[특허]Synthetic sealants

[미국특허] Synthetic sealants 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	C08L-015/00 A61K-008/72 A61K-031/77 A61L-024/04 C08G-018/50
출원번호	US-0883993 (2006-02-09)
등록번호	US-9707252 (2017-07-18)
국제출원번호	PCT/US2006/004500 (2006-02-09)
§371/§102 date	20080604 (20080604)
국제공개번호	WO2006/086510 (2006-08-17)
발명자 / 주소	Hadba, Ahmad R. Kennedy, John Roby, Mark
출원인 / 주소	Covidien LP
인용정보	피인용 횟수 : 0 인용 특허 : 130

초록 ▼

A biocompatible synthetic macromer composition is provided which includes a first polymer having stiffening linkages and at least one amine group, and a second component having at least one amine-reactive group. The biocompatible synthetic macromer composition can be used as an adhesive or sealant i

대표청구항 ▼

1. A biocompatible synthetic macromer composition comprising a first polymer of formula H2N—[R1-Q-R2]—NH2 (I) where R1 and R2 are the same or different and can be alkoxy or alkoxy with bioabsorbable groups, and Q is selected from the group consisting of bisphenol A, biphenyl, diglycidyl ethers of bisphenol A, ethoxylated bisphenol A, phenylene diamines, toluene diamine, and imides; a second component having amine-reactive groups of the formula R3(X)n (IV) wherein n>1, X is selected from the group consisting of succinimidyl groups, isocyanate groups, and combinations thereof, and R3 is derived from a compound selected from the group consisting of sorbitol, mannitol, dextran, cyclodextrin, polyalkylene oxides, polyethylene glycols with lactide linkages, and polyethylene oxide copolymers with polypropylene oxide; and, a coupling agent,wherein the composition has a viscosity from about 200 centipoise to about 100,000 centipoise. 2. A biocompatible synthetic macromer composition as in claim 1, wherein R1 or R2 is a polyethylene oxide. 3. A biocompatible synthetic macromer composition as in claim 1 wherein the bioabsorbable groups are derived from a compound selected from the group consisting of esters, aliphatic esters, carbonates, orthoesters, phosphoesters, glycolic acid, glycolide, lactic acid, lactide, 1,4-dioxane-2-one, 1,3-dioxane-2-one, ε-caprolactone, and combinations thereof. 4. A biocompatible synthetic macromer composition as in claim 1, wherein the first polymer is present in an amount from about 10% to about 90% by weight of the synthetic macromer composition. 5. A biocompatible synthetic macromer composition as in claim 1, wherein the second component is selected from the group consisting of di-functional polymers, tri-functional polymers, tetra-functional polymers, and mixtures thereof. 6. A biocompatible synthetic macromer composition as in claim 1, wherein the second component is a polyethylene glycol having multiple isocyanate groups. 7. A biocompatible synthetic macromer composition as in claim 1, wherein the second component is present in an amount from about 90% to about 10% by weight of the synthetic macromer composition. 8. A biocompatible synthetic macromer composition as in claim 1, wherein the first polymer is combined with hydrolytically degradable components. 9. A biocompatible synthetic macromer composition as in claim 1, wherein the first polymer is combined with enzymatically degradable components. 10. A biocompatible synthetic macromer composition as in claim 1, wherein the second component is combined with hydrolytically degradable components. 11. A biocompatible synthetic macromer composition as in claim 1, wherein the second component is combined with enzymatically degradable components. 12. A biocompatible synthetic macromer composition as in claim 1, wherein the coupling agent comprises a carbodiimide. 13. A biocompatible synthetic macromer composition as in claim 12, wherein the carbodiimide is 1-ethyl-3(3-dimethyl-aminopropyl)-carbodiimide hydrochloride. 14. An adhesive for wound closure comprising the biocompatible synthetic macromer composition of claim 1. 15. A sealant for use in a medical application comprising the biocompatible synthetic macromer composition of claim 1. 16. A biocompatible synthetic macromer composition as in claim 1, wherein the composition has a viscosity of from about 500 centipoise to about 10,000 centipoise.

이 특허에 인용된 특허 (130) 인용/피인용 타임라인 분석

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Harris J. Milton, Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution.
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Murray Kevin P. (Hoffman Estates IL) Ansel Robert E. (Hoffman Estates IL) Schmid Steven R. (Buffalo Grove IL), Strong and elastic polyurethane, polyurea, polyarylates and electron beam-cured coatings containing the same.
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Baichwal Anand, Sustained release heterodisperse hydrogel systems--amorphous drugs.
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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표IPC 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 공고번호, 공고일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표출원인, 출원인국적, 출원인주소, 발명자, 발명자E, 발명자코드, 발명자주소, 발명자 우편번호, 발명자국적, 대표IPC, IPC코드, 요약, 미국특허분류, 대리인주소, 대리인코드, 대리인(한글), 대리인(영문), 국제공개일자, 국제공개번호, 국제출원일자, 국제출원번호, 우선권, 우선권주장일, 우선권국가, 우선권출원번호, 원출원일자, 원출원번호, 지정국, Citing Patents, Cited Patents
저장형식	Text(ASCII format) Excel format PIAS분석(.xls)
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

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[미국특허] Synthetic sealants 원문보기

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