A drug delivery device, including a body having a reservoir disposed therein for containing a medicament, the reservoir including a flexible wall; a plunger movable within the body for causing the medicament to be expelled from the reservoir, the plunger having a contact surface that is not affixed
A drug delivery device, including a body having a reservoir disposed therein for containing a medicament, the reservoir including a flexible wall; a plunger movable within the body for causing the medicament to be expelled from the reservoir, the plunger having a contact surface that is not affixed to said flexible reservoir wall; a spring biasing the plunger toward the reservoir; and means for selectively maintaining the plunger in a pre-activated position with respect to the reservoir and, upon releasing the plunger from the pre-activated position, for guiding the plunger to move under the force of the spring such that the contact surface of the plunger contacts the flexible reservoir wall to pressurize the reservoir for delivery of the medicament to a patient.
대표청구항▼
1. A medicament delivery device, comprising: a body having a reservoir disposed therein for containing a medicament, the reservoir including a flexible reservoir wall;a plunger movable within the body for causing the medicament to be expelled from the reservoir, the plunger having a contact surface
1. A medicament delivery device, comprising: a body having a reservoir disposed therein for containing a medicament, the reservoir including a flexible reservoir wall;a plunger movable within the body for causing the medicament to be expelled from the reservoir, the plunger having a contact surface that is not affixed to said flexible reservoir wall;a spring biasing the plunger in a pre-activated position toward the reservoir; andmeans for selectively maintaining the plunger in the pre-activated position with respect to the reservoir and, upon releasing the plunger from the pre-activated position, for guiding the plunger to move under a force of the spring such that the contact surface of the plunger contacts the flexible reservoir wall to pressurize the reservoir for delivery of the medicament to a patient;wherein the means for selectively maintaining the plunger in the pre-activated position with respect to the reservoir and, upon releasing the plunger from the pre-activated position, for guiding the plunger, comprises:a retention plate disposed within the body, wherein the spring is disposed between the retention plate and the plunger;first guide means provided on one of the retention plate and the plunger, the first guide means having a portion with a predetermined size and shape; andsecond guide means provided on the other one of the retention plate and the plunger and having a size and shape complementary to the size and shape of the portion of the first guide means, the first guide means and the second guide means maintaining the plunger in a first position with respect to the reservoir;wherein upon activation of the device, one of the retention plate and the plunger rotates with respect to a non-rotating one of the retention plate and the plunger such that the first guide means aligns with the second guide means causing the plunger to be released from the first position and allowing the plunger to move under the force of the spring to pressurize the reservoir for delivery of the medicament to a patient. 2. The device according to claim 1, wherein: the first guide means comprises a post disposed at substantially a center of the one of the retention plate and the plunger, and the portion with the predetermined size and shape comprises a sprocket disposed at a distal end of the post;the second guide means comprises an opening with a shape and size corresponding to the sprocket, the opening having slots interposed between fingers of the other one of the retention plate and the plunger; andupon activation of the device, the rotation of the rotating one of the retention plate and the plunger aligns teeth of the sprocket with the slots of the opening to release the plunger. 3. The device according to claim 2, wherein in a pre-activated position, the teeth of the sprocket align with the fingers to maintain compression of the spring. 4. The device according to claim 2, wherein the post and the one of the retention plate and the plunger where the post is disposed are integrally formed as a unitary structure. 5. The device according to claim 2, further comprising an activator button movably disposed on the body and movable from a pre-activated position to an activated position; wherein moving the activator button from the pre-activated position to the activated position causes rotation of one of the retention plate and the plunger to align the teeth of the sprocket with the slots of the opening. 6. The device according to claim 5, wherein: the plunger comprises at least one plunger tab extending from an outer edge thereof;the body comprises a substantially cylindrical housing having at least one recessed channel to guide the at least one plunger tab during plunger movement under the force of the spring to pressurize the reservoir;the reservoir is disposed within the substantially cylindrical housing; andthe drug delivery device further comprises an injection needle for penetrating the skin of a patient, the injection needle providing a path for the medicament between the reservoir and the patient. 7. The device according to claim 6, further comprising a valve disposed between the reservoir and the injection needle to selectively permit delivery of the medicament from the reservoir to the injection needle; wherein moving the activator button from the pre-activated position to the activated position causes the valve to open to permit delivery of the medicament from the reservoir to the injection needle. 8. The device according to claim 6, further comprising a rotor rotatably disposed about the substantially cylindrical housing; wherein moving the activator button from the pre-activated position to the activated position causes rotation of the rotor, which contacts the at least one tab and rotates the plunger to align the teeth of the sprocket with the slots of the opening. 9. The device according to claim 8, wherein the post is disposed on the retention plate. 10. The device according to claim 8, wherein the post is disposed on the plunger. 11. The device according to claim 6, wherein moving the activator button from the pre-activated position to the activated position causes rotation of the retention plate to align the teeth of the sprocket with the slots of the opening. 12. The device according to claim 11, wherein the post is disposed on the retention plate. 13. The device according to claim 11, wherein the post is disposed on the plunger. 14. The device according to claim 11, further comprising a drive spring movable from a pre-activated position to an activated position; wherein the retention plate rotates from a pre-activated position to an activated position and includes a drive spring holder supporting the drive spring in the respective pre-activated positions of the retention plate and the drive spring; andwherein moving the activator button from the pre-activated position to the activated position causes rotation of the retention plate to the activated position, releasing the drive spring to move to the activated position to drive the injection needle to penetrate the skin of the patient. 15. A wearable medicament delivery device, comprising: a body having a reservoir disposed therein for containing a medicament, the reservoir including a flexible reservoir wall;a plunger movable within the body for causing the medicament to be expelled from the reservoir, the plunger having a contact surface that is not affixed to said flexible reservoir wall;a spring biasing the plunger in a pre-activated position toward the reservoir; andmeans for selectively maintaining the plunger in the pre-activated position with respect to the reservoir and, upon releasing the plunger from the pre-activated position, for guiding the plunger to move under a force of the spring such that the contact surface of the plunger contacts the flexible reservoir wall to pressurize the reservoir for delivery of the medicament to a patient; andan adhesive disposed on a surface of the infusion device, the adhesive being adapted to attach the device to a skin surface of a patient, enabling the patient to wear the device during medicament delivery over an extended period of time;wherein the means for selectively maintaining the plunger in the pre-activated position with respect to the reservoir and, upon releasing the plunger from the pre-activated position, for guiding the plunger, comprises a housing disposed within the body, the plunger and spring being disposed within the housing;wherein the plunger includes at least one tab extending from an outer edge thereof and moving axially therewith; andwherein the housing includes at least one opening with a tab engaging portion for selectively engaging the plunger tab and at least one recessed channel for guiding the at least one plunger tab during plunger movement under the force of the spring to pressurize the reservoir. 16. The device according to claim 15, wherein the at least one opening in the housing comprises an L-shaped opening having a vertical portion substantially aligned with the recessed channel, and a horizontal portion including the tab engaging portion. 17. The device according to claim 15, wherein in the pre-activated position of the plunger, the spring biases the tab against the tab engaging portion. 18. The device according to claim 15, wherein in the pre-activated position of the plunger, the tab engaging portion prevents the spring and the plunger from pressurizing the reservoir. 19. A medicament delivery device, comprising: a body having a reservoir disposed therein for containing a medicament, the reservoir including a flexible reservoir wall;a plunger movable within the body for causing the medicament to be expelled from the reservoir, the plunger having a contact surface that is not affixed to said flexible reservoir wall;a spring biasing the plunger in a pre-activated position toward the reservoir;means for selectively maintaining the plunger in the pre-activated position with respect to the reservoir and, upon releasing the plunger from the pre-activated position, for guiding the plunger to move under a force of the spring such that the contact surface of the plunger contacts the flexible reservoir wall to pressurize the reservoir for delivery of the medicament to a patient; anda rotor rotatably disposed about the housing and being rotatable between a pre-activated position and an activated position;wherein the means for selectively maintaining the plunger in the pre-activated position with respect to the reservoir and, upon releasing the plunger from the pre-activated position, for guiding the plunger, comprises a housing disposed within the body, the plunger and spring being disposed within the housing;wherein the plunger includes at least one tab extending from an outer edge thereof;wherein the housing includes at least one opening with a tab engaging portion for selectively engaging the plunger tab and at least one recessed channel for guiding the at least one plunger tab during plunger movement under the force of the spring to pressurize the reservoir; andwherein during rotation from the pre-activated position to the activated position, a tab engaging surface of the rotor rotates the plunger tab from engagement with the tab engaging portion of the housing to alignment with the recessed channel, thereby permitting the plunger to move under the force of the spring to pressurize the reservoir for delivery of the medicament to a patient. 20. A medicament delivery device, comprising: a body having a reservoir disposed therein for containing a medicament;a plunger movable within the body for causing the medicament to be expelled from the reservoir;a spring biasing the plunger in a pre-activated position toward the reservoir;a retention plate disposed within the body, wherein the spring is disposed between the retention plate and the plunger;a first guide unit provided on one of the retention plate and the plunger, the first guide unit having a portion with a predetermined size and shape; anda second guide unit provided on the other one of the retention plate and the plunger and having a size and shape complementary to the size and shape of the first guide unit, the first guide unit and the second guide unit maintaining the plunger in a first position with respect to the reservoir;wherein upon activation of the device, one of the retention plate and the plunger rotates with respect to a non-rotating one of the retention plate and the plunger such that the first guide unit aligns with the second guide unit causing the plunger to be released from the first position and allowing the plunger to move under the force of the spring to pressurize the reservoir for delivery of the medicament to a patient. 21. A medicament delivery device, comprising: a body having a reservoir disposed therein for containing a medicament, the reservoir including a flexible wall;a plunger movable within the body for causing the medicament to be expelled from the reservoir, the plunger having at least one tab extending from an outer edge thereof and moving axially therewith, and a contact surface that is not affixed to said flexible reservoir wall;a spring biasing the plunger in a pre-activated position toward the reservoir;a valve connecting the reservoir with a patient needle; anda housing disposed within the body, the plunger and spring being disposed within the housing;wherein the housing includes at least one opening with a tab engaging portion for selectively engaging the plunger tab for maintaining the plunger in a pre-activated position, the housing also including at least one recessed channel for guiding the at least one plunger tab upon releasing the plunger from the pre-activated position, to move under the force of the spring such that the contact surface of the plunger contacts the flexible reservoir wall to pressurize the reservoir for delivery of the medicament to a patient;wherein the valve is disposed outside the housing.
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