최소 단어 이상 선택하여야 합니다.
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다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0716731 (2015-05-19) |
등록번호 | US-9687655 (2017-06-27) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 2 인용 특허 : 430 |
A leadless cardiac pacemaker comprises a hermetic housing, a power source disposed in the housing, at least two electrodes supported by the housing, a semiconductor temperature sensor disposed in the housing, and a controller disposed in the housing and configured to deliver energy from the power so
A leadless cardiac pacemaker comprises a hermetic housing, a power source disposed in the housing, at least two electrodes supported by the housing, a semiconductor temperature sensor disposed in the housing, and a controller disposed in the housing and configured to deliver energy from the power source to the electrodes to stimulate the heart based upon temperature information from the temperature sensor. In some embodiments, the sensor can be configured to sense temperature information within a predetermined range of less than 20 degrees C. The temperature sensor can be disposed in the housing but not bonded to the housing.
1. A leadless cardiac pacemaker comprising: an implantable hermetic housing;a power source disposed in the housing;at least two electrodes supported by the housing; anda bipolar transistor temperature sensor disposed in the housing, including at least one bi-polar transistor, and configured to produ
1. A leadless cardiac pacemaker comprising: an implantable hermetic housing;a power source disposed in the housing;at least two electrodes supported by the housing; anda bipolar transistor temperature sensor disposed in the housing, including at least one bi-polar transistor, and configured to produce a complimentary-to-absolute-temperature (CTAT) signal, a first proportional-to-absolute-temperature (PTAT) signal and a second PTAT signal;wherein the bipolar transistor temperature sensor also includes an analog-to-digital converter (ADC) configured to produce a digital temperature output in dependence on the CTAT signal and the first and second PTAT signals. 2. The leadless cardiac pacemaker of claim 1, wherein the bipolar transistor temperature sensor is configured to sense temperature information only between a first temperature and a second temperature, wherein a difference between the first and second temperatures is less than 20 degrees Celsius (C). 3. The leadless cardiac pacemaker of claim 2, wherein the first temperature is 36 degrees C. and the second temperature is 42 degrees C. 4. The leadless cardiac pacemaker of claim 1, wherein the ADC of the bipolar transistor temperature sensor is a low-resolution ADC adapted to consume less than 100 nA of current at greater than 0.1 temperature samples per second. 5. The leadless cardiac pacemaker of claim 1, wherein the ADC of the bipolar transistor temperature sensor is a low-resolution ADC adapted to consume approximately 50 nA of current at 0.2 temperature samples per second. 6. The leadless cardiac pacemaker of claim 1, wherein the ADC of the bipolar transistor temperature sensor is a charge balanced ADC. 7. The leadless cardiac pacemaker of claim 1, wherein the at least one bipolar transistor is configured to receive current from the power source and based thereon generate base-emitter voltages that are used to derive the CTAT signal and the first and second PTAT signals, the first PTAT signal being equal to the CTAT signal at a first temperature and the second PTAT signal being equal to the CTAT signal at a second different temperature; and further comprising a controller configured to scale the digital temperature output to a preferred temperature scale. 8. The leadless cardiac pacemaker of claim 7, wherein the at least one bipolar transistor is a single bipolar transistor, and wherein the first and second PTAT signals are derived from the single bipolar transistor to which first and second bias currents are successively applied. 9. The leadless cardiac pacemaker of claim 7, wherein the at least one bipolar transistor comprises: a first bipolar transistor configured to receive a first bias current from the power source and based thereon generate a first base-emitter voltage; anda second bipolar transistor configured to receive a second bias current from the power source and based thereon generate a second base-emitter voltage;wherein the first and second PTAT signals are derived from a difference between the first and second base-emitter voltages generated using the first and second bipolar transistors. 10. The leadless cardiac pacemaker of claim 7, wherein the ADC is further configured to balance a charge accumulated proportional to the CTAT signal by providing negative feedback with a charge proportional to the first or second PTAT signals. 11. The leadless cardiac pacemaker of claim 10, wherein the ADC is further configured to provide an intermediate signal configured to determine which of the first or second PTAT signals is used in the negative feedback path, such that a charge provided by the negative feedback path equals a charge provided by the CTAT signal. 12. The leadless cardiac pacemaker of claim 11, wherein an average value of the intermediate signal is equal to a relative value of the CTAT signal with respect to the first and second PTAT signals. 13. The leadless cardiac pacemaker of claim 1, wherein the bipolar transistor temperature sensor has a temperature-sensing resolution of one tenth of a degree Celsius and wherein the ADC of the bipolar transistor temperature sensor has approximately 6-bits of resolution. 14. The leadless cardiac pacemaker of claim 1, wherein the bipolar transistor temperature sensor has a temperature-sensing resolution of between 0.005° C. and 0.01° C. 15. The leadless cardiac pacemaker of claim 1, wherein the bipolar transistor temperature sensor has a temperature-sensing resolution of approximately 0.025° C. 16. The leadless cardiac pacemaker of claim 1, wherein the ADC is configured to digitize the CTAT signal with respect to the first and second PTAT signals to thereby enable the bipolar transistor temperature sensor to sense temperature over a predetermined temperature range that is less than 20 degrees Celsius (C). 17. The leadless cardiac pacemaker of claim 16, wherein the ADC is configured to produce the digital temperature output without digitizing a PTAT voltage with respect to a temperature-independent reference voltage. 18. The leadless cardiac pacemaker of claim 1, further comprising: a controller disposed in the housing and configured to deliver stimulation energy from the power source to the electrodes using the digital temperature output produced by the bipolar transistor temperature sensor. 19. The leadless cardiac pacemaker of claim 18, wherein the controller is also configured to scale the digital temperature output produced by the ADC to a preferred temperature scale selected from the group consisting of a Celsius scale, a Fahrenheit scale and a Kelvin scale. 20. A method of providing rate responsive stimulation to a patient's heart using a leadless pacemaker that includes a hermetic housing configured to be implanted within a patient, a power source disposed in the housing, a controller disposed within the housing, at least two electrodes supported by the housing, and a bipolar transistor temperature sensor disposed in the housing, the method comprising: using the bipolar transistor temperature sensor to produce a complimentary-to-absolute-temperature (CTAT) signal, a first proportional-to-absolute-temperature (PTAT) signal and a second PTAT signal;using an analog-to-digital converter (ADC) of the bipolar transistor temperature sensor to determine a temperature change in dependence on the CTAT signal and the first and second PTAT signals; andusing the controller disposed in the housing to deliver energy from the power source to the electrodes to stimulate the heart based upon the temperature change. 21. The method of claim 20, further comprising: using the power source to generate current;wherein using the bipolar transistor temperature sensor includes generating a base-emitter voltage based on the current, andderiving from the base-emitter voltage the CTAT signal and the first and second PTAT signals, wherein the first PTAT signal is approximately equal to the CTAT signal at a first temperature, and wherein the second PTAT signal is approximately equal to the CTAT signal at a second different temperature; andconverting the CTAT signal and the first and second PTAT signals into a digital temperature output signal using the ADC; andscaling the digital temperature output signal to represent a preferred temperature scale. 22. The method of claim 21, wherein the first and second temperatures correspond, respectively, to lower and upper bounds of a temperature range within which the bipolar transistor temperature sensor senses temperature information; and further comprising calibrating the bipolar transistor temperature sensor at a temperature between the first and second temperatures to establish an initial temperature error. 23. The method of claim 21, wherein using the power source to generate current includes generating a bias current; and further comprising correcting the bias current used to generate the CTAT signal to bring an initial temperature error within range of the ADC. 24. A leadless cardiac pacemaker comprising: an implantable housing that supports at least two electrodes;a power source disposed in the housing;a bipolar transistor temperature sensor configured to sense temperature information within a temperature range having a lower bound and an upper bound, the bipolar transistor temperature sensor including at least one bipolar transistor configured to receive current from the power source and based thereon generate base-emitter voltages that are used to derive a complimentary-to-absolute-temperature (CTAT) signal and first and second proportional-to-absolute-temperature (PTAT) signals, the first PTAT signal being equal to the CTAT signal at the lower bound of the temperature range and the second PTAT signal being equal to the CTAT signal at the upper bound of the temperature range; andthe bipolar transistor temperature sensor including an analog-to-digital converter (ADC) configured to produce a digital temperature output signal in dependence on the CTAT signal and the first and second PTAT signals. 25. The leadless cardiac pacemaker of claim 24, further comprising a controller disposed in the housing and configured to deliver energy from the power source to the electrodes based upon the digital temperature output signal produced by the ADC of the bipolar transistor temperature sensor.
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