterilizing and assembling such product.
Howson David C. (Denver CO) Havranek Robert E. (Danville CA) Popken John A. (Longmont CO) Stone Frederick L. (Boulder CO), Storage receptacle sealing and transfer apparatus.
LeVeen Harry H. (321 Confederate Cir. Charleston SC 29407) LeVeen Robert F. (312 Lombard St. Philadelphia PA 19147) LeVeen Eric G. (3-3 Woodlike Rd. Albany NY 12203), Syringe.
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