Real-time morphology analysis for lesion assessment
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61B-005/042
A61B-005/00
A61B-005/04
A61B-005/044
A61B-018/14
A61B-018/00
출원번호
US-0975197
(2015-12-18)
등록번호
US-9743854
(2017-08-29)
발명자
/ 주소
Stewart, Brian
Magen, Adam
Bennett, Nathan H.
Weisman, Michal
Hultz, Paul
출원인 / 주소
BOSTON SCIENTIFIC SCIMED, INC.
대리인 / 주소
Faegre Baker Daniels LLP
인용정보
피인용 횟수 :
0인용 특허 :
261
초록▼
Electrodes are used to measure an electrical signal (e.g., an electrogram). One or more filters are applied to the electrical signal to generate one or more filtered signals. Features of the filtered signals are evaluated to assess a sharpness corresponding to the electrical signal. Based on the sha
Electrodes are used to measure an electrical signal (e.g., an electrogram). One or more filters are applied to the electrical signal to generate one or more filtered signals. Features of the filtered signals are evaluated to assess a sharpness corresponding to the electrical signal. Based on the sharpness, various characteristics of a morphology of the electrogram may be evaluated over a time period.
대표청구항▼
1. A system comprising: a catheter including: a flexible catheter body having a distal portion; andat least one electrode disposed on the distal portion, the at least one electrode configured to measure an electrical signal based on a cardiac activation signal; anda mapping processor configured to:
1. A system comprising: a catheter including: a flexible catheter body having a distal portion; andat least one electrode disposed on the distal portion, the at least one electrode configured to measure an electrical signal based on a cardiac activation signal; anda mapping processor configured to: acquire the electrical signal from the at least one electrode;provide an electrogram based on the electrical signal;determine a sharpness feature associated with the electrogram and, based on the determined sharpness feature, determine a characteristic of a morphology of the electrogram, wherein the characteristic of the morphology of the electrogram is related to the sharpness. 2. The system of claim 1, wherein the catheter comprises an ablation catheter including a tissue ablation electrode configured to apply ablation energy to tissue, the system further comprising a radiofrequency (RF) generator operatively coupled to the tissue ablation electrode, wherein the RF generator is configured to generate the ablation energy and convey the generated ablation energy to the tissue ablation electrode, and wherein the mapping processor is configured to determine the sharpness before an ablation, during an ablation, and/or after an ablation. 3. The system of claim 1, further comprising a display device, wherein the mapping processor comprises: a filter configured to filter the electrical signal to generate a filtered signal;a feature detector configured to determine an amplitude of the filtered signal; andan output component configured to provide an output to the display device, wherein the output comprises the determined amplitude of the filtered signal. 4. The system of claim 3, wherein the amplitude comprises at least one of an absolute amplitude, a root-mean-squared (RMS) measurement, a peak-to-peak measurement, a maximum of a peak-to-peak measurement over a window, a percentile range measurement, a beat-gated measurement, and a free-running measurement. 5. The system of claim 3, wherein the filter is more responsive to high-frequency and/or quickly-varying components of the electrical signal than to low-frequency and/or slowly-varying components of the electrical signal. 6. The system of claim 3, wherein the filtered signal comprises an approximate derivative of the electrical signal. 7. The system of claim 3, wherein the filter includes a nonlinear processing element configured to attenuate one or more components of the electrical signal based on a polarity of a deflection of the electrical signal. 8. The system of claim 7, wherein the filter comprises a half-wave rectifier. 9. The system of claim 3, wherein the display device is configured to indicate a relative change in the amplitude of the filtered signal during a period of time. 10. The system of claim 3, wherein the display device is configured to display a waveform representing at least one of the filtered signal, an envelope of the filtered signal, an amplitude of the filtered signal, and a power of the filtered signal. 11. The system of claim 10, wherein the output component is configured to determine a combined signal comprising a combination of the filtered signal with an additional filtered signal, the waveform representing at least one of the combined signal, an envelope of the combined signal, an amplitude of the combined signal, and a power of the combined signal. 12. The system of claim 1, further comprising a display device, the mapping processor comprising: a first filter configured to filter the electrical signal across a first time scale to generate a first filtered signal, wherein the first filter comprises a first frequency response;a second filter configured to filter the electrical signal across a second time scale to generate a second filtered signal, wherein the second filter comprises a second frequency response, wherein at least a portion of the frequency response of the second filter is lower than a corresponding portion of the frequency response of the first filter;a feature detector configured to determine a feature corresponding to sharpness by analyzing the first and second filtered signals; andan output component configured to provide an output to the display device, wherein the output comprises the determined feature, wherein the display device is configured to depict a change in the determined feature over time. 13. The system of claim 12, wherein at least one of the first and second filters is configured to determine at least one of a time difference of the electrical signal, an approximate derivative of the electrical signal, a slope estimate across a time window, and a wavelet decomposition of the electrical signal. 14. The system of claim 12, wherein at least one of the first and second filters is more responsive to high-frequency and/or quickly-varying components of the electrical signal than to low-frequency and/or slowly-varying components of the electrical signal. 15. The system of claim 12, wherein the feature detector is configured to assess the sharpness of the electrical signal by comparing one or more levels of the first filtered signal with one or more levels of the second filtered signal to determine an amplitude-invariant measure of sharpness. 16. The system of claim 1, wherein the mapping processor is further configured to determine an overall morphology change of the electrogram based on a pre-ablation deflection template. 17. The system of claim 16, wherein the change in morphology is determined using at least one of a matched filter, a correlation, and a convolution with the pre-ablation deflection template or a signal derived therefrom. 18. A method for evaluating a condition of myocardial tissue, the method comprising: positioning a catheter adjacent to myocardial tissue within a patient's body, the catheter comprising: a flexible catheter body having a distal portion; andat least one electrode disposed on the distal portion, the at least one electrode configured to measure an electrical signal based on a cardiac activation signal;receiving the electrical signal;providing an electrogram based on the electrical signal;determining a sharpness feature of the electrogram;determining, based on the determined sharpness feature of the electrogram, a characteristic of a morphology of the electrogram, the characteristic of the morphology of the electrogram relating to the sharpness of the electrogram; anddisplaying an indication of at least one of the sharpness and the characteristic of the morphology, wherein the indication comprises at least one of a map, a light indicator, and a waveform. 19. The method of claim 18, further comprising: filtering the electrical signal across a first time scale, using a first filter, to generate a first filtered signal, wherein the first filter comprises a first frequency response;filtering the electrical signal across a second time scale, using a second filter, to generate a second filtered signal, wherein the second filter comprises a second frequency response, wherein at least a portion of the frequency response of the second filter is lower than a corresponding portion of the frequency response of the first filter;determining a feature corresponding to sharpness by analyzing the first and second filtered signals; andproviding an output to a display device, wherein the output comprises the determined feature, wherein the display device is configured to depict a change in the determined feature over time. 20. A system comprising: an ablation catheter including: a flexible catheter body having a distal portion;a tissue ablation electrode disposed on the distal portion of the flexible catheter body, wherein the tissue ablation electrode is configured to apply ablation energy to tissue;at least one electrode disposed on the distal portion, the at least one electrode configured to measure an electrical signal based on a cardiac activation signal; anda radiofrequency (RF) generator operatively coupled to the tissue ablation electrode and configured to generate the ablation energy to be conveyed to the tissue ablation electrode; anda mapping processor configured to: acquire the electrical signal from the at least one electrode;provide an electrogram based on the electrical signal;determine a sharpness feature associated with the electrogram and, based on the determined sharpness feature, determine a characteristic of a morphology of the electrogram, the characteristic relating to the sharpness.
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이 특허에 인용된 특허 (261)
Swanson, David K.; McGee, David; Panescu, Dorin; Whayne, James G.; TenHoff, Harm, Ablation and imaging catheter.
Lennox Charles D. (Hudson NH) Ropiak Susan M. (Hanscom Air Force Base MA) Roberts Troy W. (Arlington MA) Beaudet Stephen P. (Lexington MA), Ablation catheters.
Rankin, Darrell L.; Koblish, Josef V.; Deladi, Szabolcs, Ablation probe with fluid-based acoustic coupling for ultrasonic tissue imaging and treatment.
Hoey,Michael F.; Christopherson,Mark A.; Goetz,Steven M., Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue.
Edwards Stuart D. (San Ramon CA) Franz Michael R. (Washington DC) Thompson Russel B. (San Leandro CA) Stern Roger A. (Cupertino CA), Combination monophasic action potential/ablation catheter and high-performance filter system.
Swanson David K. ; Fleischman Sidney D. ; Kordis Thomas F. ; McGee David L., Composite structures and methods for ablating tissue to form complex lesion patterns in the treatment of cardiac conditions and the like.
Swanson,David K.; Fleischman,Sidney D.; Kordis,Thomas F.; McGee,David L., Composite structures and methods for ablating tissue to form complex lesion patterns in the treatment of cardiac conditions and the like.
Koblish, Josef V.; Thompson, Russell B.; Whayne, James G.; Yang, Yi; Swanson, David K.; Fleischman, Sidney D., Devices and methods for creating lesions in endocardial and surrounding tissue to isolate focal arrhythmia substrates.
Slater Charles R. (Fort Lauderdale FL) Palmer Matthew A. (Miami FL) Whittier John R. (Miami FL) Zwiefel Aaron R. (Miami FL), Edoscopic biopsy forceps devices with selective bipolar cautery.
Scampini,Steven; Peszynski,Michael; Salgo,Ivan; Savord,Bernard, Guidance of invasive medical devices by high resolution three dimensional ultrasonic imaging.
Peszynski, Michael; Salgo, Ivan; Savord, Bernard; Scampini, Steven, Guidance of invasive medical devices by wide view three dimensional ultrasonic imaging.
Paul, Saurav; Belhe, Kedar Ravindra; Cao, Hong; Thao, Chou; Hassett, James A., Handle set for ablation catheter with indicators of catheter and tissue parameters.
Naples Gregory G. (Brecksville OH) Sweeney James D. (Cleveland Heights OH) Mortimer J. Thomas (Cleveland Heights OH), Implantable cuff, method of manufacture, and method of installation.
Clare Christopher R. (Los Altos Hills CA) Imran Mir A. (Palo Alto CA) Barnett ; Jr. Donald E. (Sunnyvale CA) Highe Albert J. (Redwood City CA), Large surface area electrode.
Maguire, Mark A.; O'Sullivan, Martin F.; Carcamo, Edward L.; Lesh, Michael D.; Schaer, Alan K.; Taylor, Kevin J.; Picazo, Guillermo P., Medical device with sensor cooperating with expandable member.
Loftman, Rickard C.; Schlesinger, Randall L.; Jackson, John I.; Garbini, Lex J.; Dull, Douglas B., Medical diagnostic ultrasound catheter with first and second tip portions.
Goldreyer Bruce N. (30311 Palos Verdes Dr. East Rancho Palos Verdes CA 90275), Method and apparatus for spatially specific electrophysiological sensing in a catheter with an enlarged ablating electro.
Marchlinski Francis E. (Bala Cynwyd PA) Schwartzman David S. (Philadelphia PA) Mirotznik Mark S. (Silver Spring MD) Foster Kenneth R. (Haverford PA) Gottleb Charles D. (Wynnewood PA) Chang Isaac (Phi, Method of using endocardial impedance for determining electrode-tissue contact, appropriate sites for arrhythmia ablatio.
Silverstein Fred E. (1246 - 15th Ave. E. Seattle WA 98112) Proctor Andrew H. (32527 NE. 120th St. Duvall WA 98019), Miniature ultrasound imaging probe.
Swanson, David K.; Hegde, Anant V.; Hartzog, Anna; McMillan, Alan; O'Brien, Dennis, Probe assembly for mapping and ablating pulmonary vein tissue and method of using same.
Bennett Tom D. (Shoreview MN) Combs William J. (Eden Prairie MN) Kallok ; Michael J. (New Brighton MN) Lee Brian B. (Golden Valley MN) Mehra Rahul (Stillwater MN) Klein George J. (London CAX), Subcutaneous multi-electrode sensing system, method and pacer.
Deno, Don Curtis; Miller, Stephan P.; Hill, Lewis C.; Malinin, Yuriy; Sih, Haris J., System and method for assessing coupling between an electrode and tissue.
Deno, Don Curtis; Miller, Stephan P.; Hill, Lewis C; Malinin, Yuriy; Sih, Haris, System and method for assessing coupling between an electrode and tissue.
Fish, Jeffrey M.; Byrd, Israel A.; Clark, Lynn E.; Dando, Jeremy D.; Geurkink, Christopher J.; Puryear, Harry A.; Paul, Saurav, System and method for assessing the formation of a lesion in tissue.
Wilfley, Brian P.; Heanue, Joseph A.; Friedman, Stuart L., System and method for determining electrode-tissue contact based on amplitude modulation of sensed signal.
Wilfley, Brian P.; Heanue, Joseph A.; Friedman, Stuart L., System and method for determining electrode-tissue contact based on amplitude modulation of sensed signal.
Gilboa, Pinhas; Tolkowsky, David; Hollander, David, System and method for determining the location of a catheter during an intra-body medical procedure.
Panescu Dorin (Sunnyvale CA) Swanson David K. (Mountain View CA), System and methods for matching electrical characteristics and propagation velocities in cardiac tissue.
Panescu Dorin ; Lesh Michael D. ; Swanson David K. ; Whayne James G., Systems and methods for analyzing cardiac biopotential morphologies by cross-correlation.
Panescu Dorin (Sunnyvale CA) Swanson David K. (Mountain View CA), Systems and methods for deriving electrical characteristics of cardiac tissue for output in iso-characteristic displays.
Swanson David K. (Mountain View CA) Bourne Thomas (Mountain View CA) Fleischman Sidney D. (Menlo Park CA) Panescu Dorin (Sunnyvale CA) Whayne James G. (Saratoga CA), Systems and methods for forming large lesions in body tissue using curvilinear electrode elements.
Panescu Dorin ; Swanson David K. ; Whayne James G. ; Thompson Russell B. ; Owens Patrick M., Systems for heating and ablating tissue using multifunctional electrode structures.
Bonnefous, Odile, Ultrasonic image processing method and examination system for displaying an ultrasonic color-coded image sequence of an object having moving parts.
Lancee Charles T. (Waarder NLX) Bom Nicolaas (Berkenwoude NLX), Ultrasonic instrument with a micro motor having stator coils on a flexible circuit board.
Manna, Ronald R.; Voic, Dan; Novak, Theodore A. D.; Isola, Scott; Darian, Alexander L., Ultrasonic medical treatment device for bipolar RF cauterization and related method.
Kazi Arif (Bensheim DEX) Rougeot Jeanne (Montreal CAX) Li Lynn L. (Montreal CAX) Dufour Louis D. (Longueuil CAX), Ultrasound catheter with mechanically steerable beam.
Levrier,Claire; Cohen Bacrie,Claude; Villain,Nicholas; Lagrange,Jean Michel; Entrekin,Robert R., Ultrasound imaging system with a high lateral resolution.
Thiele, Karl Erhard; Solomon, Rodney J.; Adleman, George; Savord, Bernard, Ultrasound-imaging systems and methods for a user-guided three-dimensional volume-scan sequence.
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